Estimation of composition of quinoa (Chenopodium quinoa Willd.) grains by Near-Infrared Transmission spectroscopy

The aim of this study was to develop robust chemometric models for the routine determination of dietary constituents of quinoa (Chenopodium quinoa Willd.) using Near-Infrared Transmission (NIT) spectroscopy. Spectra of quinoa grains of 77 cultivars were acquired while dietary constituents were determined by reference methods. Spectra were subjected to multiplicative scatter correction (MSC) or extended multiplicative signal correction (EMSC), and were (or not) treated by Savitzky-Golay (SG) filters. Latent variables were extracted by partial least squares regression (PLSR) or canonical powered partial least squares (CPPLS) algorithms, and the accuracy and predictability of all modelling strategies were compared. Smoothing the spectra improved the accuracy of the models for fat (root mean square error of cross-validation, RMSECV: 0.3190.327%), ashes (RMSECV: 0.2240.230%), and particularly for protein (RMSECV: 0.5180.564%) and carbohydrates (RMSECV: 0.5420.559%), while enhancing the prediction performance, particularly, for fat (root mean square error of prediction, RMSEP: 0.2480.335%) and ashes (RMSEP: 0.1370.191%). Although the highest predictability was achieved for ashes (SG-filtered EMSC/PLSR: bootstrapped 90% confidence interval for RMSEP: [0.3760.512]) and carbohydrates (SG-filtered MSC/CPPLS: 90% CI RMSEP: [0.6510.901]), precision was acceptable for protein (SG-filtered MSC/CPPLS: 90% CI RMSEP: [0.6500.852]), fat (SG-filtered EMSC/CPPLS: 90% CI RMSEP: [0.4780.654]) and moisture (non-filtered EMSC/PLSR: 90% CI RMSEP: [0.6580.833]).Mr. Encina-Zelada acknowledges the financial aid provided by the Peruvian National Programme of Scholarships and Student Loans (PRONABEC) in the mode of PhD grants (Presidente de La República Grant Number 183308). Dr. Gonzales-Barron wishes to acknowledge the financial support provided by the Portuguese Foundation for Science and Technology (FCT) through the award of a five-year Investigator Fellowship (IF) in the mode of Development Grants (IF/00570)

Heart Rate Variability as Biomarker for Prognostic of Metabolic Disease

Lifestyle emerging diseases like obesity, metabolic syndrome (MeS), and diabetes mellitus are considered high-risk factors for lethal arrhythmias and side effects. A Poincaré plot is constructed with the time series of RR and PP electrocardiogram (ECG) intervals, using two stages: the new phase and the old phase. We proposed this diagram of two dimensions, a way to quantify and observe the regularity of events in space and time. Therefore, the heart rate variability (HRV) can be used as a biomarker for early prognostic and diagnostic of several metabolic diseases; additionally, this biomarker is obtained by a noninvasive tool like the electrocardiogram

La imagen y la narrativa como herramientas para el abordaje psicosocial en escenarios de violencia en la Ciudad de Ibagué, Departamento del Tolima.

Este apartado, pretende mostrar la realidad de la violencia del conflicto armado en escenarios colombianos, que por cerca de 50 años, ocasionó una fractura social, dejando a miles de civiles afectados por una guerra, que no pareciera que no tuviera fin. Para ello, el estado y organizaciones restablecedoras de derechos de las víctimas del conflicto armado, crearon programas y recolectaron una serie de historias de los diversos hechos y manifestaciones de violencia por las cuales la ciudadanía tuvo que pasar. Basados en los relatos de las víctimas, se trabajó con la identificación de elementos resilientes, violencia naturalizada e impactos psicosociales de mayor trascendencia, focalizados a través del Análisis de relatos como el de Carlos Arturo (desplazado por la violencia), a partir de la formulación de preguntas circulares, reflexivas y estratégicas, que den pie para obtención y reconocimiento de información para el facilitador y persona misma en su proceso terapéutico. A su vez, se encuentra el análisis y presentación de estrategias de abordaje psicosocial, para el caso de las comunidades de Cacarica, y el informe analítico y reflexivo de la experiencia de un foto voz realizado, con el fin de observar los procesos psicosociales por los que atraviesan, y reconocer o plantear, según sea el caso, una estrategia que permite mejorar las condiciones de vida de determinada poblaciónThis section, aims to show the reality of the violence of the armed conflict in Colombian settings, for about 50 years, caused a social fracture, leaving thousands of civilians affected by a war, which did not seem to have no end. For this, the state and organizations that restore rights to the victims of the armed conflict, created programs and collected a series of stories of the various events and manifestations of violence that citizens had to go through. Based on the stories of the victims, we worked with the identification of resilient elements, naturalized violence and the most important psychosocial impacts, focused through the Analysis of stories such as Carlos Arturo (displaced by violence), based from the creation of circular, reflexive and strategic questions, that give rise to obtaining and recognizing information for the facilitator and the person himself in his therapeutic process. Similarly, there is the analysis and presentation of psychosocial approach strategies on the case of the communities of Cacarica. This analytical and reflective report, shows the psychosocial destructuring that causes the armed conflict to violate the habitats of these communities and violate the cultural memory that identified them as collectiv

Creación de empresa

El manual presentado describe las particularidades concernientes a la modalidad de grado de Creación de empresa de la Facultad de Diseño, Comunicación y Bellas Artes con el fin de que los futuros graduados puedan, de acuerdo a sus intereses personales y profesionales, direccionar con mayor precisión el tipo de emprendimiento que deseen seleccionar y con el cual puedan desarrollar sus capacidades creativas y de innovación. La creación de empresa como opción de grado se estructura desde el desarrollo de un plan de negocio que se aborda desde diferentes aspectos como: la definición del tipo de emprendimiento, la generación de una idea de negocio que justifique la pertinencia del proyecto con relación a su disciplina, estructuración de la filosofía institucional, comercial, operativa, legal, financiera con el fin de dar viabilidad a su propuesta de manera sostenible dentro del sector económico real a mediano y largo plazo

Estimation of Proximate Composition of Quinoa (Chenopodium quinoa, Willd.) Flour by Near-Infrared Transmission Spectroscopy

The aim of this study was to develop chemometric models for protein, fat, ashes and carbohydrates contents of quinoa flour using Near-Infrared Transmission (NIT) spectroscopy. Spectra of quinoa flour obtained from grains of 70 different cultivars were scanned while dietary constituents were determined by reference AOAC methods. As a pre-treatment, spectra were subjected to extended multiplicative signal correction (EMSC) with polynomial degree 0, 1 or 2. Next, the Canonical Powered Partial Least Squares (CPPLS) algorithm was applied, and models were compared in terms of accuracy and predictability. For all models, root mean square errors of cross-validation (RMSECV), root meat square errors of prediction (RMSEP) and coefficient of correlation of cross-validation (RCV) were computed. Robust models were obtained when quinoa spectra were pre-processed using EMSC of polynomial degree 2 for both fat (RMSECV: 0.268% and RMSEP: 0.256%) and carbohydrates (RMSECV: 0.641% and RMSEP: 0.643%) following extraction of five CPPLS latent variables. Good coefficients of correlation of prediction (RP: 0.6900.821) were found for all constituents when models were validated on a test data set consisting of 13 quinoa flour spectra. Thus, good predictions of the dietary constituents of quinoa flour could be achieved by using NIT technology, as implied by the low coefficient of variation of prediction (CVP): 5.64% for protein, 3.88% for fat 7.32% for ashes and 0.80% for carbohydrates contents.info:eu-repo/semantics/publishedVersio

Prognostic significance of mutation type and chromosome fragility in Fanconi anemia

Fanconi anemia (FA) is a rare genetic disease characterized by high phenotypic and genotypic heterogeneity, and extreme chromosome fragility. To better understand the natural history of FA, identify genetic risk and prognostic factors, and develop novel therapeutic strategies, the Spanish Registry of Patients with FA collects data on clinical features, chromosome fragility, genetic subtypes, and DNA sequencing with informed consent of participating individuals. In this article, we describe the clinical evolution of 227 patients followed up for up to 30 years, for whom our data indicate a cumulative cancer incidence of 86% by age 50. We found that patients with lower chromosome fragility had a milder malformation spectrum and better outcomes in terms of later-onset hematologic impairment, less severe bone marrow failure, and lower cancer risk. We also found that outcomes were better for patients with mutations leading to mutant FANCA protein expression (genetic hypomorphism) than for patients lacking this protein. Likewise, prognosis was consistently better for patients with biallelic mutations in FANCD2 (mainly hypomorphic mutations) than for patients with biallelic mutations in FANCA and FANCG, with the lack of the mutant protein in patients with biallelic mutations in FANCG contributing to their poorer outcomes. Our results regarding the clinical impact of chromosome fragility and genetic hypomorphism suggest that mutant FA proteins retain residual activity. This finding should encourage the development of novel therapeutic strategies aimed at partially or fully enhancing mutant FA function, thereby preventing or delaying bone marrow failure and cancer in patients with FA

Garanticemos la calidad de las muestras respiratorias para diagnosticar COVID-19

This article and video describes the procedures for the collection of respiratory swabs that guarantee biosecurity and the diagnosis of COVID-19 in adults and children.Este artículo y video disponibles en el OJS de la Revista describe los procedimientos para la recolección de hisopos respiratorios que garantizan la bioseguridad y el diagnóstico de COVID-19 en adultos y niños

Sistema de información para generación de informes estadísticos estandarizados provenientes del seguimiento y evaluación a practicantes de la Universidad de Cartagena

Tesis (Ingeniero de Sistemas).--Universidad de Cartagena. Facultad de Ciencias E Ingenierías. Programa de Ingeniería de Sistemas, 2016El presente trabajo de grado tuvo como propósito desarrollar un sistema de información para la generación de informes estadísticos estandarizados provenientes del seguimiento y evaluación a practicantes de la Universidad de Cartagena. Para dar cumplimiento a este objetivo se planteó una investigación en las universidades de la ciudad con el fin de obtener información de las plataformas usadas por estos, a su vez se entrevistaron diferentes programas de la universidad de Cartagena para conocer sus necesidades actuales en cuanto al manejo de los informes estadístico