782 research outputs found
Distance to first symptoms measured by the 6-min walking test differentiates between treatment success and failure in patients with degenerative lumbar disorders
PURPOSE
The smartphone-based 6-min walking test (6WT) is an established digital outcome measure in patients undergoing surgery for degenerative lumbar disorders (DLD). In addition to the 6WTs primary outcome measure, the 6-min walking distance (6WD), the patient's distance to first symptoms (DTFS) and time to first symptoms (TTFS) can be recorded. This is the first study to analyse the psychometric properties of the DTFS and TTFS.
METHODS
Forty-nine consecutive patients (55 ± 15.8 years) completed the 6WT pre- and 6 weeks (W6) postoperative. DTFS and TTFS were assessed for reliability and content validity using disease-specific patient-reported outcome measures. The Zurich Claudication Questionnaire patient satisfaction subscale was used as external criterion for treatment success. Internal and external responsiveness for both measures at W6 was evaluated.
RESULTS
There was a significant improvement in DTFS and TTFS from baseline to W6 (p < 0.001). Both measures demonstrated a good test-retest reliability (β = 0.86, 95% CI 0.81-0.90 and β = 0.83, 95% CI 0.76-0.87, both p < 0.001). The DTFS exceeded the 6WD capability to differentiate between satisfied (82%) and unsatisfied patients (18%) with an AUC of 0.75 (95% CI 0.53-0.98) vs. 0.70 (95% CI 0.52-0.90). The TTFS did not demonstrate meaningful discriminative abilities.
CONCLUSION
Change in DTFS can differentiate between satisfied and unsatisfied patients after spine surgery. Digital outcome measures on the 6WT metric provide spine surgeons and researchers with a mean to assess their patient's functional disability and response to surgical treatment in DLD
Identification of the major active ingredients in illegal pesticide seized by Brazilian Federal Police and quantification of metsulfuron-methyl and tebuconazole
A compilação de relatórios forenses de agrotóxicos, objetos de apreensões pela PolÃcia Federal no Brasil, mostrou que metsulfurom-metÃlico, imidacloprido, fipronil, tebuconazol, clorimurom-etÃlico e glifosato são os principais ingredientes ativos (IA) importados ilegalmente. Apesar destes IA não estarem entre os agrotóxicos mais comercializados no paÃs, o alto preço das formulações correspondentes legalmente registradas pode estimular esta atividade ilegal. Com base neste estudo, amostras de agrotóxicos contrabandeados apreendidos contendo tebuconazol e metsulfurom-metÃlico foram analisadas quantitativamente utilizando cromatografia a gás e lÃquida, respectivamente. Tebuconazol, em apresentações lÃquidas e sólidas, apresentou concentrações concordantes com as informações dos rótulos, enquanto que a maioria das amostras de metsulfurom-metÃlico, rotuladas como 600 g kg-1, apresentaram concentrações mais baixas nas análises quÃmicas (média de 337,0 g kg-1 + 2,0).The compilation of forensic reports from pesticides seized by the Federal Police in Brazil showed that metsulfuron-methyl, imidacloprid, fipronil, tebuconazole, clorimuron-ether and glyphosate were the dominant active ingredients (AI) illegally imported. Despite these AI were not among the most traded pesticides in Brazil, high prices of corresponding legal formulations may stimulate this illegal activity. Based on this study, smuggled pesticides containing tebuconazole and metsulfuron-methyl were seized and quantitatively analyzed using gas and liquid chromatography, respectively. Tebuconazole results, in liquid and solid presentations, were in accordance with the information on the label, while most metsulfuron-methyl samples, labeled as 600 g kg-1, showed lower concentrations in chemical analysis (mean of 337.0 g kg-1 + 2.0)
Qualidade fisiológica de sementes de quinoa produzidas no sul do rio grande do sul, em função da ordem das hastes florais.
Produção de sementes de quinoa no sul do Brasil: variabilidade de plantas da cultivar BRS Piabiru.
The MuPix high voltage monolithic active pixel sensor for the Mu3e experiment
Mu3e is a novel experiment searching for charged lepton flavor violation in the rare decay . In order to reduce background by up to 16 orders of magnitude, decay vertex position, decay time and particle momenta have to be measured precisely. A pixel tracker based on 50mm thin high voltage monolithic active pixel sensors (HV-MAPS) in a magnetic field will deliver precise vertex and momentum information. Test beam results like an excellent efficiency of > 99:5% and a time resolution of better than 16.6 ns obtained with the MuPix HV-MAPS chip developed for the Mu3e pixel tracker are presented
Feasibility studies of time-like proton electromagnetic form factors at PANDA at FAIR
Simulation results for future measurements of electromagnetic proton form
factors at \PANDA (FAIR) within the PandaRoot software framework are reported.
The statistical precision with which the proton form factors can be determined
is estimated. The signal channel is studied on the basis
of two different but consistent procedures. The suppression of the main
background channel, , is studied.
Furthermore, the background versus signal efficiency, statistical and
systematical uncertainties on the extracted proton form factors are evaluated
using two different procedures. The results are consistent with those of a
previous simulation study using an older, simplified framework. However, a
slightly better precision is achieved in the PandaRoot study in a large range
of momentum transfer, assuming the nominal beam conditions and detector
performance
Observation of in
Using a sample of events recorded with
the BESIII detector at the symmetric electron positron collider BEPCII, we
report the observation of the decay of the charmonium state
into a pair of mesons in the process
. The branching fraction is measured for the first
time to be , where the first uncertainty is
statistical, the second systematic and the third is from the uncertainty of
. The mass and width of the are
determined as MeV/ and
MeV.Comment: 13 pages, 6 figure
Observation and study of the decay
We report the observation and study of the decay
using events
collected with the BESIII detector. Its branching fraction, including all
possible intermediate states, is measured to be
. We also report evidence for a structure,
denoted as , in the mass spectrum in the GeV/
region. Using two decay modes of the meson ( and
), a simultaneous fit to the mass spectra is
performed. Assuming the quantum numbers of the to be , its
significance is found to be 4.4, with a mass and width of MeV/ and MeV, respectively, and a
product branching fraction
. Alternatively, assuming , the
significance is 3.8, with a mass and width of MeV/ and MeV, respectively, and a product
branching fraction
. The angular distribution of
is studied and the two assumptions of the
cannot be clearly distinguished due to the limited statistics. In all
measurements the first uncertainties are statistical and the second systematic.Comment: 10 pages, 6 figures and 4 table
First observations of hadrons
Based on events collected with
the BESIII detector, five hadronic decays are searched for via process
. Three of them, ,
, and are observed for the first
time, with statistical significances of 7.4, , and
9.1, and branching fractions of ,
, and ,
respectively, where the first uncertainties are statistical and the second
systematic. No significant signal is observed for the other two decay modes,
and the corresponding upper limits of the branching fractions are determined to
be and at 90% confidence level.Comment: 17 pages, 16 figure
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