Beyond the risks to food availability – linking climatic hazard vulnerability with the food access of delta-dwelling households

Although climate-driven hazards have been widely implicated as a key threat to food security in the delta regions of the developing world, the empirical basis of this assertion has centred predominantly on the food availability dimension of food security. Little is known if climatic hazards could affect the food access of delta-resident households and who is likely to be at risk and why. We explored these questions by using the data from a sample of households resident within the Ganges-Brahmaputra-Meghna (GBM) delta in Bangladesh. We used an index-based analytical approach by drawing on the vulnerability and food security literature. We computed separate vulnerability indices for flood, cyclone, and riverbank erosion and assessed their effects on household food access through regression modelling. All three vulnerability types demonstrated significant negative effects on food access; however, only flood vulnerability could significantly reduce a household’s food access below an acceptable threshold. Households that were less dependent on natural resources for their livelihoods – including unskilled day labourers and grocery shop owners – were significantly more likely to have unacceptable level of food access due to floods. Adaptive capacity, measured as a function of household asset endowments, proved more important in explaining food access than the exposure-sensitivity to flood itself. Accordingly, we argue that improving food security in climatic hazard-prone areas of developing country deltas would require moving beyond agriculture or natural resources focus and promoting hazard-specific, all-inclusive and livelihood-focused asset-building interventions. We provide an example of a framework for such interventions and reflect on our analytical approach

May Measurement Month (MMM) 2017: an analysis of blood pressure screening results in Bangladesh-South Asia

Elevated blood pressure (BP) is a growing burden worldwide, leading to over 10 million deaths each year. Based on the findings of the non-communicable disease Risk Factors Survey Bangladesh 2010, the prevalence of hypertension in adults 25 years or older in Bangladesh is 20.1%. The Bangladesh Demographic Health Survey, 2011 showed that approximately 50% of those affected are unaware of their hypertensive condition. The May Measurement Month 2017 (MMM17) is a global initiative of the International Society of Hypertension (ISH) aimed at raising awareness of high BP. We participated in MMM17 to raise awareness of hypertension screening and identify those with elevated BP who were unaware, and those on treatment with still uncontrolled hypertension. Following the standard protocol designed by the ISH, we participated in MMM17, an opportunistic cross-sectional survey of volunteers aged ≥18. It was carried out in May 2017. BP measurement, the definition of hypertension and statistical analysis followed the standard MMM protocol. Data were collected from 35 screening sites in 33 districts in Bangladesh. Personnel from several government and non-government organizations volunteered in this huge event. A total of 11 418 individuals were screened during MMM17, of which 5401 (47.3%) were found to have hypertension. Of 8365 individuals not receiving anti-hypertensive medication, 2348 (28.1%) were hypertensive. Of 3053 individuals receiving anti-hypertensive medication, 1594 (52.2%) had uncontrolled BP. MMM17 was the largest BP screening campaign undertaken in Bangladesh. This study suggests that opportunistic screening can identify significant numbers of people with raised BP. A periodic public health programme at a national level needs to be initiated to increase hypertension detection and control rate and thus for the prevention of cardiovascular diseases

Mapping geographical inequalities in access to drinking water and sanitation facilities in low-income and middle-income countries, 2000-17

Background Universal access to safe drinking water and sanitation facilities is an essential human right, recognised in the Sustainable Development Goals as crucial for preventing disease and improving human wellbeing. Comprehensive, high-resolution estimates are important to inform progress towards achieving this goal. We aimed to produce high-resolution geospatial estimates of access to drinking water and sanitation facilities. Methods We used a Bayesian geostatistical model and data from 600 sources across more than 88 low-income and middle-income countries (LMICs) to estimate access to drinking water and sanitation facilities on continuous continent-wide surfaces from 2000 to 2017, and aggregated results to policy-relevant administrative units. We estimated mutually exclusive and collectively exhaustive subcategories of facilities for drinking water (piped water on or off premises, other improved facilities, unimproved, and surface water) and sanitation facilities (septic or sewer sanitation, other improved, unimproved, and open defecation) with use of ordinal regression. We also estimated the number of diarrhoeal deaths in children younger than 5 years attributed to unsafe facilities and estimated deaths that were averted by increased access to safe facilities in 2017, and analysed geographical inequality in access within LMICs. Findings Across LMICs, access to both piped water and improved water overall increased between 2000 and 2017, with progress varying spatially. For piped water, the safest water facility type, access increased from 40.0% (95% uncertainty interval [UI] 39.4-40.7) to 50.3% (50.0-50.5), but was lowest in sub-Saharan Africa, where access to piped water was mostly concentrated in urban centres. Access to both sewer or septic sanitation and improved sanitation overall also increased across all LMICs during the study period. For sewer or septic sanitation, access was 46.3% (95% UI 46.1-46.5) in 2017, compared with 28.7% (28.5-29.0) in 2000. Although some units improved access to the safest drinking water or sanitation facilities since 2000, a large absolute number of people continued to not have access in several units with high access to such facilities (>80%) in 2017. More than 253 000 people did not have access to sewer or septic sanitation facilities in the city of Harare, Zimbabwe, despite 88.6% (95% UI 87.2-89.7) access overall. Many units were able to transition from the least safe facilities in 2000 to safe facilities by 2017; for units in which populations primarily practised open defecation in 2000, 686 (95% UI 664-711) of the 1830 (1797-1863) units transitioned to the use of improved sanitation. Geographical disparities in access to improved water across units decreased in 76.1% (95% UI 71.6-80.7) of countries from 2000 to 2017, and in 53.9% (50.6-59.6) of countries for access to improved sanitation, but remained evident subnationally in most countries in 2017. Interpretation Our estimates, combined with geospatial trends in diarrhoeal burden, identify where efforts to increase access to safe drinking water and sanitation facilities are most needed. By highlighting areas with successful approaches or in need of targeted interventions, our estimates can enable precision public health to effectively progress towards universal access to safe water and sanitation. Copyright (C) 2020 The Author(s). Published by Elsevier Ltd.Peer reviewe

Determination of yield loss and Economic Threshold Density of Scirpus maritimus in Winter Rice

ABSTRACT Rice is the staple food in Bangladesh. Scirpus maritimus infests rice heavily, causing enormous yield losses and threatening in the sustainability of the rice production system. Information on the interference and economic threshold (ET) of S. maritimus will be useful for the effective management of S. maritimus in rice. This will lead to the rationalization of herbicide use and the reduction of herbicide input into the environment. In this study, it was observed that the weed infestation levels of 80 or more S. maritimus plants per m 2 offered higher competition, leading to significant reductions in the growth (dry weight, height, crop growth rate, net assimilation rate and leaf area index) and yield of rice. The regression model was effective in simulating yield losses in relation to a wide range of S. maritimus dry matter. The weed dry matter-crop yield model was found to be effective in simulating rice yield losses in relation to a wide range of S. maritimus dry matter. The ET dry matter of S. maritimus were 18.39, 15.61 and 13.57g/m 2 (4, 3 and 3 S. maritimus number m -2 , respectively) in first year at the 70, 80, and 90% control efficiencies, respectively, of the herbicide, Bensulfuronmethyl + Pretilachlor 6.6% GR. In the second year, the ET dry matter of S. maritimus were 15.06, 12.38 and 10.51 g/m 2 (3, 3 and 2 S. maritimus number m -2 , respectively) at the 70, 80, and 90% control efficiencies, respectively, of the herbicide. In rice cultivation, 10 to 18 g S. maritimus per m 2 (2 to 4 number m -2 ) could be allowed without economic yield loss

Response of Nerica Rice to Nitrogen Fertilization

An experiment was conducted during T. Aman season, 2014 at the Agronomy Research Field, Bangladesh Rice Research Institute, Gazipur to determine the optimum rate of nitrogen fertilizer for higher yield in nerica rice. The experiment comprised of three rice varieties viz. NERICA1, NERICA10 and BRRI dhan57; and five nitrogen levels viz. 0, 23, 46, 69 and 92 kg ha-1. The rice var. BRRI dhan57 with 69 and 92 kg N ha-1 produced significantly identical with higher panicles m-2. But NERICA1 and NERICA10 produced higher number of panicles with 46 and 69 kg N ha-1, respectively. However, BRRI dhan57 with 46 kg N ha-1 produced highest grains panicle-1 but NERICA1 and NERICA10 produced higher number of grains panicle-1 with 23 kg N ha-1. The highest percentage of sterility was recorded in NERICA10 with 69 kg N ha-1. The regression analysis gave the optimum dose of nitrogen for NERICA1, NERICA10 and BRRI dhan57 which were 69.25, 74.25 and 85.75 kg N ha-1, respectively

Assessment of Soil Chemical Properties and Rice Yield in Tidal Submergence Ecosystem

Spatial variability of soil chemical properties is critical for improving rice productivity and sustainable farming techniques. However, a systematic assessment on the spatial variability of tidal ecosystem has not been conducted. So, 144 soil samples were collected across Barisal, Borguna and Jalkhati districts and analyzed for six common chemical properties. Rice yield data was obtained by surveying farmers during crop harvest. Soil parameters and rice yield varied considerably throughout the study areas and their coefficients of variation ranged from 8.77 to 71.04%. Slight variability was observed for soil organic matter (SOM) and available K. The pH of the soils was slightly acidic to alkaline. These paddy fields were characterized by high concentrations of SOM, available P, K and S; but low total N. Rice yield was significantly and positively correlated with pH, available K and S, but negatively correlated with SOM

Performance of sustainable green concrete incorporated with fly ash, rice husk ash, and stone dust

The performance of a sustainable green concrete with fly ash (FA), rice husk ash (RHA), and stone dust (SD) as a partial replacement of cement and sand was experimentally explored. FA and RHA have a high silica content, are highly pozzolanic in nature and have a high surface area without any treatment. These by-products show filler effects, which enhance concrete’s density. Results showed that the FA and RHA materials have good hydration behaviour and effectively develop strength at an early age of concrete. SD acts as a stress transferring medium within concrete, thereby allowing the concrete to be stronger in compression, and bending. Consequently, water absorption capacity of the sustainable concrete was lower than that of the ordinary one. However, a little reduction in strength was observed after the replacement of the binder and aggregate using the FA, RHA and SD, but the reduction was insignificant. The reinforced structure with sustainable concrete containing the FA, RHA, and SD generally fails in concrete crushing tests initiated by flexural cracking followed by shear cracks. The sustainable concrete could be categorized as a perfect material with no significant conciliation in strength properties and can be applied to design under-reinforced elements for a low-to-moderate service load

Discovery of neddylation E2s inhibitors with therapeutic activity

Abstract Neddylation is the writing of monomers or polymers of neural precursor cells expressed developmentally down-regulated 8 (NEDD8) to substrate. For neddylation to occur, three enzymes are required: activators (E1), conjugators (E2), and ligators (E3). However, the central role is played by the ubiquitin-conjugating enzymes E2M (UBE2M) and E2F (UBE2F), which are part of the E2 enzyme family. Recent understanding of the structure and mechanism of these two proteins provides insight into their physiological effects on apoptosis, cell cycle arrest and genome stability. To treat cancer, it is therefore appealing to develop novel inhibitors against UBE2M or UBE2F interactions with either E1 or E3. In this evaluation, we summarized the existing understanding of E2 interaction with E1 and E3 and reviewed the prospective of using neddylation E2 as a pharmacological target for evolving new anti-cancer remedies