56 research outputs found
Purchase of Service Contracting Versus Government Service Delivery: The Views of State Human Service Administrators
Purchase of service contracting (POSC) as a mode of human service delivery is based largely on untested normative grounds. This article presents the results of a national study comparing the views of state human service administrators on the relative merits of POSC versus government service delivery in four issue areas: (1) service costs, (2) service quality, (3) bureaucracy and red tape, and (4) effect on government employees. The study results provide some support for POSC in three of the four issues areas. The study finds that geography plays no role in the views of state human service administrators, but that program/service type does
Purchase of Service Contracting In the 1990s: Have Expectations Been Met?
Privatization and purchase of service contracting (POSC) are generally considered to be two of the most important factors that have helped shape the human service system during the 1970s and 1980s (Gilbert, 1983, 1986; Kammerman, 1983; Demone and Gibelman, 1984, 1989; Weddell, 1986; Kettner and Martin, 1985; Termell, 1987; Rein, 1989). Therefore, as we enter the decade of the 1990s, it would seem both appropriate and worthwhile to reflect on the original expectations for privatization and POSC and to assess the extent to which these expectations have been realized
Factors Affecting Competition in State Contracting for Human Services
Competition has long been recognized as a necessary ingredient of our economic system. Competition, it is argued, is needed to combat the negative effects of monopoly
Forensic, legal, and clinical aspects of deaths associated with implanted cardiac devices
As the population ages, the prevalence of heart failure and individuals wearing an
implanted cardiac device is increasing. The combination of different underlying
pathophysiologies and (the combination of) implanted cardiac devices can
become a challenge with regard to the determination of cause and manner of
death in such individuals. Additionally, heart disease is frequently associated with
mental disease, ranging from anxiety and depression to suicidality and suicide
(attempts). At the same time, the correct diagnosis of cause and manner of death
is the basis for quality assurance, further therapeutic advances, legal safety, and
suicide prevention. By that, an interdisciplinary field between legal medicine,
clinicians, and law enforcement opens up. In this field, the different participants
can simultaneously benefit from and need each other. For example, legal medicine
experts need investigatory results and clinical expertise for the interpretation of
readout data of implanted cardiac devices in order to correctly determine the
cause of death. A correctly determined cause of death can assist law enforcement
and help clinicians to further improve various therapeutic approaches based on
correct mortality data collection. In addition, it is the basis for identification of
suicides of device carriers, allowing psychological and psychiatric experts to
better understand the burden of mental disease in this particular cohort. Against
this interdisciplinary background, this manuscript summarizes information about
psychiatric comorbidities and suicidality while being on a device. Thereby, basic
information on complications and malfunctions of implanted cardiac devices,
device-associated deaths with particular emphasis on device manipulation is
displayed as basic information needed for correct determination of the cause
of death. Also, legal and ethical issues in this field are outlined. The final result is
a proposal of an interdisciplinary assessment workflow for a conjoint approach
to improve the diagnosis of deaths associated with implanted cardiac devices. It
will allow for a differentiation between an individual who died with or due to the
device
Forensic, legal, and clinical aspects of deaths associated with implanted cardiac devices
As the population ages, the prevalence of heart failure and individuals wearing an implanted cardiac device is increasing. The combination of different underlying pathophysiologies and (the combination of) implanted cardiac devices can become a challenge with regard to the determination of cause and manner of death in such individuals. Additionally, heart disease is frequently associated with mental disease, ranging from anxiety and depression to suicidality and suicide (attempts). At the same time, the correct diagnosis of cause and manner of death is the basis for quality assurance, further therapeutic advances, legal safety, and suicide prevention. By that, an interdisciplinary field between legal medicine, clinicians, and law enforcement opens up. In this field, the different participants can simultaneously benefit from and need each other. For example, legal medicine experts need investigatory results and clinical expertise for the interpretation of readout data of implanted cardiac devices in order to correctly determine the cause of death. A correctly determined cause of death can assist law enforcement and help clinicians to further improve various therapeutic approaches based on correct mortality data collection. In addition, it is the basis for identification of suicides of device carriers, allowing psychological and psychiatric experts to better understand the burden of mental disease in this particular cohort. Against this interdisciplinary background, this manuscript summarizes information about psychiatric comorbidities and suicidality while being on a device. Thereby, basic information on complications and malfunctions of implanted cardiac devices, device-associated deaths with particular emphasis on device manipulation is displayed as basic information needed for correct determination of the cause of death. Also, legal and ethical issues in this field are outlined. The final result is a proposal of an interdisciplinary assessment workflow for a conjoint approach to improve the diagnosis of deaths associated with implanted cardiac devices. It will allow for a differentiation between an individual who died with or due to the device
The internal structure of Paleoalpine thrusts of the Western Carpathians: A case study from the KriĆŸnĂĄ thrust system
Meeting Report from the Second 'Minimum Information for Biological and Biomedical Investigations (MIBBI) workshop
Face-to-face meetings play a central role in the birth and maturation of communities. Intensive workshops filled with presentations, discussions and working group meetings have always been at the heart of the activities of the Genomic Standards Consortium (GSC). Such work-driven meetings are a key way in which the GSC fulfils its mission. Similarly, meeting reports provide a key mechanism for preserving and disseminating the consensus built at such meetings as they describe the range of speakers and participants present, topics covered and key outcomes and priorities agreed upon by the community.This issue contains a total of nine meeting reports, from workshops held between April and October 2010 that are presented to the reader to provide a broad overview of ongoing GSC activities and initiatives
STRENDA DB : enabling the validation and sharing of enzyme kinetics data
Standards for reporting enzymology data (STRENDA) DB is a validation and storage system for enzyme function data that incorporates the STRENDA Guidelines. It provides authors who are preparing a manuscript with a userâfriendly, webâbased service that checks automatically enzymology data sets entered in the submission form that they are complete and valid before they are submitted as part of a publication to a journal
Subsequent Event Risk in Individuals with Established Coronary Heart Disease:Design and Rationale of the GENIUS-CHD Consortium
BACKGROUND:
The "GENetIcs of sUbSequent Coronary Heart Disease" (GENIUS-CHD) consortium was established to facilitate discovery and validation of genetic variants and biomarkers for risk of subsequent CHD events, in individuals with established CHD.
METHODS:
The consortium currently includes 57 studies from 18 countries, recruiting 185,614 participants with either acute coronary syndrome, stable CHD or a mixture of both at baseline. All studies collected biological samples and followed-up study participants prospectively for subsequent events.
RESULTS:
Enrollment into the individual studies took place between 1985 to present day with duration of follow up ranging from 9 months to 15 years. Within each study, participants with CHD are predominantly of self-reported European descent (38%-100%), mostly male (44%-91%) with mean ages at recruitment ranging from 40 to 75 years. Initial feasibility analyses, using a federated analysis approach, yielded expected associations between age (HR 1.15 95% CI 1.14-1.16) per 5-year increase, male sex (HR 1.17, 95% CI 1.13-1.21) and smoking (HR 1.43, 95% CI 1.35-1.51) with risk of subsequent CHD death or myocardial infarction, and differing associations with other individual and composite cardiovascular endpoints.
CONCLUSIONS:
GENIUS-CHD is a global collaboration seeking to elucidate genetic and non-genetic determinants of subsequent event risk in individuals with established CHD, in order to improve residual risk prediction and identify novel drug targets for secondary prevention. Initial analyses demonstrate the feasibility and reliability of a federated analysis approach. The consortium now plans to initiate and test novel hypotheses as well as supporting replication and validation analyses for other investigators
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