Galaxy Clusters in the Line of Sight to Background Quasars: I. Survey Design and Incidence of MgII Absorbers at Cluster Redshifts

We describe the first optical survey of absorption systems associated with galaxy clusters at z= 0.3-0.9. We have cross-correlated SDSS DR3 quasars with high-redshift cluster/group candidates from the Red-Sequence Cluster Survey. We have found 442 quasar-cluster pairs for which the MgII doublet might be detected at a transverse (physical) distance d<2 Mpc from the cluster centers. To investigate the incidence (dN/dz) and equivalent-width distribution n(W) of MgII systems at cluster redshifts, two statistical samples were drawn out of these pairs: one made of high-resolution spectroscopic quasar observations (46 pairs), and one made of quasars used in MgII searches found in the literature (375 pairs). The results are: (1) the population of strong MgII systems (W_0>2.0 Ang.) near cluster redshifts shows a significant (>3 sigma) overabundance (up to a factor of 15) when compared with the 'field' population; (2) the overabundance is more evident at smaller distances (d<1 Mpc) than larger distances (d<2 Mpc) from the cluster center; and, (3) the population of weak MgII systems (W_0<0.3 Ang.) near cluster redshifts conform to the field statistics. Unlike in the field, this dichotomy makes n(W) in clusters appear flat and well fitted by a power-law in the entire W-range. A sub-sample of the most massive clusters yields a stronger and still significant signal. Since either the absorber number density or filling-factor/cross-section affects the absorber statistics, an interesting possibility is that we have detected the signature of truncated halos due to environmental effects. Thus, we argue that the excess of strong systems is due to a population of absorbers in an overdense galaxy environment, and the lack of weak systems to a different population, that got destroyed in the cluster environment. (Abridged)Comment: Accepted for publication in the Astrophysical Journa

LSST Science Book, Version 2.0

A survey that can cover the sky in optical bands over wide fields to faint magnitudes with a fast cadence will enable many of the exciting science opportunities of the next decade. The Large Synoptic Survey Telescope (LSST) will have an effective aperture of 6.7 meters and an imaging camera with field of view of 9.6 deg^2, and will be devoted to a ten-year imaging survey over 20,000 deg^2 south of +15 deg. Each pointing will be imaged 2000 times with fifteen second exposures in six broad bands from 0.35 to 1.1 microns, to a total point-source depth of r~27.5. The LSST Science Book describes the basic parameters of the LSST hardware, software, and observing plans. The book discusses educational and outreach opportunities, then goes on to describe a broad range of science that LSST will revolutionize: mapping the inner and outer Solar System, stellar populations in the Milky Way and nearby galaxies, the structure of the Milky Way disk and halo and other objects in the Local Volume, transient and variable objects both at low and high redshift, and the properties of normal and active galaxies at low and high redshift. It then turns to far-field cosmological topics, exploring properties of supernovae to z~1, strong and weak lensing, the large-scale distribution of galaxies and baryon oscillations, and how these different probes may be combined to constrain cosmological models and the physics of dark energy.Comment: 596 pages. Also available at full resolution at http://www.lsst.org/lsst/sciboo

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

The SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery

The impact of surgical delay on resectability of colorectal cancer: An international prospective cohort study

AimThe SARS-CoV-2 pandemic has provided a unique opportunity to explore the impact of surgical delays on cancer resectability. This study aimed to compare resectability for colorectal cancer patients undergoing delayed versus non-delayed surgery.MethodsThis was an international prospective cohort study of consecutive colorectal cancer patients with a decision for curative surgery (January-April 2020). Surgical delay was defined as an operation taking place more than 4 weeks after treatment decision, in a patient who did not receive neoadjuvant therapy. A subgroup analysis explored the effects of delay in elective patients only. The impact of longer delays was explored in a sensitivity analysis. The primary outcome was complete resection, defined as curative resection with an R0 margin.ResultsOverall, 5453 patients from 304 hospitals in 47 countries were included, of whom 6.6% (358/5453) did not receive their planned operation. Of the 4304 operated patients without neoadjuvant therapy, 40.5% (1744/4304) were delayed beyond 4 weeks. Delayed patients were more likely to be older, men, more comorbid, have higher body mass index and have rectal cancer and early stage disease. Delayed patients had higher unadjusted rates of complete resection (93.7% vs. 91.9%, P = 0.032) and lower rates of emergency surgery (4.5% vs. 22.5%, P ConclusionOne in 15 colorectal cancer patients did not receive their planned operation during the first wave of COVID-19. Surgical delay did not appear to compromise resectability, raising the hypothesis that any reduction in long-term survival attributable to delays is likely to be due to micro-metastatic disease