Accelerometer assessed moderate-to-vigorous physical activity and successful ageing: results from the Whitehall II study.

Physical activity is key for successful ageing, but questions remain regarding the optimal physical activity pattern. We examined the cross-sectional association between physical activity and successful ageing using data on 3,749 participants (age range = 60-83years) of the Whitehall II study. The participants underwent a clinical assessment, completed a 20-item physical activity questionnaire, and wore a wrist-mounted accelerometer for 9 days. Successful ageing was defined as good cognitive, motor, and respiratory functioning, along with absence of disability, mental health problems, and major chronic diseases. Time spent in moderate-to-vigorous physical activity (MVPA) episodes assessed by accelerometer was classified as "short" (1-9.59 minutes) and "long" (≥10 minutes) bouts. Linear multivariate regression showed that successful agers (N = 789) reported 3.79 (95% confidence interval (CI): 1.39-6.19) minutes more daily MVPA than other participants. Accelerometer data showed this difference to be 3.40 (95% CI:2.44-4.35) minutes for MVPA undertaken in short bouts, 4.16 (95% CI:3.11-5.20) minutes for long bouts, and 7.55 (95% CI:5.86-9.24) minutes for all MVPA bouts lasting 1 minute or more. Multivariate logistic regressions showed that participants undertaking ≥150 minutes of MVPA per week were more likely to be successful agers with both self-reported (Odd Ratio (OR) = 1.29,95% (CI):1.09-1.53) and accelerometer data (length bout ≥1 minute:OR = 1.92, 95%CI:1.60-2.30). Successful agers practice more MVPA, having both more short and long bouts, than non-successful agers

Protective effect of Atriplex halimus extract against benzene-induced haematotoxicity in rats

Benzen (BZ) is a ubiquitous environmental pollutant with a toxic effect mainly aimed at the hematopoietic­ and immune systems. Atriplex halimus L. (Amaranthaceae) is a Mediterranean halophytic shrub traditionally used in North Africa as medicinal plant for several therapeutic uses. The present study aimed to estimate the preventive and curative effects of Atriplex halimus L. (Ah) aqueous extract against BZ-induced hematotoxici­ty in rats. Analysis of the extract by the method of LC-MS revealed the presence of 7 vitamins, among which vitamin C content was the highest. Adult rats were divided into five groups as follow: Group 1 received water (control); Group 2 received orally Ah aqueous extract (200 mg/kg) 3 days/week for 15 weeks; Group 3 received BZ (100 mg/kg b.w) daily in drinking water for 15 weeks; Group 4 received concomitantly BZ (100 mg/kg) and preventive treatment with Ah (200 mg/kg) for 15 weeks (AhP+BZ); Group 5 first received BZ (100 mg/kg) for 11 weeks and then curative treatment with Ah extract (300 mg/kg) daily for 30 days (BZ+AhC). It was shown that sub-chronic exposure to benzene induced leukopenia, lymphocytopenia, granulocytopenia and massive degeneration of the bone marrow tissue. The level of GSH and activity of GST and CAT were significantly lowered and the level of MDA was increased in the blood and bone marrow in rats of BZ-intoxicated group compared to the control rats. Administration of Ah extract recovered the bone marrow structure, dramatically decreased MDA content and increased GSH and CAT activity and GST level in the blood and bone marrow as compared with the indices in BZ-treated group. These observations demonstrate that curative and, to a lesser extent, preventive treatment with Atriplex halimus extract have therapeutic potential against hematotoxicity induced by benzene

Home and Work Physical Activity Environments: Associations with Cardiorespiratory Fitness and Physical Activity Level in French Women

The influence of the physical activity environment in the home and at work on cardiorespiratory fitness (CRF) and objectively-measured physical activity has not been extensively studied. We recruited 147 women with a (mean ± SD) age of 54 ± 7 years and without evidence of chronic disease. The physical activity environment was assessed by self-report (Assessing Levels of PHysical Activity or ALPHA questionnaire), CRF using a submaximal step test, usual physical activity using combined heart rate and accelerometry, as well as by a validated questionnaire (Recent Physical Activity Questionnaire). Summary scores of the home environment and the work environment derived from the ALPHA questionnaire were positively correlated with CRF after adjustment for age ($r$ = 0.18, $p$ = 0.03 and $r$ = 0.28, $p$ < 0.01, respectively). Women owning a bicycle or having a garden (which may prompt physical activity) had higher CRF; those with a bicycle at home also had a higher physical activity energy expenditure. Similarly, women who had access to fitness equipment at work had higher CRF. In conclusion, these results provide new insights into potential environmental influences on physical capacity and physical activity that could inform the design of physical activity promotion strategies.European Union (Integrated Project LSHM-CT-2006-037197 in the Framework Programme 6 of the European Community), Medical Research Council (Grant ID: MC_UU_12015/3

A new corpus for the evaluation of arabic intrinsic plagiarism detection

The final publication is available at Springer via http://dx.doi.org/10.1007/978-3-642-40802-1_6The present paper introduces the first corpus for the evaluation of Arabic intrinsic plagiarism detection. The corpus consists of 1024 artificial suspicious documents in which 2833 plagiarism cases have been inserted automatically from source documentsThis work is the result of the collaboration in the framework of the bilateral research project AECID-PCI AP/043848/11 (Application of Natural Language Processing to the Need of the University) between the Universitat Politècnica de València in Spain and Constantine 2 University in AlgeriaBensalem, I.; Rosso, P.; Chikhi, S. (2013). A new corpus for the evaluation of arabic intrinsic plagiarism detection. En Information Access Evaluation. Multilinguality, Multimodality, and Visualization. Springer Verlag (Germany). 53-58. https://doi.org/10.1007/978-3-642-40802-1_6S5358Springer Policy on Publishing Integrity. Guidelines for Journal EditorsPotthast, M., Stein, B., Eiselt, A., Barrón-Cedeño, A., Rosso, P.: Overview of the 1st International Competition on Plagiarism Detection. In: Stein, B., Rosso, P., Stamatatos, E., Koppel, M., Agirre, E. (eds.) SEPLN 2009 Workshop on Uncovering Plagiarism, Authorship, and Social Software Misuse (PAN 2009), pp. 1–9 (2009)Potthast, M., Stein, B., Barrón-Cedeño, A., Rosso, P.: An Evaluation Framework for Plagiarism Detection. In: Huang, C.-R., Jurafsky, D. (eds.) Proceedings of the 23rd International Conference on Computational Linguistics (COLING 2010), pp. 997–1005. ACL (2010)Potthast, M., Barrón-cedeño, A., Eiselt, A., Stein, B., Rosso, P.: Overview of the 2nd International Competition on Plagiarism Detection. In: Braschler, M., Harman, D. (eds.) Notebook Papers of CLEF 2010 LABs and Workshops (2010)Potthast, M., Eiselt, A., Barrón-Cedeño, A., Stein, B., Rosso, P.: Overview of the 3rd International Competition on Plagiarism Detection. In: Petras, V., Forner, P., Clough, P. (eds.) Notebook Papers of CLEF 2011 LABs and Workshops (2011)Potthast, M., Gollub, T., Hagen, M., Graßegger, J., Kiesel, J., Michel, M., Oberländer, A., Tippmann, M., Barrón-Cedeño, A., Gupta, P., Rosso, P., Stein, B.: Overview of the 4th International Competition on Plagiarism Detection. In: Forner, P., Karlgren, J., Womser-Hacker, C. (eds.) CLEF 2012 Evaluation Labs and Workshop –Working Notes Papers (2012)Juola, P.: An Overview of the Traditional Authorship Attribution Subtask Notebook for PAN at CLEF 2012. In: Forner, P., Karlgren, J., and Womser-Hacker, C. (eds.) CLEF 2012 Evaluation Labs and Workshop –Working Notes Papers (2012)Yakout, M.M.: Examples of Plagiarism in Scientific and Cultural Communities (in Arabic), http://www.yaqout.net/ba7s_4.htmlAbbasi, A., Chen, H.: Applying Authorship Analysis to Arabic Web Content. In: Kantor, P., Muresan, G., Roberts, F., Zeng, D.D., Wang, F.-Y., Chen, H., Merkle, R.C. (eds.) ISI 2005. LNCS, vol. 3495, pp. 183–197. Springer, Heidelberg (2005)Shaker, K., Corne, D.: Authorship Attribution in Arabic using a hybrid of evolutionary search and linear discriminant analysis. In: 2010 UK Workshop on Computational Intelligence (UKCI), pp. 1–6. IEEE (2010)Ouamour, S., Sayoud, H.: Authorship attribution of ancient texts written by ten arabic travelers using a SMO-SVM classifier. In: 2012 International Conference on Communications and Information Technology (ICCIT), pp. 44–47. IEEE (2012)Bensalem, I., Rosso, P., Chikhi, S.: Intrinsic Plagiarism Detection in Arabic Text: Preliminary Experiments. In: Berlanga, R., Rosso, P. (eds.) 2nd Spanish Conference on Information Retrieval (CERI 2012), Valencia (2012)Jadalla, A., Elnagar, A.: A Plagiarism Detection System for Arabic Text-Based Documents. In: Chau, M., Wang, G.A., Yue, W.T., Chen, H. (eds.) PAISI 2012. LNCS, vol. 7299, pp. 145–153. Springer, Heidelberg (2012)Alzahrani, S., Salim, N.: Statement-Based Fuzzy-Set Information Retrieval versus Fingerprints Matching for Plagiarism Detection in Arabic Documents. In: 5th Postgraduate Annual Research Seminar (PARS 2009), Johor Bahru, Malaysia, pp. 267–268 (2009)Menai, M.E.B.: Detection of Plagiarism in Arabic Documents. International Journal of Information Technology and Computer Science 10, 80–89 (2012)Jaoua, M., Jaoua, F.K., Hadrich Belguith, L., Ben Hamadou, A.: Automatic Detection of Plagiarism in Arabic Documents Based on Lexical Chains. Arab Computer Society Journal 4, 1–11 (2011) (in Arabic)Potthast, M., Hagen, M., Völske, M., Stein, B.: Crowdsourcing Interaction Logs to Understand Text Reuse from the Web. In: 51st Annual Meeting of the Association of Computational Linguistics (ACL 2013). ACM (to appear, 2013)Stein, B., Lipka, N., Prettenhofer, P.: Intrinsic plagiarism analysis. Language Resources and Evaluation 45, 63–82 (2010)Bensalem, I., Rosso, P., Chikhi, S.: Building Arabic Corpora from Wikisource. In: 10th ACS/IEEE International Conference on Computer Systems and Applications (AICCSA 2013). IEEE (2013

Supporting ethical, independent learning behavior among university students in the Arabian Gulf

© Springer International Publishing Switzerland 2014. Students in the Arabian Gulf region and the world over confront plagiarism temptations wittingly or unwittingly due to the multitude of free and easily available electronic sources of information. Rather than develop independent learning skills and academic integrity, students are often taken advantage of by essay mills that sell readymade essays. Instructors at times compound the problem by repeatedly recycling course assignments and tasks. Furthermore, there have been reports of the use of social networking sites for outsourcing and contract cheating in student assignments. This paper discusses how educators in an institution of higher learning in the UAE assist students to develop good academic skills. Data collection is with the use of an online survey questionnaire. Concurring with Wheeler and Anderson (2010) who call for appropriate and comprehensive institutional policies and guidelines for dealing with plagiarism, practical examples of the processes and procedures used at these institutions are provided

A systematic review of correlates of sedentary behaviour in adults aged 18–65 years: a socio-ecological approach

Background: Recent research shows that sedentary behaviour is associated with adverse cardio-metabolic consequences even among those considered sufficiently physically active. In order to successfully develop interventions to address this unhealthy behaviour, factors that influence sedentariness need to be identified and fully understood. The aim of this review is to identify individual, social, environmental, and policy-related determinants or correlates of sedentary behaviours among adults aged 18-65 years. Methods: PubMed, Embase, CINAHL, PsycINFO and Web of Science were searched for articles published between January 2000 and September 2015. The search strategy was based on four key elements and their synonyms: (a) sedentary behaviour (b) correlates (c) types of sedentary behaviours (d) types of correlates. Articles were included if information relating to sedentary behaviour in adults (18-65 years) was reported. Studies on samples selected by disease were excluded. The full protocol is available from PROSPERO (PROSPERO 2014:CRD42014009823). Results: 74 original studies were identified out of 4041: 71 observational, two qualitative and one experimental study. Sedentary behaviour was primarily measured as self-reported screen leisure time and total sitting time. In 15 studies, objectively measured total sedentary time was reported: accelerometry (n = 14) and heart rate (n = 1). Individual level factors such as age, physical activity levels, body mass index, socio-economic status and mood were all significantly correlated with sedentariness. A trend towards increased amounts of leisure screen time was identified in those married or cohabiting while having children resulted in less total sitting time. Several environmental correlates were identified including proximity of green space, neighbourhood walkability and safety and weather. Conclusions: Results provide further evidence relating to several already recognised individual level factors and preliminary evidence relating to social and environmental factors that should be further investigated. Most studies relied upon cross-sectional design limiting causal inference and the heterogeneity of the sedentary measures prevented direct comparison of findings. Future research necessitates longitudinal study designs, exploration of policy-related factors, further exploration of environmental factors, analysis of inter-relationships between identified factors and better classification of sedentary behaviour domains

Maternal cadmium, iron and zinc levels, DNA methylation and birth weight

Background Cadmium (Cd) is a ubiquitous and environmentally persistent toxic metal that has been implicated in neurotoxicity, carcinogenesis and obesity and essential metals including zinc (Zn) and iron (Fe) may alter these outcomes. However mechanisms underlying these relationships remain limited. Methods We examined whether maternal Cd levels during early pregnancy were associated with offspring DNA methylation at regulatory sequences of genomically imprinted genes and weight at birth, and whether Fe and Zn altered these associations. Cd, Fe and Zn were measured in maternal blood of 319 women ≤12 weeks gestation. Offspring umbilical cord blood leukocyte DNA methylation at regulatory differentially methylated regions (DMRs) of 8 imprinted genes was measured using bisulfite pyrosequencing. Regression models were used to examine the relationships among Cd, Fe, Zn, and DMR methylation and birth weight. Results Elevated maternal blood Cd levels were associated with lower birth weight (p = 0.03). Higher maternal blood Cd levels were also associated with lower offspring methylation at the PEG3 DMR in females (β = 0.55, se = 0.17, p = 0.05), and at the MEG3 DMR in males (β = 0.72, se = 0.3, p = 0.08), however the latter association was not statistically significant. Associations between Cd and PEG3 and PLAGL1 DNA methylation were stronger in infants born to women with low concentrations of Fe (p < 0.05). Conclusions Our data suggest the association between pre-natal Cd and offspring DNA methylation at regulatory sequences of imprinted genes may be sex- and gene-specific. Essential metals such as Zn may mitigate DNA methylation response to Cd exposure. Larger studies are required

A data-driven, meaningful, easy to interpret, standardised accelerometer outcome variable for global surveillance

This is the author accepted manuscript. The final version is available from Elsevier via the DOI in this record.Objectives: Our aim is to demonstrate how a data-driven accelerometer metric, the acceleration above which a person’s most active minutes are accumulated, can a) quantify the prevalence of meeting current physical activity guidelines for global surveillance and b) moving forward, could inform accelerometer-driven physical activity guidelines. Unlike cut-point methods, the metric is population-independent (e.g. age) and potentially comparable across datasets. Design: Cross-sectional, secondary data analysis. Methods: Analyses were carried out on five datasets using wrist-worn accelerometers: children (N=145), adolescent girls (N=1669), office workers (N=114), pre- (N=1218) and post- (N=1316) menopausal women, and adults with type 2 diabetes (N=475). Open-source software (GGIR) was used to generate the magnitude of acceleration above which a person’s most active 60, 30 and 2 minutes are accumulated: M60ACC; M30ACC and M2ACC, respectively. Results: The proportion of participants with M60ACC (children) and M30ACC (adults) values higher than accelerations representative of brisk walking (i.e., moderate-to-vigorous physical activity) ranged from 17-68% in children and 15%-81% in adults, tending to decline with age. The proportion of pre-and postmenopausal women with M2ACC values meeting thresholds for bone health ranged from 6-13%. Conclusions: These metrics can be used for global surveillance of physical activity, including assessing prevalence of meeting current physical activity guidelines. As accelerometer and corresponding health data accumulate it will be possible to interpret the metrics relative to age- and sex- specific norms and derive evidence-based physical activity guidelines directly from accelerometer data for use in future global surveillance. This is where the potential advantages of these metrics lie