Planispiral Burrows from a Recent Lacustrine Beach, Gander Lake, Newfoundland

Simple horizontal, planispiral burrows occur in Recent beach sediments on the south shore of Gander Lake, Newfoundland. The burrows apparently represent deposit feeding, possibly by an arthropod. This occurrence extends the known environmental range of such traces into lacustrine settings and illustrates that such behaviour is not exclusive to marine settings

A Midsummer Knot's Dream

In this paper, we introduce playing games on shadows of knots. We demonstrate two novel games, namely, To Knot or Not to Knot and Much Ado about Knotting. We also discuss winning strategies for these games on certain families of knot shadows. Finally, we suggest variations of these games for further study.Comment: 11 pages, 8 figures. To appear, College Mathematics Journal

The 'Rock ‘n’ Fossil Road Show:' An Enduring Earth Science Educational Outreach Initiative in Calgary, Alberta

Since 2004, the Calgary office of the Geological Survey of Canada has been holding ‘Rock ‘n’ Fossil Road Shows’ at Calgary Public Library branches, in partnership with the Alberta Science Network and the Alberta Palaeontological Society. These now-annual earth science education outreach events have given more than 3700 people of all ages the opportunity to view, examine, and learn about GSC-Calgary’s collection of rocks, minerals, and fossils (including many museum quality pieces), have their own samples and collections identified by experts, and gain a better understanding of local and regional geology. This article describes what goes into organizing these events, reviews their evolution, and discusses reasons for their enduring success. The ‘Road Show’ approach can be viable in a range of settings and may be a good educational outreach option for research institutes with collections of interesting geological specimens and a critical mass of interested staff.RÉSUMÉDepuis 2004, le bureau de Calgary de la Commission géologique du Canada tient des représentations de son spectacle itinérant « Roche et fossiles » dans les succursales de la bibliothèque publique de Calgary, en partenariat avec l’Alberta Science Network et l’Alberta Palaeontological Society. Ces activités de rayonnement en sciences de la Terre, maintenant annuels, ont déjà offert à plus de 3700 personnes de tous âges la possibilité de voir, d'examiner et d'apprendre à partir de la collection de roches, de minéraux et de fossiles de la CGC-Calgary (certaines pièces de qualité muséale), et de voir leurs propres échantillons et collections identifiés par des experts, et ainsi obtenir une meilleure compréhension de la géologie locale et régionale. Le présent article décrit les détails de l'organisation de ces événements, retrace leur évolution et revoit les raisons de leur succès durable. L'approche du « spectacle itinérant » peut être viable dans différents contextes et peut être une bonne option de sensibilisation éducative pour les instituts de recherche disposant de collections de spécimens géologiques intéressants et d’une masse critique d’employés intéressés

Four replies

Illustration not included in Web versio

Empathy and affect: what can empathied bodies do?

While there has been much interest in the apparent benefits of empathy in improving outcomes of medical care, there is continuing concern over the philosophical nature of empathy. We suggest that part of the difficulty in coming to terms with empathy is due to the modernist dichotomies that have structured Western medical discourse, such that doctor and patient, knower and known, cognitive and emotional, subject and object are situated in oppositional terms, with the result that such accounts cannot coherently encompass an emotional doctor, or a patient as knower, or empathy as other than a possession or a trait. This paper explores what, by contrast, a radical critique of the Cartesian world view, in the form of a Deleuzean theoretical framework, would open up in new perspectives on empathy. We extend the framework of emotional geography to ask what happens when people are affected by empathy. We suggest that doctors and patients might be more productively understood as embodied subjects that are configured in their capacities by how they are affected by singular ‘events’ of empathy. We sketch out how the Deleuzean framework would make sense of these contentions and identify some possible implications for medical education and practice. Keywords: Empathy, Medicine, Affect, Philosophy, Subjectivit

Can chemical and molecular biomarkers help discriminate between industrial, rural and urban environments?

Abstract Air samples from four contrasting outdoor environments including a park, an arable farm, a waste water treatment plant and a composting facility were analysed during the summer and winter months. The aim of the research was to study the feasibility of differentiating microbial communities from urban, rural and industrial areas between seasons with chemical and molecular markers such as microbial volatile organic compounds (MVOCs) and phospholipid fatty acids (PLFAs). Air samples (3 l) were collected every 2 h for a total of 6 h in order to assess the temporal variations of MVOCs and PLFAs along the day. MVOCs and VOCs concentrations varied over the day, especially in the composting facility which was the site where more human activities were carried out. At this site, total VOC concentration varied between 80 and 170 μg m−3 in summer and 20–250 μg m−3 in winter. The composition of MVOCs varied between sites due to the different biological substrates including crops, waste water, green waste or grass. MVOCs composition also differed between seasons as in summer they are more likely to get modified by oxidation processes in the atmosphere and in winter by reduction processes. The composition of microbial communities identified by the analysis of PLFAs also varied among the different locations and between seasons. The location with higher concentrations of PLFAs in summer was the farm (7297 ng m−3) and in winter the park (11,724 ng m−3). A specific set of MVOCs and PLFAs that most represent each one of the locations was identified by principal component analyses (PCA) and canonical analyses. Further to this, concentrations of both total VOCs and PLFAs were at least three times higher in winter than in summer. The difference in concentrations between summer and winter suggest that seasonal variations should be considered when assessing the risk of exposure to these compounds

Fingerprinting outdoor air environment using microbial volatile organic compounds (MVOCs) – A review

© 2016 The Authors The impact of bioaerosol emissions from urban, agricultural and industrial environments on local air quality is of growing policy concern. Yet the risk exposure from outdoor emissions is difficult to quantify in real-time as microbial concentration in air is low and varies depending on meteorological factors and land use types. While there is also a large number of sampling methods in use, there is yet no standardised protocol established. In this review, a critical insight into chemical fingerprint analysis of microbial volatile organic compounds (MVOC) is provided. The most suitable techniques for sampling and analysing MVOCs in outdoor environments are reviewed and the need for further studies on MVOCs from outdoor environments including background levels is highlighted. There is yet no rapid and portable technique that allows rapid detection and analysis of MVOCs on site. Further directions towards a portable GC–MS coupled with SPME or an electronic nose are discussed

Procalcitonin Is Not a Reliable Biomarker of Bacterial Coinfection in People With Coronavirus Disease 2019 Undergoing Microbiological Investigation at the Time of Hospital Admission

Abstract Admission procalcitonin measurements and microbiology results were available for 1040 hospitalized adults with coronavirus disease 2019 (from 48 902 included in the International Severe Acute Respiratory and Emerging Infections Consortium World Health Organization Clinical Characterisation Protocol UK study). Although procalcitonin was higher in bacterial coinfection, this was neither clinically significant (median [IQR], 0.33 [0.11–1.70] ng/mL vs 0.24 [0.10–0.90] ng/mL) nor diagnostically useful (area under the receiver operating characteristic curve, 0.56 [95% confidence interval, .51–.60]).</jats:p

Implementation of corticosteroids in treating COVID-19 in the ISARIC WHO Clinical Characterisation Protocol UK:prospective observational cohort study

BACKGROUND: Dexamethasone was the first intervention proven to reduce mortality in patients with COVID-19 being treated in hospital. We aimed to evaluate the adoption of corticosteroids in the treatment of COVID-19 in the UK after the RECOVERY trial publication on June 16, 2020, and to identify discrepancies in care. METHODS: We did an audit of clinical implementation of corticosteroids in a prospective, observational, cohort study in 237 UK acute care hospitals between March 16, 2020, and April 14, 2021, restricted to patients aged 18 years or older with proven or high likelihood of COVID-19, who received supplementary oxygen. The primary outcome was administration of dexamethasone, prednisolone, hydrocortisone, or methylprednisolone. This study is registered with ISRCTN, ISRCTN66726260. FINDINGS: Between June 17, 2020, and April 14, 2021, 47 795 (75·2%) of 63 525 of patients on supplementary oxygen received corticosteroids, higher among patients requiring critical care than in those who received ward care (11 185 [86·6%] of 12 909 vs 36 415 [72·4%] of 50 278). Patients 50 years or older were significantly less likely to receive corticosteroids than those younger than 50 years (adjusted odds ratio 0·79 [95% CI 0·70–0·89], p=0·0001, for 70–79 years; 0·52 [0·46–0·58], p80 years), independent of patient demographics and illness severity. 84 (54·2%) of 155 pregnant women received corticosteroids. Rates of corticosteroid administration increased from 27·5% in the week before June 16, 2020, to 75–80% in January, 2021. INTERPRETATION: Implementation of corticosteroids into clinical practice in the UK for patients with COVID-19 has been successful, but not universal. Patients older than 70 years, independent of illness severity, chronic neurological disease, and dementia, were less likely to receive corticosteroids than those who were younger, as were pregnant women. This could reflect appropriate clinical decision making, but the possibility of inequitable access to life-saving care should be considered. FUNDING: UK National Institute for Health Research and UK Medical Research Council