106 research outputs found
Influence of Life Skills on Sexual Behaviorin Adolescent at Seberang Ulu Area of Palembang City
Background: Sex is an aspect that is important for the development of adolescent. Mobility and construction of various facilities in Palembang city, especially Seberang Ulu area is increasing. Increased development raises its own dilemma, on one side the people in dire needs of development, but on the other side occurs that changed the moral decline in adolescent values, norms and lifestyles are followed by a media revolution and an increasingly independent behavior. This study aims to determine the influence of life skills on sexual behavior in adolescents. This research was done in May-June 2011 in the Seberang Ulu Area. Methods: This is quantitative research with cross sectional approach. The subject were all of adolescents aged 12-21 years in Seberang Ulu area of Palembang City with 96 respondents sample. The statistical test used chi square test by using SPSS version 17 program. Result: The results showed that there is the influence of life skills (p = 0.015), hard skills (knowledge of sex) (p = 0.012), soft skills (religiosity, self-confidence, and self-concept) (p = 0.000) towards sexual behavior in adolescent, partially religiosity (p = 0.015), confidence (p = 0.018), and self-concept (p = 0.027) also influence of sex behavior. Conclusion: Life skills, soft skills, religiosity, self-confidence, and self-concept is a risk factor while the hard skills is preventing factor of free sex in adolescents. We need a development model life skills-based education for free sex prevention
Effect of air movement on the thermal insulation of avian nests
Capsule: Air movement over a nest increases the rate of cooling within the nest cup but the walls
provide good thermal insulation.
Aims: This study compared nests of six bird species of the families Fringillidae and Motacillidae to
investigate the insulative properties in still and moving air treatments. It was hypothesized that
differences in nest size and moving air would differ between species and would have a
significant effect on insulatory values of the nests.
Methods: Nest dimensions were measured for a total of 35 nests from six species. Thermal
properties of the nests were recorded using temperature loggers within nests placed in a wind
tunnel under still and moving air conditions.
Results: Insulatory values and internal nest cooling rates were significantly increased by moving air.
There was no significant difference between species for the thermal properties of nests but nest
mass correlated with greater insulatory values and a lower rate of cooling within the nest cup.
Nest wall thickness had no significant effect on the thermal characteristics of the nests.
Conclusion: The use of a constructed nest mitigated the effects of air movement but the
differences between species reflected difference in nest mass rather than wall thickness
Expanding the Social Security Net in South Africa: Opportunities, Challenges and Constraints
Rapid increases in government expenditure on social security between 2000 and 2006 has further increased poor households’ reliance on welfare grants and has been important in the fight against poverty. Already there is evidence of a substitution taking place within the social budget: expenditure on education and health seems to have declined in favour of increased welfare transfer expenditure
A proposed architecture and method of operation for improving the protection of privacy and confidentiality in disease registers
BACKGROUND: Disease registers aim to collect information about all instances of a disease or condition in a defined population of individuals. Traditionally methods of operating disease registers have required that notifications of cases be identified by unique identifiers such as social security number or national identification number, or by ensembles of non-unique identifying data items, such as name, sex and date of birth. However, growing concern over the privacy and confidentiality aspects of disease registers may hinder their future operation. Technical solutions to these legitimate concerns are needed. DISCUSSION: An alternative method of operation is proposed which involves splitting the personal identifiers from the medical details at the source of notification, and separately encrypting each part using asymmetrical (public key) cryptographic methods. The identifying information is sent to a single Population Register, and the medical details to the relevant disease register. The Population Register uses probabilistic record linkage to assign a unique personal identification (UPI) number to each person notified to it, although not necessarily everyone in the entire population. This UPI is shared only with a single trusted third party whose sole function is to translate between this UPI and separate series of personal identification numbers which are specific to each disease register. SUMMARY: The system proposed would significantly improve the protection of privacy and confidentiality, while still allowing the efficient linkage of records between disease registers, under the control and supervision of the trusted third party and independent ethics committees. The proposed architecture could accommodate genetic databases and tissue banks as well as a wide range of other health and social data collections. It is important that proposals such as this are subject to widespread scrutiny by information security experts, researchers and interested members of the general public, alike
The Impact of Growth and Redistribution on Poverty and Inequality in South Africa
This country study evaluates the experience of the South African economy with respect to growth, poverty and inequality trends since the advent of democracy in 1994
Nucleoside/nucleotide reverse transcriptase inhibitor sparing regimen with once daily integrase inhibitor plus boosted darunavir is non-inferior to standard of care in virologically-suppressed children and adolescents living with HIV – Week 48 results of the randomised SMILE Penta-17-ANRS 152 clinical trial
The genetic architecture of the human cerebral cortex
The cerebral cortex underlies our complex cognitive capabilities, yet little is known about the specific genetic loci that influence human cortical structure. To identify genetic variants that affect cortical structure, we conducted a genome-wide association meta-analysis of brain magnetic resonance imaging data from 51,665 individuals. We analyzed the surface area and average thickness of the whole cortex and 34 regions with known functional specializations. We identified 199 significant loci and found significant enrichment for loci influencing total surface area within regulatory elements that are active during prenatal cortical development, supporting the radial unit hypothesis. Loci that affect regional surface area cluster near genes in Wnt signaling pathways, which influence progenitor expansion and areal identity. Variation in cortical structure is genetically correlated with cognitive function, Parkinson's disease, insomnia, depression, neuroticism, and attention deficit hyperactivity disorder
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The impact of PICALM genetic variations on reserve capacity of posterior cingulate in AD continuum
Phosphatidylinositolbinding clathrin assembly protein (PICALM) gene is one novel genetic player associated with late-onset Alzheimer’s disease (LOAD), based on recent genome wide association studies (GWAS). However, how it affects AD occurrence is still unknown. Brain reserve hypothesis highlights the tolerant capacities of brain as a passive means to fight against neurodegenerations. Here, we took the baseline volume and/or thickness of LOAD-associated brain regions as proxies of brain reserve capacities and investigated whether PICALM genetic variations can influence the baseline reserve capacities and the longitudinal atrophy rate of these specific regions using data from Alzheimer’s Disease Neuroimaging Initiative (ADNI) dataset. In mixed population, we found that brain region significantly affected by PICALM genetic variations was majorly restricted to posterior cingulate. In sub-population analysis, we found that one PICALM variation (C allele of rs642949) was associated with larger baseline thickness of posterior cingulate in health. We found seven variations in health and two variations (rs543293 and rs592297) in individuals with mild cognitive impairment were associated with slower atrophy rate of posterior cingulate. Our study provided preliminary evidences supporting that PICALM variations render protections by facilitating reserve capacities of posterior cingulate in non-demented elderly
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Early role of vascular dysregulation on late-onset Alzheimer's disease based on multifactorial data-driven analysis
Multifactorial mechanisms underlying late-onset Alzheimer's disease (LOAD) are poorly characterized from an integrative perspective. Here spatiotemporal alterations in brain amyloid-β deposition, metabolism, vascular, functional activity at rest, structural properties, cognitive integrity and peripheral proteins levels are characterized in relation to LOAD progression. We analyse over 7,700 brain images and tens of plasma and cerebrospinal fluid biomarkers from the Alzheimer's Disease Neuroimaging Initiative (ADNI). Through a multifactorial data-driven analysis, we obtain dynamic LOAD–abnormality indices for all biomarkers, and a tentative temporal ordering of disease progression. Imaging results suggest that intra-brain vascular dysregulation is an early pathological event during disease development. Cognitive decline is noticeable from initial LOAD stages, suggesting early memory deficit associated with the primary disease factors. High abnormality levels are also observed for specific proteins associated with the vascular system's integrity. Although still subjected to the sensitivity of the algorithms and biomarkers employed, our results might contribute to the development of preventive therapeutic interventions
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