Perspectives for implementing fisheries certification in developing countries

This paper discusses the future of the Marine Stewardship Council (MSC), a market-based certification program, in developing countries and exposes the challenges and opportunities for fish producers. The MSC needs to attract the interest of more fishing enterprises from these regions to increase its global presence. Because most fisheries in developing countries cannot meet the MSC standards, or afford the certification process costs, it is suggested that there is a need for developing different levels within the MSC system and additional third-party assessing organizations. MSC certification may mean adoption of improvements in fisheries management and approving fishing regimes in developing countries. However, post-certification benefits may decrease as more fisheries become certified

Facing challenges in an ageing world

Editorial.The sponsorship of the following contributors made possible the meeting: Universidad Pablo de Olavide, Centro Andaluz de Biología del Desarrollo, Springer Publishers, International Coenzyme Q10 Association, Sociedad Española de Biología Celular, Universidad Internacional de Andalucía, Junta de Andalucía, Cien por Cien Natural, Pharma Nord Denmark, C. Viral, ThermoFisher Scientific and Cultek.Peer Reviewe

The ENSO signature in sea-surface temperature in the Gulf of California

We analyzed 21 years of sea-surface temperature satellite images to explore the spatial signature of the El Niño-Southern Oscillation signal in the Gulf of California. We used empirical orthogonal function analysis to extract the principal mode of the nonseasonal sea-surface temperature variability and compared it to the spatial signature of the Southern Oscillation Index. The first mode accounted for 80% of nonseasonal variability and its amplitude time series was significantly correlated to the Southern Oscillation Index (r = −0.58,P \u3c 0.01). The amplitude of this mode and its statistical relation to the El Niño is stronger during winter, which suggests that forcing of sea-surface temperature variability occurs through the disruption of the wind-driven upwelling corridor along the eastern coast due to El Niño-related atmospheric teleconnections. We also examined weekly time series of coastal sea-surface temperature coastal anomalies along the coast of North America, including the interior of the Gulf of California, during the strong 1997–98 El Niño. We found a poleward propagating signal that reached the mouth of the Gulf of California at the end of spring and continued its poleward propagation along the west coast of the peninsula slightly delayed; it also resulted in warming inside the Gulf of California. This observation may provide an explanation for the variable extension of the El Niño signature along the Pacific coast of North America

Does low-energy sweetener consumption affect energy intake and body weight? A systematic review, including meta-analyses, of the evidence from human and animal studies

By reducing energy density, low-energy sweeteners (LES) might be expected to reduce energy intake (EI) and body weight (BW). To assess the totality of the evidence testing the null hypothesis that LES exposure (versus sugars or unsweetened alternatives) has no effect on EI or BW, we conducted a systematic review of relevant studies in animals and humans consuming LES with ad libitum access to food energy. In 62 of 90 animal studies exposure to LES did not affect or decreased BW. Of 28 reporting increased BW, 19 compared LES with glucose exposure using a specific ‘learning’ paradigm. Twelve prospective cohort studies in humans reported inconsistent associations between LES use and Body Mass Index (-0.002 kg/m2/year, 95%CI -0.009 to 0.005). Meta-analysis of short- term randomized controlled trials (RCTs, 129 comparisons) showed reduced total EI for LES- versus sugar-sweetened food or beverage consumption before an ad libitum meal (-94 kcal, 95%CI -122 to -66), with no difference versus water (-2 kcal, 95%CI -30 to 26). This was consistent with EI results from sustained intervention RCTs (10 comparisons). Meta-analysis of sustained intervention RCTs (4 weeks to 40 months) showed that consumption of LES versus sugar led to relatively reduced BW (nine comparisons; -1.35 kg, 95%CI –2.28 to - 0.42), and a similar relative reduction in BW versus water (three comparisons; -1.24 kg, 95%CI –2.22 to -0.26). Most animal studies did not mimic LES consumption by humans, and reverse causation may influence the results of prospective cohort studies. The preponderance of evidence from all human RCTs indicates that LES do not increase EI or BW, whether compared with caloric or non-caloric (e.g., water) control conditions. Overall, the balance of evidence indicates that use of LES in place of sugar, in children and adults, leads to reduced EI and BW, and possibly also when compared with water

Physical Examination Tests for Screening and Diagnosis of Cervicogenic Headache: A Systematic Review

It has been suggested that differential diagnosis of headaches should consist of a robust subjective ex-amination and a detailed physical examination of the cervical spine. Cervicogenic headache (CGH) is a form of headache that involves referred pain from the neck. To our knowledge, no studies have sum-marized the reliability and diagnostic accuracy of physical examination tests for CGH. The aim of this study was to summarize the reliability and diagnostic accuracy of physical examination tests used to diagnose CGH. A systematic review following PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines was performed in four electronic databases (MEDLINE, Web of Science, Embase and Scopus). Full text reports concerning physical tests for the diagnosis of CGH which reported the clinometric properties for assessment of CGH, were included and screened for methodological quality. Quality Appraisal for Reliability Studies (QAREL) and Quality Assessment of Studies of Diagnostic Accuracy (QUADAS-2) scores were completed to assess article quality. Eight articles were retrieved for quality assessment and data extraction. Studies investigating diagnostic reliability of physical exami-nation tests for CGH scored poorer on methodological quality (higher risk of bias) than those of diag-nostic accuracy. There is sufficient evidence showing high levels of reliability and diagnostic accuracy of the selected physical examination tests for the diagnosis of CGH. The cervical flexion-rotation test (CFRT) exhibited both the highest reliability and the strongest diagnostic accuracy for the diagnosis of CGH

Hydrophilic surface modification of acrylate-based biomaterials

[EN] Acrylic polymers have proved to be excellent with regard to cell adhesion, colonization and survival, in vitro and in vivo. Highly ordered and regular pore structures thereof can be produced with the help of polyamide templates, which are removed with nitric acid. This treatment converts a fraction of the ethyl acrylate side groups into acrylic acid, turning poly(ethyl acrylate) scaffolds into a more hydrophilic and pH-sensitive substrate, while its good biological performance remains intact. To quantify the extent of such a modification, and be able to characterize the degree of hydrophilicity of poly(ethyl acrylate), poly(ethyl acrylate) was treated with acid for different times (four, nine and 17 days), and compared with poly(acrylic acid) and a 90/10%wt. EA/AAc copolymer (P(EA-co-AAc)). The biological performance was also assessed for samples immersed in acid up to four days and the copolymer, and it was found that the incorporation of acidic units on the material surface was not prejudicial for cells. This surface modification of 3D porous hydrophobic scaffolds makes easier the wetting with culture medium and aqueous solutions in general, and thus represents an advantage in the manageability of the scaffolds.The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: The authors acknowledge financing through project FP7 NMP3-SL-2009-229239 'Regeneration of cardiac tissue assisted by bioactive implants' (RECATABI) and projects MAT2011-28791-C03-02 and -03 from the Spanish Ministerio de Ciencia e Innovacion. This work was also supported by the Spanish Ministry of Education through M. Arnal-Pastor FPU AP2009-1870 grant.Arnal Pastor, MP.; Comín-Cebrián, S.; Martínez-Ramos, C.; Monleón Pradas, M.; Vallés Lluch, A. (2016). Hydrophilic surface modification of acrylate-based biomaterials. Journal of Biomaterials Applications. 30(9):1429-1441. doi:10.1177/0885328215627414S1429144130

Exploiting the Hierarchical Structure of Rule-Based Specifications for Decision Planning

Rule-based specifications have been very successful as a declarative approach in many domains, due to the handy yet solid foundations offered by rule-based machineries like term and graph rewriting. Realistic problems, however, call for suitable techniques to guarantee scalability. For instance, many domains exhibit a hierarchical structure that can be exploited conveniently. This is particularly evident for composition associations of models. We propose an explicit representation of such structured models and a methodology that exploits it for the description and analysis of model- and rule-based systems. The approach is presented in the framework of rewriting logic and its efficient implementation in the rewrite engine Maude and is illustrated with a case study.

A Fixpoint-Based Calculus for Graph-Shaped Computational Fields

Coordination is essential for dynamic distributed systems exhibiting autonomous behaviors. Spatially distributed, locally interacting, propagating computational fields are particularly appealing for allowing components to join and leave with little or no overhead. In our approach, the space topology is represented by a graph-shaped field, namely a network with attributes on both nodes and arcs, where arcs represent interaction capabilities between nodes. We propose a calculus where computation is strictly synchronous and corresponds to sequential computations of fixpoints in the graph-shaped field. Under some conditions, those fixpoints can be computed by synchronised iterations, where in each iteration the attributes of a node is updated based on the attributes of the neighbours in the previous iteration. Basic constructs are reminiscent of the semiring μ-calculus, a semiring-valued generalisation of the modal μ-calculus, which provides a flexible mechanism to specify the neighbourhood range (according to path formulae) and the way attributes should be combined (through semiring operators). Additional control-flow constructs allow one to conveniently structure the fixpoint computations. We illustrate our approach with a case study based on a disaster recovery scenario, implemented in a prototype simulator that we use to evaluate the performance of a disaster recovery strategy

Intradermal and virosomal influenza vaccines for preventing influenza hospitalization in the elderly during the 2011–2012 influenza season: A comparative effectiveness study using the Valencia health care information system

AbstractBackgroundThe use of intradermal vaccination or virosomal vaccines could increase protection against influenza among the vulnerable population of older adults. Studies assessing the comparative effectiveness of these two influenza vaccine types in this age group are lacking.MethodsWe conducted a retrospective cohort study to estimate the comparative effectiveness of intradermal seasonal trivalent-influenza vaccine (TIV) delivered by a microneedle injection system and a virosomal-TIV intramuscularly delivered for prevention of influenza hospitalization in non-institutionalized adults aged ≥65 years. We obtained administrative data on immunization status and influenza hospitalization for the 2011–2012 influenza season, and used Cox regression models to assess comparative effectiveness. We estimated crude and adjusted (age, sex, comorbidity, pharmaceutical claims, recent pneumococcal vaccination and number of hospitalizations for all causes other than influenza between the previous and current influenza seasons) hazard ratios (HR).ResultsOverall, 164,021 vaccinated subjects were evaluated. There were 127 hospitalizations for influenza among 62,058 subjects, contributing 914,740 person-weeks at risk in the virosomal-TIV group, and 133 hospitalizations for influenza among 101,963 subjects, contributing 1,504,570 person-weeks at risk in the intradermal-TIV group. The crude HR of intradermal-TIV relative to virosomal-TIV was 0.64 (95% confidence interval (CI): 0.50–0.81), and the adjusted Cox estimated HR was 0.67 (95% CI: 0.52–0.85).ConclusionsDuring the 2011–2012 influenza season the risk of hospitalization for influenza was reduced by 33% in non-institutionalized elderly adults who were vaccinated with intradermal-TIV compared with virosomal-TIV

The organo-metal-like nature of long-range conduction in cable bacteria

Cable bacteria are filamentous, multicellular microorganisms that display an exceptional form of biological electron transport across centimeter-scale distances. Currents are guided through a network of nickel-containing protein fibers within the cell envelope. Still, the mechanism of long-range conduction remains unresolved. Here, we characterize the conductance of the fiber network under dry and wet, physiologically relevant, conditions. Our data reveal that the fiber conductivity is high (median value: 27 S cm−1; range: 2 to 564 S cm−1), does not show any redox signature, has a low thermal activation energy (Ea = 69 ± 23 meV), and is not affected by humidity or the presence of ions. These features set the nickel-based conduction mechanism in cable bacteria apart from other known forms of biological electron transport. As such, conduction resembles that of an organic semi-metal with a high charge carrier density. Our observation that biochemistry can synthesize an organo-metal-like structure opens the way for novel bio-based electronic technologies. © 2024 The Author