High-field Hall resistivity and magnetoresistance in electron-doped Pr_2-xCe_xCuO_{4-\delta}

We report resistivity and Hall effect measurements in electron-doped Pr$_{2-x}$Ce$_{x}$CuO$_{4-\delta}$ films in magnetic field up to 58 T. In contrast to hole-doped cuprates, we find a surprising non-linear magnetic field dependence of Hall resistivity at high field in the optimally doped and overdoped films. We also observe a crossover from quadratic to linear field dependence of the positive magnetoresistance in the overdoped films. A spin density wave induced Fermi surface reconstruction model can be used to qualitatively explain both the Hall effect and magnetoresistance.Comment: PRL in pres

Evidence for a quantum phase transition in the electron-doped cuprate Pr2-xCexCuO4+d from Hall and resistivity measurements

The doping and temperature dependence of the Hall coefficient, RH, and ab-plane resistivity in the normal state down to 350mK is reported for oriented films of the electron-doped high-Tc superconductor Pr2-xCexCuO4+d. The doping dependence of b (r=r0+AT^b) and R_sub_H (at 350 mK) suggest a quantum phase transition at a critical doping near x=0.165.Comment: 11 pages 4 figures Phys. Rev. Lett. 92, 167001 (2004

A Model for the Schottky Anomaly in Metallic Nd2−yCeyCuO4Nd_{2-y}Ce_{y}CuO_{4}

We present a simple model for the doped compound $Nd_{2-y}Ce_{y}CuO_{4}$, in order to explain some recent experimental results on the latter. Within a Hartree-Fock context, we start from an impurity Anderson-like model and consider the magnetic splitting of the $Nd$-$4f$ ground state Kramers doublet due to exchange interactions with the ordered $Cu$ moments. Our results are in very good agreement with the experimental data, yielding a Schottky anomaly peak for the specific heat that reduces its amplitude, broadens and shifts to lower temperatures, upon $Ce$ doping. For overdoped compounds at low temperatures, the specific heat behaves linearly and the magnetic susceptibility is constant. A smooth transition from this Fermi liquid like behavior ocurrs as temperature is increased and at high temperatures the susceptibility exhibits a Curie-like behavior. Finally, we discuss some improvements our model is amenable to incorporate.Comment: 7 pages, 5 figures, and 13 reference

Temperature dependence of the spectral weight in p- and n-type cuprates: a study of normal state partial gaps and electronic kinetic energy

The optical conductivity of CuO2 (copper-oxygen) planes in p- and n-type cuprates thin films at various doping levels is deduced from highly accurate reflectivity data. The temperature dependence of the real part sigma1(omega) of this optical conductivity and the corresponding spectral weight allow to track the opening of a partial gap in the normal state of n-type Pr{2-x}Ce(x)CuO4 (PCCO), but not of p-type Bi2Sr2CaCu2O(8+delta} (BSCCO) cuprates. This is a clear difference between these two families of cuprates, which we briefly discuss. In BSCCO, the change of the electronic kinetic energy Ekin - deduced from the spectral weight- at the superconducting transition is found to cross over from a conventional BCS behavior (increase of Ekin below Tc to an unconventional behavior (decrease of Ekin below Tc) as the free carrier density decreases. This behavior appears to be linked to the energy scale over which spectral weight is lost and goes into the superfluid condensate, hence may be related to Mott physics

Liquid-crystalline phase transitions in lipid droplets are related to cellular states and specific organelle association.

Lipid droplets (LDs) are ubiquitous organelles comprising a central hub for cellular lipid metabolism and trafficking. This role is tightly associated with their interactions with several cellular organelles. Here, we provide a systematic and quantitative structural description of LDs in their native state in HeLa cells enabled by cellular cryoelectron microscopy. LDs consist of a hydrophobic neutral lipid mixture of triacylglycerols (TAG) and cholesteryl esters (CE), surrounded by a single monolayer of phospholipids. We show that under normal culture conditions, LDs are amorphous and that they transition into a smectic liquid-crystalline phase surrounding an amorphous core at physiological temperature under certain cell-cycle stages or metabolic scenarios. Following determination of the crystal lattice spacing of 3.5 nm and of a phase transition temperature below 43 degrees C, we attributed the liquid-crystalline phase to CE. We suggest that under mitotic arrest and starvation, relative CE levels increase, presumably due to the consumption of TAG metabolites for membrane synthesis and mitochondrial respiration, respectively, supported by direct visualization of LD-mitochondrial membrane contact sites. We hypothesize that the structural phase transition may have a major impact on the accessibility of lipids in LDs to enzymes or lipid transporters. These may become restricted in the smectic phase, affecting the exchange rate of lipids with surrounding membranes and lead to a different surface occupancy of LD-associated proteins. Therefore, the composition and the resulting internal structure of LDs is expected to play a key role in their function as hubs of cellular lipid flux

IDENTIFIKASI PERMASALAHAN DAN STRATEGI PENGELOLAAN TAMAN HUTAN RAYA NURAKSA

Tahura is a nature conservation area with a purpose to collecting natural or non-native plants and or animals, native and or non-native species, which are utilized for research, science, education, supporting cultivation, culture, tourism and recreation. As a conservation area whose territory is directly adjacent to the community, Nuraksa Forest Park is a source of economy and life for the surrounding community so that it can be said that there is community dependence on land in the area. This is a challenge in managing the area. In an effort to provide management direction so that the functions and benefits that have been regulated in the legislation and the achievement of the goals that have been formulated can be achieved, the perceived need for activities to identify problems and management strategies of Nuraksa Forest Park. The research was carried out through a series of activities, which consisted of literature studies, interviews and field surveys. The results of the SWOT analysis of the management of Nuraksa Forest Park are in quadrant III. This shows that Nuraksa Forest Park faces enormous opportunities, but on the other hand faces several internal obstacles / weaknesses. The strategy that must be implemented is to minimize the internal problems of the institution so that it can seize better opportunities

STRUKTUR POPULASI BEKANTAN (NASALIS LARVATUS) DI RAWA GELAM

Number of proboscis monkey population in Cajuputi Swamp Forest is 258 individual. This population is strongly influenced by condition of its habitat which is to degradation to 3.417 hektar. The object of research is to analyzed structure of proboscis monkey population. Method of research are river survey (Sha et al, 2008) and concentration count (Anonymous, 1981; Alikodra, 2002). The avarage density of proboscis monkey in their homerange is 3 individuals/hectares, with 30,2% males and 48,5 % females. This population is slow growth because there is only one baby/year, this is also indicated by number of 14 individuals babies (5,4%) and 41 infant (15,9%) lower when compared to number of adult indiviuals, so it is very worryng for continued growth of the population

4D Visualization of replication foci in mammalian cells corresponding to individual replicons

Since the pioneering proposal of the replicon model of DNA replication 50 years ago, the predicted replicons have not been identified and quantified at the cellular level. Here, we combine conventional and super-resolution microscopy of replication sites in live and fixed cells with computational image analysis. We complement these data with genome size measurements, comprehensive analysis of S-phase dynamics and quantification of replication fork speed and replicon size in human and mouse cells. These multidimensional analyses demonstrate that replication foci (RFi) in three-dimensional (3D) preserved somatic mammalian cells can be optically resolved down to single replicons throughout S-phase. This challenges the conventional interpretation of nuclear RFi as replication factories, that is, the complex entities that process multiple clustered replicons. Accordingly, 3D genome organization and duplication can be now followed within the chromatin context at the level of individual replicons

Mechanisms and advancement of antifading agents for fluorescence microscopy and single-molecule spectroscopy

Modern fluorescence microscopy applications go along with increasing demands for the employed fluorescent dyes. In this work, we compared antifading formulae utilizing a recently developed reducing and oxidizing system (ROXS) with commercial antifading agents. To systematically test fluorophore performance in fluorescence imaging of biological samples, we carried out photobleaching experiments using fixed cells labeled with various commonly used organic dyes, such as Alexa 488, Alexa 594, Alexa 647, Cy3B, ATTO 550, and ATTO 647N. Quantitative evaluation of (i) photostability, (ii) brightness, and (iii) storage stability of fluorophores in samples mounted in different antifades (AFs) reveal optimal combinations of dyes and AFs. Based on these results we provide guidance on which AF should preferably be used with a specific dye. Finally, we studied the antifading mechanisms of the commercial AFs using single-molecule spectroscopy and reveal that these empirically selected AFs exhibit similar properties to ROXS AFs

Microwave Electrodynamics of Electron-Doped Cuprate Superconductors

We report microwave cavity perturbation measurements of the temperature dependence of the penetration depth, lambda(T), and conductivity, sigma(T) of Pr_{2-x}Ce_{x}CuO_{4-delta} (PCCO) crystals, as well as parallel-plate resonator measurements of lambda(T) in PCCO thin films. Penetration depth measurements are also presented for a Nd_{2-x}Ce_{x}CuO_{4-delta} (NCCO) crystal. We find that delta-lambda(T) has a power-law behavior for T<T_c/3, and conclude that the electron-doped cuprate superconductors have nodes in the superconducting gap. Furthermore, using the surface impedance, we have derived the real part of the conductivity, sigma_1(T), below T_c and found a behavior similar to that observed in hole-doped cuprates.Comment: 4 pages, 4 figures, 1 table. Submitted to Physical Review Letters revised version: new figures, sample characteristics added to table, general clarification give