411 research outputs found

    Deployment and evaluation of a usage based collaborative filtering recommendation system with blacklists

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    Social web sites, like Palco Principal (PP), have considerably sizeddatabases with the most varied types of information from user subscriptioninformation to user interactions. All that information is susceptible of beingprocessed using data mining algorithms in order to extract knowledge relevantfor the business. This document describes the implementation and evaluation ofa system that uses data mining techniques, and that has been developed with thespecific intent of generating recommendations, namely musicrecommendations, to users of the PP web site. The implemented system usescollaborative filtering techniques to recommend music additions to a user'splaylist. The impact of the deployed system has been evaluated online

    University Teachers’ Conceptions of the University and the Place of Sustainability

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    In this phenomenographic qualitative research, the aim is to learn about the conceptions of university professors about the university. The study was carried out with 20 university professors: 10 from the School of Social Sciences and 10 from the School of Science and Technology of University of Évora with an average age of 54 years and over 20 years of professional activity. The data were collected through open questionnaires and then submitted to thematic and categorical content analysis. The conceptions of the university appear, in the voice of the teachers, centered on two main aspects. The first and more mentioned concerns the conception of the university as a space of production and diffusion of scientific knowledge, which refers to quality factors of higher education. The second brings out the conception of the university as a space of relationship with society together with underlying concerns for human development, cooperation, and the design of a more sustainable world

    Antinociceptive Activity of Trichilia catigua Hydroalcoholic Extract: New Evidence on Its Dopaminergic Effects

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    Trichilia catigua is a native plant of Brazil; its barks are used by some local pharmaceutical companies to prepare tonic drinks, such as Catuama. The present study was addressed to evaluate the effects of T. catigua hydroalcoholic extract in mouse nociception behavioral models, and to evaluate the possible mechanisms involved in its actions. Male Swiss mice were submitted to hot-plate, writhing and von Frey tests, after oral treatment with T. catigua extract (200 mg kg−1, p.o.). The extract displayed antinociceptive effect in all three models. For characterization of the mechanisms involved in the antinociceptive action of the extract, the following pharmacological treatments were done: naloxone (2.5 mg kg−1, s.c.), SR141716A (10 mg kg−1, i.p.), SCH23390 (15 μg kg−1, i.p.), sulpiride (50 mg kg−1, i.p.), prazosin (1 mg kg−1, i.p.), bicuculline (1 mg kg−1, i.p.) or dl-p-chlorophenylalanine methyl ester (PCPA, 100 mg kg−1, i.p.). In these experiments, the action of T. catigua extract was evaluated in the hot-plate test. The treatment with SCH23390 completely prevented the antinociceptive effect, while naloxone partially prevented it. The possible involvement of the dopaminergic system in the actions of T. catigua extract was substantiated by data showing the potentiation of apomorphine-induced hypothermia and by the prevention of haloperidol-induced catalepsy. In conclusion, the antinociceptive effects of T. catigua extract seem to be mainly associated with the activation of dopaminergic system and, to a lesser extent, through interaction with opioid pathway

    Superpulsed low-level laser therapy protects skeletal muscle of mdx mice against damage, inflammation and morphological changes delaying dystrophy progression.

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    Aim: To evaluate the effects of preventive treatment with low-level laser therapy (LLLT) on progression of dystrophy in mdx mice. Methods: Ten animals were randomly divided into 2 experimental groups treated with superpulsed LLLT (904 nm, 15 mW, 700 Hz, 1 J) or placebo-LLLT at one point overlying the tibialis anterior muscle (bilaterally) 5 times per week for 14 weeks (from 6th to 20th week of age). Morphological changes, creatine kinase (CK) activity and mRNA gene expression were assessed in animals at 20th week of age. Results: Animals treated with LLLT showed very few morphological changes in skeletal muscle, with less atrophy and fibrosis than animals treated with placebo-LLLT. CK was significantly lower (p = 0.0203) in animals treated with LLLT (864.70 U.l−1, SEM 226.10) than placebo (1708.00 U.l−1, SEM 184.60). mRNA gene expression of inflammatory markers was significantly decreased by treatment with LLLT (p<0.05): TNF-α (placebo-control = 0.51 µg/µl [SEM 0.12], - LLLT = 0.048 µg/µl [SEM 0.01]), IL-1β (placebo-control = 2.292 µg/µl [SEM 0.74], - LLLT = 0.12 µg/µl [SEM 0.03]), IL-6 (placebo-control = 3.946 µg/µl [SEM 0.98], - LLLT = 0.854 µg/µl [SEM 0.33]), IL-10 (placebo-control = 1.116 µg/µl [SEM 0.22], - LLLT = 0.352 µg/µl [SEM 0.15]), and COX-2 (placebo-control = 4.984 µg/µl [SEM 1.18], LLLT = 1.470 µg/µl [SEM 0.73]). Conclusion: Irradiation of superpulsed LLLT on successive days five times per week for 14 weeks decreased morphological changes, skeletal muscle damage and inflammation in mdx mice. This indicates that LLLT has potential to decrease progression of Duchenne muscular dystrophy

    Substrato com Organosuper® para formação de mudas de pepineiro em ambientes protegidos e bandejas de poliestireno

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    Culture environments, trays and doses of organic compost were evaluated in the formation of cucumber seedlings (Cucumis sativus L.). Five environmental conditions were tested: (A1) a greenhouse with height of 2.5 m, covered with polyethylene film, (A2) nursery with height of 2.5 m, monofilament fabric, 50% shading, (A3) nursery with height of 2.5 m, heat-reflective screen, 50% shading, (A4) nursery with a height of 1.8 m, covered with coconut tree straw and (A5) greenhouse with height of 4.0 m, covered with polyethylene film, with zenith opening and thermo-reflective cloth under the plastic. Trays of 72 (R1) and 128 (R2) cells were filled with 93% soil and 7% organic compound (S1), 86% soil and 14% organic compound (S2) and 79% soil and 21% organic compound (S3). It was used a randomized design in split-split-plot scheme, with five replicates (environments x trays x substrates). The greenhouses provide the best environments for the formation of cucumber seedlings. A tray of 72 cells is the best container, promoting more vigorous seedlings in substrate with soil and 7 or 14% organic compound.Ambientes de cultivo, bandejas e doses de composto orgânico foram avaliados na formação de mudas de pepino (Cucumis sativus L.). Cinco ambientes de cultivo foram testados: (A1) estufa agrícola com altura de 2,5 m coberta com filme de polietileno; (A2) viveiro com altura de 2,5 m, tela de monofilamento com 50% de sombreamento; (A3) viveiro com altura de 2,5 m, tela termorrefletora, com 50% de sombreamento; (A4) viveiro com altura de 1,8 m, coberto com palha de coqueiro, e (A5) estufa agrícola com altura de 4,0 m, coberta com filme de polietileno, com abertura zenital e tela termorrefletora sob o filme. Bandejas de 72 (R1) e 128 (R2) células foram preenchidas com 93% de solo e 7% de composto orgânico (S1); 86% de solo e 14% de composto orgânico (S2), e 79% de solo e 21% de composto orgânico (S3). Utilizou-se um delineamento inteiramente casualizado, em esquema de parcelas subsubdivididas, com cinco repetições (ambientes x bandejas x substratos). As estufas agrícolas propiciam os melhores ambientes para a formação das mudas de pepino. A bandeja de 72 células é o melhor recipiente, promovendo plântulas mais vigorosas no substrato com solo e 7 ou 14 % de composto orgânico.22623

    Apreciação dos jogos por crianças e jovens em um festival de handebol

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    Nosso interesse pelo campo teórico da Praxiologia Motriz teve início no projeto de extensão universitária denominado “Ensinando e Aprendendo Handebol”, espaço no qual nos deparamos, já há quase 10 anos, com o desafio de ensinar handebol à crianças e jovens. Associados a este projeto de extensão, sentimos a necessidade de um grupo de pesquisa, no qual pudéssemos nos aprofundar nos estudos acerca da pedagogia dos esportes coletivos, surgindo, a partir do ano de 2009, o Núcleo de Estudos e Pesquisas das Abordagens Táticas dos Esportes Coletivos (NEPATEC).Departamento de Educación Físic

    Mechanical damages caused in banana Nanicão in the improvement process, packing and transport

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    This study had as objective the evaluation of mechanical damages occurred in banana Nanicão during the improvement process, packing and distribution, identifying the probable critical points. The mechanical damages caused by transport, first cleaning; cleanness and sorting; preservation in the packing, transport, and mature were evaluated. The studied packing had been: torito wooden packing (18 kg), wood type ½ box, (13 kg) and cardboard (18 kg). The stage of preservation and transport of the fruits to the distribution center duplicated the light defects and quintupled the serious defects, causing rottenness after the acclimatization. The cardboard packing did not support the piling up and presented deformations, that resulted in the kneading the fruits of the inferior packing, causing a significant increase of the serious defects. The fruits conditioned in the involved packing of plastic bubble had presented an inferior number of serious damages when compared with the others packing, without the plastic.Este estudo teve como objetivo a avaliação de danos mecânicos ocorridos na banana Nanicão durante o processo de beneficiamento, transporte, embalagem e distribuição, identificando os prováveis pontos críticos. Avaliaram-se os danos mecânicos causados após o transporte, despistilagem e primeira despenca; limpeza e classificação; acondicionamento nas embalagens e transporte, e amadurecimento. As embalagens estudadas foram: embalagem de madeira torito (18 kg), madeira tipo ½ caixa (13 kg) e papelão (18 kg). Verificou-se que, na etapa de acondicionamento e transporte das frutas até o centro de distribuição, duplicaram os defeitos leves e os defeitos graves quintuplicaram, causando podridões após a climatização. A embalagem de papelão não suportou o empilhamento e apresentou deformações, que resultaram no amassamento das frutas que estavam nas embalagens inferiores e no aumento significativo dos defeitos graves. As frutas acondicionadas nas embalagens envolvidas pelo plástico bolha apresentaram menos danos graves quando comparadas às demais embalagens, sem o plástico.195201Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES

    Heart rate variability analysis for the identification of the preictal interval in patients with drug-resistant epilepsy

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    Electrocardiogram (ECG) recordings, lasting hours before epileptic seizures, have been studied in the search for evidence of the existence of a preictal interval that follows a normal ECG trace and precedes the seizure's clinical manifestation. The preictal interval has not yet been clinically parametrized. Furthermore, the duration of this interval varies for seizures both among patients and from the same patient. In this study, we performed a heart rate variability (HRV) analysis to investigate the discriminative power of the features of HRV in the identification of the preictal interval. HRV information extracted from the linear time and frequency domains as well as from nonlinear dynamics were analysed. We inspected data from 238 temporal lobe seizures recorded from 41 patients with drug-resistant epilepsy from the EPILEPSIAE database. Unsupervised methods were applied to the HRV feature dataset, thus leading to a new perspective in preictal interval characterization. Distinguishable preictal behaviour was exhibited by 41% of the seizures and 90% of the patients. Half of the preictal intervals were identified in the 40 min before seizure onset. The results demonstrate the potential of applying clustering methods to HRV features to deepen the current understanding of the preictal state.FCT: CISUC -UID/CEC/00326/2020/ SFRH/BD/147862/2019info:eu-repo/semantics/publishedVersio

    Postharvest characterization of oranges 'Baianinha' stored under refrigeration and ambient conditions

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    The postharvest quality of fresh oranges (Citrus sinensis (L.) Osbeck, 'Baianinha') was evaluated in terms of chemical and physical properties, in May of 1998. An experiment was carried out in a completely randomized design, with two replications, submitting the fruits to two treatments: storage at ambient conditions (21 ± 0.4°C and RH = 60 ± 1.0%, and in cold room (1 ± 0,5°C and RH = 85 ± 2,5%). After 15 days of storage, a highly significant difference was observed (P=0,01) in the levels of ascorbic acid (decrease of 20% and 8%, at ambient condition and refrigerated fruits, respectively). Titratable acidity decrease approximately 14%, for fruits at ambient condition, and 8% for the refrigerated fruits. It was observed an increase of 30% (ambient condition) and 18% (refrigerated fruits), in the brix/titratable acidity ratio. The results demonstrated that there is a tendency of quality loss for fruits maintained at ambient condition. Therefore, the use of refrigeration is necessary for the maintenance of post harvest quality of fresh orange.A qualidade pós colheita de laranjas in natura (Citrus sinensis (L.) Osbeck, 'Baianinha'), foi avaliada em termos de suas propriedades químicas e físicas, em maio de 1998. Foi aplicado um delineamento inteiramente casualizado, com duas repetições, submetendo os frutos a dois tratamentos: armazenamento a temperatura ambiente (21 ± 0,4°C e UR= 60 ± 1,0%), e em uma câmara frigorífica (1 ± 0,5°C e UR = 85 ± 2,5%). Após 15 dias de armazenamento, foi observada uma diferença altamente significativa (P=0,01), nos níveis de ácido ascórbico (diminuição de 20% e 8%, nas laranjas expostas a temperatura ambiente e nos frutos refrigerados, respectivamente). A acidez titulável teve uma diminuição de aproximadamente 14%, para os frutos mantidos à temperatura ambiente, e de 8% para os frutos refrigerados. Comprovou-se um aumento de 30% (frutos em condições ambientais) e de 18% (frutos refrigerados), na relação sólidos solúveis e acidez titulável. Os resultados apontam uma tendência à perda da qualidade nos frutos mantidos em condições ambientais, o que reafirma a necessidade do uso de refrigeração para a conservação pós-colheita de laranja in natura.464
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