6,842 research outputs found
Operationalising a Threshold Concept in Economics: A Pilot Study Using Multiple Choice Questions on Opportunity Cost
This paper addresses the emerging educational framework that envisions threshold concepts as mediators of learning outcomes. While the threshold concepts framework is highly appealing on a theoretical level, few researchers have attempted to measure threshold concept acquisition empirically. Achieving this would open a new arena for exploration and debate in the threshold concepts field, and provide potential results to inform teaching practice. We begin the process of operationalising threshold concepts in economics by attempting to measure students' grasp of the threshold concept of opportunity cost in an introductory economics class. We suggest two potential measures and correlate them with an array of ex ante and ex post variables, including students' expectations of success, prior misconceptions about economics and the work of economists, and actual success in the course. Results cast new light onto the factors that influence the acquisition of threshold concepts, the relationship between threshold concept acquisition and final learning outcomes, and the empirical viability of threshold concepts generally.
Heat transport in insulators from ab initio Green-Kubo theory
The Green-Kubo theory of thermal transport has long be considered
incompatible with modern simulation methods based on electronic-structure
theory, because it is based on such concepts as energy density and current,
which are ill-defined at the quantum-mechanical level. Besides, experience with
classical simulations indicates that the estimate of heat-transport
coefficients requires analysing molecular trajectories that are more than one
order of magnitude longer than deemed feasible using ab initio molecular
dynamics. In this paper we report on recent theoretical advances that are
allowing one to overcome these two obstacles. First, a general gauge invariance
principle has been established, stating that thermal conductivity is
insensitive to many details of the microscopic expression for the energy
density and current from which it is derived, thus permitting to establish a
rigorous expression for the energy flux from Density-Functional Theory, from
which the conductivity can be computed in practice. Second, a novel data
analysis method based on the statistical theory of time series has been
proposed, which allows one to considerably reduce the simulation time required
to achieve a target accuracy on the computed conductivity. These concepts are
illustrated in detail, starting from a pedagogical introduction to the
Green-Kubo theory of linear response and transport, and demonstrated with a few
applications done with both classical and quantum-mechanical simulation
methods.Comment: 36 pages, 14 figure
New Approaches To Photometric Redshift Prediction Via Gaussian Process Regression In The Sloan Digital Sky Survey
Expanding upon the work of Way and Srivastava 2006 we demonstrate how the use
of training sets of comparable size continue to make Gaussian process
regression (GPR) a competitive approach to that of neural networks and other
least-squares fitting methods. This is possible via new large size matrix
inversion techniques developed for Gaussian processes (GPs) that do not require
that the kernel matrix be sparse. This development, combined with a
neural-network kernel function appears to give superior results for this
problem. Our best fit results for the Sloan Digital Sky Survey (SDSS) Main
Galaxy Sample using u,g,r,i,z filters gives an rms error of 0.0201 while our
results for the same filters in the luminous red galaxy sample yield 0.0220. We
also demonstrate that there appears to be a minimum number of training-set
galaxies needed to obtain the optimal fit when using our GPR rank-reduction
methods. We find that morphological information included with many photometric
surveys appears, for the most part, to make the photometric redshift evaluation
slightly worse rather than better. This would indicate that most morphological
information simply adds noise from the GP point of view in the data used
herein. In addition, we show that cross-match catalog results involving
combinations of the Two Micron All Sky Survey, SDSS, and Galaxy Evolution
Explorer have to be evaluated in the context of the resulting cross-match
magnitude and redshift distribution. Otherwise one may be misled into overly
optimistic conclusions.Comment: 32 pages, ApJ in Press, 2 new figures, 1 new table of comparison
methods, updated discussion, references and typos to reflect version in Pres
A congruent phylogenomic signal places eukaryotes within the Archaea
Determining the relationships among the major groups of cellular life is important for understanding the evolution of biological diversity, but is difficult given the enormous time spans involved. In the textbook ‘three domains’ tree based on informational genes, eukaryotes and Archaea share a common ancestor to the exclusion of Bacteria. However, some phylogenetic analyses of the same data have placed eukaryotes within the Archaea, as the nearest relatives of different archaeal lineages. We compared the support for these competing hypotheses using sophisticated phylogenetic methods and an improved sampling of archaeal biodiversity. We also employed both new and existing tests of phylogenetic congruence to explore the level of uncertainty and conflict in the data. Our analyses suggested that much of the observed incongruence is weakly supported or associated with poorly fitting evolutionary models. All of our phylogenetic analyses, whether on small subunit and large subunit ribosomal RNA or concatenated protein-coding genes, recovered a monophyletic group containing eukaryotes and the TACK archaeal superphylum comprising the Thaumarchaeota, Aigarchaeota, Crenarchaeota and Korarchaeota. Hence, while our results provide no support for the iconic three-domain tree of life, they are consistent with an extended eocyte hypothesis whereby vital components of the eukaryotic nuclear lineage originated from within the archaeal radiation
Patterns of prokaryotic lateral gene transfers affecting parasitic microbial eukaryotes
Background: The influence of lateral gene transfer on gene origins and biology in eukaryotes is poorly understood compared with those of prokaryotes. A number of independent investigations focusing on specific genes, individual genomes, or specific functional categories from various eukaryotes have indicated that lateral gene transfer does indeed affect eukaryotic genomes. However, the lack of common methodology and criteria in these studies makes it difficult to assess the general importance and influence of lateral gene transfer on eukaryotic genome evolution. Results: We used a phylogenomic approach to systematically investigate lateral gene transfer affecting the proteomes of thirteen, mainly parasitic, microbial eukaryotes, representing four of the six eukaryotic super-groups. All of the genomes investigated have been significantly affected by prokaryote-to-eukaryote lateral gene transfers, dramatically affecting the enzymes of core pathways, particularly amino acid and sugar metabolism, but also providing new genes of potential adaptive significance in the life of parasites. A broad range of prokaryotic donors is involved in such transfers, but there is clear and significant enrichment for bacterial groups that share the same habitats, including the human microbiota, as the parasites investigated. Conclusions: Our data show that ecology and lifestyle strongly influence gene origins and opportunities for gene transfer and reveal that, although the outlines of the core eukaryotic metabolism are conserved among lineages, the genes making up those pathways can have very different origins in different eukaryotes. Thus, from the perspective of the effects of lateral gene transfer on individual gene ancestries in different lineages, eukaryotic metabolism appears to be chimeric
Physical properties of interstellar filaments
We analyze the physical parameters of interstellar filaments that we describe
by an idealized model of isothermal self-gravitating infinite cylinder in
pressure equilibrium with the ambient medium. Their gravitational state is
characterized by the ratio f_cyl of their mass line density to the maximum
possible value for a cylinder in a vacuum. Equilibrium solutions exist only for
f_cyl < 1. This ratio is used in providing analytical expressions for the
central density, the radius, the profile of the column density, the column
density through the cloud centre, and the fwhm. The dependence of the physical
properties on external pressure and temperature is discussed and directly
compared to the case of pressure-confined isothermal self-gravitating spheres.
Comparison with recent observations of the fwhm and the central column
density N_H(0) show good agreement and suggest a filament temperature of ~10 K
and an external pressure p_ext/k in the range 1.5x10^4 K/cm^3 to 5x10^4 K/cm^3.
Stability considerations indicate that interstellar filaments become
increasingly gravitationally unstable with mass line ratio f_cyl approaching
unity. For intermediate f_cyl>0.5 the instabilities should promote core
formation through compression, with a separation of about five times the fwhm.
We discuss the nature of filaments with high mass line densities and their
relevance to gravitational fragmentation and star formation.Comment: 18 pages, 12 figures accepted for publication (13/4/2012
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Performance-based building and innovation: Balancing client and industry needs
One reason for the interest in performance-based building is that it is commonly advocated as a powerful way of enhancing innovation performance by articulating building performance outcomes, and by offering relevant procurement actors the discretion to innovate to meet these performance requirements more effectively and/or efficiently. The paper argues that the current approach to performance-based building assumes that relevant actors have the capacity, ability and motivation to innovate from a business perspective. It is proposed that the prevailing conceptualization of PBB is too restrictive and should be broadened explicitly to accommodate the required business logic that must be in place before actors will innovate. The relevant performance-based building and innovation literature is synthesized to support the assertion. The paper concludes with an innovation-focused definition of performance-based building
Evidence of Detrimental Effects of Environmental Contaminants on Growth and Reproductive Physiology of White Sturgeon in Impounded Areas of the Columbia River
This study sought to determine whether wild white sturgeon from the Columbia River (Oregon) were exhibiting signs of reproductive endocrine disruption. Fish were sampled in the free-flowing portion of the river (where the population is experiencing reproductive success) and from three reservoirs behind hydroelectric dams (where fish have reduced reproductive success). All of the 18 pesticides and almost all of the 28 polychlorinated biphenyls (PCBs) that were analyzed in livers and gonads were detected in at least some of the tissue samples. Metabolites of p,p′-dichlorodiphenyltrichloroethane (DDT) [p,p′-dichlorodiphenyldichloroethylene (DDE) and p,p′-1,1-dichloro-2,2-bis(4-chlorophenyl)ethane (DDD)] were consistently found at relatively high levels in fish. Some males and immature females showed elevated plasma vitellogenin; however, concentrations were not correlated with any of the pesticides or PCBs analyzed. Negative correlations were found between a number of physiologic parameters and tissue burdens of toxicants. Plasma triglycerides and condition factor were negatively correlated with total DDT (DDD + DDE + DDT), total pesticides (all pesticides detected – total DDT), and PCBs. In males, plasma androgens and gonad size were negatively correlated with total DDT, total pesticides, and PCBs. Fish residing in the reservoir behind the oldest dam had the highest contaminant loads and incidence of gonadal abnormalities, and the lowest triglycerides, condition factor, gonad size, and plasma androgens. These data suggest that endocrine-disrupting chemicals may be accumulating behind dams over time. Overall, results of this study indicate that exposure to environmental contaminants may be affecting both growth and reproductive physiology of sturgeon in some areas of the Columbia River
A chiral topological add-drop filter for integrated quantum photonic circuits
The integration of quantum emitters within topological nano-photonic devices
opens up new avenues for the control of light-matter interactions at the single
photon level. Here, we realise a spin-dependent, chiral light-matter interface
using individual semiconductor quantum dots embedded in a topological add-drop
filter. The filter is imprinted within a valley-Hall photonic crystal (PhC)
membrane and comprises a resonator evanescently coupled to a pair of access
waveguides. We show that the longitudinal modes of the resonator enable the
filter to perform wavelength-selective routing of light, protected by the
underlying topology. Furthermore, we demonstrate that for a quantum dot located
at a chiral point in the resonator, selective coupling occurs between
well-defined spin states and specific output ports of the topological device.
This behaviour is fundamental to the operation of chiral devices such as a
quantum optical circulator. Our device therefore represents a
topologically-protected building block with potential to play an enabling role
in the development of chiral integrated quantum photonic circuits
The description of F2 at small x incorporating angular ordering
We study the perturbative QCD description of the HERA measurements of using a gluon distribution that is obtained from an evolution
incorporating angular ordering of the gluon emissions, and which embodies both
GLAP and BFKL dynamics. We compare the predictions with recent HERA data for
. We present estimates of the charm component and of .Comment: 8 LaTeX pages + 4 uuencoded figure
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