Toward an Unsupervised Colorization Framework for Historical Land Use Classification

International audienceWe present an unsupervised colorization framework to improve both the visualization and the automatic land use clas-sification of historical aerial images. We introduce a novel algorithm built upon a cyclic generative adversarial neural network and a texture replacement method to homogeneously and automatically colorize unpaired VHR images. We apply our framework on historical aerial images acquired in France between 1970 and 1990. We demonstrate that our approach helps to disentangle hard to classify land use classes and hence improves the overall land use classification

Les survivants de la Shoah d’Europe centrale et orientale

Après la Seconde Guerre mondiale, plusieurs dizaines de milliers de réfugiés juifs d’Europe centrale et orientale arrivent en France, souvent clandestinement, dans une situation de grande détresse matérielle et sanitaire. Ces survivants de la Shoah ne veulent plus vivre dans leur pays d’origine marqué par trop de souffrances, voire par la poursuite des persécutions. Pour la plupart d’entre eux, la France ne représente toutefois qu’une simple étape vers un autre pays d’installation. Ce n’est d..

Method for orthorectification of terrestrial radar maps

International audienceThe vehicle-based PELICAN radar system is used in the context of mobile mapping. The R-SLAM algorithm allows simultaneous retrieval of the vehicle trajectory and of the map of the environment. As the purpose of PELICAN is to provide a means for gathering spatial information, the impact of distortion caused by the topography is not negligible. This article proposes an orthorectification process to correct panoramic radar images and the consequent R-SLAM trajectory and radar map. The a priori knowledge of the area topography is provided by a digital elevation model. By applying the method to the data obtained from a path with large variations in altitude it is shown that the corrected panoramic radar images are contracted by the orthorectification process. The efficiency of the orthorectification process is assessed firstly by comparing R-SLAM trajectories to a GPS trajectory and secondly by comparing the position of Ground Control Points on the radar map with their GPS position. The RMS positioning error moves from 5.56 m for the raw radar map to 0.75 m for the orthorectified radar map

Implicit Representations of the Human Intestines for Surgery Simulation

International audienceIn this paper, we propose a modeling of the intestines by implicit surfaces for abdominal surgery simulation. The difficulty of such a simulation comes from the animation of the intestines. As a matter of fact, the intestines are a very long tube that is not isotropically elastic, and that bends over itself at various spots, creating multiple self-contacts. We use a multiple component model for the intestines: The first component is a mechanical model of their axis; the second component is a specific sphere-based model to manage collisions and self-collisions; and the third component is a skinning model to define their volume. This paper focuses on the better representation for skinning the intestines. We compare two implicit models: Surfaces defined by point-skeletons and convolution surfaces. A direct application of this simulation is the training of a typical surgical gesture to move apart the intestines in order to reach certain areas of the abdomen

Residential exposure to solar ultraviolet radiation and incidence of childhood hematological malignancies in France

Few studies have investigated the relationship between solar ultraviolet radiation (UV) and childhood hematological malignancies (CHM). This study addresses the associations between residential UV exposure at diagnosis and the incidence of types and subtypes of CHM, by age and gender, in France, over a long period, on the fine scale of the 36,326 Communes that constitute mainland France. The 9,082 cases of acute leukemia and 3,563 cases of lymphoma diagnosed before the age of 15 years from 1990 to 2009 were provided by the French National Registry of Childhood Hematological Malignancies. The incidence of CHM was calculated by Commune, year, age and gender and expressed as the standardized incidence ratio (SIR). UV data from 1988 to 2007 were extracted from the EUROSUN database. The annual daily average UV exposure of the children ranged from 85.5 to 137.8 J/cm2. For each additional 25 J/cm2, there was a significant increase in precursor B-cell acute lymphoblastic leukemia (PBC-ALL) in children aged less than 5 years (SIR 1.18; 95 % CI 1.10–1.27). Further analysis of PBC-ALL in the young children suggested a better fit of models with a threshold, with the risk increasing above 100 J/cm2, for which the SIR was 1.24 (95 % CI 1.14–1.36) for a 25 J/cm2 increase. The results remained stable in analyses stratifying by deprivation index or degree of urbanization of the Communes. The study suggests that higher residential UV exposure may be positively associated with a higher incidence of PBC-ALL in early childhood

Chemical and structural investigations on uranium oxide-based microparticles as reference materials for analytical measurements

The analysis of individual micrometre- and submicrometre-sized particles collected by IAEA’s safeguards inspectors on swipe samples during in-field verification activities requires the implementation of a sustainable quality control system such as suitable microparticulate reference materials. To this end, pure and neodymium-doped uranium oxide-based microparticles utilising an aerosol-based particle production process were prepared. SEM/EDX measurements confirmed the monodispersity of the produced microspheres as well as the incorporation of 15 mol% Nd into the compound particles. The timeline of structural investigations mirror the ongoing alteration of particles being stored under laboratory atmosphere. While results from in-SEM Raman (CEA, DAM) on microparticles after two years storage time point to the formation of U3O8 and a minor fraction of schoepite phase (hydrated UO3), in U L3-edge XAFS after four months storage time and U M4-edge HR-XANES after ten months storage time spectra (INE-Beamline and ACT station @ KIT synchrotron radiation source) mainly U(IV) and U(V), respectively, was observed. These results provide new insight into ageing mechanism of the microparticles after preparation. From these results important conclusions with respect to storage conditions and shelf life of the reference particles can be drawn. The first batch of pure U-oxide microparticles produced in Juelich was successfully certified regarding the isotopic composition and the U amount per particle and applied in an international laboratory exercise NUSIMEP-9

Mémento pour la gestion des projets d'assainissement : fascicule 3 : les eaux pluviales

Ce fascicule aborde la gestion des eaux pluviales à deux niveaux : celui de la planification, du fait de l’importance de cette réflexion amont (fiche « enjeux d’urbanisme et d’aménagement »), et celui du projet d'aménagement, public ou privé, de type rénovation urbaine, création de lotissement, de ZAC, de zone industrielle, … Il ne traite pas le projet pluvial "isolé" du projet d'aménagement (création ou réhabilitation de collecteur, dispositif de traitement des eaux pluviales, …). Il insiste sur l’importance de prendre en compte la gestion des eaux pluviales très à l’amont du projet et en associant très tôt l’ensemble des acteurs de l’aménagement

Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection

Natural killer (NK) cell maturation is a tightly controlled process that endows NK cells with functional competence and the capacity to recognize target cells. Here, we found that the transcription factor (TF) Zeb2 was the most highly induced TF during NK cell maturation. Zeb2 is known to control epithelial to mesenchymal transition, but its role in immune cells is mostly undefined. Targeted deletion of Zeb2 resulted in impaired NK cell maturation, survival, and exit from the bone marrow. NK cell function was preserved, but mice lacking Zeb2 in NK cells were more susceptible to B16 melanoma lung metastases. Reciprocally, ectopic expression of Zeb2 resulted in a higher frequency of mature NK cells in all organs. Moreover, the immature phenotype of Zeb2(-/-) NK cells closely resembled that of Tbx21(-/-) NK cells. This was caused by both a dependence of Zeb2 expression on T-bet and a probable cooperation of these factors in gene regulation. Transgenic expression of Zeb2 in Tbx21(-/-) NK cells partially restored a normal maturation, establishing that timely induction of Zeb2 by T-bet is an essential event during NK cell differentiation. Finally, this novel transcriptional cascade could also operate in human as T-bet and Zeb2 are similarly regulated in mouse and human NK cells

Bmcc1s, a Novel Brain-Isoform of Bmcc1, Affects Cell Morphology by Regulating MAP6/STOP Functions

The BCH (BNIP2 and Cdc42GAP Homology) domain-containing protein Bmcc1/Prune2 is highly enriched in the brain and is involved in the regulation of cytoskeleton dynamics and cell survival. However, the molecular mechanisms accounting for these functions are poorly defined. Here, we have identified Bmcc1s, a novel isoform of Bmcc1 predominantly expressed in the mouse brain. In primary cultures of astrocytes and neurons, Bmcc1s localized on intermediate filaments and microtubules and interacted directly with MAP6/STOP, a microtubule-binding protein responsible for microtubule cold stability. Bmcc1s overexpression inhibited MAP6-induced microtubule cold stability by displacing MAP6 away from microtubules. It also resulted in the formation of membrane protrusions for which MAP6 was a necessary cofactor of Bmcc1s. This study identifies Bmcc1s as a new MAP6 interacting protein able to modulate MAP6-induced microtubule cold stability. Moreover, it illustrates a novel mechanism by which Bmcc1 regulates cell morphology