Impact of small vessel disease in the brain on gait and balance

Gait and balance impairment is highly prevalent in older people. We aimed to assess whether and how single markers of small vessel disease (SVD) or a combination thereof explain gait and balance function in the elderly. We analysed 678 community-dwelling healthy subjects from the Lothian Birth Cohort 1936 at the age of 71–74 years who had undergone comprehensive risk factor assessment, gait and balance assessment as well as brain MRI. We investigated the impact of individual SVD markers (white matter hyperintensity – WMH, microbleeds, lacunes, enlarged perivascular spaces, brain atrophy) as seen on structural brain MRI and of a global SVD score on the patients’ performance. A regression model revealed that age, sex, and hypertension significantly explained gait speed. Among SVD markers white matter hyperintensity (WMH) score or volume were additional significant and independent predictors of gait speed in the regression model. A similar association was seen with the global SVD score. Our study confirms a negative impact of SVD-related morphologic brain changes on gait speed in addition to age, sex and hypertension independent from brain atrophy. The presence of WMH seems to be the major driving force for SVD on gait impairment in healthy elderly subjects

PROTECT: pervasive and useR fOcused biomeTrics bordEr projeCT. A Case Study

PROTECT: Pervasive and useR fOcused biomeTrics bordEr projeCT is an EU project funded by the Horizon 2020 research and Innovation Programme. The main aim of PROTECT was to build an advanced biometric-based person identification system that works robustly across a range of border crossing types and that has strong user-centric features. This work presents the case study of the multibiometric verification system developed within PROTECT. The system has been developed to be suitable for different borders such as air, sea, and land borders. The system covers two use cases: the walk-through scenario, in which the traveller is on foot; the drive-through scenario, in which the traveller is in a vehicle. Each deployment includes a different set of biometric traits and this paper illustrates how to evaluate such multibiometric system in accordance with international standards and, in particular, how to overcome practical problems that may be encountered when dealing with multibiometric evaluation, such as different score distributions and missing scores

Omega-3 PUFA metabolism and brain modifications during aging

In Canada, 5.5 million (16% of Canadians) adults are >65 years old and projections suggest this number will be approximately 20% of Canadians by 2024. A major concern regarding old age is a decline in health, especially if this entails a loss of self-sufficiency and independence caused by a decline in cognition. The brain contains 60% of fat and is one of the most concentrated organs in long chain omega-3 fatty acids such as docosahexaenoic acid (DHA). During aging, there are physiological modifications in the metabolism of lipids that could also have consequences on brain structure and levels of DHA. This review will hence discuss the physiological modifications in the metabolism of lipids during aging with a focus on long chain omega-3 and omega-6 fatty acids and also outline the structural and functional modifications of the brain during aging including brain lipid modifications and its relation to higher levels of DHA and cognition. Therefore, in this review, we outline the importance of collecting more data on the biology of aging since it might highly improve our understanding about what are «normal» modifications occurring during aging and what can become pathological

Die Europäische Beweisanordnung : ein weiterer Meilenstein auf dem Gebiet der Rechtshilfe?

eingereicht von Martina LinortnerSalzburg, Univ., Dipl.-Arb., 200

Die Europ\ue4ische Beweisanordnung : ein weiterer Meilenstein auf dem Gebiet der Rechtshilfe?

eingereicht von Martina LinortnerSalzburg, Univ., Dipl.-Arb., 200