Emission of gamma rays shifted from resonant absorption by electron-nuclear double transitions in ^{151}Eu^{2+}:CaF_2

We show that the emission of a gamma-ray photon by a nucleus can be influenced by a microwave magnetic field acting on the atomic electrons. We study theoretically these electron-nuclear double transitions (ENDTs) for ^{151}Eu nuclei in a CaF_2 lattice at low temperature, in the presence of a static magnetic field and of a microwave magnetic field. The ENDTs acquire a significant intensity for certain resonance frequencies. The ENDTs are of interest for the identification of the position of the lines in complex M\"{o}ssbauer spectra.Comment: 8 pages; 3 Postscript figures: Fig. 1, Fig. 2(a), Fig. 2(b

The O I] 1641A line as a probe of symbiotic star winds

The neutral oxygen resonance 1302A line can, if the optical depth is sufficiently high, de-excite by an intercombination transition at 1641A to a metastable state. This has been noted in a number of previous studies but never systematically investigated as a diagnostic of the neutral red giant wind in symbiotic stars and symbiotic-like recurrent novae. We used archival $IUE$ high resolution, and GHRS and STIS medium and high resolution, spectra to study a sample of symbiotic stars. The integrated fluxes were measured, where possible, for the O I 1302A and O I] 1641A lines. The intercombination 1641A line is detected in a substantial number of symbiotic stars with optical depths that give column densities comparable with direct eclipse measures (EG And) and the evolution of the recurrent nova RS Oph 1985 in outburst. In four systems (EG And, Z And, V1016 Cyg, and RR Tel), we find that the O I] variations are strongly correlated with the optical light curve and outburst activity. This transition can also be important for the study of a wide variety of sources in which an ionization-bounded H II region is imbedded in an extensive neutral medium, including active galactic nuclei, and not only for evaluations of extinction.Comment: accepted for publication in Astronomy and Astrophysics (2010 Feb. 23), in press, NASA-GSFC-Code 66

TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis

Severe sepsis is often accompanied by acute kidney injury (AKI) and albuminuria. Here we studied whether the AKI and albuminuria associated with lipopolysaccharide (LPS) treatment in mice reflects impairment of the glomerular endothelium with its associated endothelial surface layer. LPS treatment decreased the abundance of endothelial surface layer heparan sulfate proteoglycans and sialic acid, and led to albuminuria likely reflecting altered glomerular filtration perm-selectivity. LPS treatment decreased the glomerular filtration rate (GFR), while also causing significant ultrastructural alterations in the glomerular endothelium. The density of glomerular endothelial cell fenestrae was 5-fold lower whereas the average fenestrae diameter was 3-fold higher in LPS-treated than in control mice. The effects of LPS on the glomerular endothelial surface layer, endothelial cell fenestrae, GFR, and albuminuria were diminished in TNF receptor 1 (TNFR1) knockout mice, suggesting that these LPS effects are mediated by TNF-α activation of TNFR1. Indeed, intravenous administration of TNF decreased GFR and led to loss of glomerular endothelial cell fenestrae, increased fenestrae diameter, and damage to the glomerular endothelial surface layer. LPS treatment decreased kidney expression of vascular endothelial growth factor (VEGF). Thus, our findings confirm the important role of glomerular endothelial injury, possibly by a decreased VEGF level, in the development and progression of AKI and albuminuria in the LPS model of sepsis in the mouse

Supervised classification of landforms in Arctic mountains

Erosional and sediment fluxes from Arctic mountains are lower than for temperate mountain ranges due to the influence of permafrost on geomorphic processes. As permafrost extent declines in Arctic mountains, the spatial distribution of geomorphic processes and rates will change. Improved access to high‐quality remotely sensed topographic data in the Arctic provides an opportunity to develop our understanding of the spatial distribution of Arctic geomorphological processes and landforms. Utilizing newly available Arctic digital topography data, we have developed a method for geomorphic mapping using a pixel‐based linear discriminant analysis method that could be applied across Arctic mountains. We trained our classifier using landforms within the Adventdalen catchment in Svalbard and applied it to two adjacent catchments and one in Alaska. Slope gradient, elevation–relief ratio and landscape roughness distinguish landforms to a first order with >80% accuracy. Our simple classification system has a similar overall accuracy when compared across our field sites. The simplicity and robustness of our classification suggest that it is possible to use it to understand the distribution of Arctic mountain landforms using extant digital topography data and without specialized classifications. Our preliminary assessments of the distribution of geomorphic processes within these catchments demonstrate the importance of post‐glacial hillslope processes in governing sediment movement in Arctic mountains

SCAMP:standardised, concentrated, additional macronutrients, parenteral nutrition in very preterm infants: a phase IV randomised, controlled exploratory study of macronutrient intake, growth and other aspects of neonatal care

<p>Abstract</p> <p>Background</p> <p>Infants born <29 weeks gestation are at high risk of neurocognitive disability. Early postnatal growth failure, particularly head growth, is an important and potentially reversible risk factor for impaired neurodevelopmental outcome. Inadequate nutrition is a major factor in this postnatal growth failure, optimal protein and calorie (macronutrient) intakes are rarely achieved, especially in the first week. Infants <29 weeks are dependent on parenteral nutrition for the bulk of their nutrient needs for the first 2-3 weeks of life to allow gut adaptation to milk digestion. The prescription, formulation and administration of neonatal parenteral nutrition is critical to achieving optimal protein and calorie intake but has received little scientific evaluation. Current neonatal parenteral nutrition regimens often rely on individualised prescription to manage the labile, unpredictable biochemical and metabolic control characteristic of the early neonatal period. Individualised prescription frequently fails to translate into optimal macronutrient delivery. We have previously shown that a standardised, concentrated neonatal parenteral nutrition regimen can optimise macronutrient intake.</p> <p>Methods</p> <p>We propose a single centre, randomised controlled exploratory trial of two standardised, concentrated neonatal parenteral nutrition regimens comparing a standard macronutrient content (maximum protein 2.8 g/kg/day; lipid 2.8 g/kg/day, dextrose 10%) with a higher macronutrient content (maximum protein 3.8 g/kg/day; lipid 3.8 g/kg/day, dextrose 12%) over the first 28 days of life. 150 infants 24-28 completed weeks gestation and birthweight <1200 g will be recruited. The primary outcome will be head growth velocity in the first 28 days of life. Secondary outcomes will include a) auxological data between birth and 36 weeks corrected gestational age b) actual macronutrient intake in first 28 days c) biomarkers of biochemical and metabolic tolerance d) infection biomarkers and other intravascular line complications e) incidence of major complications of prematurity including mortality f) neurodevelopmental outcome at 2 years corrected gestational age</p> <p>Trial registration</p> <p>Current controlled trials: <a href="http://www.controlled-trials.com/ISRCTN76597892">ISRCTN76597892</a>; EudraCT Number: 2008-008899-14</p

Geometry of River Networks II: Distributions of Component Size and Number

The structure of a river network may be seen as a discrete set of nested sub-networks built out of individual stream segments. These network components are assigned an integral stream order via a hierarchical and discrete ordering method. Exponential relationships, known as Horton's laws, between stream order and ensemble-averaged quantities pertaining to network components are observed. We extend these observations to incorporate fluctuations and all higher moments by developing functional relationships between distributions. The relationships determined are drawn from a combination of theoretical analysis, analysis of real river networks including the Mississippi, Amazon and Nile, and numerical simulations on a model of directed, random networks. Underlying distributions of stream segment lengths are identified as exponential. Combinations of these distributions form single-humped distributions with exponential tails, the sums of which are in turn shown to give power law distributions of stream lengths. Distributions of basin area and stream segment frequency are also addressed. The calculations identify a single length-scale as a measure of size fluctuations in network components. This article is the second in a series of three addressing the geometry of river networks.Comment: 16 pages, 13 figures, 4 tables, Revtex4, submitted to PR

V496 Scuti: An Fe II nova with dust shell accompanied by CO emission

We present near-infrared and optical observations of the nova V496 Scuti 2009 covering various phases - pre-maximum, early decline and nebular - during the first 10 months of its discovery followed by limited observations in early part of 2011 April. The spectra follow the evolution of the nova when the lines had strong P Cygni profiles to a phase dominated by prominent emission lines. The notable feature of the near-IR spectra in the early decline phase is the rare presence of first overtone bands of carbon monoxide in emission. Later about 150 days after the peak brightness the IR spectra show clear dust formation in the expanding ejecta. Dust formation in V496 Sct is consistent with the presence of lines of elements with low ionization potentials like Na and Mg in the early spectra and the detection of CO bands in emission. The light curve shows a slow rise to the maximum and a slow decline indicating a prolonged mass loss. This is corroborated by the strengthening of P Cygni profiles during the first 30 days. In the spectra taken close to the optical maximum brightness, the broad and single absorption component seen at the time of discovery is replaced by two sharper components. During the early decline phase two sharp dips that show increasing outflow velocities are seen in the P Cygni absorption components of Fe II and H I lines. The spectra in 2010 March showed the onset of the nebular phase. Several emission lines display saddle-like profiles during the nebular phase. In the nebular stage the observed fluxes of [O III] and H-beta lines are used to estimate the electron number densities and the mass of the ejecta. The optical spectra show that the nova evolved in the P_fe A_o spectral sequence. The physical conditions in the ejecta are estimated. The absolute magnitude and the distance to the nova are estimated to be M_V = -7.0 +/- 0.2 and d = 2.9 +/- 0.3 kpc respectively.Comment: 14 pages, 9 figures and 6 Tables, Accepted for Publication in MNRA

Scaling Relations and Overabundance of Massive Clusters at z>~1 from Weak-Lensing Studies with HST

We present weak gravitational lensing analysis of 22 high-redshift (z >~1) clusters based on Hubble Space Telescope images. Most clusters in our sample provide significant lensing signals and are well detected in their reconstructed two-dimensional mass maps. Combining the current results and our previous weak-lensing studies of five other high-z clusters, we compare gravitational lensing masses of these clusters with other observables. We revisit the question whether the presence of the most massive clusters in our sample is in tension with the current LambdaCDM structure formation paradigm. We find that the lensing masses are tightly correlated with the gas temperatures and establish, for the first time, the lensing mass-temperature relation at z >~ 1. For the power law slope of the M-TX relation (M propto T^{\alpha}), we obtain \alpha=1.54 +/- 0.23. This is consistent with the theoretical self-similar prediction \alpha=3/2 and with the results previously reported in the literature for much lower redshift samples. However, our normalization is lower than the previous results by 20-30%, indicating that the normalization in the M-TX relation might evolve. After correcting for Eddington bias and updating the discovery area with a more conservative choice, we find that the existence of the most massive clusters in our sample still provides a tension with the current Lambda CDM model. The combined probability of finding the four most massive clusters in this sample after marginalization over current cosmological parameters is less than 1%.Comment: ApJ in press. See http://www.supernova.lbl.gov for additional information pertaining to the HST Cluster SN Surve