Estudio comparativo de los pimentones "Jarande", "Agridulce" y "Bola" de Extremadura, "Papri-Queen" de Perú y "Bola" de Murcia en embutidos y su efecto sobre el consumo

O presente trabalho faz um estudo comparativo dos pimentos "Jaranda", "Agridulce" e "Bola" de Extremadura, "Papí-queen" de Peú e "Bola" de Murcia em enchidos e o seu efeito sobre o consumo. O pimentão, um dos corantes naturais mais utilizados em Espanha, é de grande importância para a Extremadura que, com 3.179 toneladas produzidas em 2012, representa 60% do total nacional. O "Pimentón de la Vera" é o principal pimentão espanhol utilizado na produção de enchidos, deüdo à sua conservação e prolongamento da vida útil. Neste trabalho utilizaram-se métodos fisico-químicos e sensoriais para compro\Er o eÍeito do pimentão sobre a qualidade de diferentes lotes de enchidos. A análise sensorial Íoi realizada atrarcs de um painel de provadores que, para além das característlcas mais importantes, avaliou ainda a aceitabilidade dos enchi dos. Os lotes de enchidos com pimentão de "La Vera" ('Agridulce", "Bola" e "Jaranda") foram os que demostraram menorgrau de oxidação e, portanto, com menor grau de rancidez, em comparação com os lotes que incorporaram as outras lariedades. Esta situação foi também confirmada pelo painel de provadores que apreciaram o efeito antioxidante do pimentão de "La Vera" nos lotes de enchidos assim como a preservação dos atributos de qualidade; Abstract: GoMPARATIVE STUDY OF DTFFERENT PAPRTKA FROM D(TREMADURA ("JARANDA", "AGRIDULCE',AND'BOLA') FROM PERU ("PAPR|-QUEEN") AND FROM MURCIA ("BOLA',) lN SAUSAGE PRODUCTION AND ITS EFFECT ON CONSUMPTION This work makes a comparative study of paprika "Jaranda", 'Agridulce" and "Bola" fom Extremadura and "Papri-queen" oÍ Peru and "Bola" fom Murcia in sausages production and their effect on consumption. The paprika, one of the most used natural food colorants in Spain, is of great importance for the Extremadura region, which accounted for 60% (3.179 metric tons) of the Spanish production in 2012. The paprika 'La Vera' is the main Spanish used in dry-cured sausages production, due to its role in preservation and also helping to extend their shelf life. ln this research, physicochemical and sensory methods were used to check the effect of different paprika varieties on quality of difierent batches of dry-cured sausages. Sensory analysis was performed by a panel oÍ tasters to test different sausages types in order to evaluate the sensory aspects and the acceptability ofsausages. The batches of sausage made with La Vera paprika ("Jaranda", 'Agridulce" and "Bola") demonstrated a lower degree of oxidation and therefore a smaller degree of rancidity, as compared with the batches that have incorporated the other paprika varieties. This results was also confirmed by the tasters panel, who appreciated the antioxidant efiect oÍ La Vera paprika to preserve the quality attributes of dry-cured sausages

Multivariate geostatistical analysis of stable isotopes in Portuguese varietal extra virgin olive oils

Stable isotope contents of carbon, hydrogen and oxygen are known to reflect the geo-climatic conditions under which olives grown. This study aims to unravel the correlation between some of the main geographic variables and the isotopic composition of different Portuguese varietal extra virgin olive oil (EVOO) samples. Thus, the isotopic composition (δ13C, δ18O and δ2H) of 38 EVOO samples from 11 olive varieties from 2 Portuguese regions (Alentejo and Trás-os-Montes) was studied using an elemental analyzer coupled to an isotope ratio mass spectrometry. Multivariate analysis indicated that bulk δ13C, δ2H and δ18O values were enough to significantly (P < 0.05) predict altitude, latitude, longitude, temperature, rainfall, and sea distance. This work showed that the assessment of EVOO isotopic composition give information not only on the geographic origin, but also on the environmental conditions. To the best of our knowledge, this is the first report on bulk isotopic composition of Portuguese EVOOs.This work was funded by European Regional Development Fund (FEDER) and National Funds through Foundation for Science and Technology (FCT) under Project “Por3O - Portuguese Olive Oil Omics for traceability and authenticity - PTDC/AGRPRO/2003/2014, and by National Funds through FCT - Foundation for Science and Technology under the Projects UIDB/05183/2020 and UID/AGR/00690/2019. Pedro N. Jiménez-Morillo is acknowledged for statistical assistance.info:eu-repo/semantics/publishedVersio

Impacto de la pandemia por SARS-CoV2 en la actividad asistencial y en la salud del personal de hemodiálisis en las diferentes oleadas

Introducción: Además de las consecuencias del SARS-CoV-2 sobre los pacientes renales infectados, mantener la actividad durante la pandemia ha supuesto todo un reto dada la escasez de personal por las ausencias por enfermedad. Objetivo: Analizar la incidencia de contagios por Covid-19 entre los profesionales de hemodiálisis, sus características y su repercusión en bajas laborales en las diferentes oleadas. Material y Método: Estudio observacional longitudinal desde el 3/03/2020 hasta el 23/04/2022 (776 días) en una media de 406 profesionales sanitarios y no sanitarios de 18 unidades de diálisis y dos unidades administrativas de apoyo de la Fundación Renal Iñigo Álvarez de Toledo. La recogida de datos se realizó a través de la comunicación de las distintas supervisoras al departamento de recursos humanos. Resultados: 179 profesionales de un promedio de 406 (44,1%) se infectaron en el periodo de estudio, siendo el 52% enfermeras, 25% auxiliares, 11% nefrólogos y 12% otros profesionales. Un 40,2% de los casos presentaron síntomas. Un total de 160 contagiados estuvo ausente por enfermedad (89,3%), con una media de 15,9±14,3 días. En el 71,6% se detectó un contacto estrecho (todos fuera de las unidades) y esta identificación de contactos fue creciente según avanzaban las oleadas, pasando de un 6,7% en la 1ª ola a un 40% en la 6ª ola (p=0,016). Conclusiones: La sintomatología ha sido leve, al menos de dos semanas de ausencia por enfermedad; los contactos estrechos detectados han sido fundamentalmente comunitarios, sin registrarse contagios a través de los pacientes renales en las unidades

Physicochemical and nutritional characterization of brebas for fresh consumption from nine fig varieties (Ficus carica L.) grown in Extremadura (Spain)

Se determinaron las características de calidad de brevas para consumo en fresco de nueve variedades de higos en diferentes etapas de maduración comercial. Los parámetros fisicoquímicos y nutricionales se analizaron para la piel y la carne, y los hallazgos se compararon entre las variedades y las etapas de maduración. Los resultados revelaron que los componentes principales de nutrientes en brebas son los azúcares, como la glucosa y la fructosa, y los elementos minerales, incluidos K, Ca, P y Mg. La mayoría de los nutrientes evaluados son elementos importantes que contribuyen a la calidad comercial de brebas. Las variedades “Pavo marrón” y “Banane” mostraron el mayor peso y ancho. Las concentraciones de azúcares monoméricos estudiados fueron más altas en carne que en piel, y las variedades "Cuello Dama Blanco" y "Colar Elche" mostraron el mayor contenido de estos azúcares. La etapa de maduración temprana, coincidiendo con un rápido aumento en el tamaño de la fruta, también se asoció con un mayor contenido de fibra y proteína, TA y firmeza para las variedades "Banane", "Brown Turkey" y "Blanca Bétera". Por el contrario, la etapa de maduración posterior se relacionó con un aumento significativo de TSS, MI y intensidad de color. Finalmente, no se observaron cambios claros en las concentraciones de ácidos orgánicos entre las diferentes variedades y las etapas de maduración comercial.The quality characteristics of brebas for fresh consumption from nine fig varieties at different commercial ripening stages were determined. Physicochemical and nutritional parameters were analyzed for both skin and flesh, and the findings were compared among varieties and ripening stages. The results revealed that the major nutrient components in brebas are sugars, such as glucose and fructose, and mineral elements, including K, Ca, P, and Mg. Most nutrients evaluated are important elements that contribute to the commercial quality of brebas. “Brown Turkey” and “Banane” varieties showed the highest weight and width. The concentrations of the monomer sugars studied were higher in flesh than skin, and the “Cuello Dama Blanco” and “Colar Elche” varieties showed the highest content of these sugars. The early ripening stage, coinciding with a fast increase in fruit size, was also associated with a higher fiber and protein contents, TA, and firmness for “Banane,” “Brown Turkey,” and “Blanca Bétera” varieties. Conversely, the later ripening stage was related to a significant increase of TSS, MI, and color intensity. Finally, no clear changes in the concentrations of organic acids were observed between different varieties and commercial ripening stages.• Ministerio de Economía y Competitividad. Proyecto RTA 2010-00123 • Junta de Extremadura. Proyecto GR15112 • Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA). Beca para Cristina Pereira JiménezpeerReviewe

Fruit composition profile of pepper, tomato and eggplant varieties grown under uniform conditions

[EN] The study of the diversity within and between major Solanaceae crops (pepper, tomato, eggplant) is of interest for the selection and development of balanced diets. We have measured thirty-six major fruit composition traits, encompassing sugars, organic acids, antioxidants and minerals, in a set of 10 accessions per crop for pepper, tomato and eggplant, grown under the same cultivation conditions. The aim was to evaluate the diversity within species and to provide an accurate comparison of fruit composition among species by reducing to a minimum the environmental effect. Pepper, tomato and eggplant had a clearly distinct composition profile. Pepper showed the highest average content in total sugars and organic acids. Fructose and glucose were the major sugar compounds in the three species, although in pepper and tomato sucrose was present only in trace amounts. Citric acid was the major organic acid in pepper and tomato, while in eggplant it was malic acid. Pepper and eggplant had the highest total antioxidant activity. Vitamin C content was much higher in pepper than in tomato and eggplant, while eggplant accumulated high concentrations of chlorogenic acid. Furthermore, eggplant was the species with higher content in most minerals, particularly for K, Mg and Cu, while pepper was the richest in Fe. Due to their complementary nutritional profiles, a combined regular consumption of the three vegetables would supply more than 20% of the Dietary Reference Intake of several of the analysed phytochemicals. The large diversity within each species is of interest for selecting varieties with better nutritional and organoleptic profiles, as well as for breeding new cultivars.This work has been funded by the European Union's Horizon 2020 Research and Innovation Programme under grant agreement No. 677379 (Linking genetic resources, genomes and phenotypes of Sola-naceous crops; G2PSOL) . Elena RosaMartinez is grateful to the Spanish Ministerio de Economia, Industria y Competitividad for a pre-doctoral grant (BES2016077482)Rosa-Martínez, E.; García-Martínez, MD.; Adalid-Martinez, AM.; Pereira-Días, L.; Casanova-Calancha, C.; Soler-Calabuig, E.; Figás-Moreno, MDR.... (2021). Fruit composition profile of pepper, tomato and eggplant varieties grown under uniform conditions. Food Research International. 147:1-13. https://doi.org/10.1016/j.foodres.2021.110531S11314

Modeling the Behavior of an Underwater Acoustic Relative Positioning System Based on Complementary Set of Sequences

The great variability usually found in underwater media makes modeling a challenging task, but helpful for better understanding or predicting the performance of future deployed systems. In this work, an underwater acoustic propagation model is presented. This model obtains the multipath structure by means of the ray tracing technique. Using this model, the behavior of a relative positioning system is presented. One of the main advantages of relative positioning systems is that only the distances between all the buoys are needed to obtain their positions. In order to obtain the distances, the propagation times of acoustic signals coded by Complementary Set of Sequences (CSS) are used. In this case, the arrival instants are obtained by means of correlation processes. The distances are then used to obtain the position of the buoys by means of the Multidimensional Scaling Technique (MDS). As an early example of an application using this relative positioning system, a tracking of the position of the buoys at different times is performed. With this tracking, the surface current of a particular region could be studied. The performance of the system is evaluated in terms of the distance from the real position to the estimated one

Innovative computerized dystrophin quantification method based on spectral confocal microscopy

© 2023 by the authorsSeveral clinical trials are working on drug development for Duchenne and Becker muscular dystrophy (DMD and BMD) treatment, and, since the expected increase in dystrophin is relatively subtle, high-sensitivity quantification methods are necessary. There is also a need to quantify dystrophin to reach a definitive diagnosis in individuals with mild BMD, and in female carriers. We developed a method for the quantification of dystrophin in DMD and BMD patients using spectral confocal microscopy. It offers the possibility to capture the whole emission spectrum for any antibody, ensuring the selection of the emission peak and allowing the detection of fluorescent emissions of very low intensities. Fluorescence was evaluated first on manually selected regions of interest (ROIs), proving the usefulness of the methodology. Later, ROI selection was automated to make it operator-independent. The proposed methodology correctly classified patients according to their diagnosis, detected even minimal traces of dystrophin, and the results obtained automatically were statistically comparable to the manual ones. Thus, spectral imaging could be implemented to measure dystrophin expression and it could pave the way for detailed analysis of how its expression relates to the clinical course. Studies could be further expanded to better understand the expression of dystrophin-associated protein complexes (DAPCs).This research was partially founded by “Somriures Valents” (private grant).Peer ReviewedPostprint (published version

Immune and spermatogenesis-related loci are involved in the development of extreme patterns of male infertility

We conducted a genome-wide association study in a large population of infertile men due to unexplained spermatogenic failure (SPGF). More than seven million genetic variants were analysed in 1,274 SPGF cases and 1,951 unaffected controls from two independent European cohorts. Two genomic regions were associated with the most severe histological pattern of SPGF, defined by Sertoli cell-only (SCO) phenotype, namely the MHC class II gene HLA-DRB1 (rs1136759, P = 1.32E-08, OR = 1.80) and an upstream locus of VRK1 (rs115054029, P = 4.24E-08, OR = 3.14), which encodes a protein kinase involved in the regulation of spermatogenesis. The SCO-associated rs1136759 allele (G) determines a serine in the position 13 of the HLA-DR beta 1 molecule located in the antigen-binding pocket. Overall, our data support the notion of unexplained SPGF as a complex trait influenced by common variation in the genome, with the SCO phenotype likely representing an immune-mediated condition. A GWAS in a large case-control cohort of European ancestry identifies two genomic regions, the MHC class II gene HLA-DRB1 and an upstream locus of VRK1, that are associated with the most severe phenotype of spermatogenic failure

A consensus statement for trauma surgery capacity building in Latin America

Background Trauma is a significant public health problem in Latin America (LA), contributing to substantial death and disability in the region. Several LA countries have implemented trauma registries and injury surveillance systems. However, the region lacks an integrated trauma system. The consensus conference’s goal was to integrate existing LA trauma data collection efforts into a regional trauma program and encourage the use of the data to inform health policy. Methods We created a consensus group of 25 experts in trauma and emergency care with previous data collection and injury surveillance experience in the LA. region. Experts participated in a consensus conference to discuss the state of trauma data collection in LA. We utilized the Delphi method to build consensus around strategic steps for trauma data management in the region. Consensus was defined as the agreement of ≥ 70% among the expert panel. Results The consensus conference determined that action was necessary from academic bodies, scientific societies, and ministries of health to encourage a culture of collection and use of health data in trauma. The panel developed a set of recommendations for these groups to encourage the development and use of robust trauma information systems in LA. Consensus was achieved in one Delphi round. Conclusions The expert group successfully reached a consensus on recommendations to key stakeholders in trauma information systems in LA. These recommendations may be used to encourage capacity building in trauma research and trauma health policy in the region

Thermodynamics of mixtures with strongly negative deviations from Raoult's law. XV. Permittivities and refractive indices for 1-alkanol + n-hexylamine systems at (293.15–303.15) K. Application of the Kirkwood-Fröhlich model

Relative permittivities at 1 MHz, , and refractive indices at the sodium D-line, , are reported at 0.1 MPa and at (293.15–303.15) K for the binary systems 1-alkanol + n-hexylamine (HxA). Also, their corresponding excess functions are calculated and correlated. Positive values of the excess permittivities, , are encountered for the methanol system, whereas the remaining mixtures show negative values. This reveals that interactions between unlike molecules contribute positively to . This contribution is dominant for the methanol mixture, while those arising from the breaking of interactions between like molecules are prevalent for the remaining mixtures. At (volume fraction) = 0.5, changes in the order: methanol > 1-propanol > 1-butanol > 1-pentanol < 1-heptanol. Similar variation with the chain length of the 1-alkanol is observed for mixtures such as 1-alkanol + heptane, or + cyclohexylamine, and can be explained in terms of the lower and weaker self-association of longer 1-alkanols. The effect of the replacement of HxA by cyclohexylamine, or by aniline, is also shown. Calculations on molar refractions indicate that dispersive interactions in the systems under study increase with the length of the 1-alkanol. The mixtures are studied by means of the application of the Kirkwood-Fröhlich model, and the Kirkwood correlation factors, including the corresponding excess values, are reported.Ministerio de Educación, Cultura y Deporte for the grants FPU14/04104 and FPU15/05456 respectively. The authors gratefully acknowledge the financial support received from the Consejería de Educación y Cultura of Junta de Castilla y León, under Project BU034U16