Instituto de Neurociencias de Alicante

RediUMH (Universidad Miguel Hernández)
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    Crear pese a todo: la producción artística como motor crítico

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    Ante un presente caracterizado por crisis permanentes, una desesperanza difícilmente combatible y un individualismo rampante, el arte puede funcionar como una herramienta para activar la mirada crítica y construir alternativas posibles. El artículo explora la capacidad de activación simbólica y emocional del arte, de restauración de las comunidades e impulso de cambios sociales. Partiendo desde los años 60, se expone como se intensificó la conexión entre arte y política y se exploran problemáticas concretas sobre las que se ha trabajado, como la emergencia climática con el colectivo Basurama, con una actividad centrada en la crítica al sobreconsumo, y Agnes Denes, artista que ha trabajado directamente sobre el medio natural restaurando espacios. Por otro lado, se exploran propuestas feministas con Regina José Galindo, que emplea su cuerpo en performances como una herramienta para denunciar la violencia ejercida sobre las mujeres, y con Guerrilla Girls, que usando tácticas publicitarias y la gráfica han cuestionado cómo en las instituciones culturales permean también los patrones de desigualdad. Son prácticas que interpelan al espectador y que además reivindican el arte como un espacio de resistencia, reparación y de generación de nuevas posibilidades y formas de vida que sean más sostenibles e igualitariasIn the face of a present characterized by permanent crises, a hopelessness that is difficult to combat and a rampant individualism, art can function as a tool to activate the critical gaze and build possible alternatives. The article explores the capacity of art to activate symbolically and emotionally, to restore communities and to promote social change. Starting from the 60s, it shows how the connection between art and politics intensified and explores specific problems on which work has been done, such as the climate emergency with the Basurama collective, with an activity focused on the criticism of overconsumption, and Agnes Denes, an artist who has worked directly on the natural environment restoring spaces. On the other hand, feminist proposals are explored with Regina José Galindo, who uses her body in performances as a tool to denounce the violence exerted on women, or Guerrilla Girls, who using advertising tactics and graphics have questioned how patterns of inequality also permeate cultural institutions. They are practices that challenge the viewer and that also vindicate art as a space of resistance, repair and the generation of new possibilities and ways of life that are more sustainable and egalitaria

    Análisis de los 10 años de evolución de las Aulas Respira, un proyecto integral de educación para pacientes respiratorios

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    Introducción: La educación para pacientes con enfermedades respiratorias crónicas es un pilar esencial del manejo integral, que mediante programas estructurados como las Aulas Respira promueve el autocuidado, mejora la adherencia, la calidad de vida y reduce la carga asistencial, integrando enfoques presenciales y digitales con impacto positivo en la salud individual y pública. Material y métodos: Se realizó un estudio retrospectivo, transversal y descriptivo entre 2010 y 2020 para evaluar cualitativamente las Aulas Respira como proyecto de educación compartida en 85 hospitales españoles. Estas aulas, impulsadas por SEPAR, consistieron en encuentros entre especialistas, pacientes y cuidadores, centrados en el manejo y prevención de enfermedades respiratorias. Se emplearon materiales didácticos estructurados (guías, presentaciones, fichas y vídeos) y encuestas anónimas para valorar satisfacción y participación. La información se recopiló mediante cuestionarios a profesionales y evaluaciones de pacientes, analizándose con métodos estadísticos descriptivos e inferenciales (Chi-cuadrado, Fisher, Pearson y Spearman). Resultados: Durante el periodo de estudio, un total de 85 hospitales en España se incorporaron a la Red de Aulas Respira, organizando 18 unidades formativas de carácter nacional, con un crecimiento sostenido hasta alcanzar 140 aulas en 2019 y casi 6.000 participantes anuales, acumulando 55.540 pacientes en toda la serie histórica. Los neumólogos fueron los principales impulsores de estas actividades (67 %), seguidos de enfermería (19 %), fisioterapeutas (10 %) y otros profesionales, con predominio de la franja de edad de 40 a 54 años (47 %) y una participación equilibrada por género (51 % hombres y 49 % mujeres). La implicación profesional fue elevada, con un 86 % participando directamente en la organización y ejecución de las aulas, y casi la mitad coordinando entre dos y cinco sesiones; además, se observó correlación significativa entre edad y número de aulas organizadas (r=0,65, p<0.001). La valoración de los materiales y la utilidad percibida por los profesionales fue muy positiva. La mayoría de las aulas contó con grupos reducidos de participantes, predominando entre 20 y 30 asistentes, y la participación activa de pacientes y cuidadores fue altamente valorada. Las principales dificultades señaladas fueron la falta de apoyo institucional y escasa implicación de algunos jefes de servicio. La distribución geográfica mostró concentración en Cataluña y Comunidad Valenciana, seguida de Madrid, con menor participación en otras comunidades. Los pacientes asistentes fueron mayoritariamente personas mayores (media 71 ± 16 años), con predominio de hombres (55 %) y enfermedades como apnea obstructiva del sueño (64 %), EPOC (18 %), enfermedades neuromusculares (9 %) y asma (9 %). La valoración global de los pacientes fue excelente, con el 91 % considerando la información recibida muy útil y la totalidad recibiendo material educativo complementario, altamente valorado. Además, el 84 % destacó la interacción social y emocional, y la recomendación de asistencia fue elevada, evidenciando un impacto positivo tanto en la satisfacción como en la percepción de participación, con diferencias significativas a favor de los pacientes frente a los profesionales. Conclusiones: Las Aulas Respira, con organizadores mayoritariamente de edades medias y algunos coordinadores muy fieles, reúnen 25-40 pacientes por sesión. La participación ha crecido con el tiempo, pese al impacto de la pandemia, y los pacientes valoran la experiencia y utilidad como excelente, cumpliendo los objetivos de autocuidado, educación sanitaria e interacción con los profesionales, aunque persisten desafíos como la captación de pacientes y barreras burocráticas.Introduction: Education for patients with chronic respiratory diseases is a key component of comprehensive management. Structured programs such as Aulas Respira promote self-care, improve treatment adherence and quality of life, and reduce healthcare burden, integrating in-person and digital approaches with a positive impact on individual and public health. Materials and Methods: A retrospective, cross-sectional, descriptive study was conducted between 2010 and 2020 to qualitatively evaluate Aulas Respira as a shared education project in 85 Spanish hospitals. These sessions, promoted by SEPAR, involved meetings between specialists, patients, and caregivers, focusing on the management and prevention of respiratory diseases. Structured educational materials (guides, presentations, handouts, and videos) and anonymous surveys were used to assess satisfaction and participation. Data were collected through professional questionnaires and patient evaluations, and analyzed using descriptive and inferential statistics (Chi-square, Fisher, Pearson, and Spearman). Results: During the study period, 85 hospitals in Spain joined the Aulas Respira Network, organizing 18 national training units, with sustained growth reaching 140 sessions in 2019 and nearly 6,000 annual participants, totaling 55,540 patients historically. Pulmonologists were the main drivers (67 %), followed by nurses (19 %), physiotherapists (10 %), and other professionals, predominantly aged 40–54 years (47 %), with balanced gender participation (51 % male, 49 % female). Professional involvement was high, with 86 % participating directly in session organization and execution, nearly half coordinating 2–5 sessions, and a significant correlation between age and number of sessions organized (r=0.65, p<0.001). Materials and perceived usefulness were rated very positively. Most sessions had small groups (20–30 participants), with highly valued active participation from patients and caregivers. Main challenges included lack of institutional support and limited engagement from some department heads. Geographically, sessions were concentrated in Catalonia and the Valencian Community, followed by Madrid, with lower participation elsewhere. Attending patients were mostly older adults (mean 71 ± 16 years), predominantly male (55 %), with conditions such as obstructive sleep apnea (64 %), COPD (18 %), neuromuscular diseases (9 %), and asthma (9 %). Overall patient evaluation was outstanding, with 91 % rating the information as very useful, all receiving complementary educational material highly valued. Additionally, 84 % highlighted social and emotional interaction, and recommendation rates were high, showing a positive impact on satisfaction and perceived participation, with significant differences favoring patients over professionals. Conclusions: Aulas Respira, mainly organized by middle-aged professionals with some highly committed coordinators, host 25–40 patients per session. Participation has increased over time despite the pandemic’s impact, and patients rate the experience and usefulness as excellent, fulfilling objectives of self-care, health education, and interaction with professionals, although challenges remain in patient recruitment and bureaucratic barriers

    Los usos de territorio en la Comunidad Valenciana y España: la agricultura

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    La adaptación de diálogos y la construcción de la personalidad en el doblaje de comedia animada. Un análisis comparativo entre la versión original, el español peninsular y el español latino en películas de DreamWorks

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    El presente Trabajo de Fin de Grado analiza cómo la adaptación de los diálogos y la interpretación vocal en el doblaje influyen en la construcción de la personalidad de los personajes dentro de la animación de comedia. El estudio se desarrolla mediante un análisis comparativo entre la versión original en inglés, el doblaje al español peninsular y el doblaje al español latinoamericano en tres películas del estudio DreamWorks: Shrek (2001), Madagascar (2005) y Vecinos invasores (2006). Los resultados muestran que el doblaje no constituye únicamente un proceso de traducción del guion original, sino una reinterpretación cultural y vocal que puede modificar la percepción del personaje. Así, se confirma que las decisiones lingüísticas y la actuación vocal influyen directamente en la identidad narrativa, generando versiones del personaje ligeramente distintas según el contexto lingüístico y cultural.This Final Degree Project examines how dialogue adaptation and vocal performance in dubbing influence character personality construction in animated comedy films. The study presents a comparative analysis between the original English version, Peninsular Spanish dubbing and Latin American Spanish dubbing in three DreamWorks productions: Shrek (2001), Madagascar (2005) and Over the Hedge (2006). The findings show that dubbing goes beyond translating the original script, functioning instead as a cultural and vocal reinterpretation capable of modifying character perception. Consequently, linguistic decisions and vocal performance directly influence narrative identity, generating slightly different character constructions depending on the linguistic and cultural version

    Derecho civil y nuevas tecnologías: blockchain, smart contracts y contrato de préstamo.

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    Tras la crisis económica de 2008, muchos son los cambios que se han acontecido en el mundo de las finanzas y el derecho, trayendo consigo una serie de tecnologías tan revolucionarias como son las blockchains y los smart contracts. a lo largo del presente trabajo analizaremos ambas figuras, así como la aplicación de las mismas al ámbito de los préstamos, denominado crowdlending, examinando cómo las instituciones han adaptado sus reglamentos, actualizándose en la materia para lograr la protección de las partes implicadas a la hora de contratar

    Application of quinoa oil emulsions in fresh goat cheese: effects on lipid profile, technological properties and microstructure

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    This study investigates the use of quinoa oil emulsion as a novel plant-based ingredient to improve the nutritional quality of fresh goat cheese. Quinoa oil emulsions (3 and 6 g/L) were characterized and incorporated in fresh cheese. The effects on nutritional composition, lipid oxidation, microbiological and sensory attributes, texture and microstructure were evaluated. The addition of quinoa oil emulsion to milk before the cheesemaking improved the lipid profile of the cheeses by increasing the content of linoleic and a-linolenic acids. Overall, the microstructure of the fortified cheeses looked like the typical protein-lipid network of cheese. Additionally, the addition of quinoa oil did not increase oxidative deterioration, and microbial growth was unaffected. Textural changes were minor and unlikely to impair consumer perception as sensory evaluation confirmed that fortified cheeses were well accepted, with overall acceptance similar to that for traditional formulation

    Diseño y automatización de una máquina para el montaje de opérculos en tapones mediante un PLC

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    El objetivo del trabajo fin de grado consiste en el diseño tanto mecánico como eléctrico y en la automatización de una máquina destinada a realizar de forma cíclica y sin intervención humana el montaje automatizado de una pieza industrial. En concreto, se trata de una estación automática que se encarga de ensamblar un opérculo sobre un tapón, aplicando previamente una dosis controlada de adhesivo termofusible.The objective of the final degree project is the mechanical and electrical design, as well as the automation, of a machine intended to cyclically and autonomously carry out the automated assembly of an industrial component. Specifically, it involves an automatic station responsible for assembling an operculum onto a cap, previously applying a controlled dose of hot-melt adhesive

    Use of DMU e-Parasitology in a West African university.

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    Following the devastating effects of the 2013-16 ebola outbreak on the Sierra Leonean public health system, De Montfort University (DMU, UK) is leading a project to build the teaching and research capabilities of medical parasitology at the University of Makeni (UniMak, Sierra Leone). A DMU researcher visited UniMak for two weeks in April 2019 and provided a voluntary short training course (theoretical and practical) in basic parasitology, using our novel web-based resource DMU e-Parasitology® (http://parasitology.dmu.ac.uk/index.htm), which is little taught in their programmes. Following this training, UniMak’s academics offered a voluntary practical to study the presence of coccidian human parasites in farm pig stool samples to final year students enrolled in the degree of ‘Public Health: Medical Laboratory Sciences’. Nine of the eighteen students that attended the practical provided feedback: 88.9% (22.2% agreed, 66.7% strongly agreed) indicated that the videos displaying how to perform the Kinyoun stain facilitated their learning; and only 11.1% indicated that the web-based resources did not help them to perform the Kinyoun stain. Our results would indicate that the DMU e-Parasitology® is an appropriate resource to introduce and facilitate the teaching of emerging and opportunistic parasitic diseases in a low-income university

    Bridging clinical and environmental reservoirs: antimicrobial resistance in the emerging pathogen Shewanella algae

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    The emergence of antimicrobial resistance in environmental bacteriathreatens therapeutic efficacy in clinical settings. Shewanella algae, historically regarded as a marine saprophyte, is increasingly recognized as an emerging opportunisticpathogen. In this study, we analyzed 86 S. algae isolates from Spain (19 clinical and 67environmental) and integrated them with 178 publicly available genomes to exploreantimicrobial susceptibility patterns and genomic diversity. Penicillins and fosfomycinconsistently showed poor activity, whereas piperacillin/tazobactam, third- and fourth-generation cephalosporins, aminoglycosides, ciprofloxacin, trimethoprim–sulfamethoxazole and several novel β-lactam–inhibitor combinations exhibited low MIC distributions.Recently introduced agents, including ceftazidime/avibactam, ceftolozane/tazobactam,and cefiderocol, also demonstrated strong in vitro activity. Carbapenems displayedan unusual intraclass pattern, with imipenem showing markedly higher MICs thanmeropenem and ertapenem. When interpreted using CLSI’s “Other Non-Enterobacterales” criteria, clinical and environmental isolates exhibited largely overlapping susceptibility profiles, highlighting the potential role of environmental strains as reservoirsof resistance-related traits. Genomic profiling revealed a conserved intrinsic resistome(OXA-type β-lactamases, qnrA variants, ugd, and efflux regulators) together withhorizontally acquired determinants. A 29 kb genomic island carrying multiple resistance genes was identified in a clinical isolate, with homologous structures detectedin Vibrio and Proteus, suggesting interspecies transfer. Furthermore, plasmids harboringclass 1 integrons (mobile integrons) were widespread, shared with Enterobacterales andVibrionaceae across clinical and environmental settings. Overall, these findings highlightS. algae as both a clinically relevant pathogen and a reservoir of mobile AMR determinants and underscore the urgent need for species-specific antimicrobial susceptibilityinterpretive criteria to improve clinical decision-making for this emerging pathogen

    Stressful Life Events and Suicide: Examining the Role of Socio-Emotional Strengths

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    Stressful Life Events (SLEs) during adolescence are linked to a higher risk of suicidal behavior and nonsuicidal self-injury (NSSI). However, the specific impact of each type of SLE has been under-researched. Socio-emotional strengths, including belief in self, belief in others, Emotional Competence, and Engaged Living, are key promotive factors for mental health and may mitigate the impact of SLEs on suicidal behavior and NSSI. This study aims to systematically explore the potential indirect effects of socio-emotional strengths in the relationship between SLEs over the past year, grouped by functional areas, and indicators of suicidal behavior and NSSI. Method: 2,283 adolescents aged 10 to 19 years (M = 13.99; SD = 1.40) participated in the study, completing scales on SLEs, socio-emotional strengths, and suicidal behavior and NSSI reported over the past year. Results: From the sample, 13.4% of participants reported suicidal desire, 10.5% suicidal ideation, 6.6% NSSI, 5.5% suicide planning, and 2.2% suicide attempts. In the main analyses, Suicidal Behavior (Death Wishes, Ideation, Plans, Attempts) and NSSI were modeled separately. Belief-in-Self and Engaged Living were negatively associated with both outcomes, while Emotional Competence showed a small positive link with suicidal behavior. Peer and Health-Related SLEs had direct effects on both suicidal behavior and NSSI. Indirect effects emerged through Belief-in-Self and Engaged Living. Conclusions: Socio-emotional strengths may play a protective and mediating role in the association between SLEs and Suicidal Behaviors and NSSI in adolescents. Findings highlight the relevance of targeting these strengths in school-based prevention efforts

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