Fatalities due to intestinal obstruction following the ingestion of foreign bodies

Two fatalities due to an occlusive ileus following the ingestion of foreign bodies in patients with psychiatric disorders are described. A severely mentally handicapped young man developed a temperature and died 1 h after admission to a surgical ward. At autopsy, not, vert, similar 2000 cm3 of foreign material, including broken glass and porcelain, branches, buttons, parts of clothing and other material were found in the gastrointestinal tract, leading to a complete obstruction of the distal intestine and colon with resulting faecal vomiting. The other case was even more unusual as a hair fetishist had swallowed a thick strand of his own hair, 50 cm long, also resulting in mechanical obstruction of the distal intestine

Experimental loss of menisci, cartilage and subchondral bone gradually increases anteroposterior knee laxity

Purpose: Anteroposterior knee stability is a relevant factor for the decision-making process of various surgical procedures. In degenerative joints when the implantation of unicompartimental prostheses or corrective osteotomies of the limb are planned, the integrity of the anteroposterior stability with an intact ACL has been regarded as a necessary prerequisite. We hypothesise that joint degeneration, however, may influence the anteroposterior knee laxity. Therefore, we set out to test this hypothesis simulating a progressively ‘degenerated' joint in an experimental cadaveric setting. Methods: Twelve intact transfemorally resected Thiel-fixated cadaver knee joints were divided into 2 groups for manipulation in the medial or lateral compartment. In each knee, we performed (1) unilateral total meniscectomy; (2) simulation of advanced osteoarthritis, by unilateral total cartilage debridement; (3) simulation of a unilateral tibial impression fracture, by resection of 5mm of the tibial plateau; (4) transection of the ACL. The KT-1000 arthrometer was used to measure the extent of anteroposterior translation at 30° of knee flexion. Results: The mean value for tibial anteroposterior translation before intervention was 3.2mm (SD: ±0.8). The mean translation after each intervention was 4.6mm (SD: ±0.9; +44%; n.s.) after meniscectomy, 5.9mm (SD: ±1.5; +84%; P<0.05) after cartilage debridement, 8mm (SD: ±1.5; +150%; P<0.01) after bone debridement, and finally 9.7mm (SD: ±2.2; +203%; P<0.05) after resection of the ACL. There were no significant differences between the medial and lateral compartment. Conclusion: In absence of massive osteophytes or capsular shrinkage, rapid loss of meniscus, cartilage and particularly loss of subchondral bone may result in a massive increase in anteroposterior translation, mimicking a tear of the ACL. In such a situation, a false positive impression of a ligamentous injury may arise, and decision making is falsely directed away from totally or partially knee joint-preserving procedures. Therefore, in degenerate joints, clinical evaluation of anteroposterior stability should rather rely on the presence of a firm stop than an overall increased joint translatio

Soziale Ungleichheit und die Rolle sozialer Beziehungen in der (Ganztags-)Schule. Kein Thema für die Fortbildung?

Die soziale Ungleichheit in Deutschland reproduziert sich im Schulsystem noch immer hartnäckig. Das untermauern der jüngste Nationale Bildungsbericht ebenso wie der IQB-Bildungstrend erneut mit aktuellen Daten. Die Corona-Pandemie hat den Zusammenhang von sozialer Herkunft und Bildungserfolg verschärft. Folglich verschlechtern sich die Chancen auf Bildung und Teilhabe von Kindern und Jugendlichen, die in Armut aufwachsen, massiv weiter. Es gibt viel zu tun – auf allen Ebenen: in der Politik und Systemsteuerung, an den Einzelschulen und in der Fortbildung von Lehr- und Fachkräften. Im Projekt ACT-2GETHER haben wir den Fokus bewusst auf das Thema Fortbildung gesetzt, da wir als Partnernetzwerk hier einen Hebel beim Abbau von Benachteiligung sehen. [...] Die Projektpartner von ACT2GETHER wollten wissen, wie Lehr- und Fachkräfte bestmöglich unterstützt werden können: Welche Kompetenzen brauchen sie? Und was benötigen benachteiligte Kinder und Jugendliche im Schulalltag von ihnen? Welche Antworten können Fortbildung bzw. Professionalisierung hier geben? (DIPF/Orig.

The Coptic Wizard's Hoard

This is the publisher's version, also available electronically from http://journals.cambridge.org/action/displayAbstract?fromPage=online&aid=7824067&fileId=S0017816000030224.Within the large collection of ancient manuscripts at the University of Michigan there is a group of Coptic papyri which appears to have been a hoard or library of ancient magical texts. Produced by five copyists sometime in the fourth through seventh centuries and originating from a now unknown location in Egypt, the collection was brought to the British Museum by Sir E. A. Wallis Budge in February 1921 for restoration by C. T. Lamacraft; in August of that year, it underwent philological examination by the Coptic lexicographer Walter E. Crum, and was later forwarded to the University of Michigan

The DEPOSIT computer code: calculations of electron-loss cross sections for complex ions colliding with neutral atoms

A description of the DEPOSIT computer code is presented. The code is intended to calculate total and m-fold electron-loss cross sections (m is the number of ionized electrons) and the energy T(b) deposited to the projectile (positive or negative ion) during a collision with a neutral atom at low and intermediate collision energies as a function of the impact parameter b. The deposited energy is calculated as a 3D-integral over the projectile coordinate space in the classical energy-deposition model. Examples of the calculated deposited energies, ionization probabilities and electron-loss cross sections are given as well as the description of the input and output data.Comment: 11 pages, 3 figure

The Multidimensional Prognostic Index in general practice: One-year follow-up study.

BACKGROUND Older patients' health problems in general practice (GP) can often not be assigned to a specific disease, requiring a paradigm shift to goal-oriented, personalised care for clinical decision making. PURPOSE To investigate the predictive value of the comprehensive geriatric assessment (CGA)-based Multidimensional Prognostic Index (MPI) in a GP setting with respect to the main healthcare indicators during the 12 months following initial evaluation. METHODS One hundred twenty-five consecutive patients aged 70 years and older were enrolled in a GP and followed up to one year. All patients underwent a CGA based on which the MPI was calculated and subdivided into three risk groups (MPI-1, 0-0.33 = low risk, MPI-2, 0.34-0.66 = moderate risk and MPI-3, 0.67-1, severe risk). Grade of Care (GC), hospitalization rate, mortality, nursing home admission, use of home care services, falls, number of general practitioner contacts (GPC), of geriatric resources (GR) and geriatric syndromes (GS) during the 12 months following initial evaluation were collected. RESULTS The MPI was significantly associated with number of GS (P < .001), GR (P < .001), GC (P < .001) as well as with the average number of GPC per year (mean 10.4, P = .046). Interestingly, the clinical judgement of the general practitioner, in this case knowing his patients for 16 years on average, was associated with adverse outcomes to a similar extent than the prediction offered by the MPI (GP/adverse outcomes and MPI/adverse outcomes P < .001). CONCLUSION The MPI is strongly associated with adverse outcomes in older GP patients and strongly predicts the number of GPC up to one year after initial evaluation. Considering the feasibility and the strong clinimetric properties of the MPI, its collection should be encouraged as early as possible to disclose risk conditions, implement tailored preventive strategies and improve cost-effectiveness of healthcare resources use

ESID: A Visual Analytics Tool to Epidemiological Emergencies

Visual analysis tools can help illustrate the spread of infectious diseases and enable informed decisions on epidemiology and public health issues. To create visualisation tools that are intuitive, easy to use, and effective in communicating information, continued research and development focusing on user-centric and methodological design models is extremely important. As a contribution to this topic, this paper presents the design and development of the visual analytics application ESID (Epidemiological Scenarios for Infectious Diseases). The goal of ESID is to provide a platform for rapid assessment of the most effective interventions for infectious disease control. ESID provides spatial-temporal analysis, forecasting, comparison of simulations, interactive filters, and accessibility options. In its current form, it shows the simulations of a hybrid graph-equation-based model as introduced in for infection control. The model can be stratified for different age groups and takes into account the properties of the infectious disease as well as human mobility and contact behaviour.Comment: 6 pages, 5 images and 1 table, Eurovis workshop on visual analytics (EuroVA) 202

Effects of insulin-like growth factor-1 on retinal endothelial cell glucose transport and proliferation

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/65813/1/j.1471-4159.2001.00325.x.pd