Temporal evolution of magnetic molecular shocks II. Analytics of the steady state and semi-analytical construction of intermediate ages

In the first paper of this series (Paper I) we computed time dependent simulations of multifluid shocks with chemistry and a transverse magnetic field frozen in the ions, using an adaptive moving grid. In this paper, we present new analytical results on steady-state molecular shocks. Relationships between density and pressure in the neutral fluid are derived for the cold magnetic precursor, hot magnetic precursor, adiabatic shock front, and the following cooling layer. The compression ratio and temperature behind a fully dissociative adiabatic shock is also derived. To prove that these results may even hold for intermediate ages, we design a test to locally characterise the validity of the steady state equations in a time-dependent shock simulation. Applying this tool to the results of Paper I, we show that most of these shocks (all the stable ones) are indeed in a quasi-steady state at all times, i.e. : a given snapshot is composed of one or more truncated steady shock. Finally, we use this property to produce a construction method of any intermediate time of low velocity shocks (u < 20 km/s) with only a steady-state code. In particular, this method allows one to predict the occurrence of steady CJ-type shocks more accurately than previously proposed criteria.Comment: A&A in pres

Non-Maxwellian Proton Velocity Distributions in Nonradiative Shocks

The Balmer line profiles of nonradiative supernova remnant shocks provide the means to measure the post-shock proton velocity distribution. While most analyses assume a Maxwellian velocity distribution, this is unlikely to be correct. In particular, neutral atoms that pass through the shock and become ionized downstream form a nonthermal distribution similar to that of pickup ions in the solar wind. We predict the H alpha line profiles from the combination of pickup protons and the ordinary shocked protons, and we consider the extent to which this distribution could affect the shock parameters derived from H alpha profiles. The Maxwellian assumption could lead to an underestimate of shock speed by up to about 15%. The isotropization of the pickup ion population generates wave energy, and we find that for the most favorable parameters this energy could significantly heat the thermal particles. Sufficiently accurate profiles could constrain the strength and direction of the magnetic field in the shocked plasma, and we discuss the distortions from a Gaussian profile to be expected in Tycho's supernova remnant.Comment: 13 pages, 6 figure

How to diagnose the cause of sudden cardiac arrest

Sudden cardiac death or sudden cardiac arrest (SCA) is defined as natural death that occurs within an hour of the onset of acute symptoms or during sleep due to a primary cardiac cause. Most cases of SCA are attributable to coronary artery disease, with occult cardiomyopathy or inheritable arrhythmic syndromes accounting for a minority of SCA. Diagnosing the cause of SCA has potential implications for the patient and the family, and demands a comprehensive approach. This review summarizes the potential causes of SCA and outlines a systematic diagnostic approach to the SCA survivor. (Cardiol J 2011; 18, 2: 210-216

The Molecular Condensations Ahead of Herbig-Haro Objects. III. Radiative and dynamical perturbations of the HH 2 condensation

We have carried out an extensive observational study (from BIMA data) and made a preliminary theoretical investigation of the molecular gas around HH2. The molecular maps show a very complex morphological, kinematical and chemical structure. The overall main conclusion of this work confirms the findings of Paper I and II, by demonstrating that in addition to the strong photochemical effects caused by penetration of the UV photons from HH2 into molecular cloud, a range of complex radiative and dynamical interactions occur. Thus, despite the apparent `quiescent' nature of the molecular cloud ahead of HH2, the kinematical properties observed within the field of view suggest that it is possibly being driven out by powerful winds from the VLA 1 protostar.Comment: 20 pages. Accepted for publication to Astronomy & Astrophysic

The determinants of election to the United Nations Security Council

This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s11127-013-0096-4.The United Nations Security Council (UNSC) is the foremost international body responsible for the maintenance of international peace and security. Members vote on issues of global importance and consequently receive perks—election to the UNSC predicts, for instance, World Bank and IMF loans. But who gets elected to the UNSC? Addressing this question empirically is not straightforward as it requires a model that allows for discrete choices at the regional and international levels; the former nominates candidates while the latter ratifies them. Using an original multiple discrete choice model to analyze a dataset of 180 elections from 1970 to 2005, we find that UNSC election appears to derive from a compromise between the demands of populous countries to win election more frequently and a norm of giving each country its turn. We also find evidence that richer countries from the developing world win election more often, while involvement in warfare lowers election probability. By contrast, development aid does not predict election

Lineage Divergence and Historical Gene Flow in the Chinese Horseshoe Bat (Rhinolophus sinicus)

PMCID: PMC3581519This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited

Resilient functioning is associated with altered structural brain network topology in adolescents exposed to childhood adversity

Childhood adversity is one of the strongest predictors of adolescent mental illness. Therefore, it is critical that the mechanisms that aid resilient functioning in individuals exposed to childhood adversity are better understood. Here, we examined whether resilient functioning was related to structural brain network topology. We quantified resilient functioning at the individual level as psychosocial functioning adjusted for the severity of childhood adversity in a large sample of adolescents (N = 2406, aged 14–24). Next, we examined nodal degree (the number of connections that brain regions have in a network) using brain-wide cortical thickness measures in a representative subset (N = 275) using a sliding window approach. We found that higher resilient functioning was associated with lower nodal degree of multiple regions including the dorsolateral prefrontal cortex, the medial prefrontal cortex, and the posterior superior temporal sulcus (z > 1.645). During adolescence, decreases in nodal degree are thought to reflect a normative developmental process that is part of the extensive remodeling of structural brain network topology. Prior findings in this sample showed that decreased nodal degree was associated with age, as such our findings of negative associations between nodal degree and resilient functioning may therefore potentially resemble a more mature structural network configuration in individuals with higher resilient functioning

MicroRNAs in cardiac arrhythmia: DNA sequence variation of MiR-1 and MiR-133A in long QT syndrome.

Long QT syndrome (LQTS) is a genetic cardiac condition associated with prolonged ventricular repolarization, primarily a result of perturbations in cardiac ion channels, which predisposes individuals to life-threatening arrhythmias. Using DNA screening and sequencing methods, over 700 different LQTS-causing mutations have been identified in 13 genes worldwide. Despite this, the genetic cause of 30-50% of LQTS is presently unknown. MicroRNAs (miRNAs) are small (∼ 22 nucleotides) noncoding RNAs which post-transcriptionally regulate gene expression by binding complementary sequences within messenger RNAs (mRNAs). The human genome encodes over 1800 miRNAs, which target about 60% of human genes. Consequently, miRNAs are likely to regulate many complex processes in the body, indeed aberrant expression of various miRNA species has been implicated in numerous disease states, including cardiovascular diseases. MiR-1 and MiR-133A are the most abundant miRNAs in the heart and have both been reported to regulate cardiac ion channels. We hypothesized that, as a consequence of their role in regulating cardiac ion channels, genetic variation in the genes which encode MiR-1 and MiR-133A might explain some cases of LQTS. Four miRNA genes (miR-1-1, miR-1-2, miR-133a-1 and miR-133a-2), which encode MiR-1 and MiR-133A, were sequenced in 125 LQTS probands. No genetic variants were identified in miR-1-1 or miR-133a-1; but in miR-1-2 we identified a single substitution (n.100A> G) and in miR-133a-2 we identified two substitutions (n.-19G> A and n.98C> T). None of the variants affect the mature miRNA products. Our findings indicate that sequence variants of miR-1-1, miR-1-2, miR-133a-1 and miR-133a-2 are not a cause of LQTS in this cohort