Una mirada jurídica al caso Arias y a la doble conformidad. Comentarios a la Sentencia SU-146 de 2020 de la Corte Constitucional

The Sentence SU­146 of 2020, by which the court decided to order the Criminal Cassation Chamber of the Supreme Court of Justice to initiate “the process to resolve the request to challenge the sentence in sole instance issued against citizen Andrés Felipe Arias Leiva” is a current political discussion. This is why it is taken as the object of analysis to make respective comments, in addition, to relate to this the principle of conformity and its evolution in the order.La Sentencia SU­146 de 2020 por la cual el tribunal decidió ordenar a la Sala de Casación Penal de la Corte Suprema de Justicia que iniciara “el trámite para resolver la solicitud de impugnación de la condena en única instancia proferida en contra del ciudadano Andrés Felipe Arias Leiva” es una actual discusión política. Es por esto que se toma como objeto de análisis para realizar comentarios respectivos, además, de relacionar a este el principio de conformidad y su evolución en el ordenamiento

Una mirada jurídica al caso Arias y a la doble conformidad. Comentarios a la Sentencia SU-146 de 2020 de la Corte Constitucional

The Sentence SU­146 of 2020, by which the court decided to order the Criminal Cassation Chamber of the Supreme Court of Justice to initiate “the process to resolve the request to challenge the sentence in sole instance issued against citizen Andrés Felipe Arias Leiva” is a current political discussion. This is why it is taken as the object of analysis to make respective comments, in addition, to relate to this the principle of conformity and its evolution in the order.La Sentencia SU­146 de 2020 por la cual el tribunal decidió ordenar a la Sala de Casación Penal de la Corte Suprema de Justicia que iniciara “el trámite para resolver la solicitud de impugnación de la condena en única instancia proferida en contra del ciudadano Andrés Felipe Arias Leiva” es una actual discusión política. Es por esto que se toma como objeto de análisis para realizar comentarios respectivos, además, de relacionar a este el principio de conformidad y su evolución en el ordenamiento

Effects of dietary chromium-yeast level on growth performance, blood metabolites, meat traits and muscle fatty acids profile, and microminerals content in liver and bone of lambs

To assess the effect of dietary supplement levels of chromium-yeast (Cr-yeast) on growth performance, blood glucose and triglycerides, fatty acid (FA) profile in intramuscular fat, carcase and meat traits, iron, copper, chromium and zinc concentrations in liver and bone, 24 Rambouillet male lambs (29.2 ± 0.17 kg body weight) were randomly assigned to four diets with 0, 0.2, 0.4 and 0.6mg Cr/kg DM. The growth performance trial lasted 49 d. Supplemental Cryeast did not affect growth performance and carcase characteristics (p>.05), but reduced (p<.05) perirenal and intramuscular fat, as well as 3 h post-feeding blood glucose and triglycerides concentration. In liver, Fe and Cu concentration decreased (p<.05), while Cr concentrations in liver increased with increasing Cr-yeast dietary levels. In bone, Fe decreased (p<.05) as Cryeast dietary levels increasing, and Cr-yeast supplementation increased Cr concentrations (p<.05). As Cr-yeast dietary level increased, palmitic (C16:0) and stearic (C18:0) SFA decreased linearly (p<.05), while palmitoleic (C16:1n-7), vaccenic (C18:1n-7), linoleic (C18:2n-6) and arachidic (C20:4) unsaturated fatty acids (UFA) increased linearly (p<.01). In conclusion, Cr-yeast did not affect growth performance and carcase quality, but decreased the perirenal and intramuscular fat, blood glucose and triglyceride content, and Fe and Cu concentrations in liver as increased Cr-yeast levels in the diet. Because supplemental Cr-yeast improved index of atherogenicity and unsaturated to saturated FA ratio in muscle of lambs, it could be of human nutritional interest

Ingeniería de software en crecimiento: enfoque conceptual y metodológico, y herramientas

Las temáticas abordas por la Ingeniería de Software (IS) abarca problemas que van desde la gestión del proyecto de desarrollo de software, hasta el mantenimiento del producto resultante. Los desafíos de la IS se encuentran en los entornos de ejecución heterogéneos y de diferentes plataformas, los tiempos de entrega de los sistemas, y la continua evolución hacia sistemas de computación extremadamente grandes, altamente dinámicos y heterogéneos que desafían los fundamentos, modelos y herramientas de la ingeniería de software. El objetivo del proyecto es el estudio de los retos de la IS y su ámbito de aplicación. Se plantea como hipótesis de trabajo la necesidad de retroalimentación entre la actividad de investigación y el ámbito real de aplicación de desarrollo de software, empresas y organizaciones gubernamentales. Desde esta perspectiva, el marco de trabajo propuesto se centra en las experiencias que, de ser pertinentes, propongan modificaciones a las prácticas y, por efecto sinérgico, a los conceptos que la sustentan. Esto resultará en la revisión de técnicas, metodologías, y el desarrollo de herramientas que asistan al desarrollo de sistemas de software.Eje: Ingeniería de SoftwareRed de Universidades con Carreras en Informática (RedUNCI

Inflammasomes NLRP3 and AIM2 in peri-implantitis: A cross-sectional study

Background: Inflammasome components NLRP3 and AIM2 contribute to inflammation development by the activation of caspase-1 and IL-1β. They have not been yet evaluated in samples from patients with active peri-implantitis. Thus, the aim of the present study is to analyze the expression of inflammasomes NLRP3 and AIM2 and subsequent caspase 1 and IL-1β assessing the microenvironment of leukocyte subsets in samples from patients with active peri-implantitis. Methods: Biopsies were collected from 33 implants in 21 patients being treated for peri-implantitis. Biopsies from gingival tissues from 15 patients with healthy periodontium were also collected for control. These tissues were evaluated through conventional histological stainings. Then, immunohistochemical detection was performed to analyze NLRP3, AIM2, caspase-1, and IL-1β and markers of different leukocyte subsets. PCR for inflammasomes and related genes was also done. Results: This manuscript reveals a high immunohistochemical and mRNA expression of NLRP3 and AIM2 inflammasomes, caspase-1, and IL-1β in biopsies collected from human peri-implantitis. The expression of the tested markers was significantly correlated with the increase in inflammatory infiltrate, probing depth, presence of biofilm, and bleeding on probing. In these peri-implantitis lesions, the area of biopsy tissue occupied by inflammatory infiltrate was intense while the area occupied by collagen was significantly lower. In comparison with periodontal healthy tissues, the inflammatory infiltrate was statistically significantly higher in the peri-implantitis biopsies and was mainly composed of plasma cells, followed by T and B lymphocytes. Conclusion: In human peri-implantitis, chronic inflammation can be explained in part by the action of IL-1β/ caspase 1 induced through NLRP3 and AIM2 inflammasome activation.Junta de Andalucía, Grant/Award Number: CTS-138CTS-1028; Universidad de Granada, Grant/Award Number: B-CTS- 504- UGR18Universidad de Granada/CBU

Improving Arctic weather and seasonal climate prediction: recommendations for future forecast systems evolution from the European project APPLICATE

The Arctic environment is changing, increasing the vulnerability of local communities and ecosystems, and impacting its socio-economic landscape. In this context, weather and climate prediction systems can be powerful tools to support strategic planning and decision-making at different time horizons. This article presents several success stories from the H2020 project APPLICATE on how to advance Arctic weather and seasonal climate prediction, synthesizing the key lessons learned throughout the project and providing recommendations for future model and forecast system development.The results discussed in this article were supported by the project APPLICATE (727862), funded by the European Union's Horizon 2020 research and innovation programme. PO was additionally supported by the Spanish fellowship RYC-2017-22772.Peer ReviewedArticle signat per 29 autors/es: Pablo Ortega (1), Edward W. Blockley (2), Morten Køltzow (3), François Massonnet (4), Irina Sandu (5), Gunilla Svensson (6), Juan C. Acosta Navarro (1), Gabriele Arduini (5), Lauriane Batté (7), Eric Bazile (7), Matthieu Chevallier (8), Rubén Cruz-García (1), Jonathan J. Day (5), Thierry Fichefet (4), Daniela Flocco (9), Mukesh Gupta (4), Kerstin Hartung (6,10), Ed Hawkins (9), Claudia Hinrichs (11), Linus Magnusson (5), Eduardo Moreno-Chamarro (1), Sergio Pérez-Montero (1), Leandro Ponsoni (4), Tido Semmler (11), Doug Smith (2), Jean Sterlin (4), Michael Tjernström (6), Ilona Välisuo (7,12), and Thomas Jung (11,13) // (1) Barcelona Supercomputing Center, Barcelona, Spain | (2) Met Office, Exeter, UK | (3) Norwegian Meteorological Institute, Oslo, Norway | (4) Université catholique de Louvain, Earth and Life Institute, Georges Lemaître Centre for Earth and Climate Research, Louvain-la-Neuve, Belgium | (5) European Centre for Medium-Range Weather Forecasts, Reading, UK | (6) Department of Meteorology, Stockholm University, Stockholm, Sweden | (7) CNRM, Université de Toulouse, Météo-France, CNRS, Toulouse, France | (8) Météo-France, Toulouse, France | (9) National Centre for Atmospheric Science, Department of Meteorology, University of Reading, Reading, UK. | (10) Now at: Deutsches Zentrum für Luft- und Raumfahrt, Institut für Physik der Atmosphäre, Oberpfaffenhofen, Germany | (11) Alfred Wegener Institute, Helmholtz Centre for Polar and Marine Research, Bremerhaven, Germany | (12) Now at: Meteorology Unit, Finnish Meteorological Institute, Helsinki, Finland | (13) Department of Physics and Electrical Engineering, University of Bremen, Bremen, GermanyPostprint (published version

Biological diversity and food security offered by the urban gardens of the Andean – Amazonian highlands in the Sibundoy Valley, Putumayo, Colombia

La presente investigación tiene un diseño metodológico descriptivo y transversal, no experimental, enfocado al estudio de las plantas cultivadas en las huertas y el manejo por sus propietarios con el fin de asegurar la seguridad alimentaria y la diversidad biológica. Se evaluaron diez huertas urbanas familiares ubicadas en el municipio de Sibundoy, Putumayo, Colombia, en las cuales se estudió un total de 31.776 individuos pertenecientes a 113 especies de 45 familias botánicas. Según los propietarios de las huertas, se consideraron importantes 91 especies de plantas comestibles que fueron incluidas en la categoría de uso comestible, siendo la alimentación la principal finalidad de estas huertas familiares, destacando en segundo plano las plantas de uso medicinal. Se evaluó la diversidad biológica con los índices de Margalef, Shannon, Simpson, el análisis de similitud de Jaccard y el método de rarefacción con la ayuda del software libre DIVA-GIS 7,5 © para analizar la riqueza y distribución de especies, encontrando un alto índice de biodiversidad en las huertas estudiadas.The present investigation had a descriptive and transversal methodological design, not experimental, focused on the study of plants grown in the gardens and the management by their owners in order to guarantee food security and biological diversity. Ten family urban gardens located in the municipality of Sibundoy, Putumayo, Colombia were evaluated, 31,776 individuals belonging to 113 species from 45 botanical families were studied. According to the owners of the orchards, 91 species of edible plants that were included in the category of edible use were considered important, with food being the main purpose of these family gardens, highlighting in the background the medicinal plants. The biological diversity was evaluated with the indices of Margalef, Shannon, Simpson, the Jaccard similarity analysis and the rarefaction method with the help of the free software DIVA-GIS 7.5 © to analyze the richness and distribution of species, finding a high biodiversity index in the orchards studied

The EC-Earth3 Earth system model for the Coupled Model Intercomparison Project 6

The Earth system model EC-Earth3 for contributions to CMIP6 is documented here, with its flexible coupling framework, major model configurations, a methodology for ensuring the simulations are comparable across different high-performance computing (HPC) systems, and with the physical performance of base configurations over the historical period. The variety of possible configurations and sub-models reflects the broad interests in the EC-Earth community. EC-Earth3 key performance metrics demonstrate physical behavior and biases well within the frame known from recent CMIP models. With improved physical and dynamic features, new Earth system model (ESM) components, community tools, and largely improved physical performance compared to the CMIP5 version, EC-Earth3 represents a clear step forward for the only European community ESM. We demonstrate here that EC-Earth3 is suited for a range of tasks in CMIP6 and beyond.The development of EC-Earth3 was supported by the European Union's Horizon 2020 research and innovation program under project IS-ENES3, the third phase of the distributed e-infrastructure of the European Network for Earth System Modelling (ENES) (grant agreement no. 824084, PRIMAVERA grant no. 641727, and CRESCENDO grant no. 641816). Etienne Tourigny and Raffaele Bernardello have received funding from the European Union’s Horizon 2020 research and innovation program under Marie Skłodowska-Curie grant agreement nos. 748750 (SPFireSD project) and 708063 (NeTNPPAO project). Ivana Cvijanovic was supported by Generalitat de Catalunya (Secretaria d'Universitats i Recerca del Departament d’Empresa i Coneixement) through the Beatriu de Pinós program. Yohan Ruprich-Robert was funded by the European Union's Horizon 2020 research and innovation program in the framework of Marie Skłodowska-Curie grant INADEC (grant agreement 800154). Paul A. Miller, Lars Nieradzik, David Wårlind, Roland Schrödner, and Benjamin Smith acknowledge financial support from the strategic research area “Modeling the Regional and Global Earth System” (MERGE) and the Lund University Centre for Studies of Carbon Cycle and Climate Interactions (LUCCI). Paul A. Miller, David Wårlind, and Benjamin Smith acknowledge financial support from the Swedish national strategic e-science research program eSSENCE. Paul A. Miller further acknowledges financial support from the Swedish Research Council (Vetenskapsrådet) under project no. 621-2013-5487. Shuting Yang acknowledges financial support from a Synergy Grant from the European Research Council under the European Community's Seventh Framework Programme (FP7/2007-2013)/ERC (grant agreement 610055) as part of the ice2ice project and the NordForsk-funded Nordic Centre of Excellence project (award 76654) ARCPATH. Marianne Sloth Madsen acknowledges financial support from the Danish National Center for Climate Research (NCKF). Andrea Alessandri and Peter Anthoni acknowledge funding from the Helmholtz Association in its ATMO program. Thomas Arsouze, Arthur Ramos, and Valentina Sicardi received funding from the Ministerio de Ciencia, Innovación y Universidades as part of the DeCUSO project (CGL2017-84493-R).​​​​​​​Peer Reviewed"Article signat per 61 autors/es: Ralf Döscher, Mario Acosta, Andrea Alessandri, Peter Anthoni, Thomas Arsouze, Tommi Bergman, Raffaele Bernardello, Souhail Boussetta, Louis-Philippe Caron, Glenn Carver, Miguel Castrillo, Franco Catalano, Ivana Cvijanovic, Paolo Davini, Evelien Dekker, Francisco J. Doblas-Reyes, David Docquier, Pablo Echevarria, Uwe Fladrich, Ramon Fuentes-Franco, Matthias Gröger, Jost v. Hardenberg, Jenny Hieronymus, M. Pasha Karami, Jukka-Pekka Keskinen, Torben Koenigk, Risto Makkonen, François Massonnet, Martin Ménégoz, Paul A. Miller, Eduardo Moreno-Chamarro, Lars Nieradzik, Twan van Noije, Paul Nolan, Declan O'Donnell, Pirkka Ollinaho11, Gijs van den Oord, Pablo Ortega, Oriol Tintó Prims, Arthur Ramos, Thomas Reerink, Clement Rousset, Yohan Ruprich-Robert, Philippe Le Sager, Torben Schmith, Roland Schrödner, Federico Serva, Valentina Sicardi, Marianne Sloth Madsen, Benjamin Smith, Tian Tian, Etienne Tourigny, Petteri Uotila, Martin Vancoppenolle, Shiyu Wang, David Wårlind, Ulrika Willén, Klaus Wyser, Shuting Yang, Xavier Yepes-Arbós, and Qiong Zhang"Postprint (author's final draft

Diversity for chemical composition in a collection of different varietal types of tree tomato (Solanum betaceum Cav.), an Andean exotic fruit

[EN] We evaluated 23 tree tomato (Solanum betaceum) accessions from five cultivar groups and one wild relative (Solanum cajanumense) for 26 composition traits. For all traits we found highly significant differences (P < 0.001) among the materials studied. The high diversity found within S. betaceum for composition traits was matched by a high diversity within each of the cultivar groups. We found that sucrose and citric acid were the most important soluble sugar and organic acid, respectively, in tree tomato. Fruit in the anthocyanin pigmented (purple) group had a carotenoid content similar to that in the yellow-orange cultivar groups. Total phenolic content was significantly correlated (r = 0.8607) with antioxidant activity. Analyses of mineral content showed that tree tomato is a good source of K, Mg, and Cu. Multivariate principal components analysis (PCA) confirmed that an important diversity exists within each cultivar group. The results we have obtained indicate that the high diversity found within the tree tomato could be exploited for selection and breeding for developing the tree tomato as a commercial crop. (C) 2014 Elsevier Ltd. All rights reserved.This work was partially financed by the Ecuadorian Secretaria Nacional de Educacion Superior, Ciencia, Tecnologia e Innovacion from Ecuador (SENESCYT).Acosta-Quezada, P.; Raigón Jiménez, MD.; Riofrío-Cuenca, T.; García Martínez, MD.; Plazas Ávila, MDLO.; Burneo, J.; Figueroa, JG.... (2015). Diversity for chemical composition in a collection of different varietal types of tree tomato (Solanum betaceum Cav.), an Andean exotic fruit. Food Chemistry. 169:327-335. doi:10.1016/j.foodchem.2014.07.152S32733516