876 research outputs found
Notes of Orchids from Andalucía. II
Notas de Orquídeas de Andalucia II. Palabras clave. Orchidaceae, Andalucía, Espana.Key Words. Orchidaceae, Andalucía, Spain
Curriculum for excellence and the transition to Abertay attributes:the contribution of sport
Scotland’s Curriculum for Excellence (CfE) in schools has been acknowledged as the most significant change in teaching practice in many years (Reeves 2008). At the heart of the CfE lies the desire to develop four capacities within pupils to give individuals the necessary skills for work, life and learning. Abertay University’s curriculum is undergoing change designed to develop “Abertay attributes” in their graduates. Central to both strategies is interdisciplinary learning alongside the contextualisation of lessons to increase levels of engagement, attainment and success. This paper will consider the parallels between CfE and the Abertay Teaching and Learning Strategy, the Scottish Governments policy on attainment and draw conclusions on the role and potential of contextualised learning through the Dundee Academy of Sport project
Curriculum for excellence and the transition to Abertay attributes:the contribution of sport
Scotland’s Curriculum for Excellence (CfE) in schools has been acknowledged as the most significant change in teaching practice in many years (Reeves 2008). At the heart of the CfE lies the desire to develop four capacities within pupils to give individuals the necessary skills for work, life and learning. Abertay University’s curriculum is undergoing change designed to develop “Abertay attributes” in their graduates. Central to both strategies is interdisciplinary learning alongside the contextualisation of lessons to increase levels of engagement, attainment and success. This paper will consider the parallels between CfE and the Abertay Teaching and Learning Strategy, the Scottish Governments policy on attainment and draw conclusions on the role and potential of contextualised learning through the Dundee Academy of Sport project
Practical methods of tracking of nonstationary time series applied to real-world data
In this paper, we discuss some practical implications for implementing adaptable network algorithms applied to non-stationary time series problems. Two real world data sets, containing electricity load demands and foreign exchange market prices, are used to test several different methods, ranging from linear models with fixed parameters, to non-linear models which adapt both parameters and model order on-line. Training with the extended Kalman filter, we demonstrate that the dynamic model-order increment procedure of the resource allocating RBF network (RAN) is highly sensitive to the parameters of the novelty criterion. We investigate the use of system noise for increasing the plasticity of the Kalman filter training algorithm, and discuss the consequences for on-line model order selection. The results of our experiments show that there are advantages to be gained in tracking real world non-stationary data through the use of more complex adaptive models
Preliminary Sunyaev Zel'dovich Observations of Galaxy Clusters with OCRA-p
We present 30 GHz Sunyaev Zel'dovich (SZ) observations of a sample of four
galaxy clusters with a prototype of the One Centimetre Receiver Array (OCRA-p)
which is mounted on the Torun 32-m telescope. The clusters (Cl0016+16,
MS0451.6-0305, MS1054.4-0321 and Abell 2218) are popular SZ targets and serve
as commissioning observations. All four are detected with clear significance
(4-6 sigma) and values for the central temperature decrements are in good
agreement with measurements reported in the literature. We believe that
systematic effects are successfully suppressed by our observing strategy. The
relatively short integration times required to obtain these results demonstrate
the power of OCRA-p and its successors for future SZ studies.Comment: 9 pages, 2 figures. Accepted by MNRAS, online earl
Requirements for a global lidar system: spaceborne lidar with wall-to-wall coverage
Lidar is the optimum technology for measuring bare Earth elevation beneath, and the structure of, vegetation. Consequently airborne laser scanning (ALS) is widely employed for use in a wide range of applications. However, ALS is not available globally nor frequently updated due to its high cost per unit area. Spaceborne lidar can map globally, but energy requirements limit existing spaceborne lidars to sparse sampling missions unsuitable for many common ALS applications. This paper derives the equations to calculate the coverage a lidar satellite could achieve for a given set of characteristics (and released open-source), then uses a cloud map to determine the number of satellites needed to achieve continuous, global coverage within a certain time-frame. Using the characteristics of existing in-orbit technology, a single lidar satellite could have a continuous swath width of 300 m when producing a 30 m resolution map. Consequently 12 satellites would be needed to produce a continuous map every five years, increasing to 418 satellites for 5 m resolution. Building twelve of the currently in-orbit lidar systems is likely to be prohibitively expensive and so the potential of technological developments to lower the cost of a GLS are discussed. Once these technologies achieve a sufficient readiness level, a Global Lidar System could be cost-effectively realised
Metabolic, inflammatory and haemostatic effects of a low-dose continuous combined HRT in women with type 2 diabetes: potentially safer with respect to vascular risk?
BACKGROUND Conventional hormone replacement therapy (HRT) containing conjugated equine oestrogen (CEE) and medroxyprogesterone acetate (MPA) increases triglyceride, C- reactive protein (CRP) and coagulation Factor VII concentrations, potentially explaining their increased coronary heart disease (CHD) and stroke risk. OBJECTIVE To assess the metabolic effects of a continuous combined HRT containing 1 mg oestradiol and 0.5 mg norethisterone or matching placebo. DESIGN Double-blind, randomized placebo-controlled trial. PATIENTS Fifty women with type 2 diabetes. MEASUREMENTS Classical and novel risk factors for vascular disease. RESULTS Triglyceride concentration was not altered (P = 0.31, change in active arm relative to placebo) and low-density lipoprotein (LDL) cholesterol concentration declined 13% (P = 0.018). IL-6 concentration (mean difference -1.42 pg/ml, 95% CI: -2.55 to - 0.29 IU/dl, P = 0.015), Factor VII (-32 IU/dl, -43 to -21 IU/l, P lt 0.001) and tissue plasminogen activator antigen (by 13%, P = 0.005) concentrations fell, but CRP was not significantly altered (P = 0.62). Fasting glucose (P = 0.026) also declined significantly, but there are no significant effects on HBA1c, Factor IX or APC resistance. CONCLUSIONS HRT containing 1 mg oestradiol and 0.5 mg norethisterone may avoid the adverse metabolic effects potentially implicated in the elevated CHD and stroke risk induced by conventional higher dose HRT. This type of preparation may therefore be more suitable than conventional HRT for women at elevated CHD risk such as those with type 2 diabetes. Large randomized controlled trials of such low dose preparations, powered for cardiovascular end points, are now needed
2. Reducing energy demand from buildings, [in:] Shifting the focus: energy demand in a net-zero carbon UK
This chapter sets out the trends and drivers of energy demand in buildings. It also sets out the policy for buildings in the UK and recommendations for government policy and CREDS work
In vitro anthelmintic effects of cysteine proteinases from plants against intestinal helminths of rodents
Infections with gastrointestinal (GI) nematodes are amongst the most prevalent worldwide, especially in tropical climates. Control of these infections is primarily through treatment with anthelmintic drugs, but the rapid development of resistance to all the currently available classes of anthelmintic means that alternative treatments are urgently required. Cysteine proteinases from plants
such as papaya, pineapple and fig are known to be substantially effective against three rodent GI nematodes, Heligmosomoides polygyrus, Trichuris muris and Protospirura muricola, both in vitro and in vivo. Here, based on in vitro motility assays and scanning electron microscopy, we extend these earlier reports, demonstrating the potency of this anthelmintic effect of plant cysteine proteinases against two GI helminths from different taxonomic groups – the canine hookworm, Ancylostoma ceylanicum, and the rodent cestode, Rodentolepis microstoma. In the case of hookworms, a mechanism of action targeting the surface layers of the cuticle indistinguishable from that reported earlier appears to be involved, and in the case of cestodes, the surface of the tegumental layers was also the principal location of damage. Hence, plant cysteine proteinases have a broad spectrum of activity against intestinal helminths (both nematodes and cestodes), a quality that reinforces their suitability for development as a muchneeded novel treatment against GI helminths of humans and livestock
Enzymatic radiosynthesis of a 18F-Glu-Ureido-Lys ligand for the prostate-specific membrane antigen (PSMA)
We thank the Engineering and Physical Sciences Research Council, UK, for a research grant (EP/M01262X/1).Peer reviewedPostprin
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