Confinamiento y ejercicio. Estrategias audiovisuales contra el sedentarismo.

El confinamiento ha dejado al descubierto los riesgos del teletrabajo para la salud: sedentarismo, estrés, depresión, etc. Según numerosos estudios estos problemas pueden mitigarse incorporando actividad física a la rutina diaria. El presente artículo recoge una propuesta creativa de acción basada en el análisis y la experiencia de uso de estrategias audiovisuales para incentivar los hábitos de actividad física. El objetivo es proponer una estrategia ‘gamificada’ de ejercicio físico que pueda resultar amena y fácil de implementar en nuestro día. Es una relación problema-solución basada en estudios para combatir el sedentarismo, el repaso de algunas estrategias y la práctica con la estrategia elegida. El videojuego activo Ring Fit Adventure combina los beneficios para la salud física y mental con el desarrollo de capacidades que aporta la práctica de videojuegos. Por esto se presenta como una propuesta interesante para ayudar a reducir el sedentarismo, y con ello, los niveles de estrés y depresión.post-print607 K

Follow-up and feedback processes in the EHEA

In the present paper, we describe the work being carried out by a group of professors so as to implement the follow-up and feedback processes of the activities students do throughout the first academic years in their Engineering studies. Not to mention, this project is within the EHEA (European Higher Education Area) framework. Our results show that these processes are key to enhance students learning, they can also have an impact in their academic performance and can be optimized in such a way that professors can assume the time it requires.Peer Reviewe

El Puzle i l'aprenentatge de la programació

Es descriu una experiència formalitzada d’aprenentatge cooperatiu mitjançant la utilització de la metodologia del puzle. Concretament, s’utilitza el puzle com una eina de suport en una assignatura organitzada d’acord amb l’estratègia de l’aprenentatge basat en projectes. La metodologia del puzle s’ha aplicat a tots els grups de les assignatures següents des del curs 2004-2005: 1. Enginyeria Tècnica de Telecomunicació, Introducció als Computadors (Q1 de primer curs, 4,5 crèdits) i Laboratori de Programació (Q2 de primer curs, 4,5 crèdits), i 2. Graus en Enginyeria de Sistemes de Telecomunicació i en Enginyeria Telemàtica, Introducció als Ordinadors (Q1 de primer curs, 6 crèdits ECTS) i Projecte de Programació (Q2 de primer curs, 6 crèdits ECTS). Com a part d’assignatures basades en l’aprenentatge basat en projectes es va començar a experimentar en dues assignatures a l’Escola d'Enginyeria de Telecomunicació i Aeroespacial de Castelldefels (EETAC), en el marc de les proves pilot d’adaptació de titulacions a l'espai europeu d'educació superior (EEES), impulsades per l’antic Departament d'Universitats, Recerca i Societat de la Informació (DURSI) de la Generalitat de Catalunya. Posteriorment es va seguir aplicant aquest model en els nous graus. Aquests anys d’experimentació ens han proporcionat una bona quantitat de resultats i conclusions.Peer Reviewe

VISMapper: ultra-fast exhaustive cartography of viral insertion sites for gene therapy

Background -- The possibility of integrating viral vectors to become a persistent part of the host genome makes them a crucial element of clinical gene therapy. However, viral integration has associated risks, such as the unintentional activation of oncogenes that can result in cancer. Therefore, the analysis of integration sites of retroviral vectors is a crucial step in developing safer vectors for therapeutic use. Results -- Here we present VISMapper, a vector integration site analysis web server, to analyze next-generation sequencing data for retroviral vector integration sites. VISMapper can be found at: http://vismapper.babelomics.org. Conclusions -- Because it uses novel mapping algorithms VISMapper is remarkably faster than previous available programs. It also provides a useful graphical interface to analyze the integration sites found in the genomic context

The Raman Laser Spectrometer for the ExoMars Rover Mission to Mars

The Raman Laser Spectrometer (RLS) on board the ESA/Roscosmos ExoMars 2020 mission will provide precise identification of the mineral phases and the possibility to detect organics on the Red Planet. The RLS will work on the powdered samples prepared inside the Pasteur analytical suite and collected on the surface and subsurface by a drill system. Raman spectroscopy is a well-known analytical technique based on the inelastic scattering by matter of incident monochromatic light (the Raman effect) that has many applications in laboratory and industry, yet to be used in space applications. Raman spectrometers will be included in two Mars rovers scheduled to be launched in 2020. The Raman instrument for ExoMars 2020 consists of three main units: (1) a transmission spectrograph coupled to a CCD detector; (2) an electronics box, including the excitation laser that controls the instrument functions; and (3) an optical head with an autofocus mechanism illuminating and collecting the scattered light from the spot under investigation. The optical head is connected to the excitation laser and the spectrometer by optical fibers. The instrument also has two targets positioned inside the rover analytical laboratory for onboard Raman spectral calibration. The aim of this article was to present a detailed description of the RLS instrument, including its operation on Mars. To verify RLS operation before launch and to prepare science scenarios for the mission, a simulator of the sample analysis chain has been developed by the team. The results obtained are also discussed. Finally, the potential of the Raman instrument for use in field conditions is addressed. By using a ruggedized prototype, also developed by our team, a wide range of terrestrial analog sites across the world have been studied. These investigations allowed preparing a large collection of real, in situ spectra of samples from different geological processes and periods of Earth evolution. On this basis, we are working to develop models for interpreting analog processes on Mars during the mission. Key Words: Raman spectroscopy—ExoMars mission—Instruments and techniques—Planetary sciences—Mars mineralogy and geochemistry—Search for life on Mars. Astrobiology 17, 627–65

Elaboración participante de materiales accesibles cognitivamente para el itinerario de Imagen y Sonido en el Proyecto Liceo

En este proyecto se ha realizado una formación sobre accesibilidad cognitiva y videojuegos a diversos alumnados. Así mismo se han revisado y realizado propuestas de materiales del itinerario de Imagen y Sonido del proyecto Liceo. La metodología ha sido participante. Los resultados principales son las propuestas de los materiales revisados, los guiones para las narrativas de las historias de vida, 5 GDD y tres publicaciones en proceso

Colombian consensus recommendations for diagnosis, management and treatment of the infection by SARS-COV-2/ COVID-19 in health care facilities - Recommendations from expert´s group based and informed on evidence

La Asociación Colombiana de Infectología (ACIN) y el Instituto de Evaluación de Nuevas Tecnologías de la Salud (IETS) conformó un grupo de trabajo para desarrollar recomendaciones informadas y basadas en evidencia, por consenso de expertos para la atención, diagnóstico y manejo de casos de Covid 19. Estas guías son dirigidas al personal de salud y buscar dar recomendaciones en los ámbitos de la atención en salud de los casos de Covid-19, en el contexto nacional de Colombia

Spread of a SARS-CoV-2 variant through Europe in the summer of 2020.

Following its emergence in late 2019, the spread of SARS-CoV-21,2 has been tracked by phylogenetic analysis of viral genome sequences in unprecedented detail3–5. Although the virus spread globally in early 2020 before borders closed, intercontinental travel has since been greatly reduced. However, travel within Europe resumed in the summer of 2020. Here we report on a SARS-CoV-2 variant, 20E (EU1), that was identified in Spain in early summer 2020 and subsequently spread across Europe. We find no evidence that this variant has increased transmissibility, but instead demonstrate how rising incidence in Spain, resumption of travel, and lack of effective screening and containment may explain the variant’s success. Despite travel restrictions, we estimate that 20E (EU1) was introduced hundreds of times to European countries by summertime travellers, which is likely to have undermined local efforts to minimize infection with SARS-CoV-2. Our results illustrate how a variant can rapidly become dominant even in the absence of a substantial transmission advantage in favourable epidemiological settings. Genomic surveillance is critical for understanding how travel can affect transmission of SARS-CoV-2, and thus for informing future containment strategies as travel resumes. © 2021, The Author(s), under exclusive licence to Springer Nature Limited

Hyperoxemia and excess oxygen use in early acute respiratory distress syndrome : Insights from the LUNG SAFE study

Publisher Copyright: © 2020 The Author(s). Copyright: Copyright 2020 Elsevier B.V., All rights reserved.Background: Concerns exist regarding the prevalence and impact of unnecessary oxygen use in patients with acute respiratory distress syndrome (ARDS). We examined this issue in patients with ARDS enrolled in the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) study. Methods: In this secondary analysis of the LUNG SAFE study, we wished to determine the prevalence and the outcomes associated with hyperoxemia on day 1, sustained hyperoxemia, and excessive oxygen use in patients with early ARDS. Patients who fulfilled criteria of ARDS on day 1 and day 2 of acute hypoxemic respiratory failure were categorized based on the presence of hyperoxemia (PaO2 > 100 mmHg) on day 1, sustained (i.e., present on day 1 and day 2) hyperoxemia, or excessive oxygen use (FIO2 ≥ 0.60 during hyperoxemia). Results: Of 2005 patients that met the inclusion criteria, 131 (6.5%) were hypoxemic (PaO2 < 55 mmHg), 607 (30%) had hyperoxemia on day 1, and 250 (12%) had sustained hyperoxemia. Excess FIO2 use occurred in 400 (66%) out of 607 patients with hyperoxemia. Excess FIO2 use decreased from day 1 to day 2 of ARDS, with most hyperoxemic patients on day 2 receiving relatively low FIO2. Multivariate analyses found no independent relationship between day 1 hyperoxemia, sustained hyperoxemia, or excess FIO2 use and adverse clinical outcomes. Mortality was 42% in patients with excess FIO2 use, compared to 39% in a propensity-matched sample of normoxemic (PaO2 55-100 mmHg) patients (P = 0.47). Conclusions: Hyperoxemia and excess oxygen use are both prevalent in early ARDS but are most often non-sustained. No relationship was found between hyperoxemia or excessive oxygen use and patient outcome in this cohort. Trial registration: LUNG-SAFE is registered with ClinicalTrials.gov, NCT02010073publishersversionPeer reviewe