Öffentliche Sportförderung: Eine ordnungspolitische Betrachtung

An unmittelbaren Transferleistungen fließen jährlich rund 3,9 Mrd. Euro in die staatliche Sportförderung. Wie ist die öffentliche Sportförderung ordnungspolitisch zu bewerten? Welche Wirkungen hat sie auf die Sportanbieter und den Wettbewerb? --

Normal values of the sagittal diameter of the lumbar spine (vertebral body and dural sac) in children measured by MRI

Background: The definition of normal values is a prerequisite for the reliable evaluation of abnormality in the lumbar spine, such as spinal canal stenosis or dural ectasia in patients with Marfan syndrome. Values for vertebral body diameter (VBD) and dural sac diameter (DSD) for the lumbar spine have been published in adults. In children, normal values have been established using conventional radiography or myelography, but not by MRI. Objective: To define normal values for the sagittal diameter of the vertebral body and dural sac, and to calculate a dural sac ratio (DSR) in the lumbosacral spine (L1-S1) in healthy children using MRI. Materials and methods: A total of 75 healthy children between 6years and 17years of age were examined using a sagittal T2-weighted sequence. Sagittal VBD and DSD were measured and a DSR was calculated. This was a retrospective and cross-sectional study. Results: With increasing age there is a significant increase of VBD, a slight increase of DSD, and a slight decrease of DSR. There is no significant sex difference. DSR in healthy children is higher than in healthy adults. Conclusions: MRI is a reliable method demonstrating the natural shape of the lumbosacral spine and its absolute values. These normal values compare well with those established by conventional radiological techniques. Our data may serve as a reference for defining dural ectasia in children with Marfan syndrom

Eye tracking in the wild: Piloting a real-life assessment paradigm for older adults

Previous research showed associations between personality traits and eye movements of young adults in the laboratory. However, less is known about these associations in real life and in older age. Primarily, there seems to be no paradigm to assess eye movements of older adults in real life. The present feasibility study thus aimed to test grocery shopping as a real-life assessment paradigm with older adults. Additionally, possible links between personality traits and eye movements were explored. The sample consisted of 38 older individuals (M = 72.85 years). Participants did their grocery shopping in a supermarket while wearing an eye tracker. Three key feasibility issues were examined, that is (1) wearability of the eye tracker during grocery shopping, (2) recording, and (3) evaluation of eye movements in a real-life context. Our real-life assessment paradigm showed to be feasible to implement and acceptable to older adults. This feasibility study provides specific practical recommendations which may be useful for fu-ture studies that plan to innovatively expand the traditional methods repertoire of personality science and aging research by using eye tracking in real life

Eye Tracking in the Wild: Piloting a Real-Life Assessment Paradigm for Older Adults

Previous research showed associations between personality traits and eye movements of young adults in the laboratory. However, less is known about these associations in real life and in older age. Primarily, there seems to be no paradigm to assess eye movements of older adults in real life. The present feasibility study thus aimed to test grocery shopping as a real-life assessment paradigm with older adults. Additionally, possible links between personality traits and eye movements were explored. The sample consisted of 38 older individuals (M = 72.85 years). Participants did their grocery shopping in a supermarket while wearing an eye tracker. Three key feasibility issues were examined, that is (1) wearability of the eye tracker during grocery shopping, (2) recording, and (3) evaluation of eye movements in a real-life context. Our real-life assessment paradigm showed to be feasible to implement and acceptable to older adults. This feasibility study provides specific practical recommendations which may be useful for future studies that plan to innovatively expand the traditional methods repertoire of personality science and aging research by using eye tracking in real life

Multidirectional flow analysis by cardiovascular magnetic resonance in aneurysm development following repair of aortic coarctation

Aneurysm formation is a life-threatening complication after operative therapy in coarctation. The identification of patients at risk for the development of such secondary pathologies is of high interest and requires a detailed understanding of the link between vascular malformation and altered hemodynamics. The routine morphometric follow-up by magnetic resonance angiography is a well-established technique. However, the intrinsic sensitivity of magnetic resonance (MR) towards motion offers the possibility to additionally investigate hemodynamic consequences of morphological changes of the aorta

BCG Induced Necrosis of the Entire Bladder Urothelium

AbstractInstillation therapy with attenuated tuberculosis bacteria (BCG) can significantly reduce rates of recurrence of non-muscle invasive bladder cancer. Local and systemic side effects such as dysuria, irritative voiding symptoms or partial bladder contracture and systemic inflammation were reported. A 75 year-old male patient with recurrent non muscle invasive bladder cancer developed necrosis of the entire bladder urothelium more than six years after BCG instillation immunotherapy. The resulting irritative voiding symptoms and low bladder capacity required radical cystectomy. BCG instillation can cause severe side effects, which develop gradually and eventually need radical surgical therapy such as cystectomy without tumor recurrence

Atmospheric dynamics and the mass loss process in red supergiant stars

Red supergiant stars represent a key phase in the evolution of massive stars. Recent radiative hydrodynamic simulations suggest that their atmospheres may be the location of large-scale convective motions. As supergiant convection is expected to generate supersonic motions and shocks, we seek constraints on these atmospheric motions and their possible relation with mass-loss rates. We present high-resolution, visible spectroscopy of a sample of red supergiants (spectral type M I) and analyse them with a tomographic technique. We observe steep velocity gradients, characterising both upward and downward supersonic motions, which are time variable on time scales of a few hundred days. These convective motions will generate turbulent pressure, which will strongly decrease the effective gravity. We suggest that this decrease, combined with radiative pressure on molecular lines, initiate the mass loss in red supergiant stars.Comment: Accepted by Astronomy and Astrophysics. 12 pages, 14 figure

Frequency ratio method for seismic modeling of Gamma Doradus stars

A method for obtaining asteroseismological information of a Gamma Doradus oscillating star showing at least three pulsation frequencies is presented. This method is based on a first-order asymptotic g-mode expression, in agreement with the internal structure of Gamma Doradus stars. The information obtained is twofold: 1) a possible identification of the radial order n and degree l of observed frequencies (assuming that these have the same l), and 2) an estimate of the integral of the buoyancy frequency (Brunt-Vaisala) weighted over the stellar radius along the radiative zone. The accuracy of the method as well as its theoretical consistency are also discussed for a typical Gamma Doradus stellar model. Finally, the frequency ratios method has been tested with observed frequencies of the Gamma Doradus star HD 12901. The number of representative models verifying the complete set of constraints (the location in the HR diagram, the Brunt-Vaisala frequency integral, the observed metallicity and frequencies and a reliable identification of n and l) is drastically reduced to six.Comment: 11 pages, 12 figure

Interaction of MDM33 with mitochondrial inner membrane homeostasis pathways in yeast

Membrane homeostasis affects mitochondrial dynamics, morphology, and function. Here we report genetic and proteomic data that reveal multiple interactions of Mdm33, a protein essential for normal mitochondrial structure, with components of phospholipid metabolism and mitochondrial inner membrane homeostasis. We screened for suppressors of MDM33 overexpression-induced growth arrest and isolated binding partners by immunoprecipitation of cross-linked cell extracts. These approaches revealed genetic and proteomic interactions of Mdm33 with prohibitins, Phb1 and Phb2, which are key components of mitochondrial inner membrane homeostasis. Lipid profiling by mass spectrometry of mitochondria isolated from Mdm33-overexpressing cells revealed that high levels of Mdm33 affect the levels of phosphatidylethanolamine and cardiolipin, the two key inner membrane phospholipids. Furthermore, we show that cells lacking Mdm33 show strongly decreased mitochondrial fission activity indicating that Mdm33 is critical for mitochondrial membrane dynamics. Our data suggest that MDM33 functionally interacts with components important for inner membrane homeostasis and thereby supports mitochondrial division

Atmospheric Abundances in Post-AGB candidates of Intermediate Temperature

Detailed atmospheric abundances have been calculated for a sample of A-G supergiant stars with IR fluxes and/or high galactic latitudes. HD 172481 and HD 158616 show clear indications of being post-AGB stars that have experienced third dredge-up. HD 158616 is carbon-rich while the abundance pattern of HD 172481 and its large Li enhancement gives support to the hot bottom burning scenario that explains paucity of carbon-rich stars among AGB stars. HD 172324 is very likely a hot post-AGB star that shows a strong carbon deficiency. HD 725, HD 218753 and HD 331319 also appear to be evolved objects between the red giant and the AGB. HD 9167, HD 173638 with a few exceptions, reflect solar abundances and no signs of post red giant evolution. They are most likely young massive disk supergiants. Further analysis of proto-Planetary Nebula HDE 341617 reveals that He lines show signs of velocity stratification. The emission lines have weakened considerably since 1993. The envelope expands at 19 km s$^{-1}$ relative to the star. Atmospheric abundances, evolutionary tracks and isochrones are used to estimate masses and ages of all stars in the sample.Comment: 19 pages (text), 14 tables, 5 figure