628 research outputs found

    Le financement du réseau collégial québécois : un bref état des lieux

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    Comprend des références bibliographiques.Ce rapport de recherche a été réalisé pour le compte de la Fédération étudiante collégiale du Québec (FECQ)

    Le financement du réseau collégial québécois : quelques pistes de solution

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    Comprend des références bibliographiques.Ce rapport de recherche a été réalisé pour le compte de la Fédération étudiante collégiale du Québec (FECQ)

    La participation des peuples autochtones Ă  l’évaluation d’impact au Canada : au-delĂ  du consentement, une conception de l’autoritĂ© dĂ©cisionnelle

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    Ce mĂ©moire vise Ă  mieux comprendre les dĂ©bats politiques concernant la participation des peuples autochtones Ă  la prise de dĂ©cision en matiĂšre de dĂ©veloppement du territoire et des ressources dans le contexte de l’évaluation d’impact au Canada. Si l’évaluation d’impact est perçue comme un mĂ©canisme au sein duquel se matĂ©rialisent les droits autochtones (dont l’obligation de consulter de la Couronne), les principaux acteurs de ces processus (gouvernement fĂ©dĂ©ral, promoteurs des projets et groupes autochtones) ne semblent pas s’entendre sur la signification et la portĂ©e des normes en matiĂšre de participation autochtone, en particulier sur le consentement prĂ©alable, libre et Ă©clairĂ© (CPLE). Par une analyse du discours de ces intervenants dans le cadre des travaux parlementaires menant Ă  l’adoption de la Loi sur l’évaluation d’impact (2019), cette recherche rĂ©vĂšle trois conceptions principales de la place des Autochtones dans les processus de prise de dĂ©cision de l’évaluation d’impact : procĂ©durale, partenariale et fondĂ©e sur l’autodĂ©termination. Ce mĂ©moire met aussi en Ă©vidence d’importantes diffĂ©rences en ce qui concerne les attentes face au modĂšle de participation et plus spĂ©cifiquement sur l’interprĂ©tation du CPLE. Ces diffĂ©rences reposent en grande partie sur la façon dont ceux-ci conçoivent l’autoritĂ© dĂ©cisionnelle en matiĂšre de gouvernance territoriale au Canada. Pour les intervenants gouvernementaux et autochtones, les conceptions en matiĂšre de participation et d’autoritĂ© dĂ©cisionnelle s’appuient sur des fondements juridiques. En revanche, pour l’industrie, la justification de la participation des Autochtones est davantage de nature Ă©conomique et liĂ©e Ă  son impact sur l’approbation des projets.This thesis aims to better understand the political debates regarding Indigenous peoples’ participation in land and resource decision-making in the context of impact assessment in Canada. While impact assessment is viewed as a mechanism through which Indigenous rights (including the Crown's duty to consult) are realized, the actors in these processes (federal government authorities, project promoters and indigenous groups) do not seem to agree on the meaning and scope of Indigenous participation norms, notably regarding free, prior and informed consent (FPIC). Through discourse analysis of these actors within the framework of the parliamentary work leading to the adoption of the Impact Assessment Act (2019), this research reveals three main conceptions of the place of Indigenous peoples in impact assessment decision-making processes: procedural, partnership and based on self-determination. This thesis also highlights important differences in terms of expectations regarding the type of participation and more specifically on FPIC interpretations. These differences are largely based on how they conceive decision-making authority in matters of territorial governance in Canada. For the government and the Indigenous actors, notions of participation and decision-making authority are based on legal foundations. In contrast, for the industry, the rationale behind Indigenous participation is rather economic and linked to its impact on project approval

    Demonstrating the model nature of the high-temperature superconductor HgBa2_2CuO4+Δ_{4+\Delta}

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    The compound HgBa2_2CuO4+Δ_{4+\Delta} (Hg1201) exhibits a simple tetragonal crystal structure and the highest superconducting transition temperature (Tc_c) among all single Cu-O layer cuprates, with Tc_c = 97 K (onset) at optimal doping. Due to a lack of sizable single crystals, experimental work on this very attractive system has been significantly limited. Thanks to a recent breakthrough in crystal growth, such crystals have now become available. Here, we demonstrate that it is possible to identify suitable heat treatment conditions to systematically and uniformly tune the hole concentration of Hg1201 crystals over a wide range, from very underdoped (Tc_c = 47 K, hole concentration p ~ 0.08) to overdoped (Tc_c = 64 K, p ~ 0.22). We then present quantitative magnetic susceptibility and DC charge transport results that reveal the very high-quality nature of the studied crystals. Using XPS on cleaved samples, we furthermore demonstrate that it is possible to obtain large surfaces of good quality. These characterization measurements demonstrate that Hg1201 should be viewed as a model high-temperature superconductor, and they provide the foundation for extensive future experimental work.Comment: 15 pages, 6 Figure

    Placement decisions and disparities among Aboriginal groups: An application of the Decision Making Ecology through multi-level analysis

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    a b s t r a c t Objective: This paper examined the relative influence of clinical and organizational characteristics on the decision to place a child in out-of-home care at the conclusion of a child maltreatment investigation. It tested the hypothesis that extraneous factors, specifically, organizational characteristics, impact the decision to place a child in out-of-home care. A secondary aim was to identify possible decision making influences related to disparities in placement decisions tied to Aboriginal children. Research suggests that the Aboriginal status of the child and structural risk factors affecting the family, such as poverty and poor housing, substantially account for this overrepresentation. Methods: The decision to place a child in out-of-home care was examined using data from the Canadian Incidence Study of Reported Child Abuse and Neglect. This child welfare dataset collected information about the results of nearly 5,000 child maltreatment investigations as well as a description of the characteristics of the workers and organization responsible for conducting those investigations. Multi-level statistical models were developed using MPlus software, which can accommodate dichotomous outcome variables, which are more reflective of decision making in child welfare. Mplus allows the specific case of the logistic link function for binary outcome variables under maximum likelihood estimation. Results: Final models revealed the importance of the number of Aboriginal reports to an organization as a key second level predictor of the placement decision. It is the only second level factor that remains in the final model. This finding was very stable when tested over several different levels of proportionate caseload representation ranging from greater than 50% to 20% of the caseload. Conclusions: Disparities among Aboriginal children in child welfare decision making were identified at the agency level. Practice implications: The study provides additional evidence supporting the possibility that one source of overrepresentation of Aboriginal children in the Canadian foster care system is a lack of appropriate resources at the agency or community level

    Encadrement normatif et contractuel des pratiques de téléconsultation en clinique de premiÚre ligne

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    Jusqu'Ă  la pandĂ©mie de la COVID-19, les services de tĂ©lĂ©consultation offerts par des mĂ©decins omnipraticiens au QuĂ©bec Ă©taient fortement limitĂ©s essentiellement parce qu'ils n'Ă©taient pas rĂ©munĂ©rĂ©s puisque non reconnus comme des actes mĂ©dicaux assurables. Le dĂ©cret du 16 mars 2020 , adoptĂ© dans le contexte d'urgence sanitaire, permet maintenant cette rĂ©munĂ©ration au mĂȘme titre que la rĂ©munĂ©ration associĂ©e Ă  la visite du patient en clinique. De nombreux avantages sont reconnus et associĂ©s Ă  la tĂ©lĂ©consultation en premiĂšre ligne si cette tĂ©lĂ©consultation est bien encadrĂ©e. Le prĂ©sent projet vise Ă  examiner les bonnes pratiques d'encadrement de la tĂ©lĂ©consultation et Ă  proposer des recommandations avant que ne soit nĂ©gociĂ© la prochaine entente de rĂ©munĂ©ration avec les mĂ©decins omnipraticiens. Nous recommandons notamment une formation obligatoire, une clarification lĂ©gislative quant au droit des assureurs privĂ©s de rembourser la tĂ©lĂ©consultation et des modalitĂ©s de rĂ©munĂ©ration variĂ©es en fonction du type de tĂ©lĂ©consultation. Il nous appert enfin impĂ©ratif de rapidement commander une Ă©tude dĂ©taillĂ©e sur les bĂ©nĂ©fices et les coĂ»ts de la tĂ©lĂ©consultation au QuĂ©bec

    Melting and differentiation of early-formed asteroids: The perspective from high precision oxygen isotope studies

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    A number of distinct methodologies are available for determining the oxygen isotope composition of minerals and rocks, these include laser-assisted fluorination, secondary ion mass spectrometry (SIMS)and UV laser ablation. In this review we focus on laser-assisted fluorination, which currently achieves the highest levels of precision available for oxygen isotope analysis. In particular, we examine how results using this method have furthered our understanding of early-formed differentiated meteorites. Due to its rapid reaction times and low blank levels, laser-assisted fluorination has now largely superseded the conventional externally-heated Ni “bomb” technique for bulk analysis. Unlike UV laser ablation and SIMS analysis, laser-assisted fluorination is not capable of focused spot analysis. While laser fluorination is now a mature technology, further analytical improvements are possible via refinements to the construction of sample chambers, clean-up lines and the use of ultra-high resolution mass spectrometers. High-precision oxygen isotope analysis has proved to be a particularly powerful technique for investigating the formation and evolution of early-formed differentiated asteroids and has provided unique insights into the interrelationships between various groups of achondrites. A clear example of this is seenin samples that lie close to the terrestrial fractionation line (TFL). Based on the data from conventional oxygen isotope analysis, it was suggested that the main-group pallasites, the howardite eucrite diogenite suite (HEDs) and mesosiderites could all be derived from a single common parent body. However,high precision analysis demonstrates that main-group pallasites have a Δ17O composition that is fully resolvable from that of the HEDs and mesosiderites, indicating the involvement of at least two parent bodies. The range of Δ17O values exhibited by an achondrite group provides a useful means of assessing the extent to which their parent body underwent melting and isotopic homogenization. Oxygen isotope analysis can also highlight relationships between ungrouped achondrites and the more well-populated groups. A clear example of this is the proposed link between the evolved GRA 06128/9 meteorites and the brachinites. The evidence from oxygen isotopes, in conjunction with that from other techniques, indicates that we have samples from approximately 110 asteroidal parent bodies (∌60 irons, ∌35 achondrites and stony-iron, and ∌15 chondrites) in our global meteorite collection. However, compared to the likely size of the original protoplanetary asteroid population, this is an extremely low value. In addition, almost all of the differentiated samples (achondrites, stony-iron and irons) are derived from parent bodies that were highly disrupted early in their evolution. High-precision oxygen isotope analysis of achondrites provides some important insights into the origin of mass-independent variation in the early Solar System. In particular, the evidence from various primitive achondrite groups indicates that both the slope 1 (Y&R) and CCAM lines are of primordial significance. Δ17O differences between water ice and silicate-rich solids were probably the initial source of the slope 1 anomaly. These phases most likely acquired their isotopic composition as a result of UV photo-dissociation of CO that took place either in the early solar nebula or precursor giant molecular cloud. Such small-scale isotopic heterogeneities were propagated into larger-sized bodies, such as asteroids and planets, as a result of early Solar System processes, including dehydration, aqueous alteration,melting and collisional interactions

    Pan-Cancer Analysis of lncRNA Regulation Supports Their Targeting of Cancer Genes in Each Tumor Context

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    Long noncoding RNAs (lncRNAs) are commonly dys-regulated in tumors, but only a handful are known toplay pathophysiological roles in cancer. We inferredlncRNAs that dysregulate cancer pathways, onco-genes, and tumor suppressors (cancer genes) bymodeling their effects on the activity of transcriptionfactors, RNA-binding proteins, and microRNAs in5,185 TCGA tumors and 1,019 ENCODE assays.Our predictions included hundreds of candidateonco- and tumor-suppressor lncRNAs (cancerlncRNAs) whose somatic alterations account for thedysregulation of dozens of cancer genes and path-ways in each of 14 tumor contexts. To demonstrateproof of concept, we showed that perturbations tar-geting OIP5-AS1 (an inferred tumor suppressor) andTUG1 and WT1-AS (inferred onco-lncRNAs) dysre-gulated cancer genes and altered proliferation ofbreast and gynecologic cancer cells. Our analysis in-dicates that, although most lncRNAs are dysregu-lated in a tumor-specific manner, some, includingOIP5-AS1, TUG1, NEAT1, MEG3, and TSIX, synergis-tically dysregulate cancer pathways in multiple tumorcontexts

    Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

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    Although theMYConcogene has been implicated incancer, a systematic assessment of alterations ofMYC, related transcription factors, and co-regulatoryproteins, forming the proximal MYC network (PMN),across human cancers is lacking. Using computa-tional approaches, we define genomic and proteo-mic features associated with MYC and the PMNacross the 33 cancers of The Cancer Genome Atlas.Pan-cancer, 28% of all samples had at least one ofthe MYC paralogs amplified. In contrast, the MYCantagonists MGA and MNT were the most frequentlymutated or deleted members, proposing a roleas tumor suppressors.MYCalterations were mutu-ally exclusive withPIK3CA,PTEN,APC,orBRAFalterations, suggesting that MYC is a distinct onco-genic driver. Expression analysis revealed MYC-associated pathways in tumor subtypes, such asimmune response and growth factor signaling; chro-matin, translation, and DNA replication/repair wereconserved pan-cancer. This analysis reveals insightsinto MYC biology and is a reference for biomarkersand therapeutics for cancers with alterations ofMYC or the PMN
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