Facilitating online discussion, tutoring and moderating skills in clinical psychology lecturers

The inclusion of online approaches in clinical psychology training has necessitated an examination of the skills required by trainers. This paper describes the development of a short tutorial to promote online discussion tutoring and moderation skills in clinical psychology lecturers

Improving institutional memory on challenges and methods for estimation of pig herd antimicrobial exposure based on data from the Danish Veterinary Medicines Statistics Program (VetStat)

With the increasing occurrence of antimicrobial resistance, more attention has been directed towards surveillance of both human and veterinary antimicrobial use. Since the early 2000s, several research papers on Danish pig antimicrobial usage have been published, based on data from the Danish Veterinary Medicines Statistics Program (VetStat). VetStat was established in 2000, as a national database containing detailed information on purchases of veterinary medicine. This paper presents a critical set of challenges originating from static system features, which researchers must address when estimating antimicrobial exposure in Danish pig herds. Most challenges presented are followed by at least one robust solution. A set of challenges requiring awareness from the researcher, but for which no immediate solution was available, were also presented. The selection of challenges and solutions was based on a consensus by a cross-institutional group of researchers working in projects using VetStat data. No quantitative data quality evaluations were performed, as the frequency of errors and inconsistencies in a dataset will vary, depending on the period covered in the data. Instead, this paper focuses on clarifying how VetStat data may be translated to an estimation of the antimicrobial exposure at herd level, by suggesting uniform methods of extracting and editing data, in order to obtain reliable and comparable estimates on pig antimicrobial consumption for research purposes.Comment: 25 pages, including two Appendices (pages not numbered). Title page, including abstract, is on page 1. Body of text, including references, abbreviation list and disclaimers for conflict of interest and funding, are on pages 2-18. Two figures embedded in the text on pages 3 and 5. Appendix 1 starts on page 19, and Appendix 2 on page 2

Global Fluoroquinolone Resistance Epidemiology and Implictions for Clinical Use

This paper on the fluoroquinolone resistance epidemiology stratifies the data according to the different prescription patterns by either primary or tertiary caregivers and by indication. Global surveillance studies demonstrate that fluoroquinolone resistance rates increased in the past years in almost all bacterial species except S. pneumoniae and H. influenzae, causing community-acquired respiratory tract infections. However, 10 to 30% of these isolates harbored first-step mutations conferring low level fluoroquinolone resistance. Fluoroquinolone resistance increased in Enterobacteriaceae causing community acquired or healthcare associated urinary tract infections and intraabdominal infections, exceeding 50% in some parts of the world, particularly in Asia. One to two-thirds of Enterobacteriaceae producing extended spectrum -lactamases were fluoroquinolone resistant too. Furthermore, fluoroquinolones select for methicillin resistance in Staphylococci. Neisseria gonorrhoeae acquired fluoroquinolone resistance rapidly; actual resistance rates are highly variable and can be as high as almost 100%, particularly in Asia, whereas resistance rates in Europe and North America range from 30% in established sexual networks. In general, the continued increase in fluoroquinolone resistance affects patient management and necessitates changes in some guidelines, for example, treatment of urinary tract, intra-abdominal, skin and skin structure infections, and traveller’s diarrhea, or even precludes the use in indications like sexually transmitted diseases and enteric fever

Zur (Un-)Möglichkeit von Widerstand gegen Unterdrückung und Herrschaft

Das Theater der Unterdrückten bewegt sich im Spannungsfeld eigener Ansprüche und gesellschaftlicher Rahmenbedingungen. Die vorliegende Arbeit beschäftigt sich mit der Frage, ob das Theater der Unterdrückten durch das Schaffen emanzipatorischer Umgangsformen, Lebensweisen und Lernarten zur Veränderung gesellschaftlicher Rahmenbedingungen beiträgt oder aber Dominanzen reproduziert und somit kontraproduktiv wirkt. Eine kritische Überprüfung dieser sich als herrschaftskritisch und antiautoritär verstehenden Theaterform erfolgt mittels eines Vergleichs mit Ansätzen herrschaftsfreier Bildung. Da sich sowohl das Theater der Unterdrückten als auch herrschaftsfreie Bildungsansätze hauptsächlich auf einen repressiven Machtbegriff stützen, wird der Vergleich in einem weiteren Schritt mit poststrukturalistischen Ansätzen abgeglichen.The Theatre of the Oppressed prevails within an area of tension between its own demands and the basic conditions of society. The paper at hand deals with the question of whether the Theatre of the Oppressed contributes to societal conditions through the creation of emancipatory forms, ways of living and of learning, or reproduces dominances and thus works counterproductively. A critical assessment of this form of theatre, which understands itself to be critical of domination and anti-authoritarian, is to be carried out by means of a comparison with nonhierarchical education. Given that both the Theatre of the Oppressed and nonhierarchical educational approaches primarily draw upon a repressive concept of power, poststructuralist approaches are added to the comparison in a further step

Wissenschaftliche Karrierewege von Medizinerinnen und Strategien zu ihrer Förderung

'Der Beitrag beschreibt und analysiert die vertikale geschlechtsspezifische Segregation in wissenschaftlichen Einrichtungen in Deutschland unter besonderer Berücksichtigung der medizinischen Fächer (vertikale Segregation: mit aufsteigender Qualifikations- und Gehaltsstufe sinkt der Frauenanteil in dem Fach). Ausgehend von den wichtigsten Erklärungsansätzen werden beispielhaft bestehende Strukturen und Maßnahmen auf nationaler und europäischer Ebene vorgestellt, die dem erklärten Ziel dienen, die geschlechtergerechte Teilhabe in Forschung und Lehre nachhaltig voranzutreiben.' (Autorenreferat)'The article describes and analyses the sex-specific horizontal and vertical segregation in German academia and research institutions in special view of the medical sciences. Starting from the most important aspects of explanation, best-practice-examples of structures and measures on national and European level are pointed out. All of them having the same target: coming up to a just participation of women and men in science.' (author's abstract)

Landbrugets Forsikringsvæsen i Danmark.

Landbrugets Forsikringsvæsen i Danmark

Determination of the Primary Molecular Target of 1,2,4-Triazole-Ciprofloxacin Hybrids

We have synthesized and examined the antibacterial activity, toxicity and affinity towards bacterial type II topoisomerases of a series of 1,2,4-triazole-ciprofloxacin hybrids. A number of these compounds displayed enhanced activity against Gram-positive and Gram-negative bacteria when compared to ciprofloxacin. The toxic concentrations of the obtained derivatives, evaluated on HEK-293 cells using MTT assay, were much higher than concentrations required to produce antibacterial effect. Finally, the results of enzymatic studies showed that the analyzed compounds demonstrated other preferences as regards primary and secondary molecular targets than ciprofloxacin.This research was supported by the Ministry of Science and Higher Education under Iuventus Plus grant No. IP2014 037473. Tomasz Plech is a recipient of the Fellowship for Young Researchers with Outstanding Scientific Achievements from the Medical University of Lublin (Lublin, Poland)