Inflammation modulatory effect of perioperative high-dose statin in prevention of post-operative atrial fibrillation in patients undergoing coronary artery bypass grafting

Background: Atrial fibrillation (AF) is one of the most common complications after coronary artery bypass grafting (CABG), occurring in 20% to 40% of patients. Statins exert pleiotropic effects which are largely independent from their lipid-lowering properties.  The objective of this study was based on to affirm the evidence that perioperative statins have a significant role in preventing early postoperative AF in patients undergoing CABG.Methods: A prospective, randomized, cohort study of all consecutive patients who underwent primary isolated on pump CABG surgery was performed. Patients were divided into two groups -statin and non-statin groups - to examine the influence of statins on early postoperative prevention of AF.Results: In total, 127 patients who underwent isolated CABG were included in the study and were analysed. There were no significant differences in age, gender, history of cardiac infarction, concomitant diseases (hypertension, smoking, PPCI, hyperlipidaemia), cardiac functional grading (NYHA III-IV), electro- cardiograms, and preoperative medication. There were no significant differences in the average number of grafts where the left internal mammary artery was used as a bypass conduit, the surgical procedure or total cardiopulmonary bypass time, or aortic cross-clamping (ACC) time. In addition, there were no significant differences in the postoperative mechanical ventilation duration time, length of ICU stays or length of hospitalization between the two groups. The incidence of AF following CABG in the statin group was significantly lower than that in the non-statin group.Conclusions: Oral atorvastatin 40 mg/d, initiated at least 1 week before the scheduled CABG and continued in the early postoperative period, significantly decreases the risk of post-operative AF

Investigation of vacuum evaporated SnTe thin films for their structural, electrical and thermoelectric properties

Remarkable enhancement in figure-of-merit (ZT) value of p-type Tin Telluride (SnTe) thin films is reported in the present investigations. Under high vacuum conditions, all thin films deposited on the glass substrate by using thermal evaporation technique. Thickness of the thin films were kept 55 and 33 nm. Morphological features and the elemental composition of the thin film were investigated using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) technique respectively. High-resolution transmission electron microscopy (HRTEM) with selected area electron diffraction (SAED) pattern was used to investigate the microstructure of these thin films. For the identification of crystalline features, phase, and nano-crystallites size in all the thin films, the X-ray diffraction (XRD) technique had played a dominant role. The analysis of the XRD data results in a single-phase cubic structure. Atomic force microscopy (AFM) analysis revealed the 2D and 3D view of variable size grains formed on the glass substrate. Four probes method was used to determine the electrical conductivity of these thin films. Electrical measurements revealed the semi-metallic nature of the SnTe thin films. The thermoelectric measurement analysis revealed that the ZT of the thin films was found to be increased as the thickness of the film enhanced. The maximum value of ZT similar to 1.0 was obtained at room temperature for the film of thickness 55 nm

Investigation of vacuum evaporated SnTe thin films for their structural, electrical and thermoelectric properties

Remarkable enhancement in figure-of-merit (ZT) value of p-type Tin Telluride (SnTe) thin films is reported in the present investigations. Under high vacuum conditions, all thin films deposited on the glass substrate by using thermal evaporation technique. Thickness of the thin films were kept 55 and 33 nm. Morphological features and the elemental composition of the thin film were investigated using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) technique respectively. High-resolution transmission electron microscopy (HRTEM) with selected area electron diffraction (SAED) pattern was used to investigate the microstructure of these thin films. For the identification of crystalline features, phase, and nano-crystallites size in all the thin films, the X-ray diffraction (XRD) technique had played a dominant role. The analysis of the XRD data results in a single-phase cubic structure. Atomic force microscopy (AFM) analysis revealed the 2D and 3D view of variable size grains formed on the glass substrate. Four probes method was used to determine the electrical conductivity of these thin films. Electrical measurements revealed the semi-metallic nature of the SnTe thin films. The thermoelectric measurement analysis revealed that the ZT of the thin films was found to be increased as the thickness of the film enhanced. The maximum value of ZT∼1.0 was obtained at room temperature for the film of thickness 55 nm

Investigation of vacuum evaporated SnTe thin films for their structural, electrical and thermoelectric properties

740-749Remarkable enhancement in figure-of-merit (ZT) value of p-type Tin Telluride (SnTe) thin films is reported in the present investigations. Under high vacuum conditions, all thin films deposited on the glass substrate by using thermal evaporation technique. Thickness of the thin films were kept 55 and 33 nm. Morphological features and the elemental composition of the thin film were investigated using scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDS) technique respectively. High-resolution transmission electron microscopy (HRTEM) with selected area electron diffraction (SAED) pattern was used to investigate the microstructure of these thin films. For the identification of crystalline features, phase, and nano-crystallites size in all the thin films, the X-ray diffraction (XRD) technique had played a dominant role. The analysis of the XRD data results in a single-phase cubic structure. Atomic force microscopy (AFM) analysis revealed the 2D and 3D view of variable size grains formed on the glass substrate. Four probes method was used to determine the electrical conductivity of these thin films. Electrical measurements revealed the semi-metallic nature of the SnTe thin films. The thermoelectric measurement analysis revealed that the ZT of the thin films was found to be increased as the thickness of the film enhanced. The maximum value of ZT∼1.0 was obtained at room temperature for the film of thickness 55 nm

MUSiC : a model-unspecific search for new physics in proton-proton collisions at root s=13TeV

Results of the Model Unspecific Search in CMS (MUSiC), using proton-proton collision data recorded at the LHC at a centre-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 35.9 fb(-1), are presented. The MUSiC analysis searches for anomalies that could be signatures of physics beyond the standard model. The analysis is based on the comparison of observed data with the standard model prediction, as determined from simulation, in several hundred final states and multiple kinematic distributions. Events containing at least one electron or muon are classified based on their final state topology, and an automated search algorithm surveys the observed data for deviations from the prediction. The sensitivity of the search is validated using multiple methods. No significant deviations from the predictions have been observed. For a wide range of final state topologies, agreement is found between the data and the standard model simulation. This analysis complements dedicated search analyses by significantly expanding the range of final states covered using a model independent approach with the largest data set to date to probe phase space regions beyond the reach of previous general searches.Peer reviewe

Search for new particles in events with energetic jets and large missing transverse momentum in proton-proton collisions at root s=13 TeV

A search is presented for new particles produced at the LHC in proton-proton collisions at root s = 13 TeV, using events with energetic jets and large missing transverse momentum. The analysis is based on a data sample corresponding to an integrated luminosity of 101 fb(-1), collected in 2017-2018 with the CMS detector. Machine learning techniques are used to define separate categories for events with narrow jets from initial-state radiation and events with large-radius jets consistent with a hadronic decay of a W or Z boson. A statistical combination is made with an earlier search based on a data sample of 36 fb(-1), collected in 2016. No significant excess of events is observed with respect to the standard model background expectation determined from control samples in data. The results are interpreted in terms of limits on the branching fraction of an invisible decay of the Higgs boson, as well as constraints on simplified models of dark matter, on first-generation scalar leptoquarks decaying to quarks and neutrinos, and on models with large extra dimensions. Several of the new limits, specifically for spin-1 dark matter mediators, pseudoscalar mediators, colored mediators, and leptoquarks, are the most restrictive to date.Peer reviewe

Measurement of prompt open-charm production cross sections in proton-proton collisions at root s=13 TeV

The production cross sections for prompt open-charm mesons in proton-proton collisions at a center-of-mass energy of 13TeV are reported. The measurement is performed using a data sample collected by the CMS experiment corresponding to an integrated luminosity of 29 nb(-1). The differential production cross sections of the D*(+/-), D-+/-, and D-0 ((D) over bar (0)) mesons are presented in ranges of transverse momentum and pseudorapidity 4 < p(T) < 100 GeV and vertical bar eta vertical bar < 2.1, respectively. The results are compared to several theoretical calculations and to previous measurements.Peer reviewe

Combined searches for the production of supersymmetric top quark partners in proton-proton collisions at root s=13 TeV

A combination of searches for top squark pair production using proton-proton collision data at a center-of-mass energy of 13 TeV at the CERN LHC, corresponding to an integrated luminosity of 137 fb(-1) collected by the CMS experiment, is presented. Signatures with at least 2 jets and large missing transverse momentum are categorized into events with 0, 1, or 2 leptons. New results for regions of parameter space where the kinematical properties of top squark pair production and top quark pair production are very similar are presented. Depending on themodel, the combined result excludes a top squarkmass up to 1325 GeV for amassless neutralino, and a neutralinomass up to 700 GeV for a top squarkmass of 1150 GeV. Top squarks with masses from 145 to 295 GeV, for neutralino masses from 0 to 100 GeV, with a mass difference between the top squark and the neutralino in a window of 30 GeV around the mass of the top quark, are excluded for the first time with CMS data. The results of theses searches are also interpreted in an alternative signal model of dark matter production via a spin-0 mediator in association with a top quark pair. Upper limits are set on the cross section for mediator particle masses of up to 420 GeV

Probing effective field theory operators in the associated production of top quarks with a Z boson in multilepton final states at root s=13 TeV

Peer reviewe

Measurement of B-c(2S)(+) and B-c*(2S)(+) cross section ratios in proton-proton collisions at root s=13 TeV

Peer reviewe