Detection and Characterization of Prevotella Intermedia and Its In Vitro Susceptibility to Selected Antimicrobial Agents in Chronic Periodontitis and Acute Myocardial Infarction

Background: Periodontal disease has been reported to play a causative role in acute myocardial infarction (AMI), which may add to the various risk factors associated with coronary heart disease. The objective of the present study was to investigate the presence of Prevotella intermedia – an established periodontal pathogen – in subgingival plaque samples of chronic periodontitis and AMI patients in order to identify a possible association, and to evaluate the susceptibility of Prevotella intermedia to nine antimicrobial agents. Methods: After undergoing screening for eligibility, a total of 50 subjects were included in the present study. Twenty patients were diagnosed with AMI and generalized chronic periodontitis (Group I), 20 patients were diagnosed with only AMI (Group II), and 10 subjects were healthy controls (Group III). The isolated Prevotella intermedia strains were tested for susceptibility to bacitracin, chloramphenicol, penicillin G, polymyxin, gentamycin, neomycin, tetracycline, cefotaxime, and cefoxitin using an antibiotic zonescale to determine minimum inhibitory concentrations (MICs). Results: Periodontal pathogens were identified by phenotypic and enzymatic methods. The mean bacterial load of Prevotella intermedia species was higher in Group I compared to Group II and Group III. It was also found that pencillin G, gentamycin, neomycin, tetracycline, cefotaxime, and cefoxitin inhibited 90% of Prevotella intermedia, whereas bacitracin, chloramphenicol, and polymyxin inhibited 80% of Prevotella intermedia. Thus, only 10% of Prevotella intermedia were resistant to these antibiotics. Conclusion: The present study confirms that Prevotella intermedia is associated with chronic periodontitis and AMI

Meeting IMT 2030 Performance Targets: The Potential of OTFDM Waveform and Structural MIMO Technologies

The white paper focuses on several candidate technologies that could play a crucial role in the development of 6G systems. Two of the key technologies explored in detail are Orthogonal Time Frequency Division Multiplexing (OTFDM) waveform and Structural MIMO (S-MIMO)

Nuclear Fractal Dimension in Diagnosing Oral Cancer- A Systematic Review

Background: Fractal analysis, which derives from fractal geometry, is used to put a number on the degree of shape complexity. Recent research have looked at the use of fractal analysis for tumour characterization. Objective: The systematic review's goal is to determine whether using the fractal dimension as a diagnostic tool can help detect oral squamous cell cancer in its earliest stages. Methodology: By adhering to three main criteria, all research articles published between the years of 2008 and 2020 in three major scientific databases, including PubMed, Scopus, and Web of Science, were included. The selection criteria for the investigation were based on fractal dimension analysis in diagnosing oral cancer, nuclear fractal dimension analysis in identifying the nuclear structure before and after treatment of oral carcinomas. Results: Use of nuclear fractal analysis by dental professionals will help in diagnosing oral cancer at an early stage itself which further has its effect on treatment outcome. All the ten included studies have shown that fractal geometry is a useful objective tool in diagnosing oral cancer.  The risk was assessed done by Cochrane risk assessment model based on the several domains used was roughly 53% low risk, 30% ambiguous, and 15% high risk of bias. Conclusion: All three of the objectives of this systematic study that were used as benchmarks improved as a result of the fractal dimension technique. Early detection of the healthy and sick architecture of the nucleus in cases of oral cancer was made possible by the use of fractal dimension principles. It also helps in assessing and comparing nuclear characteristics of cancer cases before and after treatment. Significance: Applying the principles of nuclear fractal dimension improves the diagnosis of oral carcinomas at early stages

A BIBLIOMETRIC ANALYSIS OF THE 100 MOST CITED ARTICLES IN TOP RANKED DENTAL JOURNAL

Aim: To review the notable characteristics of the 100 most cited articles in dental journals with the highest impact factor according to journal citation reports 2021 by Clarivate analytics. Methods: From the Web of Science database, the impact factor of dental journals was collected. Then, the top 100 cited articles from the top-ranked dental journal were retrieved from the Web of Science database up to June 2021 and cross-matched with Scopus and Google scholar. The following data were gathered for each article including the number of citations, title, year of publication, authors, country and institute, study design, the strength of supporting evidence, and area of research. Results: Journal of Clinical Periodontology (JCP) had the greatest impact factor of 8.728 in the Dentistry, Oral Surgery, and Medicine category. The 100 most cited articles in JCP were published between 1974 and 2018, with the numbers of citations ranging from 2652 to 257 (Web of Science), 2754 to 207 (Scopus), and 4965 to 344 (Google scholar). Lindhe J tops the list with 29 articles followed by Socransky SS with 15. Gothenburg University, Sweden took the leading position with 27 articles followed by Forsyth Dental Centre, United States with 12. The list was represented mainly by articles with experimental study designs and level-I evidence. Surgical periodontal therapy was the most studied thematic area. Conclusions: Our findings reveal trends and preferences in the research component of a top-ranked journal in dentistry. There is considerable evidence of exceedingly citable articles with superior research design and a high level of evidence being published

Evaluation of Comfort Levels of Patient and Ergonomics of the Dental Surgeon during Manual Scaling under Both Proprioceptive Derivative Concept and Conventional Approach: A Cross-sectional Study

Introduction: The important components that contribute to successful dental care are maximum accessibility, visibility, comfort, and control over clinical processes. Dental practitioners are more prone to developing musculoskeletal disorders due to awkward working postures. To minimise all these risk factors, a new concept called Proprioceptive Derivative (PD) has come into existence. Aim: The main aim of this study was to evaluate the comfort levels of the patient and ergonomics of the dental professional in the PD approach and conventional approach. Materials and Methods: A cross-sectional study was conducted in which manual scaling was performed by 20 dentists on 120 patients using the PD concept and conventional concept. A 13-item questionnaire was distributed among the patients and clinicians to record their perceptions of comfort levels, clinicians’ treatment satisfaction levels, and the time needed to complete the procedure after mastering the PD concept. In indepedent sample t-test was use to compare the responses among the two groups. p≤0.05 was considered statistically significant. Results: The comfort levels of the clinician (q1) during treatment in the conventional approach, with a mean value of 2.96±0.69, were significantly lower than in the PD approach, with a mean value of 3.46±0.85 (p<0.001). However, from the perspective of the patients, the mean comfort levels using the conventional strategy were 2.61±1.03, while using the PD approach, it was 2.85±1.11, which was not statistically significant (p>0.05). Conclusion: The clinicians had more ergonomic benefits and improved time factors under the PD concept. By following the work postures according to the PD concept, clinicians can avoid musculoskeletal discomfort, which is beneficial to all clinicians and can increase the longevity of their clinical practice