SDE WEAK APPROXIMATION LIBRARY (SDE WA) (VERSION 1.0)

In application of mathematical finance to practical problems, weak approximation of stochastic differential equations (SDEs) is one of the most important themes.In probabilistic approach to this problem, the Euler-Maruyama scheme which is a first-order weak approximation scheme has been used. Kusuoka recently proposed a weak approximation schceme for diffusion processes. Lyons andVictoir extensively developed the idea of this scheme to establish the cubature formula on the Weiner space. These results and the spread of quasi Monte Carlo method showed the efficiency of higher-order weak approximation which is often called Kusuoka approximation or KLV scheme. Ninomiya-Victoir and Ninomiya-Ninomiya successfully constructed algorithms of this scheme. These algorithms have been improved in a number of research. (Fujiwara, Ooshima-Teichman-Veluscek, etc.) The author constructed a universal numerical library written inCfor calculation of weak approximation of any fiven SDEs following the Kusuoka scheme. Two types of algorithms mentioned above (NV and NN) of the Kusuoka scheme are included in this library. The Euler-Maruyama scheme is also available in this library. The source code for this library can be obtained by downloading it from https://sites.google.com/site/marikoninomiya/

Power-stage frequency response cancellation of DC-DC converter with digital control

Recently, the performance of the DSP and FPGA is developed remarkably. So, fully digital control is enabled in switch mode power supplies. However, in many cases, the control system is built by very complicatedly and very difficult theories such as the adaptive control. Furthermore, in most popular PID control, its design method of the parameters is not clear, so derivation of the optimal parameters is very difficult. This paper proposes the interesting control technique which is cancelled the transfer function of the converter by using pole-zero-cancellation method. This technique is very simple and easy to stability design.2010 International Symposium on Power Electronics, Electrical Drives, Automation and Motion (SPEEDAM 2010) : Pisa, Italy, 2010.06.14-2010.06.1

Thiamine tetrahydrofurfuryl disulfide promotes voluntary activity through dopaminergic activation in the medial prefrontal cortex

A physically active lifestyle is associated with better health in body and mind, and it is urgent that supporting agents for such lifestyles be developed. In rodents, voluntary locomotor activity as an active physical behavior may be mediated by dopaminergic neurons (DNs). Thiamine phosphate esters can stimulate DNs, and we thus hypothesized that thiamine tetrahydrofurfuryl disulfide (TTFD), a thiamine derivative, promotes locomotor activity via DNs in rats. Acute i.p. administration of TTFD enhanced rat locomotor activity in a normal cage. In vivo microdialysis revealed that TTFD-enhanced locomotor activity was synchronized with dopamine release in the medial prefrontal cortex (mPFC). Antagonism of the dopamine D1 receptor, but not D2 receptor, in the mPFC fully suppressed TTFD-enhanced locomotor activity. Finally, we found a TTFD dose-dependent increase in voluntary wheel running. Our findings demonstrate that DNs in the mPFC mediates TTFD-enhanced locomotor activity, suggesting the potential of TTFD to induce active physical behavior

マルチメディアを用いた地域連携のプラットフォームづくり１～家政福祉を基盤とした保育士養成～

　本稿は、2020年度から3年計画で進めている児童福祉コースの取り組みについての経過報告である。設置3年目を迎えた和洋女子大学家政学部家政福祉学科児童福祉コースは、保育・福祉・家政の専門性をそなえた保育士養成を一貫して目指してきた。その多彩な学びの集大成として、プロジェクトでは、マルチメディアを用いた地域連携のプラットフォームの構築に取り組んでいる。具体的には、障害の有無や年齢、性別等にかかわらず、一人一人が輝けるインクルーシブな場を、児童福祉コースの科目間で連携を図りながら、学生主体で創り上げていき、最終的にユニバーサルダンスの創造と発表を目指す。　このプロジェクトは、2020年度と2021年度に和洋女子大学教育振興支援助成を受けており、最終年度を2022年度と想定している。本稿で、2020～2021年度前期までの活動状況を整理し、今後の方向性を示したい

児童福祉コースによる地域連携プロジェクトの取り組み～ マルチメディアを用いた地域連携のプラットフォームづくり２～令和２（2020）年度～和洋女子大学教育振興支援助成中間報告

　本稿は、2020年度から3年計画で進めている児童福祉コースの取り組みについての経過報告である。設置4年目を迎えた児童福祉コースは、保育・福祉・家政の専門性をそなえた保育士養成を一貫して目指してきた。本研究は、地域の未就学児・保護者たちと学生とが交流する場を設定・実践し、その成果と課題を検証するものである。その目的として、以下の２つがあげられる。　１つ目は、和洋女子大学を拠点とした未就学児と保護者たちの交流の場を形成するための介入について探る。２つ目は、地域の親子との交流活動が、保育士の学びにどのように影響するかを探る。　主に7・8 月に実施した交流イベントについて、保護者アンケートと学生の振り返りをまとめる。これによって、地域社会への貢献を目指すとともに、保育士養成における有意義な取り組みとはどのようなものがあるのかを考えていく

The Constrained Maximal Expression Level Owing to Haploidy Shapes Gene Content on the Mammalian X Chromosome.

X chromosomes are unusual in many regards, not least of which is their nonrandom gene content. The causes of this bias are commonly discussed in the context of sexual antagonism and the avoidance of activity in the male germline. Here, we examine the notion that, at least in some taxa, functionally biased gene content may more profoundly be shaped by limits imposed on gene expression owing to haploid expression of the X chromosome. Notably, if the X, as in primates, is transcribed at rates comparable to the ancestral rate (per promoter) prior to the X chromosome formation, then the X is not a tolerable environment for genes with very high maximal net levels of expression, owing to transcriptional traffic jams. We test this hypothesis using The Encyclopedia of DNA Elements (ENCODE) and data from the Functional Annotation of the Mammalian Genome (FANTOM5) project. As predicted, the maximal expression of human X-linked genes is much lower than that of genes on autosomes: on average, maximal expression is three times lower on the X chromosome than on autosomes. Similarly, autosome-to-X retroposition events are associated with lower maximal expression of retrogenes on the X than seen for X-to-autosome retrogenes on autosomes. Also as expected, X-linked genes have a lesser degree of increase in gene expression than autosomal ones (compared to the human/Chimpanzee common ancestor) if highly expressed, but not if lowly expressed. The traffic jam model also explains the known lower breadth of expression for genes on the X (and the Z of birds), as genes with broad expression are, on average, those with high maximal expression. As then further predicted, highly expressed tissue-specific genes are also rare on the X and broadly expressed genes on the X tend to be lowly expressed, both indicating that the trend is shaped by the maximal expression level not the breadth of expression per se. Importantly, a limit to the maximal expression level explains biased tissue of expression profiles of X-linked genes. Tissues whose tissue-specific genes are very highly expressed (e.g., secretory tissues, tissues abundant in structural proteins) are also tissues in which gene expression is relatively rare on the X chromosome. These trends cannot be fully accounted for in terms of alternative models of biased expression. In conclusion, the notion that it is hard for genes on the Therian X to be highly expressed, owing to transcriptional traffic jams, provides a simple yet robustly supported rationale of many peculiar features of X's gene content, gene expression, and evolution