Analysis of 5G-TSN Integration to Support Industry 4.0

Time Sensitive Networking (TSN) is becoming the standard Ethernet-based technology for converged networks of Industry 4.0 due to its capacity to support deterministic latency requirements. However, it cannot provide the required flexibility to support mobile industrial applications required for the factories of the future. This could be enabled through the integration of wireless technologies in factories, and in particular of 5G and Beyond networks since they have been designed to support ultra-reliable and low-latency communications. This has triggered significant interest to integrate 5G and TSN networks, and first frameworks for such integration have been defined. However, the work is at early stages and the solutions to effectively integrate the two networks so that 5G can support TSN QoS levels are yet to be designed. This paper discusses current research and standardization work on 5G-TSN integration, and quantifies for a closed loop control application the 5GS bridge delay. The paper uses an example based on 5G-ACIA [1] to discuss open technical and research challenges to effectively integrate 5G and TS

Caracterització dels vins monovarietals de sumoll de la DO Tarragona

Aquest article presenta els resultats obtinguts d'estudis de caracterització fenòlica realitzats per l'Estació de Viticultura i Enologia (EVE) de Reus (INCAVI), amb el suport i la col·laboració del Consell Rector de la DO Tarragona i de la Cooperativa de Rodonyà, sobre la varietat sumoll plantada al terme municipal de Rodonyà. Els resultats obtinguts, amb classificacions dels grups estudiats mitjançant funcions discriminants, permeten avançar una clara caracterització d'aquesta varietat respecte a d'altres vins elaborats dins la seva mateixa àrea geogràfica.Este artículo presenta los resultados obtenidos de estudios de caracterización fenólica realizados por la Estación de Viticultura y Enología (EVE) de Reus (INCAVI), con el soporte y la colaboración del Consejo Rector de la DO Tarragona y de la Cooperativa Agrícola de Rodonyà, sobre la variedad sumoll plantada en el término municipal de Rodonyà. Los resultados obtenidos, con clasificaciones de los grupos estudiados mediante funciones discriminantes, permiten avanzar una clara caracterización de esta variedad respecto a otros vinos elaborados dentro de su misma área geográfica

Interference between variants of peach latent mosaic viroid reveals novel features of its fitness landscape: implications for detection

[EN] Natural populations of peach latent mosaic viroid (PLMVd) are complex mixtures of variants. During routine testing, TaqMan rtRT-PCR and RNA gel-blot hybridization produced discordant results with some PLMVd isolates. Analysis of the corresponding populations showed that they were exclusively composed of variants (of class II) with a structural domain different from that of the reference and many other variants (of class I) targeted by the TaqMan rtRT-PCR probe. Bioassays in peach revealed that a representative PLMVd variant of class II replicated without symptoms, generated a progeny with low nucleotide diversity, and, intriguingly, outcompeted a representative symptomatic variant of class I when co-inoculated in equimolecular amounts. A number of informative positions associated with the higher fitness of variants of class II have been identified, and novel sets of primers and probes for universal or specific TaqMan rtRT-PCR detection of PLMVd variants have been designed and tested.We thank A. Ahuir for excellent technical assistance and Dr. Francesco Di Serio for suggestions. This work was supported by grant BFU2014-56812-P (to R.F.) from Ministerio de Economia y Competitividad (MINECO) of Spain. P.S. was the recipient of a postdoctoral contract from MINECO and E. Bertolini of an INIA-CCA2011-2016 contract also from MINECO.Serra Alfonso, P.; Bertolini, E.; Martinez, MC.; Cambra, M.; Flores Pedauye, R. (2017). Interference between variants of peach latent mosaic viroid reveals novel features of its fitness landscape: implications for detection. Scientific Reports. 7. https://doi.org/10.1038/srep42825S7Diener, T. O. Discovering viroids - a personal perspective. Nat. Rev. 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Assessment of the corneal collagen organization after chemical burn using second harmonic generation microscopy

The organization of the corneal stoma is modified due to different factors, including pathology, surgery or external damage. Here the changes in the organization of the corneal collagen fibers during natural healing after chemical burn are investigated using second harmonic generation (SHG) imaging. Moreover, the structure tensor (ST) was used as an objective tool for morphological analyses at different time points after burn (up to 6 months). Unlike control corneas that showed a regular distribution, the collagen pattern at 1 month of burn presented a non-organized arrangement. SHG signal levels noticeably decreased and individual fibers were hardly visible. Over time, the healing process led to a progressive re-organization of the fibers that could be quantified through the ST. At 6 months, the stroma distribution reached values similar to those of control eyes and a dominant direction of the fibers re-appeared. The present results show that SHG microscopy imaging combined with the ST method is able to objectively monitor the temporal regeneration of the corneal organization after chemical burn. Future implementations of this approach into clinically adapted devices would help to diagnose and quantify corneal changes, not only due to chemical damages, but also as a result of disease or surgical procedures

A genome-wide 20 K citrus microarray for gene expression analysis

<p>Abstract</p> <p>Background</p> <p>Understanding of genetic elements that contribute to key aspects of citrus biology will impact future improvements in this economically important crop. Global gene expression analysis demands microarray platforms with a high genome coverage. In the last years, genome-wide EST collections have been generated in citrus, opening the possibility to create new tools for functional genomics in this crop plant.</p> <p>Results</p> <p>We have designed and constructed a publicly available genome-wide cDNA microarray that include 21,081 putative unigenes of citrus. As a functional companion to the microarray, a web-browsable database <abbrgrp><abbr bid="B1">1</abbr></abbrgrp> was created and populated with information about the unigenes represented in the microarray, including cDNA libraries, isolated clones, raw and processed nucleotide and protein sequences, and results of all the structural and functional annotation of the unigenes, like general description, BLAST hits, putative Arabidopsis orthologs, microsatellites, putative SNPs, GO classification and PFAM domains. We have performed a Gene Ontology comparison with the full set of Arabidopsis proteins to estimate the genome coverage of the microarray. We have also performed microarray hybridizations to check its usability.</p> <p>Conclusion</p> <p>This new cDNA microarray replaces the first 7K microarray generated two years ago and allows gene expression analysis at a more global scale. We have followed a rational design to minimize cross-hybridization while maintaining its utility for different citrus species. Furthermore, we also provide access to a website with full structural and functional annotation of the unigenes represented in the microarray, along with the ability to use this site to directly perform gene expression analysis using standard tools at different publicly available servers. Furthermore, we show how this microarray offers a good representation of the citrus genome and present the usefulness of this genomic tool for global studies in citrus by using it to catalogue genes expressed in citrus globular embryos.</p

Hepatic protein tyrosine phosphatase 1B (PTP1B) deficiency protects against obesity-induced endothelial dysfunction

Acknowledgments This work was supported by a Diabetes UK project grant to Dr M. Delibegović (BDARD08/0003597), Tenovus Scotland grant to Dr. M. Delibegovic and Dr. A. Agouni and travel grants from the Physiological Society and Company of Biologists to Dr. A. Agouni. Dr Delibegovic is also funded by an RCUK Fellowship, British Heart Foundation, EFSD/Lilly diabetes programme grant and the Royal Society. Dr Agouni is funded by the Royal Society and the Physiological Society. This work is supported by the INSERM and CHU of Angers. The authors are thankful to the functional imaging center of Angers (CIFAB) for the use of echocardiography.Peer reviewedPostprin

AGROTECH09: building agricultural robots with lego mindstorm. A multidisciplinary and multicultural approach

This activity has been designed in the context of an innovation project devoted to the coordination on mathematical, physical, and engineering contents for a transversal path on mechatronics, automated control and information and communication technologies (from now onwards AGROMECATIC) at agricultural engineering studies in the Technical University of Madrid. One of the main tasks has consisted on setting up a new subject, robotics in agriculture (equivalent to 7 ECTS), which is used as a platform to test the abilities of the students to apply various aspects of the knowledge gathered along the previous 4 years on agricultural engineering, with special emphasis on. The students are demanded to build a variety of basic mechanisms into an autonomous vehicle capable of performing user defined general and specific agricultural tasks (such as selective harvest, transport, loading and unloading of product). The robot is programmed using object oriented language (LEJOS, JAVA for LEGO) and has to cover a variety of behaviors: navigation, exploration, and previous defined agricultural tasks. As a mean to test the skills developed by the students and to reinforce the multidisciplinary nature of AGROMECATICS, a European contest: AGROTECH09 has been settled, which is co-organized by BEST (Board of European Students of Technology). The activity will take place between the 11 th and 14 th of May at ETSI Agrónomos and recognizes up to 2 ECTS of individual dedication. 40 students from 16 countries with large variability of backgrounds: computers science, agronomy, engineering, physics, tele-communication will work jointly to solve a challenge which will be public on the 11 th of May with all materials being provided by the organization

Atmospheric deposition fluxes of aluminium, iron and trace metals in a coastal station on the NW-Alboran Sea, (W-Mediterranean)

El estudio se ha realizado en el marco del Proyecto del Plan Nacional con ref. CTM12-37598-C02The atmospheric deposition over the whole Mediterranean is poorly constrained and hinders a clear assessment of the extent to which atmospheric elements of various anthropogenic and natural origins affect its biogeochemistry. Available data show poor spatial representation, as most of the deposition data refer to the northwestern zone. The Alboran Sea, in particular, is a very interesting case study as regards the atmospheric input because the atmospheric chemistry is dominated by antagonistic influences of natural (mainly from the Sahara) and human activity due to the relative proximity of land-based sources and densely populated shores. The biogeochemical impact of desert dust also remains a matter of discussion regarding its contribution for different major and minor elements to terrestrial and marine systems and especially its potential fertilizing role by supplying micronutrients as iron. Atmospheric fluxes of various trace metals were measured in order to evaluate the presence of these elements in their differently bio-available forms, contents in the soluble and non-soluble fractions were determined. Sampling presented for this study was performed in Malaga (southeast of Spain, 36° 43′ 40″ N; 4° 28′ 8″ W) in an open bulk deposition collector placed 10 m above the ground. The Hybrid Single-Particle Lagrangian Integrated Trajectory (HYSPLIT) model was used to calculate the backward trajectories of air masses reaching the study region.Universidad de Málaga. Campus de Excelencia Internacional Andalucía Tech

Ecological model of factors associated with dating violence

La violencia de género en parejas adolescentes (VPA) hace referencia a comportamientos abusivos reiterados que un chico adolescente ejerce contra una chica con la que mantiene o ha mantenido una relación sentimental con la intención de ejercer dominio y control sobre la chica y la relación. Este comportamiento se clasifica en cuatro tipos de agresiones: física, psicológica, sexual y económica. Recientes investigaciones hacen visible una realidad que afecta a millones de mujeres en todo el mundo y ayudan a comprender los mecanismos de la violencia de pareja. Uno de los hallazgos más importantes de esta investigación ha señalado que el origen de la violencia de género se encuentra en las primeras relaciones de pareja durante adolescencia. El modelo ecológico de los factores asociados con la violencia de género en parejas adolescentes ofrece un marco teórico explicativo adecuado para la investigación, la intervención y la prevención en este campo. La implicación del profesorado, padres y madres en los programas de prevención e intervención multidisciplinar en todo el proceso de prevención ayudarían a los/as adolescentes que comienzan una relación de pareja violenta a salir de esta situación. Por otra parte, una mayor sensibilidad de los medios de comunicación hacia esta realidad fomentaría un cambio hacia unas relaciones más igualitarias y menos discriminatorias en los roles y creencias que se establecen entre chicos y chicas cuando comienzan sus primeras relaciones de pareja.Gender violence in teen dating (VPA henceforth) refers to repeated abusive behavior exerts a teenage boy against a girl that maintains or has maintained a relationship with the intention to exercise dominion and control over the girl and the relationship. This behavior is classified into four types of agression: physical, psychological, sexual and economic. Recent research makes visible a reality that affects millions of women worldwide and helps understand the mechanisms of partner violence. One of the most important findings of this research has indicated that the source of this violence comes from the first couple relationship during adolescence. The dynamics of violent relationship established between pairs of young teens seem to have explanatory multi-causal origins. The ecological model of factors associated with domestic violence in teen dating provides an adequate explanatory framework for research work, intervention and prevention in this field. The involvement of teachers and parents in prevention programs and the development of multidisciplinary intervention programs throughout the process to help prevent adolescents who begin a relationship with a violent partner from a different background. Moreover, an increased sensitivity of the media towards this reality would encourage a shift towards more egalitarian and less discriminatory behaviors in roles and beliefs that exist between boys and girls when they start their first relationship.Departamento de Educación y Psicología SocialVersión del edito