Global Competitiveness and Canadian Sectoral/Regional Labour Productivity Differences

This paper evaluates the extent to which the decrease in total factor productivity growth that is alleged to have occurred in the last few years is also reflected in corresponding decreases in labour productivity growth, among key provinces and sectors of the Canadian economy. The analysis is based upon non-parametric productivity comparisons, for the 1984-1998 period. Data envelopment analysis is the methodological tool selected for the measurement of total factor productivity and hence of operational effectiveness to assess the extent to which sectoral productivity differences across Canadian regions represents a barometer of global competitiveness. The evidence indicates that labour productivity is growing. Factors associated with economies of scale appear to be the main source of inefficiency, as expected in a spatial setting. These inefficiencies are reflected mostly in increasing returns to scale, which enhances the competitiveness potential of the regions' economic base and of the industries in their midst

Non-Traditional Music Classes in Secondary Public School Music Programs

Abstract As U.S. demographics continue to change and schools become more diverse, music classes have evolved to better reflect their student populations. Music classes operate differently than they have in the past and offer new ways for students to receive a musical education. This thesis advocates for Non-Traditional music classes as accessible options in secondary public school music programs for students who have not opted to be involved past elementary school. Included is a discussion of the benefits of Non-Traditional music education as well as an analysis of possible barricades that may have discouraged students from participation in traditional ensemble based programs. To support this position, Washington State teachers were interviewed to profile how their inclusion of Non-Traditional music classes reflect student cultures, interests and needs. An example curriculum proposal is provided to show how a Non-Traditional music class may be developed

Spatial Scaling of Avian Population Dynamics: Population Abundance, Growth Rate, and Variability

Synchrony in population fluctuations has been identified as an important component of population dynamics. In a previous study, we determined that local‐scale (\u3c15‐km) spatial synchrony of bird populations in New England was correlated with synchronous fluctuations in lepidopteran larvae abundance and with the North Atlantic Oscillation. Here we address five questions that extend the scope of our earlier study using North American Breeding Bird Survey data. First, do bird populations in eastern North America exhibit spatial synchrony in abundances at scales beyond those we have documented previously? Second, does spatial synchrony depend on what population metric is analyzed (e.g., abundance, growth rate, or variability)? Third, is there geographic concordance in where species exhibit synchrony? Fourth, for those species that exhibit significant geographic concordance, are there landscape and habitat variables that contribute to the observed patterns? Fifth, is spatial synchrony affected by a species\u27 life history traits? Significant spatial synchrony was common and its magnitude was dependent on the population metric analyzed. Twenty‐four of 29 species examined exhibited significant synchrony in population abundance: mean local autocorrelation (ρ) = 0.15; mean spatial extent (mean distance where ρ = 0) = 420.7 km. Five of the 29 species exhibited significant synchrony in annual population growth rate (mean local autocorrelation = 0.06, mean distance = 457.8 km). Ten of the 29 species exhibited significant synchrony in population abundance variability (mean local autocorrelation = 0.49, mean distance = 413.8 km). Analyses of landscape structure indicated that habitat variables were infrequent contributors to spatial synchrony. Likewise, we detected no effects of life history traits on synchrony in population abundance or growth rate. However, short‐distance migrants exhibited more spatially extensive synchrony in population variability than either year‐round residents or long‐distance migrants. The dissimilarity of the spatial extent of synchrony across species suggests that most populations are not regulated at similar spatial scales. The spatial scale of the population synchrony patterns we describe is likely larger than the actual scale of population regulation, and in turn, the scale of population regulation is undoubtedly larger than the scale of individual ecological requirements

Is PPARγ a Prospective Player in HIV-1-Associated Bone Disease?

Currently infection with the human immunodeficiency virus-1 (HIV-1) is in most instances a chronic disease that can be controlled by effective antiretroviral therapy (ART). However, chronic use of ART has been associated with a number of toxicities; including significant reductions in bone mineral density (BMD) and disorders of the fat metabolism. The peroxisome proliferator-activated receptor gamma (PPARγ) transcription factor is vital for the development and maintenance of mature and developing adipocytes. Alterations in PPARγ expression have been implicated as a factor in the mechanism of HIV-1-associated lipodystrophy. Both reduced BMD and lipodystrophy have been well described as complications of HIV-1 infection and treatment, and a question remains as to their interdependence. Interestingly, both adipocytes and osteoblasts are derived from a common precursor cell type; the mesenchymal stem cell. The possibility that dysregulation of PPARγ (and the subsequent effect on both osteoblastogenesis and adipogenesis) is a contributory factor in the lipid- and bone-abnormalities observed in HIV-1 infection and treatment has also been investigated. This review deals with the hypothesis that dysregulation of PPARγ may underpin the bone abnormalities associated with HIV-1 infection, and treats the current knowledge and prospective developments, in our understanding of PPARγ involvement in HIV-1-associated bone disease

Soliton switching using cascaded nonlinear-optical loop mirrors

We demonstrate multiple-peaked switching in a nonlinear-optical loop mirror and present an experimental investigation of device cascading in the soliton regime based on a sequence of two independent nonlinear-optical loop mirrors. Cascading leads to an enhanced switching response with sharper switching edges, flattened peaks, and increased interpeak extinction ratios. We observe that pulses emerging from the cascade retain the sech2 temporal profile of a soliton with minimal degradation in the spectral characteristics

Joint analysis of stressors and ecosystem services to enhance restoration effectiveness

With increasing pressure placed on natural systems by growing human populations, both scientists and resource managers need a better understanding of the relationships between cumulative stress from human activities and valued ecosystem services. Societies often seek to mitigate threats to these services through large-scale, costly restoration projects, such as the over one billion dollar Great Lakes Restoration Initiative currently underway. To help inform these efforts, we merged high-resolution spatial analyses of environmental stressors with mapping of ecosystem services for all five Great Lakes. Cumulative ecosystem stress is highest in near-shore habitats, but also extends offshore in Lakes Erie, Ontario, and Michigan. Variation in cumulative stress is driven largely by spatial concordance among multiple stressors, indicating the importance of considering all stressors when planning restoration activities. In addition, highly stressed areas reflect numerous different combinations of stressors rather than a single suite of problems, suggesting that a detailed understanding of the stressors needing alleviation could improve restoration planning. We also find that many important areas for fisheries and recreation are subject to high stress, indicating that ecosystem degradation could be threatening key services. Current restoration efforts have targeted high-stress sites almost exclusively, but generally without knowledge of the full range of stressors affecting these locations or differences among sites in service provisioning. Our results demonstrate that joint spatial analysis of stressors and ecosystem services can provide a critical foundation for maximizing social and ecological benefits from restoration investments. www.pnas.org/lookup/suppl/doi:10.1073/pnas.1213841110/-/DCSupplementa

Lidar remote sensing variables predict breeding habitat of a Neotropical migrant bird

A topic of recurring interest in ecological research is the degree to which vegetation structure influences the distribution and abundance of species. Here we test the applicability of remote sensing, particularly novel use of waveform lidar measurements, for quantifying the habitat heterogeneity of a contiguous northern hardwoods forest in the northeastern United States. We apply these results to predict the breeding habitat quality, an indicator of reproductive output of a well-studied Neotropical migrant songbird, the Blackthroated Blue Warbler (Dendroica caerulescens). We found that using canopy vertical structure metrics provided unique information for models of habitat quality and spatial patterns of prevalence. An ensemble decision tree modeling approach (random forests) consistently identified lidar metrics describing the vertical distribution and complexity of canopy elements as important predictors of habitat use over multiple years. Although other aspects of habitat were important, including the seasonality of vegetation cover, the canopy structure variables provided unique and complementary information that systematically improved model predictions. We conclude that canopy structure metrics derived from waveform lidar, which will be available on future satellite missions, can advance multiple aspects of biodiversity research, and additional studies should be extended to other organisms and regions.Key words: bird diversity; Black-throated Blue Warbler; canopy structure; Dendroica caerulescens; habitat quality; Hubbard Brook Experimental Forest, New Hampshire, USA; Neotropical migratory birds; northern hardwoods forests; remote sensing; waveform lidar data

FIRE (facilitating implementation of research evidence) : a study protocol

Research evidence underpins best practice, but is not always used in healthcare. The Promoting Action on Research Implementation in Health Services (PARIHS) framework suggests that the nature of evidence, the context in which it is used, and whether those trying to use evidence are helped (or facilitated) affect the use of evidence. Urinary incontinence has a major effect on quality of life of older people, has a high prevalence, and is a key priority within European health and social care policy. Improving continence care has the potential to improve the quality of life for older people and reduce the costs associated with providing incontinence aids

Rating impacts in a multi‐stressor world: a quantitative assessment of 50 stressors affecting the Great Lakes

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/116318/1/eap2015253717.pd

High Throughput Genome-Wide Survey of Small RNAs from the Parasitic Protists Giardia intestinalis and Trichomonas vaginalis

RNA interference (RNAi) is a set of mechanisms which regulate gene expression in eukaryotes. Key elements of RNAi are small sense and antisense RNAs from 19 to 26 nt generated from double-stranded RNAs. MicroRNAs (miRNAs) are a major type of RNAi-associated small RNAs and are found in most eukaryotes studied to date. To investigate whether small RNAs associated with RNAi appear to be present in all eukaryotic lineages, and therefore present in the ancestral eukaryote, we studied two deep-branching protozoan parasites, Giardia intestinalis and Trichomonas vaginalis. Little is known about endogenous small RNAs involved in RNAi of these organisms. Using Illumina Solexa sequencing and genome-wide analysis of small RNAs from these distantly related deep-branching eukaryotes, we identified 10 strong miRNA candidates from Giardia and 11 from Trichomonas. We also found evidence of Giardia short-interfering RNAs potentially involved in the expression of variant-specific surface proteins. In addition, eight new small nucleolar RNAs from Trichomonas are identified. Our results indicate that miRNAs are likely to be general in ancestral eukaryotes and therefore are likely to be a universal feature of eukaryotes