11 research outputs found
Mononuclear, homo- and hetero-binuclear complexes of 1-(5-(1-(2-aminophenylimino)ethyl)-2,4-dihydroxyphenyl)ethanone: synthesis, magnetic, spectral, antimicrobial, antioxidant, and antitumor studies
<p>A new Schiff base, H<sub>2</sub>L, was prepared by condensation of 4,6-diacetylresorcinol with <i>o</i>-phenylenediamine in molar ratio 1 : 1. The ligand reacted with copper(II), nickel(II), cobalt(II), iron(III), zinc(II), oxovanadium(IV), and dioxouranium(VI) ions in the absence and presence of LiOH to yield mononuclear and homobinuclear complexes. The mononuclear dioxouranium(VI) complex [(HL)-(UO<sub>2</sub>)(OAc)(H<sub>2</sub>O)]·5H<sub>2</sub>O was used to synthesize heterobinuclear complexes. The ligand and its metal complexes were characterized by elemental analyses, IR, <sup>1</sup>H-, and <sup>13</sup>C-NMR, electronic, ESR and mass spectra, conductivity, and magnetic susceptibility measurements as well as thermal analysis. In the absence of LiOH, mononuclear complexes (<b>1</b>, <b>4</b>, and <b>9</b>) were obtained; in the presence of LiOH, binuclear complexes (<b>3</b>, <b>5</b>, <b>7</b>, and <b>10</b>) as well as mononuclear complexes (<b>2</b>, <b>6</b>, and <b>8</b>) were obtained. In the mononuclear complexes, the coordinating sites are the phenolic oxygen, azomethine nitrogen, and amino nitrogen. In addition to these coordinating sites, the free carbonyl and phenolic OH are involved in coordination in binuclear complexes. The metal complexes exhibited octahedral, tetrahedral, and square planar geometries while the uranium is seven-coordinate. The antimicrobial and antioxidant activities of the ligand and its complexes were investigated. The ligand and the metal complexes showed antitumor activity against Ehrlich Acites Carcinoma.</p
Mononuclear, homo- and hetero-binuclear complexes of 1-(5-(1-(2-aminophenylimino)ethyl)-2,4-dihydroxyphenyl)ethanone: synthesis, magnetic, spectral, antimicrobial, antioxidant, and antitumor studies
New non-toxic transition metal nanocomplexes and Zn complex-silica xerogel nanohybrid: Synthesis, spectral studies, antibacterial, and antitumor activities
Formation thermodynamic parameters of nano copper (II) acetate monohydrate with 4,6-diacetylresorcinol in mixed solvents
Structural variety in copper(II) complexes of 3-formylchromone: Synthesis, spectral, thermal, molecular modeling and biological studies
Structural variety of mono- and binuclear transition metal complexes of 3-[(2-hydroxy-benzylidene)-hydrazono]-1-(2-hydroxyphenyl)-butan-1-one: Synthesis, spectral, thermal, molecular modeling, antimicrobial and antitumor studies
Oxovanadium(IV), cerium(III), thorium(IV) and dioxouranium(VI) complexes of 1-ethyl-4-hydroxy-3-(nitroacetyl)quinolin-2(1H)-one: Synthesis, spectral, thermal, fluorescence, DFT calculations, antimicrobial and antitumor studies
Coordination behavior of new bis(tridentate ONO, ONS and ONN) donor hydrazones towards some transition metal ions: Synthesis, spectral, thermal, antimicrobial and antitumor studies
Synthesis, spectral studies, and antimicrobial activity of binary and ternary Cu(II), Ni(II), and Fe(III) complexes of new hexadentate Schiff bases derived from 4,6-diacetylresorcinol and amino acids
Synthesis and characterization of N<sub>3</sub>S<sub>2</sub> donors macrocyclic copper(II) complexes. Catechol oxidase and phenoxazinone synthase biomimetic catalytic activity
<p>A new series of copper(II) complexes have been synthesized with macrocyclic ligands L<sup>1</sup> and L<sup>2</sup> having N<sub>3</sub>S<sub>2</sub>-donating atoms in the 12-membered macrocyclic ring. The structure characterization of these newly synthesized copper(II) complexes was achieved by various physicochemical techniques. It has been shown that the stereochemistry of complexes is dependent on the type of counter anions incorporated in the complex molecule. Mimicking copper oxidase enzymes, namely catechol oxidase and phenoxazinone synthase, was investigated and the results obtained demonstrated that there is a correlation between the structural properties of these copper(II) complexes and the oxidase biomimetic catalytic activities. Kinetic measurements revealed second-order dependence on the catalyst concentration for 3,5-DTBCH<sub>2</sub> and first order in the case of OAPH. On the other hand, for the substrate concentration dependence, a saturation-type behavior was detected for both 3,5-DTBCH<sub>2</sub> and OAPH. Addition of Lewis base, triethylamine, in both systems exhibits dramatic effect on the rate of these catalytic aerobic oxidation reactions. The probable mechanistic implications of both catalytic systems are discussed.</p