Binary properties of CH and Carbon-Enhanced Metal-Poor stars

The HERMES spectrograph installed on the 1.2-m Mercator telescope has been used to monitor the radial velocity of 13 low-metallicity carbon stars, among which 7 Carbon-Enhanced Metal-Poor (CEMP) stars and 6 CH stars. All stars but one show clear evidence for binarity. New orbits are obtained for 8 systems. The sample covers an extended range in orbital periods, extending from 3.4 d (for the dwarf carbon star HE 0024-2523) to about 54 yr (for the CH star HD 26, the longest known among barium, CH and extrinsic S stars). Three systems exhibit low-amplitude velocity variations with periods close to 1 yr superimposed on a long-term trend. In the absence of an accurate photometric monitoring of these systems, it is not clear yet whether these variations are the signature of a very low-mass companion, or of regular envelope pulsations. The period - eccentricity (P - e) diagram for the 40 low-metallicity carbon stars with orbits now available shows no difference between CH and CEMP-s stars (the latter corresponding to those CEMP stars enriched in s-process elements, as are CH stars). We suggest that they must be considered as one and the same family and that their different names only stem from historical reasons. Indeed, these two families have as well very similar mass-function distributions, corresponding to companions with masses in the range 0.5 - 0.7 Msun, indicative of white-dwarf companions, adopting 0.8 - 0.9 Msun for the primary component. This result confirms that CH and CEMP-s stars obey the same mass-transfer scenario as their higher-metallicity analogs, the barium stars. The P - e diagrams of barium, CH and CEMP-s stars are indeed very similar. They reveal two different groups of systems: one with short orbital periods (P < 1000 d) and mostly circular or almost circular orbits, and another with longer-period and eccentric (e > 0.1) orbits.Comment: Accepted in Astronomy & Astrophysic

Structural and Luminescence Properties of Silica-Based Hybrids Containing New Silylated-Diketonato Europium(III) Complex

A new betadiketonate ligand displaying a trimethoxysilyl group as grafting function and a diketone moiety as complexing site (TTA-Si = 4,4,4-trifluoro-2-(3-trimethoxysilyl)propyl)-1-3-butanedione (C4H3S)COCH[(CH2)3Si(OCH3)3]COCF3) and its highly luminescent europium(III) complex [Eu(TTA-Si)3] have been synthesized and fully characterized. Luminescent silica-based hybrids have been prepared as well with this new complex grafted on the surface of dense silica nanoparticles (28 (+/-3 nm) or on mesoporous silica particles. The covalent bonding of Eu(TTA-Si)3 inside the core of uniform silica nanoparticles (40 (+/- 5 nm) was also achieved. Luminescence properties are discussed in relation to the europium chemical environment involved in each of the three hybrids. The general methodology proposed allowed high grafting ratios and overcame chelate release and tendency to agglomeration, and it could be applied to any silica matrix (in the core or at the surface, nanosized or not, dense or mesoporous) and therefore numerous applications such as luminescent markers and luminophors could be foreseen

Chronic myocardial infarction promotes atrial action potential alternans, afterdepolarisations and fibrillation

Aims: Atrial fibrillation (AF) is increased in patients with heart failure resulting from myocardial infarction (MI). We aimed to determine the effects of chronic ventricular MI in rabbits on the susceptibility to AF, and underlying atrial electrophysiological and Ca2+-handling mechanisms. Methods and results: In Langendorff-perfused rabbit hearts, under beta-adrenergic-stimulation with isoproterenol (1 µM; ISO), 8 weeks MI decreased AF threshold, indicating increased AF-susceptibility. This was associated with increased atrial action potential duration-alternans at 90% repolarisation, by 147%, and no significant change in mean APD or atrial global conduction velocity (n=6-13 non-MI hearts, 5-12 MI). In atrial isolated myocytes, also under beta-stimulation, L-type Ca2+ current (ICaL) density and intracellular Ca2+-transient amplitude were decreased by MI, by 35% and 41%, respectively, and the frequency of spontaneous depolarisations (SDs) was substantially increased. MI increased atrial myocyte size and capacity, and markedly decreased transverse-tubule density. In non-MI hearts perfused with ISO, the ICaL-blocker nifedipine, at a concentration (0.02 µM) causing an equivalent ICaL-reduction (35%) to that from the MI, did not affect AF-susceptibility, and decreased APD. Conclusion: chronic MI in rabbits remodels atrial structure, electrophysiology and intracellular Ca2+-handling. Increased susceptibility to AF by MI, under beta-adrenergic-stimulation, may result from associated production of atrial APD-alternans and SDs, since steady-state APD and global conduction velocity were unchanged under these conditions, and may be unrelated to the associated reduction in whole-cell ICaL. Future studies may clarify potential contributions of local conduction changes, and cellular and sub-cellular mechanisms of alternans, to the increased AF-susceptibility

Ice core evidence for a 20th century increase in surface mass balance in coastal Dronning Maud Land, East Antarctica

Ice cores provide temporal records of surface mass balance (SMB). Coastal areas of Antarctica have relatively high and variable SMB, but are under-represented in records spanning more than 100 years. Here we present SMB reconstruction from a 120 m-long ice core drilled in 2012 on the Derwael Ice Rise, coastal Dronning Maud Land, East Antarctica. Water stable isotope (δ18O and δD) stratigraphy is supplemented by discontinuous major ion profiles and continuous electrical conductivity measurements. The base of the ice core is dated to AD 1759 ± 16, providing a climate proxy for the past  ∼ 250 years. The core's annual layer thickness history is combined with its gravimetric density profile to reconstruct the site's SMB history, corrected for the influence of ice deformation. The mean SMB for the core's entire history is 0.47 ± 0.02 m water equivalent (w.e.) a−1. The time series of reconstructed annual SMB shows high variability, but a general increase beginning in the 20th century. This increase is particularly marked during the last 50 years (1962–2011), which yields mean SMB of 0.61 ± 0.01 m w.e. a−1. This trend is compared with other reported SMB data in Antarctica, generally showing a high spatial variability. Output of the fully coupled Community Earth System Model (CESM) suggests that, although atmospheric circulation is the main factor influencing SMB, variability in sea surface temperatures and sea ice cover in the precipitation source region also explain part of the variability in SMB. Local snow redistribution can also influence interannual variability but is unlikely to influence long-term trends significantly. This is the first record from a coastal ice core in East Antarctica to show an increase in SMB beginning in the early 20th century and particularly marked during the last 50 years

Особливості урбаністичного хронотопу в поезіях літугруповання “Бу-Ба-Бу”

Стаття присвячена дослідженню особливостей урбаністичного хронотопу в поезіях Ю. Андруховича, О. Ірванця, В. Неборака. Встановлено, що характерними модифікаціями урбаністичного хронотопу у творчості Ю. Андруховича є топографічний хронотоп із домінантами Львова й Станіслава та карнавалізоване Місто; у поезіях В. Неборака варіації урбаністичного хронотопу створюються за допомогою використання традиційних атрибутів міста, а також власне міських прошарків населення; урбаністичний хронотоп у поезіях О. Ірванця є найменше матеріалізованим і тяжіє до психологічно-метафізичного. Ключові слова: часопростір, хронотоп, топос, урбанізм, карнавалізація.Статья посвящена изучению особенностей урбанистического хронотопа в поэзиях Ю. Андруховича, А. Ирванца, В. Неборака. Так, в творчестве Ю. Андруховича были выявлены такие модификации урбанистического хронотопа, как топографический с доминантами Львова и Станислава и карнавальный Город; в поэзиях В. Неборака вариации урбанистического хронотопа осуществляются при помощи использования традиционных атрибутов города, а также собственно городских слоев населения; урбанистический хронотоп поэзий А. Ирванца наименее материализован и тяготеет к психологически-метафизическому. Ключевые слова: пространственно-временное единство, хронотоп, топос, урбанистичность, карнавальность.The article is dedicated to the study of the urbanism chronotope’s particularities in Yu. Andruhovicha, A. Irvanca, V. Neboraka poetry. So in Yu. Andruhovich’s work. Such modification urbanism chronotope as topographical one with the Livov and Stanislav’s dominant and the carnival one. In V. Neboraka’s variations of urbanism chronotope are realized using the traditional city attributes and town population layers as well. A. Irvanc’s poetry urbanism chronotope is less materialired and strongly attracted by psychological-metaphysical one. Keywords: space-time unity, chronotope, urbanism, carnivalization

Development of novel adenoviral vectors to overcome challenges observed with HAdV-5 based constructs

Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in pre-clinical models and clinical trials over the last two decades. However, the thorough understanding of the HAdV-5 interaction with human subjects has uncovered major concerns about its product applicability. High vector-associated toxicity and widespread pre-existing immunity have been shown to significantly impede the effectiveness of HAdV-5 mediated gene transfer. It is therefore that the in depth knowledge attained working on HAdV-5 is currently being used to develop alternative vectors. Here, we provide a comprehensive overview of data obtained in recent years disqualifying the HAdV-5 vector for systemic gene delivery as well as novel strategies being pursued to overcome the limitations observed with particular emphasis on the ongoing vectorization efforts to obtain vectors based on alternative serotypes

Energetics of surface melt in West Antarctica

We use reanalysis data and satellite remote sensing of cloud properties to examine how meteorological conditions alter the surface energy balance to cause surface melt that is detectable in satellite passive microwave imagery over West Antarctica. This analysis can detect each of the three primary mechanisms for inducing surface melt at a specific location: thermal blanketing involving sensible heat flux and/or longwave heating by optically thick cloud cover, all-wave radiative enhancement by optically thin cloud cover, and f&ouml;hn winds. We examine case studies over Pine Island and Thwaites glaciers, which are of interest for ice shelf and ice sheet stability, and over Siple Dome, which is more readily accessible for field work. During January 2015 over Siple Dome we identified a melt event whose origin is an all-wave radiative enhancement by optically thin clouds. During December 2011 over Pine Island and Thwaites glaciers, we identified a melt event caused mainly by thermal blanketing from optically thick clouds. Over Siple Dome, those same 2011 synoptic conditions yielded a thermal-blanketing-driven melt event that was initiated by an impulse of sensible heat flux and then prolonged by cloud longwave heating. The December 2011 synoptic conditions also generated f&ouml;hn winds at a location on the Ross Ice Shelf adjacent to the Transantarctic Mountains, and we analyze this case with additional support from automatic weather station data. In contrast, a late-summer thermal blanketing period over Pine Island and Thwaites glaciers during February 2013 showed surface melt initiated by cloud longwave heating and then prolonged by enhanced sensible heat flux. One limitation thus far with this type of analysis involves uncertainties in the cloud optical properties. Nevertheless, with improvements this type of analysis can enable quantitative prediction of atmospheric stress on the vulnerable Antarctic ice shelves in a steadily warming climate. &nbsp;</p