304 research outputs found
Water Volume Detection System in Galon using Arduino
Internet of things has a concept that aims to expand
the benefits connected in a continuous internet connection on an
ongoing basis. The method used by Internet of Things is
automatic control without distance. Implementation currently
gallon control of water is still done by looking at the state of
gallons and then gallons turn when the water in the gallon is
already empty. With the internet of things can be implemented a
water volume detector that can monitor the state of the gallon
from a distance through a smartphone. To make the manufacture
of water volume detection required tools such as water flow
sensors, microcontroller or other tools that are then connected to
the internet.
For interaction relationship of water flow sensor,
microcontroller, or other tool of help through internet used
Android application. This Android application is used to facilitate
users to access the internet anywhere. This Android application is
made by using Android studio and microcontroller made with
Arduino programming using C language. Microcontroller used is
WeMos D1 R2 which has been contained ESP8266 in it.
The result of this water volume detection development is the
microcontroller can transmit sensor data to the Ubidots server so
that the application can retrieve sensor data on the Ubidots
server. Users can view the gallon state in real time and are also
given a notification when the gallon water volume is below alert
level. Users can also view reports of gallons per month
Morbidity after surgical management of cervical cancer in low and middle income countries: A systematic review and meta-analysis
Objective: To investigate morbidity for patients after the primary surgical management of cervical cancer in low and middle-income countries (LMIC).
Methods: The Pubmed, Cochrane, the Cochrane Central Register of Controlled Trials, Embase, LILACS and CINAHL were searched for published studies from 1st Jan 2000 to 30th June 2017 reporting outcomes of surgical management of cervical cancer in LMIC. Randomeffects meta-analytical models were used to calculate pooled estimates of surgical complications including blood transfusions, ureteric, bladder, bowel, vascular and nerve injury, fistulae and thromboembolic events. Secondary outcomes included five-year progression free (PFS) and overall survival (OS).
Findings: Data were available for 46 studies, including 10,847 patients from 11 middle income countries. Pooled estimates were: blood transfusion 29% (95%CI 0.19–0.41, P = 0.00, I 2 = 97.81), nerve injury 1% (95%CI 0.00–0.03, I 2 77.80, P = 0.00), bowel injury, 0.5% (95%CI 0.01–0.01, I 2 = 0.00, P = 0.77), bladder injury 1% (95%CI 0.01–0.02, P = 0.10, I 2 = 32.2), ureteric injury 1% (95%CI 0.01–0.01, I 2 0.00, P = 0.64), vascular injury 2% (95% CI 0.01– 0.03, I 2 60.22, P = 0.00), fistula 2% (95%CI 0.01–0.03, I 2 = 77.32, P = 0.00,), pulmonary embolism 0.4% (95%CI 0.00–0.01, I 2 26.69, P = 0.25), and infection 8% (95%CI 0.04–0.12, 2 95.72, P = 0.00). 5-year PFS was 83% for laparotomy, 84% for laparoscopy and OS was 85% for laparotomy cases and 80% for laparoscopy.
Conclusion: This is the first systematic review and meta-analysis of surgical morbidity in cervical cancer in LMIC, which highlights the limitations of the current data and provides a benchmark for future health services research and policy implementation
Distinct hippocampal engrams control extinction and relapse of fear memory
Learned fear often relapses after extinction, suggesting that extinction training generates a new memory that coexists with the original fear memory; however, the mechanisms governing the expression of competing fear and extinction memories remain unclear. We used activity-dependent neural tagging to investigate representations of fear and extinction memories in the dentate gyrus. We demonstrate that extinction training suppresses reactivation of contextual fear engram cells while activating a second ensemble, a putative extinction engram. Optogenetic inhibition of neurons that were active during extinction training increased fear after extinction training, whereas silencing neurons that were active during fear training reduced spontaneous recovery of fear. Optogenetic stimulation of fear acquisition neurons increased fear, while stimulation of extinction neurons suppressed fear and prevented spontaneous recovery. Our results indicate that the hippocampus generates a fear extinction representation and that interactions between hippocampal fear and extinction representations govern the suppression and relapse of fear after extinction.We thank J. Dunsmoor for comments on the manuscript. A.F.L. was supported by NIH F31 MH111243 and NIH T32 MH106454. S.L.S. was supported by PD/BD/128076/2016 from the Portuguese Foundation for Science and Technology. Research supported by NIH DP5 OD017908 and New York Stem Cell Science (NYSTEM) C-029157 to C.A.D., NIH R01 MH102595 and NIH R21 EY026446 to M.R.
Transcriptomic responses of oil palm (Elaeis guineensis) stem to waterlogging at plantation in relation to precipitation seasonality
Global warming-induced climate change causes significant agricultural problems by increasing the incidence of drought and flooding events. Waterlogging is an inevitable consequence of these changes but its effects on oil palms have received little attention and are poorly understood. Recent waterlogging studies have focused on oil palm seedlings, with particular emphasis on phenology. However, the transcriptomic waterlogging response of mature oil palms remains elusive in real environments. We therefore investigated transcriptomic changes over time in adult oil palms at plantations over a two-year period with pronounced seasonal variation in precipitation. A significant transcriptional waterlogging response was observed in the oil palm stem core but not in leaf samples when gene expression was correlated with cumulative precipitation over two-day periods. Pathways and processes upregulated or enriched in the stem core response included hypoxia, ethylene signaling, and carbon metabolism. Post-waterlogging recovery in oil palms was found to be associated with responses to heat stress and carotenoid biosynthesis. Nineteen transcription factors (TFs) potentially involved in the waterlogging response of mature oil palms were also identified. These data provide new insights into the transcriptomic responses of planted oil palms to waterlogging and offer valuable guidance on the sensitivity of oil palm plantations to future climate changes
Design of entertainment mobile robot: IDAP
Robotic system applications have advanced dramatically over the past few years. This paper presents the IDAP Robot, which is designed and fabricated by taking the first Malaysia robot games festival or Robofest 2002. Development of the IDAP Robot based on the contest regulation to place out the beach balls into the cylinder tubes. This paper focuses on strategies motion of the IDAP robot. The strategies that involve are; it can carry out eighteen beach balls in one time and it is able to place all the cylinder tubes in one track within 3 minutes. The structure design of the robot is divided into two parts namely hardware and software parts. The hardware part involves the design and development of the platform module, storage module, arm manipulator module, power supply module, permanent magnet DC motor, sensing system, control panel, circuit protection and programmable logic controller (PLC). The platform module is divided into three parts namely, Y-axis design, Z-axis design and θ-axis design
Affordable dye sensitizer by waste
Abstract The development of dye sensitizer is growing in line with the increasing demand for renewable energy. A research to obtain a dye sensitizer that is economical, safe, and produces a great value of DSSC efficiency is a challenge unresolved. On the other hand, the efforts for waste reduction are also intensively conducted to create better environment. In this paper, the variation of synthetic dye wastes from batik industries have been successfully applied as dye sensitizer and fabricated on DSSC cells. Congo red (1.0133%) yielded higher efficiency than rhodamine B (0.0126%), methyl orange (0.7560%), and naphthol blue black (0.0083%). The divergence of the efficiency of DSSC is very dependent upon the chromophore group owned by dye. This study has proven that the more chromophore group possessed by dye, the higher the efficiency of DSSC generated. This research concludes that the dye wastes have a bright future to be implemented as dye sensitizer on solar cells
Linking behaviour and climate change in intertidal ectotherms: insights from littorinid snails
A key element missing from many predictive models of the impacts of climate change on intertidal ectotherms is the role of individual behaviour. In this synthesis, using
littorinid snails as a case study, we show how thermoregulatory behaviours may buffer changes in environmental temperatures. These behaviours include either a flight response, to escape the most extreme conditions and utilize warmer or cooler environments; or a fight response, where individuals modify their own environments
to minimize thermal extremes. A conceptual model, generated from studies of littorinid snails, shows that various flight and fight thermoregulatory behaviours may allow an individual to widen its thermal safety margin (TSM) under warming or cooling environmental conditions and hence increase species’ resilience to climate change. Thermoregulatory behaviours may also buffer sublethal fitness impacts associated with thermal stresses. Through this synthesis, we emphasise that future studies need to consider not only animals' physiological limits but also their capacities to buffer the impact of climate change through behavioural responses. Current generalizations, made largely on physiological limits of species, often neglect the buffering effects of behaviour and may, therefore, provide an over-estimation of vulnerability, and consequently poor prediction of the potential impacts of climate change on intertidal ectotherms
Global food systems: addressing malnutrition through sustainable system pathways
Addressing malnutrition (in all its forms) whilst developing a global food system compatible with
environmental sustainability remains one of the most pressing challenges of the 21st century. The
current framing of our food systems fails to fully capture the inequities in production, distribution,
efficiency and sufficiency of all components necessary to end malnutrition. This research presents a
holistic, scalable and replicable framework to model food system pathways (across all essential
nutritional components, including macronutrients, micronutrients and amino acids), providing
quantification of production, losses, allocation and conversions at all stages of the value chain.
Furthermore, this framework attempts to translate current food metrics—often presented in tonnage
or absolute terms—into daily per capita figures to provide important context for how this translates
into food security and nutrition. This framework can be applied at global, regional and national levels.
Here, this model is first presented at a global level and then focuses on India as a national-level
example. Results highlight that, at a global level, we produce the equivalent of 5800 kilocalories and
170 grams of protein per person per day through crops alone. However, major system inefficiencies
mean that less than half of crop calories and protein are delivered (or converted) for final food supply.
Pathway inefficiencies are even more acute for micronutrients; more than 60% of all essential
micronutrients assessed in this study are lost between production and consumer-available phases of
the food supply system. Globally we find very large inequalities in per capita levels of food production,
ranging from 19,000 kilocalories (729 grams of protein) per person per day in North America to 3300
kilocalories (80 grams of protein) in Africa. Large variations are also seen in terms of food system
efficiency, ranging from 15-20% in North America to 80-90% in Africa. Understanding regional
inefficiencies, inequalities and trade imbalances will be crucial to meet the needs of a growing global
population. This case is exemplified in India-specific framework results. India’s domestic production
capacity would result in severe malnutrition across a large proportion (>60%) of the population (even
under ambitious yield and waste reduction scenarios) in 2030/50. This shortfall will have to be
addressed through optimised intervention and trade developments.
This work also explores a number of solutions which couple improved nutritional outcomes with
sustainability. Analyses of global and national nutritional guidelines conclude that most are
incompatible with climate targets; the recommended USA or Australian diet provides minimal
emissions savings relative to the business-as-usual diet in 2050. Low-cost, high-quality protein will
remain a crucial element in developing an effective and sustainable food system. This research
explores the potential of two sources. Results find that meat substitute products have significant
health and emission benefits, but are strongly sensitive to both price and consumer acceptability. The
environmental impact of aquaculture is strongly species-dependent. This study provides the first
quantification of global greenhouse gas emissions from aquaculture, estimated to be 227±61 MtCO2e
(approximately 3-4% of total livestock emissions). This is projected to increase to 365±99MtCO2e by
2030
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