Disseny de les instal·lacions d'una residència per a gent gran

L’objecte d’aquest projecte és realitzar el càlcul i disseny de les instal·lacions d’una residència per a la gent gran situada a Barbens. La residència en qüestió és un edifici ja existent i funcionant en l’actualitat, per al qual es farà el disseny d’algunes instal·lacions que avui en dia manquen, com és la instal·lació d’alguns elements contra incendis i la instal·lació d’aigua calenta sanitària mitjançant energia solar, i d’altres ja existents però que es considera que poden optimitzar-se i alhora adaptar-se a la normativa vigent degut a les continues inspeccions realitzades pels departaments d’Acció Social i Ciutadania i Treball, ja que la residència en qüestió és un centre privat però col·laborador amb la Generalitat de Catalunya.L’àmbit d’aplicació d’aquest projecte és el sector serveis, concretament els establiments destinats a allotjar de forma permanent o interrompuda a la gent gran, és a dir, tant centres de dia com residències

Application of Computer Simulation Modeling to Evaluate Business Continuity Plans

Business continuity plans (BCP) help organizations plan for and withstand the occurrence of unexpected events that interrupt the normal operation of business. Managers typically develop several alternate plans to minimize the business impact of unexpected events. The problem for decision makers is that comparative evaluation of BCP is typically done using subjective judgments. This research uses a case study approach focusing on a single organization and a single business continuity application to propose the use of computer simulation as a tool for managers to identify and evaluate different BCP prior to committing resources. In the context of an insurance firm, a specific plan was evaluated using simulation methods. A simulation model was used to model the operational aspects of the call center in an insurance company. After the model was validated, it was used to answer questions about what-if scenarios. Results suggest that scenario analysis using simulated model enables managers to ask useful questions that can help evaluate the plan. Managers at the insurance company used the simulation model to determine the level of service required and evaluate business continuity strategies to achieve it

3D Segmentation Method for Natural Environments based on a Geometric-Featured Voxel Map

This work proposes a new segmentation algorithm for three-dimensional dense point clouds and has been specially designed for natural environments where the ground is unstructured and may include big slopes, non-flat areas and isolated areas. This technique is based on a Geometric-Featured Voxel map (GFV) where the scene is discretized in constant size cubes or voxels which are classified in flat surface, linear or tubular structures and scattered or undefined shapes, usually corresponding to vegetation. Since this is not a point-based technique the computational cost is significantly reduced, hence it may be compatible with Real-Time applications. The ground is extracted in order to obtain more accurate results in the posterior segmentation process. The scene is split into objects and a second segmentation in regions inside each object is performed based on the voxel’s geometric class. The work here evaluates the proposed algorithm in various versions and several voxel sizes and compares the results with other methods from the literature. For the segmentation evaluation the algorithms are tested on several differently challenging hand-labeled data sets using two metrics, one of which is novel.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Evaluación de caldos minerales y extractos vegetales para el control de gusano cogollero (Spodoptera frugiperda) en el cultivo de maíz (Zea mays L.) municipio de Garzón, Huila

Según Troya Garcia, 2011 “El gusano cogollero del maíz Spodoptera frugiperda, es una plaga cuyo control se torna cada vez más difícil, las condiciones climáticas cada vez son más calurosas hacen que esta plaga acelere su ciclo de vida y el control sea más costoso. La larva normalmente busca estar en la parte húmeda de la planta y penetra a través del cogollo para quedarse allí, para buscar de esta forma una mejor condición para seguir viviendo. Es por esto que su control se torna difícil. El uso de insecticidas químicos para el control de esta especie puede ocasionar diversos daños al medioambiente o que pueden afectar económicamente al productor”, por lo que es de gran interés la búsqueda de agentes alternativos de control, para esto es necesario el uso de plantas que pueden sintetizar sustancias biocidas y el caldo mineral que actúa en el equilibrio nutricional de la planta (Restrepo Rivera, J. 2007). Las ventajas del uso de bio insumos frente a los insecticidas de síntesis química son muchas. Como por ejemplo el control de un insecto y al mismo tiempo este nutriendo a la planta, pero también cuide el medio ambiente como suelo, aire, agua asimismo la fauna, la macrofauna y la micro fauna, de la misma manera que se respeta al medio ambiente, el hombre es un factor importante en la no utilización de agroquímicos. Es por este el motivo que se evaluaran tres tratamientos el T1 caldo ceniza el T2 extracto de ajo, T3 extracto de ají y el T4 es el testigo que no se le realiza ningún control, es de esta manera como se evaluara estadísticamente el control de Spodoptera frugiperda en el cultivo de maíz ICA V-354 en la finca Casa loma de la vereda bajo Sartenejo del municipio de Garzón Huila.According to Troya Garcia, 2011 "The corn earworm Spodoptera frugiperda is a pest whose control is becoming increasingly difficult, the increasingly hot weather conditions make this pest accelerate its life cycle and control is more costly. The larva normally seeks to be in the humid part of the plant and penetrates through the bud to stay there, thus looking for a better condition to continue living. This is why its control becomes difficult. The use of chemical insecticides for the control of this species can cause various damages to the environment or can economically affect the producer", so it is of great interest to search for alternative control agents, for which it is necessary to use plants that can synthesize biocidal substances and the mineral broth that acts in the nutritional balance of the plant (Restrepo Rivera, J. 2007). There are many advantages to using bio-inputs over chemical synthesis insecticides. For example, it controls the insect and at the same time nourishes the plant, and also takes care of its environment such as the soil, air, water, fauna, macrofauna and microfauna that surrounds them. In the same way that the environment is respected, man is an important factor in the non-use of agrochemicals. This is the reason that three treatments will be evaluated: T1 ash broth, T2 garlic extract, T3 chili extract and T4 is the control without any control. This is how the control of Spodoptera frugiperda will be statistically evaluated in the corn crop ICA V-354 in the Casa Loma de la Vereda Bajo Sartenejo farm in the municipality of Garzón Huila

ZnO Nanostructures Synthesized by Chemical Solutions

Nanomaterials have been synthesized using several different techniques. Some of these techniques are sophisticated, expensive and need certain training before use. However, there are other highly efficient methods for preparing nanomaterials that are easy to work with and require no specialized equipment, making them relatively inexpensive routes for synthesis. The least expensive routes are those that are classified as solution‐based techniques such as colloidal, sol‐gel and microwave‐assisted synthesis. The focus of this chapter is on a general description of each technique with recent advances in synthesis, doping processes and applications. Specifically, these processes are discussed in connection with the synthesis of ZnO compounds and its related nanomaterials

The role of heart rate on the associations between body composition and heart rate variability in children with overweight/obesity : the ActiveBrains project

Background: Heart rate variability (HRV) is negatively associated with body mass index and adiposity in several populations. However, less information is available about this association in children with overweight and obesity, especially severe/morbid obesity, taking into consideration the dependence of HRV on heart rate (HR). Objectives: (1) to examine associations between body composition measures and HRV, (2) to study differences in HRV between children with overweight and severe/morbid obesity; and (3) to test whether relationships and differences tested in objectives 1 and 2, respectively are explained by the dependency of HRV on HR. Methods: A total of 107 children with overweight/obesity (58% boys, 10.03 +/- 1.13 years) participated in this study. Body composition measures were evaluated by Dual-energy X-ray absorptiometry (DXA). HRV parameters were measured with Polar RS800CXR (R). Results: Body composition measures were negatively associated with HRV indicators of parasympathetic activity (beta values ranging from -0.207 to -0.307, all p 0.05). Conclusion: All associations between adiposity/obesity and HRV could be explained by HR, suggesting a key confounding role of HR in HRV studies in children with weight disturbances

Floppy closing door epiglottis treated successfully with an mhealth application based on myofunctional therapy: a case report

We introduce the first case reported to date of a floppy closing door epiglottis in an OSA (obstructive sleep apnea) patient treated successfully with an Mhealth smartphone application based on myofunctional therapy

Gene-environment interaction analysis of redox-related metals and genetic variants with plasma metabolic patterns in a general population from Spain: The Hortega Study

Background: Limited studies have evaluated the joint influence of redox-related metals and genetic variation on metabolic pathways. We analyzed the association of 11 metals with metabolic patterns, and the interacting role of candidate genetic variants, in 1145 participants from the Hortega Study, a population-based sample from Spain. Methods: Urine antimony (Sb), arsenic, barium (Ba), cadmium (Cd), chromium (Cr), cobalt (Co), molybdenum (Mo) and vanadium (V), and plasma copper (Cu), selenium (Se) and zinc (Zn) were measured by ICP-MS and AAS, respectively. We summarized 54 plasma metabolites, measured with targeted NMR, by estimating metabolic principal components (mPC). Redox-related SNPs (N = 291) were measured by oligo-ligation assay. Results: In our study, the association with metabolic principal component (mPC) 1 (reflecting non-essential and essential amino acids, including branched chain, and bacterial co-metabolism versus fatty acids and VLDL subclasses) was positive for Se and Zn, but inverse for Cu, arsenobetaine-corrected arsenic (As) and Sb. The association with mPC2 (reflecting essential amino acids, including aromatic, and bacterial co-metabolism) was inverse for Se, Zn and Cd. The association with mPC3 (reflecting LDL subclasses) was positive for Cu, Se and Zn, but inverse for Co. The association for mPC4 (reflecting HDL subclasses) was positive for Sb, but inverse for plasma Zn. These associations were mainly driven by Cu and Sb for mPC1; Se, Zn and Cd for mPC2; Co, Se and Zn for mPC3; and Zn for mPC4. The most SNP-metal interacting genes were NOX1, GSR, GCLC, AGT and REN. Co and Zn showed the highest number of interactions with genetic variants associated to enriched endocrine, cardiovascular and neurological pathways. Conclusions: Exposures to Co, Cu, Se, Zn, As, Cd and Sb were associated with several metabolic patterns involved in chronic disease. Carriers of redox-related variants may have differential susceptibility to metabolic alterations associated to excessive exposure to metals.This work was supported by the Strategic Action for Research in Health sciences [CP12/03080, PI15/00071, PI10/0082, PI13/01848, PI14/00874, PI16/01402, PI21/00506 and PI11/00726], CIBER Fisio patología Obesidad y Nutrición (CIBEROBN) (CIBER-02-08-2009, CB06/03 and CB12/03/30,016), the State Agency for Research (PID2019-108973RB- C21 and C22), the Valencia Government (GRUPOS 03/101; PROMETEO/2009/029 and ACOMP/2013/039, IDI FEDER/2021/072 and GRISOLIAP/2021/119), the Castilla-Leon Government (GRS/279/A/08) and European Network of Excellence Ingenious Hypercare (EPSS-037093) from the European Commission. The Strategic Action for Research in Health sciences, CIBERDEM and CIBEROBN are initiatives from Carlos III Health Institute Madrid and cofunded with European Funds for Regional Development (FEDER). The State Agency for Research and Carlos III Health Institute belong to the Spanish Ministry of Science and Innovation. ADR received the support of a fellowship from “la Caixa” Foundation (ID 100010434) (fellowship code “LCF/BQ/DR19/11740016”). MGP received the support of a fellowship from “la Caixa” Foundation (ID 100010434, fellowship code LCFLCF/BQ/DI18/11660001). The funding bodies had no role in the design of the study and collection, analysis, and interpretation of data and in writing the manuscript.S

Targeted gold-coated iron oxide nanoparticles for CD163 detection in atherosclerosis by MRI

CD163 is a membrane receptor expressed by macrophage lineage. Studies performed in atherosclerosis have shown that CD163 expression is increased at inflammatory sites, pointing at the presence of intraplaque hemorrhagic sites or asymptomatic plaques. Hence, imaging of CD163 expressing macrophages is an interesting strategy in order to detect atherosclerotic plaques. We have prepared a targeted probe based on gold-coated iron oxide nanoparticles vectorized with an anti-CD163 antibody for the specific detection of CD163 by MRI. Firstly, the specificity of the targeted probe was validated in vitro by incubation of the probe with CD163(+) or (−) macrophages. The probe was able to selectively detect CD163(+) macrophages both in human and murine cells. Subsequently, the targeted probe was injected in 16 weeks old apoE deficient mice developing atherosclerotic lesions and the pararenal abdominal aorta was imaged by MRI. The accumulation of probe in the site of interest increased over time and the signal intensity decreased significantly 48 hours after the injection. Hence, we have developed a highly sensitive targeted probe capable of detecting CD163-expressing macrophages that could provide useful information about the state of the atheromatous lesionsThis work was funded by Spanish Government through a Plan Nacional (CTQ2011–27268), FEDER funds through the Fondo de Investigación Sanitaria (PI10/00072, PI13/00051, PI13/00395, PI13/00802, PI14/00883 and PI14/00386), CIBERDEM group, RETICS RD12/0042/0038, Programa Miguel Servet (CP10/00479) and cvREMOD CENIT project (CEN-20091044), the Basque Government through Etortek 2011 (IE11–301), and Fundacion Lilly, Spanish Society of Atherosclerosis, Spanish Society of Nephrology and Fundacion Renal Iñigo Alvarez de Toled