4,986 research outputs found
Self-supervised learning: When is fusion of the primary and secondary sensor cue useful?
Self-supervised learning (SSL) is a reliable learning mechanism in which a
robot enhances its perceptual capabilities. Typically, in SSL a trusted,
primary sensor cue provides supervised training data to a secondary sensor cue.
In this article, a theoretical analysis is performed on the fusion of the
primary and secondary cue in a minimal model of SSL. A proof is provided that
determines the specific conditions under which it is favorable to perform
fusion. In short, it is favorable when (i) the prior on the target value is
strong or (ii) the secondary cue is sufficiently accurate. The theoretical
findings are validated with computational experiments. Subsequently, a
real-world case study is performed to investigate if fusion in SSL is also
beneficial when assumptions of the minimal model are not met. In particular, a
flying robot learns to map pressure measurements to sonar height measurements
and then fuses the two, resulting in better height estimation. Fusion is also
beneficial in the opposite case, when pressure is the primary cue. The analysis
and results are encouraging to study SSL fusion also for other robots and
sensors
Unveiling electrotransformation of Moraxella catarrhalis as a process of natural transformation
The human respiratory tract pathogen Moraxella catarrhalis is a naturally competent microorganism. However, electrotransformation has long been used to introduce foreign DNA into this organism. This study demonstrated that electrotransformants obtained with linear or circular nonreplicating plasmid DNA originated exclusively from natural transformation processes taking place during the recovery phase after the application of current. Only replicating plasmid DNA could be introduced into M. catarrhalis by electrotransformation, in a type IV pilus-independent manner. Electrotransformation with homologous genomic DNA indicated that restriction of double-stranded DNA was independent of type III restriction-methylation systems. Nontransformability of M. catarrhalis by electrotransformation was observed using double- as well as single-stranded DNA. In addition, the study showed that natural competence is a very constant feature of M. catarrhali
Trunk sway in mildly disabled multiple sclerosis patients with and without balance impairment
Multiple sclerosis (MS) causes a broad range of neurological symptoms. Most common is poor balance control. However, knowledge of deficient balance control in mildly affected MS patients who are complaining of balance impairment but have normal clinical balance tests (CBT) is limited. This knowledge might provide insights into the normal and pathophysiological mechanisms underlying stance and gait. We analysed differences in trunk sway between mildly disabled MS patients with and without subjective balance impairment (SBI), all with normal CBT. The sway was measured for a battery of stance and gait balance tests (static and dynamic posturography) and compared to that of age- and sex-matched healthy subjects. Eight of 21 patients (38%) with an Expanded Disability Status Scale of 1.0-3.0 complained of SBI during daily activities. For standing on both legs with eyes closed on a normal and on a foam surface, patients in the no SBI group showed significant differences in the range of trunk roll (lateral) sway angle and velocity, compared to normal persons. Patients in the SBI group had significantly greater lateral sway than the no SBI group, and sway was also greater than normal in the pitch (anterior-posterior) direction. Sway for one-legged stance on foam was also greater in the SBI group compared to the no SBI and normal groups. We found a specific laterally directed impairment of balance in all patients, consistent with a deficit in proprioceptive processing, which was greater in the SBI group than in the no SBI group. This finding most likely explains the subjective symptoms of imbalance in patients with MS with normal CBT
[S IV] in the NGC 5253 Supernebula: Ionized Gas Kinematics at High Resolution
The nearby dwarf starburst galaxy NGC 5253 hosts a deeply embedded
radio-infrared supernebula excited by thousands of O stars. We have observed
this source in the 10.5{\mu}m line of S+3 at 3.8 kms-1 spectral and 1.4"
spatial resolution, using the high resolution spectrometer TEXES on the IRTF.
The line profile cannot be fit well by a single Gaussian. The best simple fit
describes the gas with two Gaussians, one near the galactic velocity with FWHM
33.6 km s-1 and another of similiar strength and FWHM 94 km s-1 centered \sim20
km s-1 to the blue. This suggests a model for the supernebula in which gas
flows towards us out of the molecular cloud, as in a "blister" or "champagne
flow" or in the HII regions modelled by Zhu (2006).Comment: Accepted for publication in the Astrophysical Journal 4 June 201
Design verification of the gyrotron diamond output window for the upgrade of the ECRH system at W7-X
The 10 MW electron cyclotron resonance heating (ECRH) system at the stellarator Wendelstein 7-X (W7-X) currently relies on the successful operation of continuous wave (CW) 1 MW, 140 GHz gyrotrons which have chemical vapor deposition (CVD) diamond output windows cooled by the industrial silicon oil Dow Corning 200(R) 5 cSt. The window features a 1.8 mm thick diamond disk brazed to two copper cuffs with an aperture of 88 mm, which are then integrated in a steel housing. In the context of the upgrade of the ECRH system towards higher microwave power, this gyrotron design has been significantly advanced to fulfill the requirement of 1.5 MW CW operation, still at 140 GHz. A prototype of this new gyrotron is under development at Thales, France. This paper reports the computational fluid dynamics (CFD) conjugated heat transfer and structural analyses of the diamond window performed using the commercial code ANSYS V19.2 to investigate its performance at 1.5 MW operation. Furthermore, sensitivity studies were also carried out with respect to the absorbed power in the disk and the mm-wave beam radius at the window location. These analyses showed that the window design of the existing 1 MW gyrotrons still works quite well at higher power operation, thus verifying the performance of the window. Even in the worst case scenario of 1.5 kW absorbed power, the maximum temperature of 215 °C at the disk center can be safely accepted, being below the conservative limit of 250 °C for CVD diamond. In addition, the non-axial symmetric thermal gradients due to the geometry of the cooling channels lead to thermal stresses in the disk and the cuffs. However, they are much lower than the limits. The copper cuffs experience plasticity deformation in the region of the interface with the diamond disk up to a value of about 1.5 mm
A New Type of Proton Coordination in an F1Fo-ATP Synthase Rotor Ring
The high-resolution structure of the rotor ring from alkaliphilic Bacillus pseudofirmus OF4 reveals a new type of ion binding in F1Fo-ATP synthases
Studies of the horizontal inhomogeneities in NO2 concentrations above a shipping lane using ground-based multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements and validation with airborne imaging DOAS measurements
This study describes a novel application of an “onion-peeling” approach to multi-axis differential optical absorption spectroscopy (MAX-DOAS) measurements of shipping emissions aiming at investigating the strong horizontal inhomogeneities in NO2 over a shipping lane. To monitor ship emissions on the main shipping route towards the port of Hamburg, a two-channel (UV and visible) MAX-DOAS instrument was deployed on the island Neuwerk in the German Bight, 6–7 km south of the main shipping lane. Utilizing the fact that the effective light path length in the atmosphere depends systematically on wavelength, simultaneous measurements and DOAS retrievals in the UV and visible spectral ranges are used to probe air masses at different horizontal distances to the instrument to estimate two-dimensional pollutant distributions. Two case studies have been selected to demonstrate the ability to derive the approximate plume positions in the observed area. A situation with northerly wind shows high NO2 concentrations close to the measurement site and low values in the north of the shipping lane. The opposite situation with southerly wind, unfavorable for the on-site in situ instrumentation, demonstrates the ability to detect enhanced NO2 concentrations several kilometers away from the instrument. Using a Gaussian plume model, in-plume NO2 volume mixing ratios can be derived from the MAX-DOAS measurements.
For validation, a comparison to airborne imaging DOAS measurements during the NOSE campaign in July 2013 is performed, showing good agreement between the approximate plume position derived from the onion-peeling MAX-DOAS and the airborne measurements as well as between the derived in-plume NO2 volume mixing ratios (VMRs)
Capacity-Speed Relationships in Prefrontal Cortex
Working memory (WM) capacity and WM processing speed are simple cognitive measures that underlie human performance in complex processes such as reasoning and language comprehension. These cognitive measures have shown to be interrelated in behavioral studies, yet the neural mechanism behind this interdependence has not been elucidated. We have carried out two functional MRI studies to separately identify brain regions involved in capacity and speed. Experiment 1, using a block-design WM verbal task, identified increased WM capacity with increased activity in right prefrontal regions, and Experiment 2, using a single-trial WM verbal task, identified increased WM processing speed with increased activity in similar regions. Our results suggest that right prefrontal areas may be a common region interlinking these two cognitive measures. Moreover, an overlap analysis with regions associated with binding or chunking suggest that this strategic memory consolidation process may be the mechanism interlinking WM capacity and WM speed.National Center for Research Resources (U.S.) (grant UL1RR025011)National Institutes of Health (U.S.) (grant NIH RO1 DC05375)Wallace H. Coulter FoundationNational Institute of Mental Health (U.S.) (Challenge Grant RC1MH090912-01
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