402 research outputs found
Density matrix for the kink ground state of the ferromagnetic XXZ chain
The exact expression for the density matrix of the kink ground state of the
ferromagnetic XXZ chain is obtained. Utilizing this, we exactly calculate
various correlation functions such as the longitudinal and transverse spin-spin
correlation functions, and the ferromagnetic and antiferromagnetic string
formation probabilities. The asymptotic behaviors of these correlation
functions are also analyzed. As a consequence, we find that the spin-spin
correlation functions decay exponentially for large distances, while the string
formation probabilities exhibit Gaussian decay for large strings. We also
evaluate the entanglement entropy, which shows interesting behaviors due to the
lack of the translational invariance of the state.Comment: 7 pages, 9 figure
Reflection equation for the N=3 Cremmer-Gervais R-matrix
We consider the reflection equation of the N=3 Cremmer-Gervais R-matrix. The
reflection equation is shown to be equivalent to 38 equations which do not
depend on the parameter of the R-matrix, q. Solving those 38 equations. the
solution space is found to be the union of two types of spaces, each of which
is parametrized by the algebraic variety and .Comment: 28 pages, revised versio
On the problem of calculation of correlation functions in the six-vertex model with domain wall boundary conditions
The problem of calculation of correlation functions in the six-vertex model
with domain wall boundary conditions is addressed by considering a particular
nonlocal correlation function, called row configuration probability. This
correlation function can be used as building block for computing various (both
local and nonlocal) correlation functions in the model. The row configuration
probability is calculated using the quantum inverse scattering method; the
final result is given in terms of a multiple integral. The connection with the
emptiness formation probability, another nonlocal correlation function which
was computed elsewhere using similar methods, is also discussed.Comment: 15 pages, 2 figure
An application of incomplete pairwise comparison matrices for ranking top tennis players
Pairwise comparison is an important tool in multi-attribute decision making.
Pairwise comparison matrices (PCM) have been applied for ranking criteria and
for scoring alternatives according to a given criterion. Our paper presents a
special application of incomplete PCMs: ranking of professional tennis players
based on their results against each other. The selected 25 players have been on
the top of the ATP rankings for a shorter or longer period in the last 40
years. Some of them have never met on the court. One of the aims of the paper
is to provide ranking of the selected players, however, the analysis of
incomplete pairwise comparison matrices is also in the focus. The eigenvector
method and the logarithmic least squares method were used to calculate weights
from incomplete PCMs. In our results the top three players of four decades were
Nadal, Federer and Sampras. Some questions have been raised on the properties
of incomplete PCMs and remains open for further investigation.Comment: 14 pages, 2 figure
Factors predisposing 6 to 11-year old children in the first stage of orthodontic treatment to temporomandibular disorders
INTRODUCTION: The etiology of temporomandibular disorders (TMD's) is currently considered multifactorial, involving psychological factors, oral parafunctions, morphological and functional malocclusion. OBJECTIVES: In keeping with this reasoning, we evaluated children who seek preventive orthodontic treatment, to better understand their grievances and to assess the prevalence of TMD signs and symptoms in these patients. METHODS: Two examiners evaluated 65 children aged 6 to 11 years. RESULTS: In our sample, bruxism featured the highest prevalence rate, whereas atypical swallowing displayed the highest rate among predisposing factors. CONCLUSION: We therefore recommend that the evaluation of possible TMD signs and symptoms in children be adopted as routine in the initial clinical examination.INTRODUÇÃO: atualmente, considera-se multifatorial a etiologia da desordem temporomandibular (DTM), na qual fatores psicológicos, parafunções orais, má oclusão morfológica e funcional constituem possíveis causas para o desenvolvimento dessa disfunção. OBJETIVO: avaliar as crianças que procuram por tratamento ortodôntico preventivo, visando compreender melhor suas queixas e avaliar a prevalência de sinais e sintomas de desordem temporomandibular. MÉTODOS: sessenta e cinco crianças, com idades variando entre 6 e 11 anos, foram avaliadas por dois examinadores. RESULTADOS: o bruxismo foi o sintoma que apresentou o maior índice de prevalência na amostra estudada e a deglutição atípica apresentou o maior índice dentre os fatores predisponentes. CONCLUSÃO: recomenda-se que a avaliação dos possíveis sinais e sintomas da DTM em crianças seja adotada como rotina durante o exame clínico inicial.UMESPEPM UNIFESPUNIFESP-EPM Departamento de FonoaudiologiaUniversidade Metodista de São Paulo Faculdade de OdontologiaUNIFESP, EPM, UNIFESP, EPM Depto. de FonoaudiologiaSciEL
Simultaneous disruption of two DNA polymerases, Polη and Polζ, in Avian DT40 cells unmasks the role of Polη in cellular response to various DNA lesions
Replicative DNA polymerases are frequently stalled by DNA lesions. The resulting replication blockage is released by homologous recombination (HR) and translesion DNA synthesis (TLS). TLS employs specialized TLS polymerases to bypass DNA lesions. We provide striking in vivo evidence of the cooperation between DNA polymerase η, which is mutated in the variant form of the cancer predisposition disorder xeroderma pigmentosum (XP-V), and DNA polymerase ζ by generating POLη−/−/POLζ−/− cells from the chicken DT40 cell line. POLζ−/− cells are hypersensitive to a very wide range of DNA damaging agents, whereas XP-V cells exhibit moderate sensitivity to ultraviolet light (UV) only in the presence of caffeine treatment and exhibit no significant sensitivity to any other damaging agents. It is therefore widely believed that Polη plays a very specific role in cellular tolerance to UV-induced DNA damage. The evidence we present challenges this assumption. The phenotypic analysis of POLη−/−/POLζ−/− cells shows that, unexpectedly, the loss of Polη significantly rescued all mutant phenotypes of POLζ−/− cells and results in the restoration of the DNA damage tolerance by a backup pathway including HR. Taken together, Polη contributes to a much wide range of TLS events than had been predicted by the phenotype of XP-V cells
Multiply-refined enumeration of alternating sign matrices
Four natural boundary statistics and two natural bulk statistics are
considered for alternating sign matrices (ASMs). Specifically, these statistics
are the positions of the 1's in the first and last rows and columns of an ASM,
and the numbers of generalized inversions and -1's in an ASM. Previously-known
and related results for the exact enumeration of ASMs with prescribed values of
some of these statistics are discussed in detail. A quadratic relation which
recursively determines the generating function associated with all six
statistics is then obtained. This relation also leads to various new identities
satisfied by generating functions associated with fewer than six of the
statistics. The derivation of the relation involves combining the
Desnanot-Jacobi determinant identity with the Izergin-Korepin formula for the
partition function of the six-vertex model with domain-wall boundary
conditions.Comment: 62 pages; v3 slightly updated relative to published versio
TPXL-1 activates Aurora A to clear contractile ring components from the polar cortex during cytokinesis
During cytokinesis, a signal from the central spindle that forms between the separating anaphase chromosomes promotes the accumulation of contractile ring components at the cell equator, while a signal from the centrosomal microtubule asters inhibits accumulation of contractile ring components at the cell poles. However, the molecular identity of the inhibitory signal has remained unknown. To identify molecular components of the aster-based inhibitory signal, we developed a means to monitor the removal of contractile ring proteins from the polar cortex after anaphase onset. Using this assay, we show that polar clearing is an active process that requires activation of Aurora A kinase by TPXL-1. TPXL-1 concentrates on astral microtubules coincident with polar clearing in anaphase, and its ability to recruit Aurora A and activate its kinase activity are essential for clearing. In summary, our data identify Aurora A kinase as an aster-based inhibitory signal that restricts contractile ring components to the cell equator during cytokinesis.We thank the Caenorhabditis Genetic Center (funded by the National Institutes of Health Office of Research Infrastructure Programs P40 OD010440) for strains. This work was supported by grants to K. Oegema (National Institutes of Health; GM074207), E. Zanin (Deutsche Forschungsgemeinschaft, ZA619/3-1), and A.X. Carvalho (European Research Council; 640553–ACTOMYO). T. Kim was supported by a grant to Arshad Desai (National Institutes of Health; GM074215). K. Oegema receives salary and other support from the Ludwig Institute for Cancer Research. S. Mangal is a member of International Max Planck Research School for Molecular Life Sciences, and J. Sacher is a member of the Life Science Munich graduate program; both thank their programs for support
Third Report on Chicken Genes and Chromosomes 2015
Following on from the First Report on Chicken Genes and Chromosomes [Schmid et al., 2000] and the Second Report in 2005 [Schmid et al., 2005], we are pleased to publish this long-awaited Third Report on the latest developments in chicken genomics. The First Report highlighted the availability of genetic and physical maps, while the Second Report was published as the chicken genome sequence was released. This report comes at a time of huge technological advances (particularly in sequencing methodologies) which have allowed us to examine the chicken genome in detail not possible until now. This has also heralded an explosion in avian genomics, with the current availability of more than 48 bird genomes [Zhang G et al., 2014b; Eöry et al., 2015], with many more planned
Coupling changes in cell shape to chromosome segregation
Animal cells undergo dramatic changes in shape, mechanics and polarity as they progress through the different stages of cell division. These changes begin at mitotic entry, with cell–substrate adhesion remodelling, assembly of a cortical actomyosin network and osmotic swelling, which together enable cells to adopt a near spherical form even when growing in a crowded tissue environment. These shape changes, which probably aid spindle assembly and positioning, are then reversed at mitotic exit to restore the interphase cell morphology. Here, we discuss the dynamics, regulation and function of these processes, and how cell shape changes and sister chromatid segregation are coupled to ensure that the daughter cells generated through division receive their fair inheritance
- …
