309 research outputs found

    Hocking's philosophy of the human self.

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    Thesis (Ph.D.)--Boston University

    Sensing and Active Flow Control for Advanced BWB Propulsion-Airframe Integration Concepts

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    In order to realize the substantial performance benefits of serpentine boundary layer ingesting diffusers, this study investigated the use of enabling flow control methods to reduce engine-face flow distortion. Computational methods and novel flow control modeling techniques were utilized that allowed for rapid, accurate analysis of flow control geometries. Results were validated experimentally using the Techsburg Ejector-based wind tunnel facility; this facility is capable of simulating the high-altitude, high subsonic Mach number conditions representative of BWB cruise conditions

    On the dynamics of planetesimals embedded in turbulent protoplanetary discs with dead zones

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    (abridged) Accretion in protoplanetary discs is thought to be driven by [...] turbulence via the magnetorotational instability (MRI). Recent work has shown that a planetesimal swarm embedded in a fully turbulent disc is subject to strong excitation of the velocity dispersion, leading to collisional destruction of bodies with radii R_p < 100 km. Significant diffusion of planetesimal semimajor axes also arises, leading to large-scale spreading of the planetesimal population throughout the inner regions of the protoplanetary disc, in apparent contradiction of constraints provided by the distribution of asteroids within the asteroid belt. In this paper, we examine the dynamics of planetesimals embedded in vertically stratified turbulent discs, with and without dead zones. Our main aims are to examine the turbulent excitation of the velocity dispersion, and the radial diffusion, of planetesimals in these discs. We employ three dimensional MHD simulations [...], along with an equilibrium chemistry model [...] We find that planetesimals in fully turbulent discs develop large random velocities that will lead to collisional destruction/erosion for bodies with sizes below 100 km, and undergo radial diffusion on a scale \sim 2.5 au over a 5 Myr disc life time. But planetesimals in a dead zone experience a much reduced excitation of their random velocities, and equilibrium velocity dispersions lie between the disruption thresholds for weak and strong aggregates for sizes R_p < 100 km. We also find that radial diffusion occurs over a much reduced length scale \sim 0.25 au over the disc life time, this being consistent with solar system constraints. We conclude that planetesimal growth via mutual collisions between smaller bodies cannot occur in a fully turbulent disc. By contrast, a dead zone may provide a safe haven in which km-sized planetesimals can avoid mutual destruction through collisions.Comment: 18 pages, 13 figures, 3 tables, MNRAS in press, minor corrections to match the published versio

    Historical trends in iodine and selenium in soil and herbage at the Park Grass experiment, Rothamsted Research, UK

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    Long term trends in iodine and selenium retention in soil, and uptake by herbage, were investigated in archived samples from the Park Grass Experiment, initiated in 1856 at Rothamsted, UK. Soil (0-23 cm) and herbage samples from plots receiving various mineral fertilisers and organic manures, with and without lime, were analysed for Se and iodine (I) to assess the effect of soil amendment, annual rainfall, crop yield and changes in soil chemistry from 1876 to 2008. Comparing soil from limed and un-limed control (unfertilized) plots, TMAH-extractable Se and I concentrations both diverged, with time, with greater retention in un-limed plots; differences in concentration amounted to 92 and 1660 µg kg-1 for Se and I respectively after 105 yr. These differences were broadly consistent with estimated additions from rainfall and dry deposition. Offtake of both elements in herbage was negligible compared to soil concentrations and annual inputs (<0.003% of total soil I and <0.006% of total soil Se). A positive correlation was observed between I and Se concentrations in herbage, suggesting some common factors controlling bioavailability. A growth-dilution effect for I and Se was suggested by the positive correlation between growing season rainfall (GSR) and herbage yield together with soil-to-plant transfer factors decreasing with yield. Phosphate and sulphate fertilizers reduced I and Se herbage concentrations, both through ion competition and increased herbage yield. Results suggest that in intensive agriculture with soil pH control, the I requirement of grazing animals is not likely to be met by herbage alone

    Seasonal flows of international British Columbia-Alaska rivers: The nonlinear influence of ocean-atmosphere circulation patterns

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    The northern portion of the Pacific coastal temperate rainforest (PCTR) is one of the least anthropogenically modified regions on earth and remains in many respects a frontier area to science. Rivers crossing the northern PCTR, which is also an international boundary region between British Columbia, Canada and Alaska, USA, deliver large freshwater and biogeochemical fluxes to the Gulf of Alaska and establish linkages between coastal and continental ecosystems. We evaluate interannual flow variability in three transboundary PCTR watersheds in response to El Niño-Southern Oscillation (ENSO), Pacific Decadal Oscillation (PDO), Arctic Oscillation (AO), and North Pacific Gyre Oscillation (NPGO). Historical hydroclimatic datasets from both Canada and the USA are analyzed using an up-to-date methodological suite accommodating both seasonally transient and highly nonlinear teleconnections. We find that streamflow teleconnections occur over particular seasonal windows reflecting the intersection of specific atmospheric and terrestrial hydrologic processes. The strongest signal is a snowmelt-driven flow timing shift resulting from ENSO- and PDO-associated temperature anomalies. Autumn rainfall runoff is also modulated by these climate modes, and a glacier-mediated teleconnection contributes to a late-summer ENSO-flow association. Teleconnections between AO and freshet flows reflect corresponding temperature and precipitation anomalies. A coherent NPGO signal is not clearly evident in streamflow. Linear and monotonically nonlinear teleconnections were widely identified, with less evidence for the parabolic effects that can play an important role elsewhere. The streamflow teleconnections did not vary greatly between hydrometric stations, presumably reflecting broad similarities in watershed characteristics. These results establish a regional foundation for both transboundary water management and studies of long-term hydroclimatic and environmental change

    Three-dimensional dielectric photonic crystal structures for laser-driven acceleration

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    We present the design and simulation of a three-dimensional photonic crystal waveguide for linear laser-driven acceleration in vacuum. The structure confines a synchronous speed-of-light accelerating mode in both transverse dimensions. We report the properties of this mode, including sustainable gradient and optical-to-beam efficiency. We present a novel method for confining a particle beam using optical fields as focusing elements. This technique, combined with careful structure design, is shown to have a large dynamic aperture and minimal emittance growth, even over millions of optical wavelengths

    Learning to Detect Touches on Cluttered Tables

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    We present a novel self-contained camera-projector tabletop system with a lamp form-factor that brings digital intelligence to our tables. We propose a real-time, on-device, learning-based touch detection algorithm that makes any tabletop interactive. The top-down configuration and learning-based algorithm makes our method robust to the presence of clutter, a main limitation of existing camera-projector tabletop systems. Our research prototype enables a set of experiences that combine hand interactions and objects present on the table. A video can be found at https://youtu.be/hElC_c25Fg8

    Chlorpromazine versus placebo for schizophrenia

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    Prevalence of a history of prior varicella/herpes zoster infection in multiple sclerosis

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    Varicella zoster virus (VZV) infection has been implicated in multiple sclerosis (MS), but direct causal involvement has been disputed. Nevertheless, knowledge of VZV exposure is important, given the risk of serious complications of first exposure while undergoing immunosuppressive treatment, in particular with fingolimod. We distributed questionnaires to MS clinic patients, requesting information about history of chickenpox, sibling/household/occupational exposure, history of zoster (shingles), and disease-modifying treatment. A random, proportionally representative sample of 51 patients that included patients with positive, negative, and unknown chickenpox history were selected for determination of VZV IgG by ELISA. Of 1206 distributed questionnaires, 605 were returned (50% response rate). Of these, 86% reported history of chickenpox, 5.6% gave negative history, and 8.5% did not know. Of 594 who answered the zoster question, 78% gave a negative response, 4% did not know, and 104 (17%) answered yes. Of these, 83 reported 1 episode; 12 had 2; 5 had 3; and 1 each reported 5, 6, and 15 episodes. Of 51 patients tested for VZV IgG (44 “yes,” 4 “no,” and 3 “I don’t know” answers to the question of whether they had chickenpox), 48 were seropositive; the 3 seronegative all had reported having had chickenpox. The high rate of MS patients reporting prior chickenpox infection is comparable with previous reports. A substantial proportion of MS patients, estimated to be higher than an age-matched general population, report single or multiple episodes of zoster. These data are useful for consideration of immunosuppressive treatments and/or VZV and zoster vaccination

    A Simplified Method to Distinguish Farmed (Salmo salar) from Wild Salmon: Fatty Acid Ratios Versus Astaxanthin Chiral Isomers

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    Mislabeling of farmed and wild salmon sold in markets has been reported. Since the fatty acid content of fish may influence human health and thus consumer behavior, a simplified method to identify wild and farmed salmon is necessary. Several studies have demonstrated differences in lipid profiles between farmed and wild salmon but no data exists validating these differences with government-approved methods to accurately identify the origin of these fish. Current methods are both expensive and complicated, using highly specialized equipment not commonly available. Therefore, we developed a testing protocol using gas chromatography (GC), to determine the origin of salmon using fatty acid profiles. We also compared the GC method with the currently approved FDA (United States Food and Drug Administration) technique that uses analysis of carotenoid optical isomers and found 100% agreement. Statistical validation (n = 30) was obtained showing elevated 18:2n-6 (z = 4.56; P = 0.0001) and decreased 20:1n-9 (z = 1.79; P = 0.07) in farmed samples. The method is suitable for wide adaptation because fatty acid methyl ester analysis is a well-established procedure in labs that conduct analysis of lipid composition and food constituents. GC analysis for determining the origin of North American salmon compared favorably with the astaxanthin isomer technique used by the FDA and showed that the fatty acid 18:2n-6 was the key indicator associated with the origin of these salmon
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