Issue 2: Imagining a Community-Led, Multi-Service Delivery Model for Ontario Child Welfare: A Framework for Collaboration Among African Canadian Community Partners

This article imagines a new model for child welfare in Ontario, specifically for African Canadian children, youth, and families. Throughout the article, we discuss both what needs to be changed and how those changes can be achieved, including the development and implementation of community-led organizational structures, programs, and services, and the restructuring of government-community relations and funding allocation, to enable African Canadian community-based agencies to deliver preventative, culturally relevant, family-centred supportive services to African Canadians. The article outlines the development of a community-led, multi-service delivery model for Ontario child welfare, and the potential challenges and opportunities for the delivery of such services to African Canadian children, youth, and families

New genetic loci link adipose and insulin biology to body fat distribution.

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic outcomes, independent of overall adiposity. To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related to waist and hip circumferences in up to 224,459 individuals. We identify 49 loci (33 new) associated with waist-to-hip ratio adjusted for body mass index (BMI), and an additional 19 loci newly associated with related waist and hip circumference measures (P < 5 × 10(-8)). In total, 20 of the 49 waist-to-hip ratio adjusted for BMI loci show significant sexual dimorphism, 19 of which display a stronger effect in women. The identified loci were enriched for genes expressed in adipose tissue and for putative regulatory elements in adipocytes. Pathway analyses implicated adipogenesis, angiogenesis, transcriptional regulation and insulin resistance as processes affecting fat distribution, providing insight into potential pathophysiological mechanisms

Issue 2: Imagining a Community-Led, Multi-Service Delivery Model for Ontario Child Welfare: A Framework for Collaboration Among African Canadian Community Partners

This article imagines a new model for child welfare in Ontario, specifically for African Canadian children, youth, and families. Throughout the article, we discuss both what needs to be changed and how those changes can be achieved, including the development and implementation of community-led organizational structures, programs, and services, and the restructuring of government-community relations and funding allocation, to enable African Canadian community-based agencies to deliver preventative, culturally relevant, family-centred supportive services to African Canadians. The article outlines the development of a community-led, multi-service delivery model for Ontario child welfare, and the potential challenges and opportunities for the delivery of such services to African Canadian children, youth, and families