TESS Discovery of an ultra-short-period planet around the nearby M dwarf LHS 3844

Data from the newly-commissioned \textit{Transiting Exoplanet Survey Satellite} (TESS) has revealed a "hot Earth" around LHS 3844, an M dwarf located 15 pc away. The planet has a radius of $1.32\pm 0.02$ $R_\oplus$ and orbits the star every 11 hours. Although the existence of an atmosphere around such a strongly irradiated planet is questionable, the star is bright enough ($I=11.9$, $K=9.1$) for this possibility to be investigated with transit and occultation spectroscopy. The star's brightness and the planet's short period will also facilitate the measurement of the planet's mass through Doppler spectroscopy.Comment: 10 pages, 4 figures. Submitted to ApJ Letters. This letter makes use of the TESS Alert data, which is currently in a beta test phase, using data from the pipelines at the TESS Science Office and at the TESS Science Processing Operations Cente

TOI 540 b: A Planet Smaller than Earth Orbiting a Nearby Rapidly Rotating Low-mass Star

We present the discovery of TOI 540 b, a hot planet slightly smaller than Earth orbiting the low-mass star 2MASS J05051443-4756154. The planet has an orbital period of $P = 1.239149$ days ($\pm$ 170 ms) and a radius of $r = 0.903 \pm 0.052 R_{\rm Earth}$, and is likely terrestrial based on the observed mass-radius distribution of small exoplanets at similar insolations. The star is 14.008 pc away and we estimate its mass and radius to be $M = 0.159 \pm 0.014 M_{\rm Sun}$ and $R = 0.1895 \pm 0.0079 R_{\rm Sun}$, respectively. The star is distinctive in its very short rotational period of $P_{\rm rot} = 17.4264 +/- 0.0094$ hours and correspondingly small Rossby number of 0.007 as well as its high X-ray-to-bolometric luminosity ratio of $L_X / L_{\rm bol} = 0.0028$ based on a serendipitous XMM-Newton detection during a slew operation. This is consistent with the X-ray emission being observed at a maximum value of $L_X / L_{\rm bol} \simeq 10^{-3}$ as predicted for the most rapidly rotating M dwarfs. TOI 540 b may be an alluring target to study atmospheric erosion due to the strong stellar X-ray emission. It is also among the most accessible targets for transmission and emission spectroscopy and eclipse photometry with JWST, and may permit Doppler tomography with high-resolution spectroscopy during transit. This discovery is based on precise photometric data from TESS and ground-based follow-up observations by the MEarth team.Comment: 18 pages, 7 figures. Accepted for publication in The Astronomical Journa

A review of the current treatment methods for posthaemorrhagic hydrocephalus of infants

Posthaemorrhagic hydrocephalus (PHH) is a major problem for premature infants, generally requiring lifelong care. It results from small blood clots inducing scarring within CSF channels impeding CSF circulation. Transforming growth factor – beta is released into CSF and cytokines stimulate deposition of extracellular matrix proteins which potentially obstruct CSF pathways. Prolonged raised pressures and free radical damage incur poor neurodevelopmental outcomes. The most common treatment involves permanent ventricular shunting with all its risks and consequences

Shotgun lipidomics and mass spectrometry imaging unveil diversity and dynamics in Gammarus fossarum lipid composition

Sentinel species are playing an indispensable role in monitoring environmental pollution in aquatic ecosystems. Many pollutants found in water prove to be endocrine disrupting chemicals that could cause disruptions in lipid homeostasis in aquatic species. A comprehensive profiling of the lipidome of these species is thus an essential step toward understanding the mechanism of toxicity induced by pollutants. Both the composition and spatial distribution of lipids in freshwater crustacean Gammarus fossarum were extensively examined herein. The baseline lipidome of gammarids of different sex and reproductive stages was established by high throughput shotgun lipidomics. Spatial lipid mapping by high resolution mass spectrometry imaging led to the discovery of sulfate-based lipids in hepato-pancreas and their accumulation in mature oocytes. A diverse and dynamic lipid composition in G. fossarum was uncovered, which deepens our understanding of the biochemical changes during development and which could serve as a reference for future ecotoxicological studies.Approches Protéomique et Lipidomique pour la compréhension des mécanismes moléculaires de toxicité en lien avec l'altération du métabolisme lipidique chez l'espèce sentinelle Gammarus fossarum durant le cycle de reproductio

MOA-2019-BLG-008Lb : a new microlensing detection of an object at the planet/brown dwarf boundary

Funding: R.A.S. and E.B. gratefully acknowledge support from NASA grant 80NSSC19K0291. Y.T. and J.W. acknowledge the support of DFG priority program SPP 1992 “Exploring the Diversity of Extrasolar Planets” (WA 1047/11-1). K.H. acknowledges support from STFC grant ST/R000824/1. J.C.Y. acknowledges support from NSF grant No. AST-2108414. Work by C.H. was supported by the grants of the National Research Foundation of Korea (2019R1A2C2085965 and 2020R1A4A2002885). D.M.B. acknowledges the support of the NYU Abu Dhabi Research Enhancement Fund under grant RE124. This work was partly supported by the National Science Foundation of China (grant Nos. 11333003, 11390372, and 11761131004 to S.M.). The MOA project is supported by JSPS KAKENHI grant Nos. JSPS24253004, JSPS26247023, JSPS23340064, JSPS15H00781, JP16H06287, and JP17H02871.We report on the observations, analysis and interpretation of the microlensing event MOA-2019-BLG-008. The observed anomaly in the photometric light curve is best described through a binary lens model. In this model, the source did not cross caustics and no finite-source effects were observed. Therefore, the angular Einstein ring radius θE cannot be measured from the light curve alone. However, the large event duration, tE ∼ 80 days, allows a precise measurement of the microlensing parallax πE. In addition to the constraints on the angular radius θ* and the apparent brightness Is of the source, we employ the Besançon and GalMod galactic models to estimate the physical properties of the lens. We find excellent agreement between the predictions of the two galactic models: the companion is likely a resident of the brown dwarf desert with a mass Mp ∼ 30 MJup, and the host is a main-sequence dwarf star. The lens lies along the line of sight to the Galactic bulge, at a distance of ≤4 kpc. We estimate that in about 10 yr the lens and source will be separated by ∼55 mas, and it will be possible to confirm the exact nature of the lensing system by using high-resolution imaging from ground- or space-based observatories.Publisher PDFPeer reviewe

Treatments for people who use anabolic androgenic steroids: a scoping review.

BACKGROUND: A growing body of evidence suggests that anabolic androgenic steroids (AAS) are used globally by a diverse population with varying motivations. Evidence has increased greatly in recent years to support understanding of this form of substance use and the associated health harms, but there remains little evidence regarding interventions to support cessation and treat the consequences of use. In this scoping review, we identify and describe what is known about interventions that aim to support and achieve cessation of AAS, and treat and prevent associated health problems. METHODS: A comprehensive search strategy was developed in four bibliographic databases, supported by an iterative citation searching process to identify eligible studies. Studies of any psychological or medical treatment interventions delivered in response to non-prescribed use of AAS or an associated harm in any setting were eligible. RESULTS: In total, 109 eligible studies were identified, which included case reports representing a diverse range of disciplines and sources. Studies predominantly focussed on treatments for harms associated with AAS use, with scant evidence on interventions to support cessation of AAS use or responding to dependence. The types of conditions requiring treatment included psychiatric, neuroendocrine, hepatic, kidney, cardiovascular, musculoskeletal and infectious. There was limited evidence of engagement with users or delivery of psychosocial interventions as part of treatment for any condition, and of harm reduction interventions initiated alongside, or following, treatment. Findings were limited throughout by the case report study designs and limited information was provided. CONCLUSION: This scoping review indicates that while a range of case reports describe treatments provided to AAS users, there is scarce evidence on treating dependence, managing withdrawal, or initiating behaviour change in users in any settings. Evidence is urgently required to support the development of effective services for users and of evidence-based guidance and interventions to respond to users in a range of healthcare settings. More consistent reporting in articles of whether engagement or assessment relating to AAS was initiated, and publication within broader health- or drug-related journals, will support development of the evidence base

A Super-Earth and Sub-Neptune Transiting the Late-type M Dwarf LP 791-18

Planets occur most frequently around cool dwarfs, but only a handful of specific examples are known to orbit the latest-type M stars. Using TESS photometry, we report the discovery of two planets transiting the low-mass star called LP 791-18 (identified by TESS as TOI 736). This star has spectral type M6V, effective temperature 2960 K, and radius 0.17 R o, making it the third-coolest star known to host planets. The two planets straddle the radius gap seen for smaller exoplanets; they include a 1.1R ⊕ planet on a 0.95 day orbit and a 2.3R ⊕ planet on a 5 day orbit. Because the host star is small the decrease in light during these planets' transits is fairly large (0.4% and 1.7%). This has allowed us to detect both planets' transits from ground-based photometry, refining their radii and orbital ephemerides. In the future, radial velocity observations and transmission spectroscopy can both probe these planets' bulk interior and atmospheric compositions, and additional photometric monitoring would be sensitive to even smaller transiting planets

TESS Discovery of an Ultra-short-period Planet around the Nearby M Dwarf LHS 3844

Data from the newly commissioned Transiting Exoplanet Survey Satellite has revealed a 'hot Earth' around LHS 3844, an M dwarf located 15 pc away. The planet has a radius of R ⊕ and orbits the star every 11 hr. Although the existence of an atmosphere around such a strongly irradiated planet is questionable, the star is bright enough (I = 11.9, K = 9.1) for this possibility to be investigated with transit and occultation spectroscopy. The star's brightness and the planet's short period will also facilitate the measurement of the planet's mass through Doppler spectroscopy