The role of antibiotics in the treatment of chronic prostatitis: A consensus statement

Practical guidelines for the diagnosis and treatment of chronic prostatitis are presented. Chronic prostatitis is classified as chronic bacterial prostatitis (culture-positive) and chronic inflammatory prostatitis (culture-negative). If chronic bacterial prostatitis is suspected, based on relevant symptoms or recurrent UTIs, underlying urological conditions should be excluded by the following tests: rectal examination, midstream urine culture and residual urine. The diagnosis should be confirmed by the Meares and Stamey technique. Antibiotic therapy is recommended for acute exacerbations of chronic prostatitis, chronic bacterial prostatitis and chronic inflammatory prostatitis, if there is clinical, bacteriological or supporting immunological evidence of prostate infection. Unless a patient presents with fever, antibiotic treatment should not be initiated immediately except in cases of acute prostatitis or acute episodes in a patient with chronic bacterial prostatitis. The work-up, with the appropriate investigations should be done first, within a reasonable time period which, preferably, should not be longer than 1 week. During this period, nonspecific treatment, such as appropriate analgesia to relieve symptoms, should be given. The minimum duration of antibiotic treatment should be 2-4 weeks. If there is no improvement in symptoms, treatment should be stopped and reconsidered. However, if there is improvement, it should be continued for at least a further 2-4 weeks to achieve clinical cure and, hopefully, eradication of the causative pathogen. Antibiotic treatment should not be given for 6-8 weeks without an appraisal of its effectiveness. Currently used antibiotics are reviewed. Of these, the fluoroquinolones ofloxacin and ciprofloxacin are recommended because of their favourable antibacterial spectrum and pharmacokinetic profile. A number of clinical trials are recommended and a standard study design is proposed to help resolve some outstanding issues

Pulsational instability of yellow hypergiants

Instability of population I (X=0.7, Y=0.02) massive stars against radial oscillations during the post-main sequence gravitational contraction of the helium core is investigated. Initial stellar masses are in the range from 65M_\odot to 90M_\odot. In hydrodynamic computations of self-exciting stellar oscillations we assumed that energy transfer in the envelope of the pulsating star is due to radiative heat conduction and convection. The convective heat transfer was treated in the framework of the theory of time-dependent turbulent convection. During evolutionary expansion of outer layers after hydrogen exhaustion in the stellar core the star is shown to be unstable against radial oscillations while its effective temperature is Teff > 6700K for Mzams=65M_\odot and Teff > 7200K for mzams=90M_\odot. Pulsational instability is due to the \kappa-mechanism in helium ionization zones and at lower effective temperature oscillations decay because of significantly increasing convection. The upper limit of the period of radial pulsations on this stage of evolution does not exceed 200 day. Radial oscillations of the hypergiant resume during evolutionary contraction of outer layers when the effective temperature is Teff > 7300K for Mzams=65M_\odot and Teff > 7600K for Mzams=90M_\odot. Initially radial oscillations are due to instability of the first overtone and transition to fundamental mode pulsations takes place at higher effective temperatures (Teff > 7700K for Mzams=65M_\odot and Teff > 8200K for Mzams=90M_\odot). The upper limit of the period of radial oscillations of evolving blueward yellow hypergiants does not exceed 130 day. Thus, yellow hypergiants are stable against radial stellar pulsations during the major part of their evolutionary stage.Comment: 20 pages, 7 gigures. Accepted for publication in Astronomy Letter

Near and mid-IR sub-arcsecond structure of the dusty symbiotic star R Aqr

The results of a high-resolution interferometric campaign targeting the symbiotic long-period variable (LPV) R~Aqr are reported. With both near-infrared measurements on baselines out to 10m and mid-infrared data extending to 32m, we have been able to measure the characteristic sizes of regions from the photosphere of the LPV and its extended molecular atmosphere, out to the cooler circumstellar dust shell. The near-infrared data were taken using aperture masking interferometry on the Keck-I telescope and show R~Aqr to be partially resolved for wavelengths out to 2.2 microns but with a marked enlargement, possibly due to molecular opacity, at 3.1 microns. Mid-infrared interferometric measurements were obtained with the U.C. Berkeley Infrared Spatial Interferometer (ISI) operating at 11.15 microns from 1992 to 1999. Although this dataset is somewhat heterogeneous with incomplete coverage of the Fourier plane and sampling of the pulsation cycle, clear changes in the mid-infrared brightness distribution were observed, both as a function of position angle on the sky and as a function of pulsation phase. Spherically symmetric radiative transfer calculations of uniform-outflow dust shell models produce brightness distributions and spectra which partially explain the data, however limitations to this approximation are noted. Evidence for significant deviation from circular symmetry was found in the mid-infrared and more tentatively at 3.08 microns in the near-infrared, however no clear detection of binarity or of non-LPV elements in the symbiotic system is reported.Comment: Accepted to Astrophysical Journal. To appear in volume 534. 14 pages; 3 postscript figure

A VLT/FLAMES survey for massive binaries in Westerlund 1: I. First observations of luminous evolved stars

Aims. Multiwavelength observations of the young massive cluster Westerlund 1 have revealed evidence for a large number of OB supergiant and Wolf-Rayet binaries. However, in most cases these findings are based on the detection of secondary binary characteristics, such as hard X-ray emission and/or non-thermal radio spectra and hence provide little information on binary properties such as mass ratio and orbital period. To overcome this shortcoming we have initiated a long temporal baseline, multi-epoch radial velocity survey that will provide the first direct constraints on these parameters.Methods. VLT/FLAMES+GIRAFFE observations of Wd1 were made on seven epochs from late-June to early-September 2008, covering ~35 confirmed members of Wd1 and ~70 photometrically-selected candidate members. Each target was observed on a minimum of three epochs, with brighter cluster members observed on five (or, in a few cases, seven) occasions. Individual spectra cover the 8484–9001 Å range, and strong Paschen-series absorption lines are used to measure radial velocity changes in order to identify candidate binary systems for follow-up study.Results. This study presents first-epoch results from twenty of the most luminous supergiant stars in Wd1. Four new OB supergiant members of Wd1 are identified, while statistically significant radial velocity changes are detected in ~60% of the targets. W43a is identified as a short-period binary, while W234 and the newly-identified cluster member W3003 are probable binaries and W2a is a strong binary candidate. The cool hypergiants W243 and W265 display photospheric pulsations, while a number of early-mid B supergiants display significant radial velocity changes of ~15–25 km s-1 that we cannot distinguish between orbital or photospheric motion in our initial short-baseline survey. When combined with existing observations, we find 30% of our sample to be binary (6/20) while additional candidate binaries support a binary fraction amongst Wd1 supergiants in excess of ~40%, a figure that is likely to increase as further data become available

A Far-Ultraviolet Spectroscopic Survey of Luminous Cool Stars

FUSE ultraviolet spectra of 8 giant and supergiant stars reveal that high temperature (3 X 10^5 K) atmospheres are common in luminous cool stars and extend across the color-magnitude diagram from Alpha Car (F0 II) to the cool giant Alpha Tau (K5 III). Emission present in these spectra includes chromospheric H-Lyman Beta, Fe II, C I, and transition region lines of C III, O VI, Si III, Si IV. Emission lines of Fe XVIII and Fe XIX signaling temperatures of ~10^7 K and coronal material are found in the most active stars, Beta Cet and 31 Com. A short-term flux variation, perhaps a flare, was detected in Beta Cet during our observation. Stellar surface fluxes of the emission of C III and O VI are correlated and decrease rapidly towards the cooler stars, reminiscent of the decay of magnetically-heated atmospheres. Profiles of the C III (977A) lines suggest that mass outflow is underway at T~80,000 K, and the winds are warm. Indications of outflow at higher temperatures (3 X 10^5K) are revealed by O VI asymmetries and the line widths themselves. High temperature species are absent in the M-supergiant Alpha Ori. Narrow fluorescent lines of Fe II appear in the spectra of many giants and supergiants, apparently pumped by H Lyman Alpha, and formed in extended atmospheres. Instrumental characteristics that affect cool star spectra are discussed.Comment: Accept for publication in The Astrophysical Journal; 22 pages of text, 23 figures and 8 table

Seismic constraints on the radial dependence of the internal rotation profiles of six Kepler subgiants and young red giants

Context : We still do not know which mechanisms are responsible for the transport of angular momentum inside stars. The recent detection of mixed modes that contain the signature of rotation in the spectra of Kepler subgiants and red giants gives us the opportunity to make progress on this issue. Aims: Our aim is to probe the radial dependance of the rotation profiles for a sample of Kepler targets. For this purpose, subgiants and early red giants are particularly interesting targets because their rotational splittings are more sensitive to the rotation outside the deeper core than is the case for their more evolved counterparts. Methods: We first extract the rotational splittings and frequencies of the modes for six young Kepler red giants. We then perform a seismic modeling of these stars using the evolutionary codes CESAM2k and ASTEC. By using the observed splittings and the rotational kernels of the optimal models, we perform inversions of the internal rotation profiles of the six stars. Results: We obtain estimates of the mean rotation rate in the core and in the convective envelope of these stars. We show that the rotation contrast between the core and the envelope increases during the subgiant branch. Our results also suggest that the core of subgiants spins up with time, contrary to the RGB stars whose core has been shown to spin down. For two of the stars, we show that a discontinuous rotation profile with a deep discontinuity reproduces the observed splittings significantly better than a smooth rotation profile. Interestingly, the depths that are found most probable for the discontinuities roughly coincide with the location of the H-burning shell, which separates the layers that contract from those that expand. These results will bring observational constraints to the scenarios of angular momentum transport in stars.Comment: Accepted in A&A, 27 pages, 18 figure

Developing reading-writing connections; the impact of explicit instruction of literary devices on the quality of children's narrative writing

The purpose of this collaborative schools-university study was to investigate how the explicit instruction of literary devices during designated literacy sessions could improve the quality of children's narrative writing. A guiding question for the study was: Can children's writing can be enhanced by teachers drawing attention to the literary devices used by professional writers or “mentor authors”? The study was conducted with 18 teachers, working as research partners in nine elementary schools over one school year. The research group explored ways of developing children as reflective authors, able to draft and redraft writing in response to peer and teacher feedback. Daily literacy sessions were complemented by weekly writing workshops where students engaged in authorial activity and experienced writers' perspectives and readers' demands (Harwayne, 1992; May, 2004). Methods for data collection included video recording of peer-peer and teacher-led group discussions and audio recording of teacher-child conferences. Samples of children's narrative writing were collected and a comparison was made between the quality of their independent writing at the beginning and end of the research period. The research group documented the importance of peer-peer and teacher-student discourse in the development of children's metalanguage and awareness of audience. The study suggests that reading, discussing, and evaluating mentor texts can have a positive impact on the quality of children's independent writing

Bolometric luminosity variations in the Luminous Blue Variable AFGL2298

We characterise the variability in the physical properties of the luminous blue variable AFGL2298 between 1989-2008. In conjunction with published data from 1989-2001, we have undertaken a long term (2001-2008) near-IR spectroscopic and photometric observational campaign for this star and utilise a non-LTE model atmosphere code to interpret these data. We find AFGL2298 to have been highly variable during the two decades covered by the observational datasets. Photometric variations of >1.6 mag have been observed in the JHK wavebands; however, these are not accompanied by correlated changes in near-IR colour. Non-LTE model atmosphere analysis of 4 epochs of K band spectroscopy obtained between 2001-7 suggests that the photometric changes were driven by expansion and contraction of the stellar photosphere accompanied by comparatively small changes in the stellar temperature. Unclumped mass loss rates throughout this period were modest and directly comparable to those of other highly luminous LBVs. However, the bolometric luminosity of AFGL2298 appears to have varied by at least a factor of ~2 between 1989-2008, with it being one of the most luminous stars in the Galaxy during maximum. Comparison to other LBVs that have undergone non bolometric luminosity conserving `eruptions' shows such events to be heterogeneous, with AFGL2298 the least extreme example. These results - and the diverse nature of both the quiescent LBVs and associated ejecta - may offer support to the suggestion that more than one physical mechanism is responsible for such behaviour. [ABRIDGED]Comment: 12 pages, 6 figures, accepted for publication in Astronomy and Astrophysic

On the Binarity of LBV Stars

We report on the binarity of luminous blue variable stars observed with a set of techniques and instruments. Among them, observations at high angular resolution with the VLT-NACO, the VLTI-AMBER and with spectrographs such as the VLT-XSHOOTER allowed us to find several LBV stars as binaries or having a potential companion. In particular the LBV Pistol Star clearly presents radial velocity variations and line profiles modifications (double peak appearance). In addition, the absorption component of the P Cygni lines varies as well with the time indicating a potential wind structure variability. Our observations also show directly for the first time a companion to at least one of the observed LBVs (HD 168625). This one seems to affect the environment of the system. This system is known to be surrounded by several rings similar to those of SN1987A, possibly indicating a future supernova occurrence for this Galactic object. These results show that Eta Car is no longer unique

Atmospheric Heating and Wind Acceleration: Results for Cool Evolved Stars based on Proposed Processes

A chromosphere is a universal attribute of stars of spectral type later than ~F5. Evolved (K and M) giants and supergiants (including the zeta Aurigae binaries) show extended and highly turbulent chromospheres, which develop into slow massive winds. The associated continuous mass loss has a significant impact on stellar evolution, and thence on the chemical evolution of galaxies. Yet despite the fundamental importance of those winds in astrophysics, the question of their origin(s) remains unsolved. What sources heat a chromosphere? What is the role of the chromosphere in the formation of stellar winds? This chapter provides a review of the observational requirements and theoretical approaches for modeling chromospheric heating and the acceleration of winds in single cool, evolved stars and in eclipsing binary stars, including physical models that have recently been proposed. It describes the successes that have been achieved so far by invoking acoustic and MHD waves to provide a physical description of plasma heating and wind acceleration, and discusses the challenges that still remain.Comment: 46 pages, 9 figures, 1 table; modified and unedited manuscript; accepted version to appear in: Giants of Eclipse, eds. E. Griffin and T. Ake (Berlin: Springer