Degradabilitas Bahan Kering, Bahan Organik dan Serat Kasar Ransum dengan Berbagai Level Bagasse secara In Sacco

This research was conducted to determine in sacco degradability of dry matter, organic matter and crude fiber in ration with different levels of bagasse and determine the best level of bagasse in ruminant ration from degradability. The research is expected to give information about the best level of bagasse as a source of crude fiber in the complete feed views of degradability of dry matter, organic matter and crude fiber. Research conducted at the Laboratory of Animal Feed Faculty of Animal Husbandry and Agriculture Diponegoro University Semarang from October 2011 to February 2012. The research was conducted by using a three Jawa Randu Goat which fistulated on rumen as replication. The treatment are T1 = ration level of 25% bagasse, T2 = bagasse rations with 30% level, T3 = ration with the level of 35% bagasse and T4 = bagasse rations with 40% level. Ration degradability measured by using in Sacco method. The variables measured were percent loss of DM, OM and CF to calculate the fraction of a, b, c and degradation theory (DT) dry matter, organic matter and crude fiber. To calculate the degradation of feed at a time "t" (DT) used the exponential equation P = a + b (1 – exp-ct). Fraction of the value of a, b, c and DT were then analyzed statistically based on completely randomized design (CRD) if there is a treatment effect, followed by Duncan's Multiple Range Test (DMRT) for difference between means. The analysis of variance showed that there was significant effect (P <0.05) between the fraction of easily degradable (a) DM, OM and CF, and degradation theory (DT) DM, OM and CF, therefore the potentially degradable fraction (b) DM, OM and CF, the degradation rate of potentially degradable fraction (c) DM, OM and CF showed no real difference

Analizar el Comportamiento Innovador de Telares “El Chile” en el Municipio de San Dionisio, Departamento de Matagalpa durante el segundo semestre del año 2016

El tema sobre el cual se desarrolló esta investigación, tiene el objetivo de analizar el Comportamiento Innovador de las PYMES durante el periodo del 2016. En donde se describe tanto el Comportamiento Innovador Proactivo y Reactivo de Telares “El Chile”, se explican los beneficios que se logran cuando se realizan innovaciones, identificando el desarrollo de las PYMES por las innovaciones realizadas, para valorar posteriormente su tendencia después de haber efectuados cambios o mejoras en los diferentes procesos utilizados por la empresa. Las innovaciones son elementos claves en el desarrollo empresarial, ya que constituye uno de los factores más importantes en el aumento de la productividad y obtener ventajas competitivas, lo que es fundamental en las empresas para su crecimiento. Sin embargo, todos los beneficios que facilitan las innovaciones se desaprovecharían, si los empresarios de PYMES no cumplen con el requisito principal para innovar, que es el desarrollo de la capacidad de observación y sensibilidad para detectar y/o anticipar necesidades, expectativas o deseos de sus clientes. Con base en los resultados obtenidos, se encontró que están adoptando un Comportamiento Innovador que en mayor proporción es Proactivo que Reactivo, ya que las innovaciones inciden de forma directa, en cuanto al aumento de productividad y de crecimiento empresarial, aunque existen innovaciones que no son aplicables a la pequeña empresa, debido a las restricciones que la limitan para alcanzarla, siendo la económica para muchas empresas. De cierta forma, la gerencia de Telares “El Chile” desconoce los beneficios que se alcanzan al realizar cambios o mejoras en la empresa, impidiendo a los que tienen ideas innovadoras poderlas experimenta

Pengembangan Model Pembelajaran Matematika Berbasis Flipped Classroom Pada Siswa Kelas XI SMKN 1 Gedangsari Gunungkidul

The aim of the research was developed of mathematic theaching model based Flipped Classroom. The final result of the research is to tasted the effectiveness of mathematic theaching model based Flipped Classroom. The research method is Research and development that includes introduction, field study of theaching management in the school, planning and preparing Flipped Classroom model, implementation of theaching firs cycle, second cycle, and third cycle, and exam of attitude, skill, and learning outcome. The result of the study was mathematic teaching model based Flipped Classroom at the eleven grade student of SMKN 1 Gedangsari Gunungkidul can maximize the time of theaching the classroom by maximizing the direct instruction and interaction one by one through teaching video that was uploaded in online or offline. The teaching material divided into two types, they were teaching video from ck-12.org site and original materials that were made by the students. Mathematic theaching model based Flipped Classroom used Problem Based Learning (PBL) method in the first and second cycle, while in the third cycle used Discovery Learning (DL) method for increasing creativity, responsibility, and skill of study. The effectiveness of the model was used covariance analysis test (ankova). It shows that the level of significant was smaller from 0,05 to 0,00. The effectiveness of the attitude, skill, and learning outcome was used Mann-Whitney non parametric analysis. It shows that level of significant was smaller from 0,005 to 0,003; 0,008; 0,009. The researcher concluded that the implementation of mathematic teaching model based Flipped Classroom at the eleventh grade students of SMKN 1 Gedangsari Gunungkidul was effective

Adding value to laboratory medicine: a professional responsibility

Laboratory medicine is a medical specialty at the centre of healthcare. When used optimally laboratory medicine generates knowledge that can facilitate patient safety, improve patient outcomes, shorten patient journeys and lead to more cost-effective healthcare. Optimal use of laboratory medicine relies on dynamic and authoritative leadership outside as well as inside the laboratory. The first responsibility of the head of a clinical laboratory is to ensure the provision of a high quality service across a wide range of parameters culminating in laboratory accreditation against an international standard, such as ISO 15189. From that essential baseline the leadership of laboratory medicine at local, national and international level needs to ‘add value’ to ensure the optimal delivery, use, development and evaluation of the services provided for individuals and for groups of patients. A convenient tool to illustrate added value is use of the mnemonic ‘SCIENCE’. This tool allows added value to be considered in seven domains: standardisation and harmonisation; clinical effectiveness; innovation; evidence-based practice; novel applications; cost-effectiveness; and education of others. The assessment of added value in laboratory medicine may be considered against a framework that comprises three dimensions: operational efficiency; patient management; and patient behaviours. The profession and the patient will benefit from sharing examples of adding value to laboratory medicine

The Slottsmøya marine reptile Lagerstätte: depositional environments, taphonomy and diagenesis

The Late Jurassic Slottsmøya Member Lagerstätte on Spitsbergen offers a unique opportunity to study the relationships between vertebrate fossil preservation, invertebrate occurrences and depositional environment. In this study, 21 plesiosaurian and 17 ichthyosaur specimens are described with respect to articulation, landing mode, preservation, and possible predation and scavenging. The stratigraphic distribution of marine reptiles in the Slottsmøya Member is analysed, and a correlation between high total organic content, low oxygen levels, few benthic invertebrates and optimal reptile preservation is observed. A new model for 3D preservation of vertebrates in highly compacted organic shales is explained

Prospective comparative study of ERCP brush cytology and EUS-FNA for the diferential diagnosis of biliary strictures

OBJECTIVE: To evaluate and to compare the diagnostic yield of ERCP brush cytology (ERCP) and EUS-FNA in patients with biliary strictures and evaluates the agreement between general pathologists (GP) and expert GI pathologists (GIP) in the final diagnosis of biliary strictures. METHODS: Patients with biliary strictures documented by ERCP were included. Brush cytology was performed and during EUS, only visible mass lesions or localized bile duct wall thickening were aspirated. The gold standard method for diagnosis was surgical histology and/or follow-up. Tissue sampling results were: malignant, suspicious, atypical, insufficiently or benign. Specimens were interpreted by GP and GIP, blinded for prior tests results. RESULTS: 46 patients were included. Final diagnosis was malignancy in 37 (26 pancreatic - 11 biliary) and benign in 9 (8 chronic pancreatitis - 1 common bile duct inflammatory stricture). Sensitivity and accuracy for ERCP brush cytology were 43.2% and 52.2% for GP and 51.4% and 58.7% for GIP. Sensitivity and accuracy for EUS-FNA were 52.8% and 58.5%, respectively for GP and 69.4% e 73.2% for GIP. In comparison, the combination of brush cytology and EUS-FNA demonstrated higher sensitivity and accuracy for both GP (64.9% and 69.6%, respectively) and GIP (83.8% and 84.8%, respectively) and improved agreement with final diagnosis for both (mostly for GIP). CONCLUSION: Both, ERCP brush cytology and EUS-FNA has a similar yield for the diagnosis of biliary strictures. However, the combination of these methods results in an improved diagnostic accuracy. In addition, GIP might be expected to interpret specimens with greater accuracy than GP.OBJETIVO: Avaliar o desempenho diagnóstico da citologia obtida pela CPER, aquele obtido pela EE-PAAF e a concordância entre patologistas gerais (PG) e especialistas (PE) em pacientes com estenose biliar. MÉTODOS: Incluímos pacientes com estenose biliar identificados pela CPER. A EE-PAAF foi realizada apenas em áreas com efeito de massa ou da parede espessada do ducto biliar. O padrão-ouro foi a cirurgia, histologia e/ou o seguimento. As amostras teciduais foram consideradas: malignas, suspeitas, atípicas, insuficientes ou benignas. Os espécimes obtidos por cada método foi interpretado (cego) por um PG e outro PE. RESULTADO: 46 pacientes foram incluídos (37 malignos e 9 benignos). O diagnóstico final foi de tumor pancreático (26), biliar (11), pancreatite crônica (8) e estenose inflamatória do ducto biliar (1). Sensibilidade e acurácia da CPER foram 43,2% e 52,2% para o PG e 51,4% e 58,7% para o PE. Sensibilidade e acurácia da EE-PAAF foi 52,8% e 58,5% para o PG e 69,4% e 73,2% para o PE. A combinação entre a CPER e EE-PAAF demonstrou maior sensibilidade e acurácia para ambos PG (64,9% e 69,6%) e PE (83,8% e 84,8%), respectivamente. CONCLUSÃO: A citologia obtida pelo escovado da via biliar durante a CPER e as amostras teciduais colhidas pela EE-PAAF tem rendimento semelhante para o diagnóstico das estenoses biliares. No entanto, a combinação dos métodos resulta em uma maior acurácia. Além disso, espera-se que a interpretação das amostras ocorra com maior precisão pelo PE se comparado ao PG.Universidade de São Paulo Faculdade de Medicina de Ribeirão Preto Departamento de Cirurgia e AnatomiaUniversidade Federal de São Paulo (UNIFESP) Unidade de Diagnóstico AnatomopatológicoUNIFESP, Unidade de Diagnóstico AnatomopatológicoSciEL

Prevalence and risk factors for Human T-Lymphotropic Virus Type 1 (HTLV-1) among maintenance hemodialysis patients

BACKGROUND: Infection with the human T-cell lymphotropic virus type 1 (HTLV-1), although asymptomatic in most cases, can lead to potentially grave consequences, such as adult T-cell leukemia-lymphoma and HTLV-1-associated myelopathy / tropical spastic paraparesis. Its prevalence varies widely across different populations and geographic regions. A population-based study in the city of Salvador, located in the Northeast region of Brazil, showed an overall prevalence of HTLV-1 seropositivity of 1.7%. Blood borne virus infections are recognized as important hazards for patients and staff in maintenance hemodialysis (MHD) units but most studies focus on hepatitis B, hepatitis C and human immunodeficiency viruses. There are scarce data about HTLV-1 infection in the MHD population. We aimed to determine the prevalence and risk factors for HTLV-1 infection among MHD patients in the city of Salvador-Bahia, Brazil. METHODS: We conducted a multi-center, cross-sectional study nested in a prospective cohort of MHD patients enrolled from four outpatient clinics. HTLV-1 screening was performed with ELISA and positive cases were confirmed by Western Blot. Factors associated with HTLV-1 seropositivity were identified by multivariable logistic regression. RESULTS: 605 patients were included in the study. The overall prevalence of HTLV-1 infection was 2.48% (15/605), which was similar to that of hepatitis B [1.98% (12/605)] and C [3.14% (19/605)] viruses in our sample. HTLV-1 seropositivity was positively associated with age [prevalence odds ratio (POR) 1.04; 95% confidence interval (CI) 1.01–1.08], unmarried status (POR 3.65; 95% CI 1.13–11.65), and history of blood transfusion (POR 3.35; 95% CI 1.01–11.13). CONCLUSIONS: The overall prevalence of HTLV-1 infection in a sample of MHD patients was similar to that of other viral infections, such as hepatitis B and C. Our data revealed that MHD patients who are older, unmarried or who have received blood transfusions are at higher risk for HTLV-1 infection

Microbial community composition of transiently wetted Antarctic Dry Valley soils

During the summer months, wet (hyporheic) soils associated with ephemeral streams and lake edges in the Antarctic Dry Valleys (DVs) become hotspots of biological activity and are hypothesized to be an important source of carbon and nitrogen for arid DV soils. Recent research in the DV has focused on the geochemistry and microbial ecology of lakes and arid soils, with substantially less information being available on hyporheic soils. Here, we determined the unique properties of hyporheic microbial communities, resolved their relationship to environmental parameters and compared them to archetypal arid DV soils. Generally, pH increased and chlorophyll a concentrations decreased along transects from wet to arid soils (9.0 to ~7.0 for pH and ~0.8 to ~5 μg/cm3 for chlorophyll a, respectively). Soil water content decreased to below ~3% in the arid soils. Community fingerprinting-based principle component analyses revealed that bacterial communities formed distinct clusters specific to arid and wet soils; however, eukaryotic communities that clustered together did not have similar soil moisture content nor did they group together based on sampling location. Collectively, rRNA pyrosequencing indicated a considerably higher abundance of Cyanobacteria in wet soils and a higher abundance of Acidobacterial, Actinobacterial, Deinococcus/Thermus, Bacteroidetes, Firmicutes, Gemmatimonadetes, Nitrospira, and Planctomycetes in arid soils. The two most significant differences at the genus level were Gillisia signatures present in arid soils and chloroplast signatures related to Streptophyta that were common in wet soils. Fungal dominance was observed in arid soils and Viridiplantae were more common in wet soils. This research represents an in-depth characterization of microbial communities inhabiting wet DV soils. Results indicate that the repeated wetting of hyporheic zones has a profound impact on the bacterial and eukaryotic communities inhabiting in these areas

Safety and effectiveness of a new toric presbyopia-correcting posterior chamber silicone intraocular lens.

PURPOSE: To evaluate the safety and effectiveness of the Trulign toric intraocular lens (IOL) in adults with cataract. SETTING: Eight private practices in the United States and 1 in Canada. DESIGN: Prospective randomized single-masked multicenter study. METHODS: A toric IOL (1.25 D, 2.00 D, or 2.75 D, determined by a toric calculator) was implanted in eligible patients with age-related cataract requiring a 16.00 to 27.00 diopter (D) spherical IOL power and with a predicted postoperative astigmatism of 0.83 to 2.50 D. Eyes within the lowest cylinder range (predicted postoperative astigmatism 0.83 to 1.32 D) were randomized in a 1:1 ratio between the 1.25 D toric IOL group and the nontoric accommodating IOL (Crystalens) control group. RESULTS: The toric 1.25 D group had a statistically significantly greater percentage reduction in absolute cylinder (P < .001) and uncorrected distance visual acuity (P = .002) than the control group at the 120- to 180-day visit. The mean monocular uncorrected vision at distance, intermediate, and near was 20/25, 20/22, and 20/39, respectively, with the 1.25 D, 2.00 D, and 2.75 D toric IOLs in aggregate (toric group). In addition, 96.1% of patients (123/128) had 5.0 degrees or less absolute IOL rotation postoperatively. Regarding safety, the endpoints for preservation of corrected visual acuity and the incidence of complications and adverse events were met. CONCLUSION: The toric IOL was safe and effective in reducing the effects of preoperative corneal astigmatism and provided excellent uncorrected distance and intermediate vision and functional near vision. FINANCIAL DISCLOSURES: Dr. Pepose is a consultant to Bausch & Lomb and was medical monitor of this study. Drs. Buckhurst, Whitman, Feinerman, Hovanesian, Davies, Labor, and Carter are consultants to Bausch & Lomb. At the time of the study, Drs. Hayashida, and Khodai were employees of Bausch & Lomb. Drs. Colvard and Mittleman have financial or proprietary interest in any material or method mentioned

KEMAMPUAN PELAFALAN BAHASA MANDARIN MAHASISWA SEMESTER III PROGRAM STUDI BAHASA DAN SASTRA CINA FAKULTAS ILMU BUDAYA UNIVERSITAS BRAWIJAYA

Kata Kunci : Pelafalan, Nada, Vokal, Konsonan. Fonologi adalah kajian linguistik yang mempelajari bunyi bahasa. Pelafalan Bahasa Mandarin ada 3 yaitu Konsonan (21), Vokal (37) dan Nada (4). Di dalam Bahasa Mandarin ada 4 nada yang berbeda, arti yang berbeda dan tulisan yang berbeda. Dalam skripsi ini, penulis tertarik membahas tentang kemampuan pelafalan Bahasa Mandarin mahasiswa Semester III. Hal tersebut untuk menjawab rumusan masalah dan tujuan yakni kemampuan dan deskripsi kesalahan yang dilakukan oleh mahasiswa Semester III melafalkan fonem Bahasa Mandarin. Penelitian ini menggunakan metode deskriptif kuantitatif. Dari hasil penelitian diketahui bahwa beberapa mahasiswa dapat melafalkan fonem Bahasa Mandarin dengan lancar dan beberapa mahasiswa kurang lancar dalam melafalkan fonem Bahasa Mandarin. Penulis menyarankan agar penelitian selanjutnya tetap menggunakan objek yaitu mahasiswa dengan konsep pelafalan yang berbeda, sehingga penjelasan sertapenelitian tentang pelafalan lebih beragam