Glaciers and Global Warming

Ice core and mass balance studies from glaciers, ice caps and ice sheets constitute an ideal medium for monitoring and studying present and past environmental change and, as such, make a valuable contribution to the present debate over anthropogenic forcing of climate. Data derived from 32 years of measurements in the Canadian Arctic show no significant trends in glacier mass balance, ice melt, or snow accumulation, although the mass balance continues to be slightly negative. Models suggest that industrial aerosol loading of the atmosphere should add to the warming effect of greenhouse gases. However, we have found a sharp increase in the concentration of industrial pollutants in snow deposited since the early 1950's which makes the trendless nature of our various time series surprising. Spatial differences in the nature of climatic change may account for the lack of trend in the Queen Elizabeth Islands but encourages similar investigations to this study elsewhere in the circumpolar region. A global warming trend over the past 150 years has been demonstrated from instrumental data and is evident in our ice cores. However, the ice core data and glacier geometry changes in the Canadian Arctic suggest the Arctic warming is more pronounced in summer than winter. The same warming trend is not unique when viewed in the context of changes over the past 10,000 or 100,000 years. This suggests the 150-year trend is part of the natural climate variability.L'analyse des carottes de glace et les mesures du bilan de masse des glaciers, des calottes glaciaires et des indlandsis permettent de déceler des changements environnementaux survenus dans le passé tout en permettant de surveiller les changements actuels. Ces études peuvent contribuer au débat portant sur les conséquences physiques de l'activité humaine sur le climat. Trente-deux ans de données accumulées sur les bilans de masse, la fonte et l'accumulation de neige sur les glaciers de l'Arctique canadien ne montrent aucune tendance significative, bien que les bilans de masse soient quelque peu négatifs. Les modèles prévoient pourtant un réchauffement provoqué par l'apport accru d'aérosols d'origine industrielle. Nous observons une forte augmentation des concentrations de polluants industriels dans la neige déposée depuis les années cinquante, ce qui rend l'absence d'une tendance dans nos observations encore plus surprenante. L'absence d'indices sur un réchauffement dans l'archipel de la Reine-Élisabeth est peut-être simplement attribuable aux variations régionales du changement climatique, un phénomène qui devrait être étudié dans d'autres régions circumpolaires. Depuis 150 ans, une tendance vers un réchauffement à l'échelle planétaire a été observée à partir des données recueillies par les instruments ainsi que dans les carottes de glace. Les données obtenues à partir des carottes de glace et de la géométrie des glaciers semblent indiquer que ce réchauffement est plus marqué l'été que l'hiver. La tendance au réchauffement n'est cependant pas exceptionnelle dans le contexte des 10 000 ou 100 000 dernières années; elle pourrait rendre compte de la variabilité naturelle du climat.Die Analyse von Eisbohrkernen und das Studium der Bilanz der Masse von Gletschem, Eiskappen und Eisdecken sind ein ausgezeichnetes Mittel, um gegenwàrtige und vergangene Umweltverânderungen zu kontrollieren und zu studieren. So kann ein wertvoller Beitrag zur gegenwàrtigen Débatte ùber den Einfluft der menschlichen Aktivitàt auf das Klima geleistet werden. Die Daten, die man durch Messungen ùber 32 Jahre in der kanadischen Arktis gewann, zeigen keine erhebliche Tendenz in der Bilanz der Gletschermasse, Eisschmelze oder Schneeakkumulation, auch wenn die Bilanz der Masse weiter leicht negativ ist. Die Modelle lassen vermuten, da8 die Ladung der Atmosphère mit Industrieaerosolen zum Treibhauseffekt beitrâgt. Jedoch haben wir einen starken Anstieg in der Konzentration industrieller Schadstoffe in dem seit den frùhen fùnfziger Jahren angesammelten Schnee, was das Fehlen einer Tendenz in unseren verschiedenen Zeitabschnitten ùberraschend macht. Ôrtliche Unterschiede in der Natur der Klimawechsel mogen fur das Fehlen einer Tendenz auf den Queen Elizabeth lnseln verantwortlich sein, doch dieser Untersuchung vergleichbare Studien sollten andernorts in der Region um den PoI durchgefùhrt werden. Eine globale Erwàrmungstendenz ùber die vergangenen 150 Jahre konnte mittels instrumenteller Messungen festgestellt werden und ist in unseren Eisbohrkernen sichtbar. Indessen lassen die Eisbohrkerndaten und Verànderungen in der Géométrie der Gletscher in der kanadischen Arktis annehmen, daft die Erwàrmung der Arktis im Sommer deutlicher ist als im Winter. Dièse Erwàrmungstendenz ist nicht auftergewôhnlich, wenn man sie im Kontext der Verânderungen in den letzten 10,000 oder 100,000 Jahren sieht. Die 150 Jahre-Tendenz ist wohl Teil der natùrlichen Klimavariabilitàt

Deep far infrared ISOPHOT survey in "Selected Area 57", I. Observations and source counts

We present here the results of a deep survey in a 0.4 sq.deg. blank field in Selected Area 57 conducted with the ISOPHOT instrument aboard ESAs Infrared Space Observatory (ISO) at both 60 um and 90 um. The resulting sky maps have a spatial resolution of 15 x 23 sq.arcsec. per pixel which is much higher than the 90 x 90 sq.arcsec. pixels of the IRAS All Sky Survey. We describe the main instrumental effects encountered in our data, outline our data reduction and analysis scheme and present astrometry and photometry of the detected point sources. With a formal signal to noise ratio of 6.75 we have source detection limits of 90 mJy at 60 um and 50 mJy at 90 um. To these limits we find cumulated number densities of 5+-3.5 per sq.deg. at 60 um and 14.8+-5.0 per sq.deg.at 90 um. These number densities of sources are found to be lower than previously reported results from ISO but the data do not allow us to discriminate between no-evolution scenarios and various evolutionary models.Comment: 15 pages, 11 figures, accepted by Astronomy & Astrophysic

Spatio-temporal trends in stock mixing of eastern and western Baltic cod in the Arkona Basin and the implications for recruitment

In the Baltic Sea, two genetically distinct cod populations occur, the eastern and the western Baltic cod. Since 2006, cod abundance has increased substantially in the Arkona Basin (SD 24), the potential mixing area between the two stocks management areas, presumably due to spill-over from the eastern stock. In this study, the spatio-temporal dynamics of stock mixing were analysed using shape analysis of archived otoliths. Further, the impact of eastern cod immigration on recruitment in the western Baltic Sea was investigated using hydrographic drift modelling. The percentage of eastern Baltic cod in the Arkona Basin increased from ca. 30% before 2005 to >80% in recent years. Geographic patterns in stock mixing with a pronounced east–west trend suggest that immigration occurs north of Bornholm, but propagates throughout the Arkona Basin. The immigration cannot be attributed to spawning migration, as no seasonal trend in stock mixing was observed. Based on environmental threshold levels for egg survival and time-series of hydrography data, the habitat suitable for successful spawning of eastern cod was estimated to range between 20 and 50% of the maximum possible habitat size, limited by primarily low salinity. Best conditions occurred irregularly in May–end June, interspersed with years where successful spawning was virtually impossible. Using a coupled hydrodynamic modelling and particle-tracking approach, the drift and survival of drifters representing eastern cod eggs was estimated. On average, 19% of the drifters in the Arkona Basin survive to the end of the yolk-sac stage, with mortality primarily after bottom contact due to low salinity. The general drift direction of the surviving larvae was towards the east. Therefore, it is the immigration of eastern cod, rather than larval transport, that contributes to cod recruitment in the western Baltic Sea

Electrocoalescence of water drop trains in oil under constant and pulsatile electric fields

This study addresses the effectiveness of constant and pulsed DC fields in promoting coalescence of dispersed water drops in an oil-continuous phase. For this purpose, a train of drops of relatively uniform size is injected into a stream of flowing sunflower oil. This stream is then admitted to a coalescing section, where an electric field is applied between a pair of ladder-shape bare electrodes. The capability of this device to enhance coalescence of droplets in a chain is investigated at different field intensities, frequencies and waveforms. The effect of the initial inter-droplet separation distance on the process performance is also addressed under constant DC fields. The dominant coalescence mechanism is found to be due to dipole–dipole interaction at low field strength, whereas electrophoresis becomes predominant at higher field strength. Experiments reveal the existence of an optimal frequency, where the average droplet size enlargement is maximized, especially at low field strengths. The droplet size at the outlet of the coalescer is also found to be dependent on the field waveform

Working Group on Biological Parameters (WGBIOP) 2021

The main objective of the Working Group on Biological Parameters (WGBIOP) is to review the status, issues, developments, and quality assurance of biological parameters used in assessment and management. WGBIOP (1) plans workshops, exchanges, and validation studies on a range of biological varia-bles to review the quality of information supplied for stock assessment and improve quality as-surance and training; (2) investigates data availability and develops documentation and methods to improve communication between data collectors and end-users; (3) delivers new and im-proved functionality for the SmartDots platform. Four otolith exchanges and two workshops were completed in 2020–2021 using SmartDots— eight further exchanges are ongoing. Proposed future exchanges and workshops were reviewed and approved. The development of the SmartDots platform proceeded with the inclusion of the maturity, eggs, atresia, fecundity, and larval identification modules into the software version. A live SmartDots tutorial for event coordinators was conducted. Work to further develop quality assurance guidelines—and review national applications of these—progressed. Age and maturity validation studies were reviewed and a new method for prioritizing future validation work was proposed. Progress with the Stock Identification Database (SID) was reviewed, and the potential for creating a WGBIOP library collection and active involvement of WGBIOP in updating FishBase.org data were evaluated. The importance of identifying and documenting links be-tween all relevant databases and document repositories was identified, and a task to address this was initiated. Work on improving the feedback loop between data collectors and stock assessors on the usage and quality of biological parameters in stock assessment continued. Moving forward, WGBIOP aims to continue collaboration with WGALES and WGSMART on the development of the SmartDots platform, encouraging cross-group sharing of skills and ex-perience to optimize results. WGBIOP aims to improve accessibility to its outputs through up-dates to SID and FishBase.org, and the potential creation of a WGBIOP library collection. WGBIOP hopes to improve two-way communication between data collectors and end-users around the quality and utility of biological parameters used in assessment. WGBIOP also aims to amalgamate all validation activities into one coherent workstream.ICE

The effect of general anaesthetics on brain lactate release

The effects of anaesthetic agents on brain energy metabolism may explain their shared neurophysiological actions but remain poorly understood. The brain lactate shuttle hypothesis proposes that lactate, provided by astrocytes, is an important neuronal energy substrate. Here we tested the hypothesis that anaesthetic agents impair the brain lactate shuttle by interfering with astrocytic glycolysis. Lactate biosensors were used to record changes in lactate release by adult rat brainstem and cortical slices in response to thiopental, propofol and etomidate. Changes in cytosolic nicotinamide adenine dinucleotide reduced (NADH) and oxidized (NAD+) ratio as a measure of glycolytic rate were recorded in cultured astrocytes. It was found that in brainstem slices thiopental, propofol and etomidate reduced lactate release by 7.4 ± 3.6% (P < 0.001), 9.7 ± 6.6% (P < 0.001) and 8.0 ± 7.8% (P = 0.04), respectively. In cortical slices, thiopental reduced lactate release by 8.2 ± 5.6% (P = 0.002) and propofol by 6.0 ± 4.5% (P = 0.009). Lactate release in cortical slices measured during the light phase (period of sleep/low activity) was ~25% lower than that measured during the dark phase (period of wakefulness) (326 ± 83 μM vs 430 ± 118 μM, n = 10; P = 0.04). Thiopental and etomidate induced proportionally similar decreases in cytosolic [NADH]:[NAD+] ratio in astrocytes, indicative of a reduction in glycolytic rate. These data suggest that anaesthetic agents inhibit astrocytic glycolysis and reduce the level of extracellular lactate in the brain. Similar reductions in brain lactate release occur during natural state of sleep, suggesting that general anaesthesia may recapitulate some of the effects of sleep on brain energy metabolism

Cellular Growth Kinetics Distinguish a Cyclophilin Inhibitor from an HSP90 Inhibitor as a Selective Inhibitor of Hepatitis C Virus

During antiviral drug discovery, it is critical to distinguish molecules that selectively interrupt viral replication from those that reduce virus replication by adversely affecting host cell viability. In this report we investigate the selectivity of inhibitors of the host chaperone proteins cyclophilin A (CypA) and heat-shock protein 90 (HSP90) which have each been reported to inhibit replication of hepatitis C virus (HCV). By comparing the toxicity of the HSP90 inhibitor, 17-(Allylamino)-17-demethoxygeldanamycin (17-AAG) to two known cytostatic compounds, colchicine and gemcitabine, we provide evidence that 17-AAG exerts its antiviral effects indirectly through slowing cell growth. In contrast, a cyclophilin inhibitor, cyclosporin A (CsA), exhibited selective antiviral activity without slowing cell proliferation. Furthermore, we observed that 17-AAG had little antiviral effect in a non-dividing cell-culture model of HCV replication, while CsA reduced HCV titer by more than two orders of magnitude in the same model. The assays we describe here are useful for discriminating selective antivirals from compounds that indirectly affect virus replication by reducing host cell viability or slowing cell growth