116 research outputs found
Increasing awareness of climate change with immersive virtual reality
Previous research has shown that immersive virtual reality (VR) is a suitable tool for visualizing the consequences of climate change. The aim of the present study was to investigate whether visualization in VR has a stronger influence on climate change awareness and environmental attitudes compared to traditional media. Furthermore, it was examined how realistic a VR experience has to be in order to have an effect. The VR experience consisted of a model of the Aletsch glacier (Switzerland) melting over the course of 220 years. Explicit measurements (new environmental paradigm NEP, climate change scepticism, and nature relatedness) and an implicit measurement (implicit association test) were collected before and after the VR intervention and compared to three different non-VR control conditions (video, images with text, and plain text). In addition, the VR environment was varied in terms of degrees of realism and sophistication (3 conditions: abstract visualization, less sophisticated realistic visualization, more sophisticated realistic visualization). The six experimental conditions (3 VR conditions, three control conditions) were modeled as mixed effects, with VR versus control used as a fixed effect in a mixed effects modeling framework. Across all six conditions, environmental awareness (NEP) was higher after the participants (N = 142) had been confronted with the glacier melting, while no differences were found for nature relatedness and climate change scepticism before and after the interventions. There was no significant difference between VR and control conditions for any of the four measurements. Nevertheless, contrast analyses revealed that environmental awareness increased significantly only for the VR but not for the control conditions, suggesting that VR is more likely to lead to attitude change. Our results show that exposure to VR environments successfully increased environmental awareness independently of the design choices, suggesting that even abstract and less sophisticated VR environment designs may be sufficient to increase pro-environmental attitudes
Bacterial growth in media mimicking the high salt and alkalinity of extreme kazakhstan environments results in production of antimicrobial compounds in soil actinomycetes isolated from these extremophile locations
Increasing antibiotic resistance among multidrug resistant pathogens necessitates the search for newer antimicrobials. Streptomyces historically produce the largest number of antibacterials and herein we describe isolation of antagonists from extremophiles using unusual culture media. Antagonists or antimicrobials produced under extremophile environmental conditions demonstrated activity against MRSA from Kazakhstan and the United States
Bacterial growth in media mimicking the high salt and alkalinity of extreme kazakhstan environments results in production of antimicrobial compounds in soil actinomycetes isolated from these extremophile locations
Increasing antibiotic resistance among multidrug resistant pathogens necessitates the search for newer antimicrobials. Streptomyces historically produce the largest number of antibacterials and herein we describe isolation of antagonists from extremophiles using unusual culture media. Antagonists or antimicrobials produced under extremophile environmental conditions demonstrated activity against MRSA from Kazakhstan and the United States
Dark costs, missing data: shedding some light on services trade
We develop a method to project missing sectoral services output and trade. For OECD countries, projected and observed output data match well. The basis is a structural gravity model to estimate barriers to services trade across sectors, countries and time. The model fits well and reveals key differences across service sectors. Border barriers fall over time but unevenly. Inferred border barriers are fitted to national geography, technology, income and endowments, and institutional determinants. The fitted model including fitted border barriers is used to project missing internal or bilateral trade flows, aggregating to projected output
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Modeling the influence of open water surfaces on the summertime temperature and thermal comfort in the city
Due to the combination of rapid global urbanization and climate change, urban climate issues are becoming relatively more important and are gaining interest. Compared to rural areas, the temperature in cities is higher (the urban heat island effect) due to the modifications in the surface radiation and energy balances. This study hypothesizes that the urban heat island can be mitigated by introducing open surface water in urban design. In order to test this, we use the WRF mesoscale meteorological model in which an idealized circular city is designed. Herein, the surface water cover, its size, spatial configuration, and temperature are varied. Model results indicate that the cooling effect of water bodies depends nonlinearly on the fractional water cover, size, and distribution of individual lakes within the city with respect to wind direction. Relatively large lakes show a high temperature effect close to their edges and in downwind areas. Several smaller lakes equally distributed within the urban area have a smaller temperature effect, but influence a larger area of the city. Evaporation from open water bodies may lower the temperature, but on the other hand also increases the humidity, which dampens the positive effect on thermal comfort. In addition, when the water is warmer than the air temperature (during autumn or night), the water body has an adverse effect on thermal comfort. In those cases, the water body eventually limits the cooling and thermal comfort in the surrounding city, and thus diverges from the original intention of the intervention
A proposed architecture and method of operation for improving the protection of privacy and confidentiality in disease registers
BACKGROUND: Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national identification number, or by ensembles of non-unique identifying data items, such as name, sex and date of birth. However, growing concern over the privacy and confidentiality aspects of disease registers may hinder their future operation. Technical solutions to these legitimate concerns are needed. DISCUSSION: An alternative method of operation is proposed which involves splitting the personal identifiers from the medical details at the source of notification, and separately encrypting each part using asymmetrical (public key) cryptographic methods. The identifying information is sent to a single Population Register, and the medical details to the relevant disease register. The Population Register uses probabilistic record linkage to assign a unique personal identification (UPI) number to each person notified to it, although not necessarily everyone in the entire population. This UPI is shared only with a single trusted third party whose sole function is to translate between this UPI and separate series of personal identification numbers which are specific to each disease register. SUMMARY: The system proposed would significantly improve the protection of privacy and confidentiality, while still allowing the efficient linkage of records between disease registers, under the control and supervision of the trusted third party and independent ethics committees. The proposed architecture could accommodate genetic databases and tissue banks as well as a wide range of other health and social data collections. It is important that proposals such as this are subject to widespread scrutiny by information security experts, researchers and interested members of the general public, alike
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Climate and more sustainable cities: climate information for improved planning and management of cities (producers/capabilities perspective)
In the last two decades substantial advances have been made in the understanding of the scientific basis of urban climates. These are reviewed here with attention to sustainability of cities, applications that use climate information, and scientific understanding in relation to measurements and modelling. Consideration is given from street (micro) scale to neighbourhood (local) to city and region (meso) scale. Those areas where improvements are needed in the next decade to ensure more sustainable cities are identified. High-priority recommendations are made in the following six strategic areas: observations, data, understanding, modelling, tools and education. These include the need for more operational urban measurement stations and networks; for an international data archive to aid translation of research findings into design tools, along with guidelines for different climate zones and land uses; to develop methods to analyse atmospheric data measured above complex urban surfaces; to improve short-range, high-resolution numerical prediction of weather, air quality and chemical dispersion through improved modelling of the biogeophysical features of the urban land surface; to improve education about urban meteorology; and to encourage communication across scientific disciplines at a range of spatial and temporal scales
Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion
Pseudomonas aeruginosa is a Gram-negative bacterial pathogen associated with acute and chronic
infections. The universal c-di-GMP second messenger is instrumental in the switch from a motile
lifestyle to resilient biofilm as in the cystic fibrosis lung. The SadC diguanylate cyclase is
associated with this patho-adaptive transition. Here we identified an unrecognized SadC partner,
WarA, which we show is a methyltransferase in complex with a putative kinase WarB. We
established that WarA binds to c-di-GMP, which potentiates its methyltransferase activity.
Together, WarA and WarB have structural similarities with the bi-functional Escherichia coli LPS
O antigen regulator WbdD. Strikingly, WarA influences P. aeruginosa O antigen modal
distribution and interacts with the LPS biogenesis machinery. LPS is known to modulate the
immune response in the host, and by using a zebrafish infection model, we implicate WarA in the
ability of P. aeruginosa to evade detection by the host.BBSRC & Wellcome Trus
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