¿Igualdad para las personas en situación de discapacidad? Una reflexión crítica ante el nuevo escenario jurídico de la Ley 1996 de 2019

En este trabajo de investigación se pretende abordar de forma crítica la Ley 1996 de 2019. Partiendo de los diferentes modelos de tratamiento de la discapacidad a nivel internacional, se busca identificar los fundamentos teóricos en que se basa el nuevo escenario de igualdad y autodeterminación de las personas en situación de discapacidad; de este modo, se analizará la finalidad del legislador colombiano al promulgar la Ley mencionada y los retos que tiene el país, el aparato judicial, y los particulares, en la aplicación de esta nueva norma en materia civil y de familia. Más allá de la identificación mencionada, la idea central que se desarrolla en este trabajo de investigación, es que dichos fundamentos (que han sido tendencia en las regulaciones normativas a nivel internacional y que han sido adoptadas de tal forma en el ordenamiento jurídico colombiano por medio de la Ley 1996 de 2019), demuestran, por un lado, el gran avance de Colombia en el respeto hacia la autodeterminación de las personas en situación de discapacidad; pero, por otro lado, parecen también implicar un retroceso en la búsqueda de garantías para estas personas. Así, se señalarán los vacíos procesales y prácticos de esta Ley y se analizará la pertinencia de las nuevas figuras jurídicas de acuerdo con el fin que pretende alcanzar el ordenamiento jurídico colombiano con su promulgación. Todo esto, con la finalidad de construir no solo una reflexión crítica del tema, sino también formular conclusiones referidas a un mejor entendimiento del concepto de discapacidad que permita la adecuada creación de disposiciones normativas en pro de los derechos fundamentales de esta población, de cara a los fines propios de un Estado Social de Derecho

Influence of the cooking process and storage temperature on physicochemical, microbiological and sensorial characteristics of sliced ham

ABSTRACT: Both, cooking and storage, can affect processed meat traits. In this study, six treatments were evaluated: three internal cooking temperatures (72, 75, 78 °C) and two storage temperatures (4 and 8 °C). Mesophilic counts, lactic acid bacteria and color differed (p‹0.001). The product heated to 75 °C, 5 minutes of retention, and stored at 4 °C (75 °C - 5 min - 4 °C) was the most stable. Regarding the content of volatile nitrogen bases, none of the treatments reached degradation levels above the established by technical regulations. As the storage time increased, hardness and instrumental adhesiveness also tended to increase, with the 75 °C – 5 min – 4 °C treatment resulting in the highest hardness value. For all the treatments, pH diminished and syneresis increased as the storage time increased.RESUMEN: El presente trabajo de investigación tiene como objetivo identificar la influencia del proceso de cocción y la temperatura de almacenamiento sobre la vida útil del jamón de cerdo, tajado y empacado. Se realizaron seis tratamientos, con tres temperaturas internas de cocción (72, 75, 78 °C) y dos temperaturas de almacenamiento (4 y 8 °C). Se elaboró un patrón absoluto cocido hasta una temperatura interna de 72 °C, sin tiempo de retención, con una vida útil establecida previamente de 26 días y un patrón relativo, elaborado bajo las mismas condiciones del patrón absoluto, almacenado a 0 °C. El estudio mostró que los recuentos de mesófilos, bacterias ácido lácticas y color, presentaron diferencia significativa (p‹0.001), siendo el más estable el producto calentado hasta 75 °C, 5 minutos de retención y almacenamiento a 4 °C (75 °C - 5min - 4 °C). Respecto al contenido de bases volátiles nitrogenadas se encontró que ninguno de los tratamientos alcanzó niveles de degradación superiores a los establecidos por los reglamentos técnicos. Al incrementarse el periodo de almacenamiento, la dureza y la adhesividad instrumental presentaron tendencia al aumento, siendo el tratamiento 75 °C-5min-4 °C el que reportó mayor valor de dureza. Para todos los tratamientos se encontró que el pH disminuye y la sinéresis aumenta a medida que transcurre el periodo de almacenamiento

Nitrogen levels and their fractioning in gladiolus cultivation for Ferralitic Red soils

The objective of this study was to evaluate growing nitrogen levels and application time of the nitrogen fertilizer in gladiolus cultivation. The experiment was carried out at Instituto de Investigaciones Hortículas Liliana Dimitrova (in the Municipality of Quivicán, La Habana, Cuba) in an Oxisol soil, from October to February of the 2004–2005 and 2005–2006 crop seasons. The quality components of the spikes and plant material were evaluated, as well as the effect of the treatments on the plant nutritional state and the shelf life of the spikes. No differences between nitrogen doses and fertilizer application time in quality variables of spikes and corms were observed. Nevertheless, with the variant 70 kg ha-1 of N, one half applied in plantation and the other half applied 60 days later, a higher spike percentage of commercial categories and a lesser number of stems of inferior quality were obtained. As for the plantation nutritional state, there is a positive relation between the applied nitrogen levels and the foliar content of this element.El objetivo del presente estudio fue evaluar niveles crecientes de nitrógeno y momentos de aplicación del fertilizante nitrogenado en el cultivo del gladiolo. La experiencia se desarrolló en el Instituto de Investigaciones Hortícolas Liliana Dimitrova (Municipio de Quivicán, La Habana, Cuba), en un suelo Ferralítico Rojo, entre los meses de octubre y febrero de las campañas 2004/2005 y 2005/2006. Se evaluaron los componentes de la calidad de las espigas y del material de plantación, así como el efecto de los tratamientos en el estado nutricional de la planta y en la vida en anaquel de las espigas. No se observaron diferencias entre las dosis de nitrógeno y los momentos de aplicación del fertilizante en las variables de calidad de la espiga y del cormo. No obstante, con la variante 70 kg ha-1 de N, aplicada ½ en plantación y ½ a los 60 días posteriores, se logra un mayor porcentaje de espigas ubicadas en las categorías comerciales y un menor número de tallos florales de calidad inferior. En cuanto al estado nutricional de la plantación, existe una relación positiva entre los niveles y los contenidos foliares de nitrógeno aplicados.The objective of this study was to evaluate growing nitrogen levels and application time of the nitrogen fertilizer in gladiolus cultivation. The experiment was carried out at Instituto de Investigaciones Hortículas Liliana Dimitrova (in the Municipality of Quivicán, La Habana, Cuba) in an Oxisol soil, from October to February of the 2004–2005 and 2005–2006 crop seasons. The quality components of the spikes and plant material were evaluated, as well as the effect of the treatments on the plant nutritional state and the shelf life of the spikes. No differences between nitrogen doses and fertilizer application time in quality variables of spikes and corms were observed. Nevertheless, with the variant 70 kg ha-1 of N, one half applied in plantation and the other half applied 60 days later, a higher spike percentage of commercial categories and a lesser number of stems of inferior quality were obtained. As for the plantation nutritional state, there is a positive relation between the applied nitrogen levels and the foliar content of this element

Bacterial antigen translocation and age as BMI-independent contributing factors on systemic inflammation in NAFLD patients

Background & Aims Low‐grade systemic inflammation is a crucial landmark in NAFLD favouring disease progression and comorbidities. We evaluated the input of circulating bacterial antigens on systemic markers of inflammation in NAFLD patients. Patients & Methods Multicenter cross‐sectional study including consecutive patients with biopsy‐proven NAFLD. Demographic, metabolic and fibrosis‐related variables were collected. Circulating bacterial antigens were quantified in blood. Toll‐like receptor SNPs were genotyped. Serum cytokine levels were evaluated. Peripheral blood mononuclear cell response to bacterial antigens was evaluated in vitro. Results Three hundred and fifteen patients from five Spanish hospitals were distributed by BMI. At least, one bacterial antigenic type was found in 66 patients with BMI 30 (77.3%) (P = .014). HOMA‐IR was significantly higher in the presence of circulating antigens among patients with BMI < 30. NASH and significant fibrosis in non‐obese patients were more frequent in the presence of at least two circulating antigenic types. Allelic frequencies of TLR variants were similar to controls and did not affect clinical or laboratory parameters. Pro‐inflammatory cytokines were significantly increased in patients with bacterial antigens, regardless of BMI. TLR gene and protein expression levels were significantly increased in PBMCs from patients with bacterial antigens. Antigen concentrations independently influenced TNF‐α and IL‐6, in both BMI subgroups of patients. Age independently influenced TNF‐α and IL‐6 in non‐obese patients, and TNF‐α in obese patients. Conclusion Serum circulating bacterial antigens as well as age were BMI‐independent factors related to increased systemic inflammation in NAFLD and provides insight on the multifaceted sources of inflammation in these patients.This work has been funded by grants PI16/0967 and PI17/0535 from Instituto de Salud Carlos III, Madrid, Spain, and PROMETEO 2016/001 from Generalitat Valenciana, Valencia, Spain. IGH was recipient of a Young Investigator Grant by CIBERehd, Instituto de Salud Carlos III, Madrid, Spain

Galaxy clusters and groups in the ALHAMBRA Survey

We present a catalogue of 348 galaxy clusters and groups with $0.2<z<1.2$ selected in the 2.78 $deg^2$ ALHAMBRA Survey. The high precision of our photometric redshifts, close to $1\%$, and the wide spread of the seven ALHAMBRA pointings ensure that this catalogue has better mass sensitivity and is less affected by cosmic variance than comparable samples. The detection has been carried out with the Bayesian Cluster Finder (BCF), whose performance has been checked in ALHAMBRA-like light-cone mock catalogues. Great care has been taken to ensure that the observable properties of the mocks photometry accurately correspond to those of real catalogues. From our simulations, we expect to detect galaxy clusters and groups with both $70\%$ completeness and purity down to dark matter halo masses of $M_h\sim3\times10^{13}\rm M_{\odot}$ for $z<0.85$. Cluster redshifts are expected to be recovered with $\sim0.6\%$ precision for $z<1$. We also expect to measure cluster masses with $\sigma_{M_h|M^*_{CL}}\sim0.25-0.35\, dex$ precision down to $\sim3\times10^{13}\rm M_{\odot}$, masses which are $50\%$ smaller than those reached by similar work. We have compared these detections with previous optical, spectroscopic and X-rays work, finding an excellent agreement with the rates reported from the simulations. We have also explored the overall properties of these detections such as the presence of a colour-magnitude relation, the evolution of the photometric blue fraction and the clustering of these sources in the different ALHAMBRA fields. Despite the small numbers, we observe tentative evidence that, for a fixed stellar mass, the environment is playing a crucial role at lower redshifts (z$<$0.5).Comment: Accepted for publication in MNRAS. Catalogues and figures available online and under the following link: http://bascaso.net46.net/ALHAMBRA_clusters.htm

New Care Models for Transgender People in the Spanish Health System: Demands, Controversies and Reflections

[Resumen] La atención sanitaria a las personas transgénero en España se ha establecido de manera progresiva desde 1999, año en que Andalucía crea la primera unidad multidisciplinar para el tratamiento integral de la reasignación de sexo. Este documento analiza los cambios sociales, las demandas y debates entre usuarios y profesionales y los nuevos modelos de atención sanitaria, y también plantea reflexiones sobre la situación actual. La apertura social en España en la concepción de la diversidad sexual y de género es bastante favorable. Las demandas de los usuarios no son uniformes y no siempre coinciden con los criterios de los profesionales. En algunas comunidades autónomas la asistencia sanitaria se está distanciando del modelo recomendado internacionalmente, que basa la atención en equipos especializados o Unidades de Identidad de Género (UIG). Estos nuevos modelos centran la asistencia en la Atención Primaria, además de en endocrinólogos y pediatras de área sin una evaluación coordinada con Salud Mental. Los principales factores contribuyentes al cambio reciente han sido las demandas desde algunas asociaciones de “despatologización” y “descentralización”. Estos nuevos modelos centran la asistencia en la Atención Primaria, además de en endocrinólogos y pediatras de área sin una evaluación coordinada con Salud Mental. Los profesionales que integran las unidades de género, si bien reconocen la necesidad de una visión amplia de la realidad transgénero, alertan del riesgo que supone tratar a personas trans sin una colaboración de especialistas en Salud Mental o por profesionales de área con escasa experiencia. Además, anticipan que la descentralización no facilita el estudio de grandes cohortes, dificultando el avance del conocimiento y la evaluación contrastada con países del entorno. En resumen, los nuevos modelos sanitarios, aunque ofrecen la atención en proximidad, no garantizan mejoras en la calidad ni promueven el análisis comparado de los resultados.[Abstract] Health care for transgender people in Spain has been progressively established since 1999 when the first multidisciplinary unit for the treatment of sex reassignment was created in Andalusia. In this document, the social changes, the demands and debates of users and professionals, the new models of health care for trans people, and reflections on the current situation, have been analysed. The social openness in Spain regarding sexual and gender diversity has evolved quite positively. The health demands of the transgender users are not uniform and do not always match with the criteria of the professionals. In some Spanish regions, health care is distancing itself from the internationally recommended multidisciplinary model. The new healthcare models have been established under the aegis of primary care and/or endocrinologist in the area, without a required psychological assessment. The main contributing factors for this change of model have been the pressure from some associations with demands for "depathologization" and "decentralization". The professionals of gender units, while recognizing the need for a broader vision of trans reality, warn of the risk of treating trans people without the involvement of mental health specialists or by professionals in proximity with little experience. Moreover, the decentralization would not allow acting on large cohorts, which hinders the advance of knowledge and contrasted evaluations with neighbouring countries. In summary, the new health models, although intended to facilitate care through proximity, do not guarantee improvements in quality and difficult to make a comparative evaluation of the results

Familial component of early-onset colorectal cancer: opportunity for prevention

[Background]: Individuals with a non-syndromic family history of colorectal cancer are known to have an increased risk. There is an opportunity to prevent early-onset colorectal cancer (age less than 50 years) (EOCRC) in this population. The aim was to explore the proportion of EOCRC that is preventable due to family history of colorectal cancer. [Methods]: This was a retrospective multicentre European study of patients with non-hereditary EOCRC. The impact of the European Society of Gastrointestinal Endoscopy (ESGE), U.S. Multi-Society Task Force (USMSTF), and National Comprehensive Cancer Network (NCCN) guidelines on prevention and early diagnosis was compared. Colorectal cancer was defined as potentially preventable if surveillance colonoscopy would have been performed at least 5 years before the age of diagnosis of colorectal cancer, and diagnosed early if colonoscopy was undertaken between 1 and 4 years before the diagnosis. [Results]: Some 903 patients with EOCRC were included. Criteria for familial colorectal cancer risk in ESGE, USMSTF, and NCCN guidelines were met in 6.3, 9.4, and 30.4 per cent of patients respectively. Based on ESGE, USMSTF, and NCCN guidelines, colorectal cancer could potentially have been prevented in 41, 55, and 30.3 per cent of patients, and diagnosed earlier in 11, 14, and 21.1 per cent respectively. In ESGE guidelines, if surveillance had started 10 years before the youngest relative, there would be a significant increase in prevention (41 versus 55 per cent; P = 0.010). [Conclusion]: ESGE, USMSTF, and NCCN criteria for familial colorectal cancer were met in 6.3, 9.4, and 30.4 per cent of patients with EOCRC respectively. In these patients, early detection and/or prevention could be achieved in 52, 70, and 51.4 per cent respectively. Early and accurate identification of familial colorectal cancer risk and increase in the uptake of early colonoscopy are key to decreasing familial EOCRC.This study was funded by Instituto de Salud Carlos III through project PI20/0974 to J.P and PI19/01867 to F.B. (co-funded by European Regional Development Fund ‘A way to make Europe’); and Agència de Gestió d’Ajuts Universitaris i de Recerca (Generalitat de Catalunya, GRC 2017SGR653). Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas is funded by the Instituto de Salud Carlos III

Violencias basadas en género: la otra tragedia de Colombia

This book, a product of academic and discursive activity, develops five chapters of scientific dissemination in which it presents an interdisciplinary analysis of the phenomena that extend in gender violence against women. The first chapter deals with the factual circumstances for the imputation of femicide in Colombia; the second chapter constructs a clinical psychological approach to the aggressor; the third chapter establishes an analysis of femicide from the logics of evolutionary and developmental psychology; the fourth chapter refers to the warp and woof of the brand of violence against women; the fifth chapter analyzes the cultural, social and educational elements of hegemonic machismo as a precipitating, maintaining and creating factor of violence against women. This publication seeks to contribute to the social, academic and scientific expansion of gender-based violence as another of Colombia's most atrocious tragedies that require a refined view on the part of divergent and critically grounded thinking.PublishedEste libro, producto de la actividad académica y discursiva, desarrolla cinco capítulos de divulgación científica en los cuales presenta un análisis interdisciplinario de los fenómenos que se extienden en las violencias basadas en género en contra de la mujer. El primer capítulo trabaja las circunstancias fácticas para la imputación del feminicidio en Colombia; el segundo construye una aproximación clínica psicológica del feminicida, el tercero establece un análisis del feminicidio desde las lógicas de la psicología evolutiva y del desarrollo, el cuarto refiere las urdimbres a propósito de la marca de violencia en contra de la mujer; el quinto capítulo analiza los elementos culturales, sociales y educativos del machismo hegemónico como factor precipitador, mantenedor y creador de las violencias en contra de la mujer. Con esta publicación se busca contribuir a la expansión social, académica y científica de las violencias basadas en género como otra de las tragedias más atroces de Colombia que requieren de miradas afinadas por parte del pensamiento divergente y crítico fundamentado

The ALHAMBRA survey: Estimation of the clustering signal encoded in the cosmic variance

[Aims]: The relative cosmic variance (σv) is a fundamental source of uncertainty in pencil-beam surveys and, as a particular case of count-in-cell statistics, can be used to estimate the bias between galaxies and their underlying dark-matter distribution. Our goal is to test the significance of the clustering information encoded in the σv measured in the ALHAMBRA survey. [Methods]: We measure the cosmic variance of several galaxy populations selected with B-band luminosity at 0.35 ≤ z< 1.05 as the intrinsic dispersion in the number density distribution derived from the 48 ALHAMBRA subfields. We compare the observational σv with the cosmic variance of the dark matter expected from the theory, σv,dm. This provides an estimation of the galaxy bias b. [Results]: The galaxy bias from the cosmic variance is in excellent agreement with the bias estimated by two-point correlation function analysis in ALHAMBRA. This holds for different redshift bins, for red and blue subsamples, and for several B-band luminosity selections. We find that b increases with the B-band luminosity and the redshift, as expected from previous work. Moreover, red galaxies have a larger bias than blue galaxies, with a relative bias of brel = 1.4 ± 0.2. [Conclusions]: Our results demonstrate that the cosmic variance measured in ALHAMBRA is due to the clustering of galaxies and can be used to characterise the σv affecting pencil-beam surveys. In addition, it can also be used to estimate the galaxy bias b from a method independent of correlation functions.This work has been mainly funded by the FITE (Fondos de Inversiones de Teruel) and the projects AYA2012-30789, AYA2006-14056, and CSD2007-00060. We also acknowledge support from the Spanish Ministry for Economy and Competitiveness and FEDER funds through grants AYA2010-15081, AYA2010-15169, AYA2010-22111-C03-01, AYA2010-22111-C03-02, AYA2011-29517-C03-01, AYA2012-39620, AYA2013-40611-P, AYA2013-42227-P, AYA2013-43188-P, AYA2013-48623-C2-1, AYA2013-48623-C2-2, ESP2013-48274, AYA2014-58861-C3-1, Aragon Government Research Group E103, Generalitat Valenciana projects Prometeo 2009/064 and PROMETEOII/2014/060, Junta de Andalucia grants TIC114, JA2828, P10-FQM-6444, and Generalitat de Catalunya project SGR-1398. A.J.C. and C.H.-M. are Ramon y Cajal fellows of the Spanish government. A. M. acknowledges the financial support of the Brazilian funding agency FAPESP (Post-doc fellowship - process number 2014/11806-9). M.P. acknowledges financial support from JAE-Doc program of the Spanish National Research Council (CSIC), co-funded by the European Social Fund.Peer Reviewe