Women and Public Life in Early Meiji Japan

Women and Public Life in Early Meiji Japan focuses on women’s activities in the new public spaces of Meiji Japan. With chapters on public, private, and missionary schools for girls, their students, and teachers, on social and political groups women created, on female employment, and on women’s participation in print media, this book offers a new perspective on nineteenth- and early twentieth-century Japanese history. Women’s founding of and participation in conflicting discourses over the value of women in Meiji public life demonstrate that during this period active and vocal women were everywhere, that they did not meekly submit to the dictates of the government and intellectuals over what women could or should do, and that they were fully integrated in the production of Meiji culture. Mara Patessio shows that the study of women is fundamental not only in order to understand fully the transformations of the Meiji period, but also to understand how later generations of women could successfully move the battle forward. Women and Public Life in Early Meiji Japan is essential reading for all students and teachers of 19th- and early 20th-century Japanese history and is of interest to scholars of women’s history more generally

Women and Public Life in Early Meiji Japan

Women and Public Life in Early Meiji Japan focuses on women’s activities in the new public spaces of Meiji Japan. With chapters on public, private, and missionary schools for girls, their students, and teachers, on social and political groups women created, on female employment, and on women’s participation in print media, this book offers a new perspective on nineteenth- and early twentieth-century Japanese history. Women’s founding of and participation in conflicting discourses over the value of women in Meiji public life demonstrate that during this period active and vocal women were everywhere, that they did not meekly submit to the dictates of the government and intellectuals over what women could or should do, and that they were fully integrated in the production of Meiji culture. Mara Patessio shows that the study of women is fundamental not only in order to understand fully the transformations of the Meiji period, but also to understand how later generations of women could successfully move the battle forward. Women and Public Life in Early Meiji Japan is essential reading for all students and teachers of 19th- and early 20th-century Japanese history and is of interest to scholars of women’s history more generally

Efficacy of pulmonary rehabilitation in chronic respiratory failure (CRF) due to chronic obstructive pulmonary disease (COPD): The Maugeri Study.

14noWhile the effectiveness of pulmonary rehabilitation (PR) in chronic obstructive pulmonary disease (COPD) is well established, its effectiveness in the most severe category of COPD, i.e. patients with chronic respiratory failure (CRF), is less well known. OBJECTIVE: To verify the effects of PR in patients with CRF, and compare the level of improvement with PR in these patients to that of COPDs not affected by CRF. METHODS: A multi-centre study was carried out on COPD patients with versus without CRF. The PR program included educational support, exercise training, and nutritional and psychological counselling. Lung function, arterial gases, walk test (6MWT), dyspnoea (MRC; BDI/TDI), and quality of life (MRF(28); SGRQ) were evaluated. RESULTS: Thousand forty seven consecutive COPD inpatients (327 with CRF) were evaluated. In patients with CRF all parameters improved after PR (0.001). Mean changes: FEV(1), 112 ml; PaO(2), 3.0 mmHg; PaCO(2), 3.3 mmHg; 6MWT, 48 m; MRC, 0.85 units; MRF(28) total score, 11.5 units. These changes were similar to those observed in patients without CRF. CONCLUSIONS: This study, featuring the largest cohort so far reported in the literature, shows that PR is equally effective in the more severe COPD patients, i.e. those with CRF, and supports the prescription of PR also in these patients.nonemixedCARONE M; PATESSIO A; AMBROSINO N; BAIARDI P; BALBI B; BALZANO G; CUOMO V; DONNER CF; FRACCHIA C; NAVA S; NERI M; POZZI E; VITACCA M; SPANEVELLO A.Carone, M; Patessio, A; Ambrosino, N; Baiardi, P; Balbi, B; Balzano, G; Cuomo, V; Donner, Cf; Fracchia, C; Nava, S; Neri, M; Pozzi, E; Vitacca, M; Spanevello, Antoni

Value of supplemental interventions to enhance the effectiveness of physical exercise during respiratory rehabilitation in COPD patients. A Systematic Review

BACKGROUND: There is a controversy about the additional benefit of various supplemental interventions used in clinical practice to further enhance the effectiveness of respiratory rehabilitation in patients with Chronic obstructive pulmonary disease (COPD). The aim of this research was to assess randomised controlled trials (RCTs) testing the additional benefit of supplemental interventions during respiratory rehabilitation in COPD patients. METHODS: Systematic review with literature searches in six electronic databases, extensive hand-searching and contacting of authors. Two reviewers selected independently eligible RCTs, rated the methodological quality and extracted the data, which were analyzed considering the minimal important difference of patient-important outcomes where possible. FINDINGS: We identified 20 RCTs whereof 18 provided sufficient data for analysis. The methodological quality was low and sample sizes were too small for most trials to produce meaningful results (median total sample size = 28). Data from five trials showed that supplemental oxygen during exercise did not have clinically meaningful effects on health-related quality of life while improvements of exercise capacity may be even larger for patients exercising on room air. RCTs of adding assisted ventilation, nutritional supplements or a number of anabolically acting drugs do not provide sufficient evidence for or against the use any of these supplemental interventions. INTERPRETATION: There is insufficient evidence for most supplemental interventions during respiratory rehabilitation to estimate their additional value, partly due to methodological shortcomings of included RCTs. Current data do not suggest benefit from supplemental oxygen during exercise, although the methodological quality of included trials limits conclusions. To appropriately assess any of the various supplemental interventions used in clinical practice, pragmatic trials on respiratory rehabilitation of COPD patients need to consider methodological aspects as well as appropriate sample sizes

Structural and functional changes of peripheral muscles in chronic obstructive pulmonary disease patients

PURPOSE OF REVIEW: The purpose of this review is to identify new advances in our understanding of skeletal muscle dysfunction in patients with COPD. RECENT FINDINGS: Recent studies have confirmed the relevance of muscle dysfunction as an independent prognosis factor in COPD. Animal studies have shed light on the molecular mechanisms governing skeletal muscle hypertrophy/atrophy. Recent evidence in patients with COPD highlighted the contribution of protein breakdown and mitochondrial dysfunction as pathogenic mechanisms leading to muscle dysfunction in these patients. SUMMARY: Chronic Obstructive Pulmonary Disease (COPD) is a debilitating disease impacting negatively on health status and the functional capacity of patients. COPD goes beyond the lungs and incurs significant systemic effects among which muscle dysfunction/wasting in one of the most important. Muscle dysfunction is a prominent contributor to exercise limitation, healthcare utilization and an independent predictor of morbidity and mortality. Gaining more insight into the molecular mechanisms leading to muscle dysfunction/wasting is key for the development of new and tailored therapeutic strategies to tackle skeletal muscle dysfunction/wasting in COPD patients