4,207 research outputs found
Automated Protein Structure Classification: A Survey
Classification of proteins based on their structure provides a valuable
resource for studying protein structure, function and evolutionary
relationships. With the rapidly increasing number of known protein structures,
manual and semi-automatic classification is becoming ever more difficult and
prohibitively slow. Therefore, there is a growing need for automated, accurate
and efficient classification methods to generate classification databases or
increase the speed and accuracy of semi-automatic techniques. Recognizing this
need, several automated classification methods have been developed. In this
survey, we overview recent developments in this area. We classify different
methods based on their characteristics and compare their methodology, accuracy
and efficiency. We then present a few open problems and explain future
directions.Comment: 14 pages, Technical Report CSRG-589, University of Toront
A Machine Learning Based Analytical Framework for Semantic Annotation Requirements
The Semantic Web is an extension of the current web in which information is
given well-defined meaning. The perspective of Semantic Web is to promote the
quality and intelligence of the current web by changing its contents into
machine understandable form. Therefore, semantic level information is one of
the cornerstones of the Semantic Web. The process of adding semantic metadata
to web resources is called Semantic Annotation. There are many obstacles
against the Semantic Annotation, such as multilinguality, scalability, and
issues which are related to diversity and inconsistency in content of different
web pages. Due to the wide range of domains and the dynamic environments that
the Semantic Annotation systems must be performed on, the problem of automating
annotation process is one of the significant challenges in this domain. To
overcome this problem, different machine learning approaches such as supervised
learning, unsupervised learning and more recent ones like, semi-supervised
learning and active learning have been utilized. In this paper we present an
inclusive layered classification of Semantic Annotation challenges and discuss
the most important issues in this field. Also, we review and analyze machine
learning applications for solving semantic annotation problems. For this goal,
the article tries to closely study and categorize related researches for better
understanding and to reach a framework that can map machine learning techniques
into the Semantic Annotation challenges and requirements
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