mejora continua del proceso de electrospining por medio del análisis de procesos: caso de estudio CU UAEM Valle de México

Se tiene como misión el innovar e implementar nuevas tecnologías con conocimientos adquiridos de nuestra formación, aplicándolo en el desarrollo de la máquina de electrospínning. Iniciamos por la producción de biotecnología con la preparación y proceso de la solución de Difluoruro de Polivinilideno (PVDF) con el diluyente Dimetilformamida (DMF). Este proceso se emplea a alto voltaje realizando un campo electrostático, este atraerá partículas de la solución o fluido polimérico formando un cono inyector hacia una superficie recolectora la cual formara y solidificara partículas micro y nanofibras, las cuales formaran membranas.Its mission is to improve, create, innovate and implement new technologies with the knowledge acquired from our training, applying it in the development of the electrospinning machine. In this case we started with the production of biotechnology with respect to the preparation and processing of the solution of Polyvinylidene Difluoride (PVDF) with a thinner material such as Dimethylformamide (DMF), as well as the construction of a prototype electrospinning machine.This process employs high voltage for an electrostatic field, which will attract particles from the solution or polymeric fluid thus forming an injector cone towards a collecting surface which will form and solidify micro and nanofibres particles, which in turn will form membrane

Effects of eight neuropsychiatric copy number variants on human brain structure

Many copy number variants (CNVs) confer risk for the same range of neurodevelopmental symptoms and psychiatric conditions including autism and schizophrenia. Yet, to date neuroimaging studies have typically been carried out one mutation at a time, showing that CNVs have large effects on brain anatomy. Here, we aimed to characterize and quantify the distinct brain morphometry effects and latent dimensions across 8 neuropsychiatric CNVs. We analyzed T1-weighted MRI data from clinically and non-clinically ascertained CNV carriers (deletion/duplication) at the 1q21.1 (n = 39/28), 16p11.2 (n = 87/78), 22q11.2 (n = 75/30), and 15q11.2 (n = 72/76) loci as well as 1296 non-carriers (controls). Case-control contrasts of all examined genomic loci demonstrated effects on brain anatomy, with deletions and duplications showing mirror effects at the global and regional levels. Although CNVs mainly showed distinct brain patterns, principal component analysis (PCA) loaded subsets of CNVs on two latent brain dimensions, which explained 32 and 29% of the variance of the 8 Cohen’s d maps. The cingulate gyrus, insula, supplementary motor cortex, and cerebellum were identified by PCA and multi-view pattern learning as top regions contributing to latent dimension shared across subsets of CNVs. The large proportion of distinct CNV effects on brain morphology may explain the small neuroimaging effect sizes reported in polygenic psychiatric conditions. Nevertheless, latent gene brain morphology dimensions will help subgroup the rapidly expanding landscape of neuropsychiatric variants and dissect the heterogeneity of idiopathic conditions

C-band Dual-Polarization Radar Observations of a Massive Volcanic Eruption in South America

The eruption of Calbuco volcano on April 22-23, 2015 is the first volcanic eruption detected by a weather radar in South America. The detection was performed by the first domestically produced Argentinean weather radar, called RMA0 and located at Bariloche International Airport. It is a C-band Doppler dual-polarization system, manufactured by INVAP S.E. as a part of the new radar network of Argentina. The aim of this study is to present analysis of the time evolution of the structure of the volcanic plume using polarimetric observables. In order to explore the potential of this new data set for the analysis of the Calbuco volcano eruption column and dispersed ash cloud, synthetic backscattering signatures at C-band have been simulated and used to set up a threshold-based algorithm for tephra-type classification. An evaluation of lightning activity and its relationships with the volcanic particle spatial distribution and attendant polarimetric radar signatures are also discussed.Fil: Vidal, Luciano. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Nesbitt, Stephen William. University of Illinois at Urbana; Estados UnidosFil: Salio, Paola Veronica. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Centro de Investigaciones del Mar y la Atmósfera. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Centro de Investigaciones del Mar y la Atmósfera; ArgentinaFil: Farias, Camila. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; ArgentinaFil: Nicora, Maria Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Unidad de Investigación y Desarrollo Estratégico para la Defensa. Ministerio de Defensa. Unidad de Investigación y Desarrollo Estratégico para la Defensa; ArgentinaFil: Osores, María Soledad. Ministerio de Defensa. Secretaria de Planeamiento. Servicio Meteorológico Nacional; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Mereu, Luigi. Universita Di Roma; ItaliaFil: Marzano, Frank S.. Universita Di Roma; Itali

Evidence-based recruitment strategies for clinical research: Study personnels and research participants perceptions about successful methods of outreach for a U.S. Autism-Research Cohort.

INTRODUCTION: Under enrollment of participants in clinical research is costly and delays study completion to impact public health. Given that research personnel make decisions about which strategies to pursue and participants are the recipients of these efforts, we surveyed research staff (n = 52) and participants (n = 4,144) affiliated with SPARK (Simons Foundation Powering Autism for Knowledge) - the largest study of autism in the U.S. - to understand their perceptions of effective recruitment strategies. METHODS: In Study 1, research personnel were asked to report recruitment strategies that they tried for SPARK and to indicate which ones they would and would not repeat/recommend. In Study 2, SPARK participants were asked to indicate all the ways they heard about the study prior to enrollment and which one was most influential in their decisions to enroll. RESULTS: Staff rated speaking with a SPARK-study-team member (36.5%), speaking with a medical provider (19.2%), word of mouth (11.5%), and a live TV news story (11.5%) as the most successful strategies. Participants most often heard about SPARK via social media (47.0%), speaking with a medical provider (23.1%), and an online search (20.1%). Research personnels and participants views on effective recruitment strategies often differed, with the exception of speaking with a medical provider. CONCLUSION: Results suggest that a combination of strategies is likely to be most effective in reaching diverse audiences. Findings have implications for the selection of strategies that meet a studys specific needs, as well as recruitment-strategy combinations that may enhance the influence of outreach efforts

Cuaderno de nivelación de competencias matemáticas ciclo VI : cuaderno de nivelación de competencias matemáticas de primer grado de educación secundaria para los modelos de servicio educativo en el ámbito rural

Este cuaderno está formado por ocho unidades, cada una con tres niveles de desafíos. Aquí los estudiantes podrán jugar con números, manipular objetos, descubrir propiedades e intercambiar ideas y procedimientos