Design and Implementation of a Voltage Tracking with Artificial Neural Network Controller for a Double-input Buck-Boost Converter

This paper proposes an Artificial Neural Network (ANN) control voltage tracking scheme of a double-input buckboost DC-DC converter. In this topology, a back-propagation algorithm topology is implemented. The controller is developed to improve the performance of the double-input converter during transient and steady-state operations. The neural network controller design, which is developed against output voltage command tracking is proposed. The proposed concept has been investigated and validated experimentally on a laboratory prototype using DSP TMS320F28335real time digital controller to verify the dynamic response of the proposed controller. The experimental results confirm the validity of the proposed neural network control technique, which is a promising an efficient control topology that ensures doubleinput converter suitable for electric vehicle and renewable energy applications

A battery integrated multiple input DC-DC boost converter

In this paper, the proposed single boost converter aims to harness more than one renewable energy (RE) input source and achieve a high voltage gain. The interleaved technique combined with voltage multiplier (VM) cells, reduced inductor current and attained high voltage transfer ratio. The boost converter possesses two unidirectional input ports and a bidirectional input port that is connected to a battery storage. The duty ratios of the power and interleaving switches are used to regulate the output voltage of the proposed converter. Three operation modes are identified, and steady state analyses of the converter are presented and discussed. The converter can store excess energy in the battery during periods of abundance and deliver power to the loads when the RE sources are low or unavailable. In addition, the output voltage is higher than that of the conventional boost converter. The converter delivered 278 V from 12 V and 24 V dual input sources. The converter operation is simulated and verified using MATLAB/Simulink

A Review of Sarawak Off-Grid Renewable Energy Potential and Challenges

Sarawak is the largest state in Malaysia, in spite of this, the population of Sarawak is relatively small and 42 percent of that population residing in the rural areas. Consequently, the Sarawak government is facing immense challenges in providing basic need such as electricity to the entire state due to the remoteness and small sizes of these settlements. Although the state produces sufficient amount of power, the cost of connecting these rural and non-rural small settlements to the grid is just impractical. The current energy scenario in Sarawak will be reviewed with a focus on the two reliable renewable energy resources currently being pursued by the Local Electrical Authority (LEA) for rural electrification projects which are the Hydro Power and Solar Energy. The paper will address the technical and localized challenges facing the micro-hydro and solar electric energy generation in Sarawak. The micro hydropower potential in Sarawak is estimated at 10.2MW but is not being fully developed due to difficulty in distinctive design and implementation which requires full participation and support from the local community to make it more economically viable and functionality in long run. In addition, Sarawak also receives a daily solar irradiation of more than 5 KWh/m2 throughout the year and that means huge potential for it to thrive. But design and implementation must be done carefully due to the tropical climate and operating temperature of the components. Ultimately, both renewable energy systems require trained personnel to attend to and involvement of LEA or any appointed agency to provide assistance and coordination are necessary to ensure greater success in rural electrification projects

Adenosine A2A receptors: localization and function

Adenosine is an endogenous purine nucleoside present in all mammalian tissues, that originates from the breakdown of ATP. By binding to its four receptor subtypes (A1, A2A, A2B, and A3), adenosine regulates several important physiological functions at both the central and peripheral levels. Therefore, ligands for the different adenosine receptors are attracting increasing attention as new potential drugs to be used in the treatment of several diseases. This chapter is aimed at providing an overview of adenosine metabolism, adenosine receptors localization and their signal transduction pathways. Particular attention will be paid to the biochemistry and pharmacology of A2A receptors, since antagonists of these receptors have emerged as promising new drugs for the treatment of Parkinson's disease. The interactions of A2A receptors with other nonadenosinergic receptors, and the effects of the pharmacological manipulation of A2A receptors on different body organs will be discussed, together with the usefulness of A2A receptor antagonists for the treatment of Parkinson's disease and the potential adverse effects of these drugs

De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures.

Next-generation sequencing has been invaluable in the elucidation of the genetic etiology of many subtypes of intellectual disability in recent years. Here, using exome sequencing and whole-genome sequencing, we identified three de novo truncating mutations in WAS protein family member 1 (WASF1) in five unrelated individuals with moderate to profound intellectual disability with autistic features and seizures. WASF1, also known as WAVE1, is part of the WAVE complex and acts as a mediator between Rac-GTPase and actin to induce actin polymerization. The three mutations connected by Matchmaker Exchange were c.1516C>T (p.Arg506Ter), which occurs in three unrelated individuals, c.1558C>T (p.Gln520Ter), and c.1482delinsGCCAGG (p.Ile494MetfsTer23). All three variants are predicted to partially or fully disrupt the C-terminal actin-binding WCA domain. Functional studies using fibroblast cells from two affected individuals with the c.1516C>T mutation showed a truncated WASF1 and a defect in actin remodeling. This study provides evidence that de novo heterozygous mutations in WASF1 cause a rare form of intellectual disability

Bacteria-inducing legume nodules involved in the improvement of plant growth, health and nutrition

Bacteria-inducing legume nodules are known as rhizobia and belong to the class Alphaproteobacteria and Betaproteobacteria. They promote the growth and nutrition of their respective legume hosts through atmospheric nitrogen fixation which takes place in the nodules induced in their roots or stems. In addition, rhizobia have other plant growth-promoting mechanisms, mainly solubilization of phosphate and production of indoleacetic acid, ACC deaminase and siderophores. Some of these mechanisms have been reported for strains of rhizobia which are also able to promote the growth of several nonlegumes, such as cereals, oilseeds and vegetables. Less studied are the mechanisms that have the rhizobia to promote the plant health; however, these bacteria are able to exert biocontrol of some phytopathogens and to induce the plant resistance. In this chapter, we revised the available data about the ability of the legume nodule-inducing bacteria for improving the plant growth, health and nutrition of both legumes and nonlegumes. These data showed that rhizobia meet all the requirements of sustainable agriculture to be used as bio-inoculants allowing the total or partial replacement of chemicals used for fertilization or protection of crops

The behaviour of giant clams (Bivalvia: Cardiidae: Tridacninae)

Giant clams, the largest living bivalves, live in close association with coral reefs throughout the Indo-Pacific. These iconic invertebrates perform numerous important ecological roles as well as serve as flagship species—drawing attention to the ongoing destruction of coral reefs and their associated biodiversity. To date, no review of giant clams has focussed on their behaviour, yet this component of their autecology is critical to their life history and hence conservation. Almost 100 articles published between 1865 and 2014 include behavioural observations, and these have been collated and synthesised into five sections: spawning, locomotion, feeding, anti-predation, and stress responses. Even though the exact cues for spawning in the wild have yet to be elucidated, giant clams appear to display diel and lunar periodicities in reproduction, and for some species, peak breeding seasons have been established. Perhaps surprisingly, giant clams have considerable mobility, ranging from swimming and gliding as larvae to crawling in juveniles and adults. Chemotaxis and geotaxis have been established, but giant clams are not phototactic. At least one species exhibits clumping behaviour, which may enhance physical stabilisation, facilitate reproduction, or provide protection from predators. Giant clams undergo several shifts in their mode of acquiring nutrition; starting with a lecithotrophic and planktotrophic diet as larvae, switching to pedal feeding after metamorphosis followed by the transition to a dual mode of filter feeding and phototrophy once symbiosis with zooxanthellae (Symbiodinium spp.) is established. Because of their shell weight and/or byssal attachment, adult giant clams are unable to escape rapidly from threats using locomotion. Instead, they exhibit a suite of visually mediated anti-predation behaviours that include sudden contraction of the mantle, valve adduction, and squirting of water. Knowledge on the behaviour of giant clams will benefit conservation and restocking efforts and help fine-tune mariculture techniques. Understanding the repertoire of giant clam behaviours will also facilitate the prediction of threshold levels for sustainable exploitation as well as recovery rates of depleted clam populations