The Intrinsic Absorber in QSO 2359-1241: Keck and HST Observations

We present detailed analyses of the absorption spectrum seen in QSO 2359-1241 (NVSS J235953-124148). Keck HIRES data reveal absorption from twenty transitions arising from: He I, Mg I, Mg II, Ca II, and Fe II. HST data show broad absorption lines (BALs) from Al III 1857, C IV 1549, Si IV 1397, and N V 1240. Absorption from excited Fe II states constrains the temperature of the absorber to 2000K < T < 10,000K and puts a lower limit of 10^5 cm^{-3} on the electron number density. Saturation diagnostics show that the real column densities of He I and Fe II can be determined, allowing to derive meaningful constraints on the ionization equilibrium and abundances in the flow. The ionization parameter is constrained by the iron, helium and magnesium data to -3.0 < log(U) < -2.5 and the observed column densities can be reproduced without assuming departure from solar abundances. From comparison of the He I and Fe II absorption features we infer that the outflow seen in QSO 2359-1241 is not shielded by a hydrogen ionization front and therefore that the existence of low-ionization species in the outflow (e.g., Mg II, Al III, Fe II) does not necessitate the existence of such a front. We find that the velocity width of the absorption systematically increases as a function of ionization and to a lesser extent with abundance. Complementary analyses of the radio and polarization properties of the object are discussed in a companion paper (Brotherton et al. 2000).Comment: 30 pages, 9 figures, in press with the Ap

Keck Hires Observations of the QSO First J104459.6+365605: Evidence for a Large Scale Outflow

This paper presents an analysis of a Keck HIRES spectrum of the QSO FIRST J104459.6+365605. The line of sight towards the QSO contains two clusters of outflowing clouds that give rise to broad blue shifted absorption lines. The outflow velocities of the clouds range from -200 to -1200 km/s and from -3400 to -5200 km/s, respectively. The width of the individual absorption lines ranges from 50 to more than 1000 km/s. The most prominent absorption lines are those of Mg II, Mg I, and Fe II. The low ionization absorption lines occur at the same velocities as the most saturated Mg II lines, showing that the Fe II, Mg I and Mg II line forming regions must be closely associated. Many absorption lines from excited states of Fe II are present, allowing a determination of the population of several low lying energy levels. From this we determine an electron density in the Fe II line forming regions of 4000 per cubic cm. Modelling the ionization state of the absorbing gas with this value of the electron density as a constraint, we find that the distance between the Fe II and Mg I line forming region and the continuum source is of order 700 parsec. From the correspondence in velocity between the Fe II, Mg I and Mg II lines we infer that the Mg II lines must be formed at the same distance. The Mg II absorption fulfills the criteria for Broad Absorption Lines defined by Weymann et al. (1991). This large distance is surprising, since BALs are generally thought to be formed in outflows at a much smaller distance from the nucleus.Comment: 34 pages, 11 figures. Accepted by The Astrophysical Journa

Mode Competition in Relativistic Magnetrons and Injection Locking in KW Magnetrons

Both relativistic and nonrelativistic magnetrons are under experimental and theoretical investigation at U of M. Relativistic (Titan‐6‐vane) magnetron experiments (300–400 kV, 1–10 kA, 0.5 microsecond) investigate mode control with various output coupling geometries. Mode competition between the pi mode and the 2/3 pi mode has been characterized for two‐versus‐three output extractors for comparison with particle in cell simulations. Phase measurements and time‐frequency‐analysis are performed for mode identification. Peak microwave output power on the order 0.5 GW has been measured, assuming equal output from 3 waveguides. Nonrelativistic (4 kV, <1A, kW microwave power) magnetron experiments are performed on commercial oven magnetrons for an in‐depth investigation of crossed‐field injection‐locking and noise. Injection‐locking is demonstrated by utilizing an oven magnetron as a reflection amplifier. Noise generation is explored as a function of injected signal and cathode conditions. © 2003 American Institute of PhysicsPeer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/87505/2/301_1.pd

Decomposing complex thin-walled CAD models for hexahedral-dominant meshing

AbstractThis paper describes an automatic method for identifying thin-sheet regions (regions with large lateral dimensions relative to the thickness) for complex thin walled components, with a view to using this information to guide the hex meshing process. This fully automated method has been implemented in a commercial CAD system (Siemens NX) and is based on the interrogation and manipulation of face pairs, which are sets of opposing faces bounding thin-sheet regions. Careful consideration is given to the mapping, merging and intersection of face pairs to generate topologies suitable for sweep meshing thin-sheet regions, and for treating the junctions between adjacent thin-sheet regions. The quality of the resulting hexahedral mesh is considered when making decisions on the generation and positioning of the cutting surfaces required to isolate thin-sheet regions. The resulting decomposition delivers a substantial step towards automatic hexahedral meshing for complex thin-walled geometries. It is proposed that hexahedral meshes be applied to the identified thin-sheet regions by quad meshing one of the faces bounding the thin-sheet region and sweeping it through the thickness to create hexahedral elements

First observations of separated atmospheric nu_mu and bar{nu-mu} events in the MINOS detector

The complete 5.4 kton MINOS far detector has been taking data since the beginning of August 2003 at a depth of 2070 meters water-equivalent in the Soudan mine, Minnesota. This paper presents the first MINOS observations of nuµ and [overline nu ]µ charged-current atmospheric neutrino interactions based on an exposure of 418 days. The ratio of upward- to downward-going events in the data is compared to the Monte Carlo expectation in the absence of neutrino oscillations, giving Rup/downdata/Rup/downMC=0.62-0.14+0.19(stat.)±0.02(sys.). An extended maximum likelihood analysis of the observed L/E distributions excludes the null hypothesis of no neutrino oscillations at the 98% confidence level. Using the curvature of the observed muons in the 1.3 T MINOS magnetic field nuµ and [overline nu ]µ interactions are separated. The ratio of [overline nu ]µ to nuµ events in the data is compared to the Monte Carlo expectation assuming neutrinos and antineutrinos oscillate in the same manner, giving R[overline nu ][sub mu]/nu[sub mu]data/R[overline nu ][sub mu]/nu[sub mu]MC=0.96-0.27+0.38(stat.)±0.15(sys.), where the errors are the statistical and systematic uncertainties. Although the statistics are limited, this is the first direct observation of atmospheric neutrino interactions separately for nuµ and [overline nu ]µ

Mariana serpentinite mud volcanism exhumes subducted seamount materials: implications for the origin of life

The subduction of seamounts and ridge features at convergent plate boundaries plays an important role in the deformation of the overriding plate and influences geochemical cycling and associated biological processes. Active serpentinization of forearc mantle and serpentinite mud volcanism on the Mariana forearc (between the trench and active volcanic arc) provides windows on subduction processes. Here, we present (1) the first observation of an extensive exposure of an undeformed Cretaceous seamount currently being subducted at the Mariana Trench inner slope; (2) vertical deformation of the forearc region related to subduction of Pacific Plate seamounts and thickened crust; (3) recovered Ocean Drilling Program and International Ocean Discovery Program cores of serpentinite mudflows that confirm exhumation of various Pacific Plate lithologies, including subducted reef limestone; (4) petrologic, geochemical and paleontological data from the cores that show that Pacific Plate seamount exhumation covers greater spatial and temporal extents; (5) the inference that microbial communities associated with serpentinite mud volcanism may also be exhumed from the subducted plate seafloor and/or seamounts; and (6) the implications for effects of these processes with regard to evolution of life.Copyright 2020 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/ by/4.0/, which permits unrestricted use, provided the original author and source are credited

Atomoxetine Enhances Connectivity of Prefrontal Networks in Parkinson's Disease.

Cognitive impairment is common in Parkinson's disease (PD), but often not improved by dopaminergic treatment. New treatment strategies targeting other neurotransmitter deficits are therefore of growing interest. Imaging the brain at rest ('task-free') provides the opportunity to examine the impact of a candidate drug on many of the brain networks that underpin cognition, while minimizing task-related performance confounds. We test this approach using atomoxetine, a selective noradrenaline reuptake inhibitor that modulates the prefrontal cortical activity and can facilitate some executive functions and response inhibition. Thirty-three patients with idiopathic PD underwent task-free fMRI. Patients were scanned twice in a double-blind, placebo-controlled crossover design, following either placebo or 40-mg oral atomoxetine. Seventy-six controls were scanned once without medication to provide normative data. Seed-based correlation analyses were used to measure changes in functional connectivity, with the right inferior frontal gyrus (IFG) a critical region for executive function. Patients on placebo had reduced connectivity relative to controls from right IFG to dorsal anterior cingulate cortex and to left IFG and dorsolateral prefrontal cortex. Atomoxetine increased connectivity from the right IFG to the dorsal anterior cingulate. In addition, the atomoxetine-induced change in connectivity from right IFG to dorsolateral prefrontal cortex was proportional to the change in verbal fluency, a simple index of executive function. The results support the hypothesis that atomoxetine may restore prefrontal networks related to executive functions. We suggest that task-free imaging can support translational pharmacological studies of new drug therapies and provide evidence for engagement of the relevant neurocognitive systems.This work was funded by the Wellcome trust (103838), Parkinson’s UK, National Institute for Health Research’s Cambridge Biomedical Research Centre and the Medical Research Council (MC_US_A060_0016 and RG62761) and the James F McDonnell Foundation (21st century science initiative on Understanding Human Cognition). The BCNI is supported by a joint award from the Wellcome Trust and Medical Research Council.This is the final version of the article. It first appeared from Nature Publishing Group via http://dx.doi.org/10.1038/npp.2016.1

The KMOS3D Survey: Demographics and Properties of Galactic Outflows at z=0.6-2.7

We present a census of ionized gas outflows in 599 normal galaxies at redshift 0.6 < z < 2.7, mostly based on integral field spectroscopy of H alpha, [N II], and [S II] line emission. The sample fairly homogeneously covers the main sequence of star-forming galaxies with masses 9.0 < log(M-*/M-circle dot) < 11.7, and probes into the regimes of quiescent galaxies and starburst outliers. About one-third exhibits the high-velocity component indicative of outflows, roughly equally split into winds driven by star formation (SF) and active galactic nuclei (AGNs). The incidence of SF-driven winds correlates mainly with SF properties. These outflows have typical velocities of similar to 450 km s(-1), local electron densities of n(e) similar to 380 cm(-3), modest mass loading factors of similar to 0.1-0.2 at all galaxy masses, and energetics compatible with momentum driving by young stellar populations. The SF-driven winds may escape from log(M-*/M-circle dot) less than or similar to 10.3 galaxies, but substantial mass, momentum, and energy in hotter and colder outflow phases seem required to account for low galaxy formation efficiencies in the low-mass regime. Faster AGN-driven outflows (similar to 1000-2000 km s(-1)) are commonly detected above log(M-*/M-circle dot) similar to 10.7, in up to similar to 75% of log(M-*/M-circle dot) greater than or similar to 11.2 galaxies. The incidence, strength, and velocity of AGN-driven winds strongly correlates with stellar mass and central concentration. Their outflowing ionized gas appears denser (n(e) similar to 1000 cm(-3)), and possibly compressed and shock-excited. These winds have comparable mass loading factors as the SF-driven winds but carry similar to 10 (similar to 50) times more momentum (energy). The results confirm our previous findings of high-duty-cycle, energy-driven outflows powered by AGN above the Schechter mass, which may contribute to SF quenching.E.S.W. and J.T.M. acknowledge support by the Australian Research Council Center of Excellence for All Sky Astrophysics in Three Dimensions (ASTRO 3D), through project number CE170100013. D.J.W. and M.F. acknowledge the support of the Deutsche Forschungsgemeinschaft via Project ID 3871/1-1 and 3871/1-2. G.B.B. acknowledges support from the Cosmic Dawn Center, which is funded by the Danish National Research Foundation

Self-love and sociability: the ‘rudiments of commerce’ in the state of nature

Istvan Hont’s classic work on the theoretical links between the seventeenth-century natural jurists Hugo Grotius and Samuel Pufendorf and the eighteenth-century Scottish political economists remains a popular trope among intellectual and economic historians of various stamps. Despite this, a common criticism levelled at Hont remains his relative lack of engagement with the relationship between religion and economics in the early modern period. This paper challenges this aspect of Hont’s narrative by drawing attention to an alternative, albeit complementary, assessment of the natural jurisprudential heritage of eighteenth-century British political economy. Specifically, the article attempts to map on to Hont’s thesis the Christian Stoic interpretation of Grotius and Pufendorf which has gained greater currency in recent years. In doing so, the paper argues that Grotius and Pufendorf’s contributions to the ‘unsocial sociability’ debate do not necessarily lead directly to the Scottish school of political economists, as is commonly assumed. Instead, it contends that a reconsideration of Grotius and Pufendorf as neo-Stoic theorists, particularly via scrutiny of their respective adaptations of the traditional Stoic theory of oikeiosis, steers us towards the heart of the early English ‘clerical’ Enlightenment

Legionella pneumophila Secretes a Mitochondrial Carrier Protein during Infection

The Mitochondrial Carrier Family (MCF) is a signature group of integral membrane proteins that transport metabolites across the mitochondrial inner membrane in eukaryotes. MCF proteins are characterized by six transmembrane segments that assemble to form a highly-selective channel for metabolite transport. We discovered a novel MCF member, termed Legionella nucleotide carrier Protein (LncP), encoded in the genome of Legionella pneumophila, the causative agent of Legionnaire's disease. LncP was secreted via the bacterial Dot/Icm type IV secretion system into macrophages and assembled in the mitochondrial inner membrane. In a yeast cellular system, LncP induced a dominant-negative phenotype that was rescued by deleting an endogenous ATP carrier. Substrate transport studies on purified LncP reconstituted in liposomes revealed that it catalyzes unidirectional transport and exchange of ATP transport across membranes, thereby supporting a role for LncP as an ATP transporter. A hidden Markov model revealed further MCF proteins in the intracellular pathogens, Legionella longbeachae and Neorickettsia sennetsu, thereby challenging the notion that MCF proteins exist exclusively in eukaryotic organisms