Caso clínico: tumor glómico agresivo de localización lingual

El tumor glómico es una neoplasia benigna que se origina en las células musculares lisas del glomus vascular. Los glomagiomas de cabeza y cuello son raros, con una incidencia del 0,6%. Presentamos un caso clínico de tumor glómico recidivante, localizado originalmente en la lengua, con un comportamiento clínico agresivo que complicó las opciones terapeuticas del caso.A glomus tumor or glomangioma is a benign neoplasm originating from the modified smooth muscle cells of the vascular glomus Glomangiomas of the head and/or neck are extremely rare, with an incidence of 0.6%. We present an observational case report of a recurrent glomic tumor originally located in the mobile tongue , with an aggressive clinical course that complicated the therapeutic options of the case

Mòdul de suport a la docència per assignatures de programació

El propòsit d'aquest projecte és el d'ajudar a simplificar l'ensenyament de certs conceptes de programació que són difícils d'entendre per a alumnes de primer de carrera. Per aconseguir aquest propòsit és necessari l'ús d'un programa debugger, l'automatització de l'entrada de comandes d'aquest debugger en funció del programa a analitzar i, per últim, la visualització esquemàtica i didàctica dels resultats obtinguts. Tota aquesta simplificació serà realitzada amb una simple execució del projecte mitjançant un programa de control del DOS, que conté les diferents ordres per cridar de forma seqüencial a cada una de les parts del projecte.The purpose of this project is to help simplify the teaching of certain programming concepts that are difficult to understand for students at the first steps of their degree . To achieve this purpose it is necessary to use a debugger program, the automation of the debugger command entry aligning commands with the requirements depending on the program to be analyzed and, finally, a schematic and didactic display for the results. All this simplification will be made with a simple project execution through a DOS control program that contains different lines to call secuencially every one of the sections of the project.El propósito de este proyecto es el de ayudar a simplificar la enseñanza de ciertos conceptos de programación que son difíciles de entender para alumnos de primero de carrera. Para conseguir este propósito es necesario el uso de un programa debugger, la automatización de la entrada de pedidos de este debugger en función del programa a analizar y, por último, la visualización esquemática y didáctica de los resultados obtenidos. Toda esta simplificación será realizada con una simple ejecución del proyecto mediante un programa de control del DOS, que contiene las diferentes órdenes para llamar de forma secuencial a cada una de las partes del proyecto

Reconstruction of the time-dependent electronic wave packet arising from molecular autoionization

Autoionizing resonances are paradigmatic examples of two-path wave interferences between direct photoionization, which takes a few attoseconds, and ionization via quasi-bound states, which takes much longer. Time-resolving the evolution of these interferences has been a long-standing goal, achieved recently in the helium atom owing to progress in attosecond technologies. However, already for the hydrogen molecule, similar time imaging has remained beyond reach due to the complex interplay between fast nuclear and electronic motions. We show how vibrationally resolved photoelectron spectra of H2 allow one to reconstruct the associated subfemtosecond autoionization dynamics by using the ultrafast nuclear dynamics as an internal clock, thus forgoing ultrashort pulses. Our procedure should be general for autoionization dynamics in molecules containing light nuclei, which are ubiquitous in chemistry and biologyThis work was supported by European Research Council advanced grant 290853-XCHEM within the seventh framework program of the European Union. We also acknowledge the financial support from MINECO projects FIS2013-42002-R and FIS2016-77889-R, and the European COST (Cooperation in Science and Technology) Action XLIC CM1204, and the computer time from the Centro de Computación Científica de la Universidad Autónoma de Madrid and Marenostrum Supercomputer Center. A.P. acknowledges a Ramón y Cajal contract from the Ministerio de Economía y Competitividad (Spain). F.M. acknowledges support from the “Severo Ochoa” Programme for Centres of Excellence in R&D (MINECO, grant SEV-2016-0686) and the “María de Maeztu” Programme for Units of Excellence in R&D (MDM-2014-0377). S.E.C. acknowledges funding from the Helmoltz Recognition Award. The Extreme Light Infrastructure Attosecond Light Pulse Source project (GINOP-2.3.6-15-2015-00001) was financed by the European Union and cofinanced by the European Regional Development Fun

Estrategias a nivel de macro y micro-planificación en un prototipo de verbalización de ontologías

En este trabajo se presenta un primer prototipo de un trabajo de generación de lenguaje natural capaz de procesar el contenido de una ontología y generar un texto en lenguaje natural. El texto resultante debe estar organizado y expresado con una sintaxis aceptable, para que sea accesible a cualquier usuario cuyo interés sea el dominio modelado, pero no tenga las herramientas necesarias para comprender las lógicas subyacentes.Workshop: WISS – Innovación en Sistemas de SoftwareRed de Universidades con Carreras en Informátic

Impacto de la histocompatibilidad HLA sobre la función renal pos-trasplante en receptores de riñón en Colombia: ¿realmente importa el match?

Uno de los descubrimientos más relevantes en el campo de los trasplantes y en la inmunología en general ha sido el descubrimiento del Complejo Mayor de Histocompatibilidad (MHC por sus siglas en ingles). En humanos, la expresión del MHC se conoce como el Antígeno Leucocitario Humano (HLA por sus siglas en ingles) el cual se encuentra mapeado dentro del genoma humano en el brazo corto del cromosoma 6. Conocer el HLA de un donante y un receptor antes del trasplante se ha convertido en una práctica mundialmente aceptada ya que actualmente se conoce que la mayor carga de la respuesta inmunológica contra un órgano trasplantado está principalmente enfocada en los antígenos que expresan los genes codificados en esta región. Así mismo el desarrollo de anticuerpos después del trasplante contra los diferentes antígenos expresados en el HLA es un marcador importante para definir si existe o no un rechazo en curso y de esta forma predecir el pronóstico de un trasplante.Otr

Newtonian Cosmology in theories of modified gravity.

Trabajo de fin de Grado. Grado en Física. Curso académico 2020-2021[ES]En este trabajo se estudia la evolución de un universo que contiene un gas de partículas no relativistas sometidas a la fuerza de la gravedad. Se empieza analizando el problema de una evolución que sigue la ley de gravitación de newton, en el que se busca una solución tanto analítica como numéricamente. En particular se obtiene de esta manera una evolución comóvil y una ley de Hubble isótropa, lo que se podrá observar en distintas representaciones de evoluciones de distintos parámetros del problema, como radios o factores de escala y de Hubble. Resuelto el caso newtoniano se proponen tres cambios distintos en la ley de gravitación de newton y se obtienen las soluciones de manera numérica. Estos cambios son: introducir masa al gravitón, considerar que la interacción se expande a más dimensiones y considerar otra interacción repulsiva, los cuales llevarán consigo una modificación en la ley de gravitación que da lugar a distintas evoluciones, que dejarán de ser comóviles y tendrán un diagrama de Hubble anisótropo. Con ello se estudia y compara estas soluciones analizando cuales son los detalles importantes que aparecen en cada una[EN]In this paper we study the evolution of a universe that contain a nonrelativistic particle gas which is under the gravitacional force. We begin by analyzing the problem of an evolution that follows newton’s gravitational law and we look for a solution both analytically and numerically. Specifically we obtain by this way a comoving evolution and a isotropic hubble law, which ca be observed in representations of evolutions of differents parameters of the problem, such us radios or scales and hubble factors. When the resolution of the newtonian case has taken place, we propose three different changes into the newton’s gravitational law to obtain their solutions by a numerical way. These changes are: to introduce a mass to the graviton, to consider that the interaction can be expanded into more dimensions and to consider another repulsive interaction. Each one involve a variation in the gravitational law which result in different evolutions which will cease to be comoving and will have an anisotropic hubble diagram. We study and compare these solutions by analyzing the most important details in each on

Synthesis of chromatography adsorbent immobilized metal affinity (IMAC) from agarose and effect of the amount of NaBH4 in the derivatization step

A synthesis of IMAC adsorbent was performed. Agarose matrix was derivatized with epichlorohydrin using different amounts of NaBH4. Furthermore, iminodiacetic acid was immobilized on the modified agarose. Finally, the derivatization efficiency was studied by measuring the epoxide groups and retention of Cu2+. The results indicated that the matrices were modified efficiently and the use of NaBH4 in small amounts is enough to provide a reducing environment to the reaction.Fil: Romero, Marcelo Ricardo. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Conicet - Córdoba. Instituto Multidisciplinario de Biología Vegetal. Universidad Nacional de Córdoba. Facultad de Ciencias Exactas Físicas y Naturales. Instituto Multidisciplinario de Biología Vegetal; ArgentinaFil: Slenk, Walter. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Montero, Felipe. Universidad Nacional de Córdoba. Facultad de Ciencias Químicas; ArgentinaFil: Juárez Data, Roger Martín Noé. Consejo Nacional de Investigaciones Científicas y Técnicas. Centro Científico Tecnológico Bahía Blanca. Planta Piloto de Ingeniería Química (I). Grupo Vinculado al Plapiqui - Investigación y Desarrollo en Tecnología Química; Argentin

Characterization of Red Wines from Macaronesia

Wines from the Atlantic Islands of Macaronesia come from unusual terroirs due to their volcanic soils and the tropical and subtropical climatic conditions from this region. Some of these Islands produce highly appreciated fortified wines traded around the world since the sixteenth century, such as Madeira or Canary. Nowadays their distinct winemaking techniques and sweet wine traditions combine with the production of table wines. Previous studies described peculiar properties in wines from these regions, mostly related with their phenolic content and color, which are particularly important in the less produced red wines. The main purpose of this chapter is to characterize red wines produced in the Atlantic Islands of Macaronesia in terms of oenological and physico-chemical properties. Wines from these islands are extremely atypical, as their climates conditions are exceptional and red grape cultivars are exclusive. Furthermore, specific viticulture techniques are applied in these latitudes to proportionate the unique characteristics outlined in this work. Original experimental data from 300 red wines produced in 8 Atlantic islands from Canary and Cape Verde archipelago and an important reviewing study for Azores and Madeira red wines are considered herein. Results are presented according to archipelago

On the Integration of Grassmannian Constellations into LTE Networks: a Link-level Performance Study

This paper presents Grassmannian signaling as a transmission scheme that can be integrated in Long Term Evolution (LTE) to support higher user speeds and to increase the throughput achievable in the high Signal to Noise Ratio (SNR) regime. This signaling is compared, under realistic channel assumptions, with the diversity transmission modes standardized in LTE, in particular, Space-Frequency Block Coding and Frequency-Switched Transmit Diversity for two and four transmit antennas, respectively. In high-speed scenarios, and even with high antenna correlation, Grassmannian signaling outperforms the LTE diversity transmission modes starting from four transmit antennas. Furthermore, in the high SNR regime, Grassmannian signaling can increase the link data rate up to 10% and 15% for two and four antennas, respectively

Low-Latency Infrastructure-Based Cellular V2V Communications for Multi-Operator Environments With Regional Split

[EN] Mobile network operators are interested in providing Vehicle-to-Vehicle (V2V) communication services using their cellular infrastructure. Regional split of operators is one possible approach to support multi-operator infrastructure-based cellular V2V communication. In this approach, a geographical area is divided into non-overlapping regions, each one served by a unique operator. Its main drawback is the communication interruption motivated by the inter-operator handover in border areas, which prevents the fulfillment of the maximum end-to-end (E2E) latency requirements of fifth generation (5G) V2V services related to autonomous driving. In this work, we enable a fast inter-operator handover based on the pre-registration of the users on multiple operators, which substantially reduces the handover time to guarantee maximum E2E latency values of 100 ms in non-congested scenarios. To further reduce the latency of time-critical services to always less than 70 ms, even with the handover interruption time, while providing a latency around 20 ms in the majority of locations, we propose to complement the former technique with a mobile edge computing approach. Our proposal consists in the localization of application servers and broadcasting entities in all the base stations, to avoid the communication through the core network, together with the use of a new set of nodes in the base stations of cross-border areas called inter-operator relays, to minimize the communication latency between operators. Based on analytic and simulation results, it is demonstrated that the proposed techniques are effective to support low-latency infrastructure-based cellular V2V communications in multi-operator environments with regional split.The work of S. Roger was partially supported by the Spanish Ministry of Science, Innovation and Universities through grant number RYC-2017-22101.Martín-Sacristán, D.; Roger, S.; Garcia-Roger, D.; Monserrat Del Río, JF.; Spapis, P.; Zhou, C.; Kaloxylos, A. (2021). Low-Latency Infrastructure-Based Cellular V2V Communications for Multi-Operator Environments With Regional Split. IEEE Transactions on Intelligent Transportation Systems. 22(2):1052-1067. https://doi.org/10.1109/TITS.2019.29620971052106722